Sanguinarine induces apoptosis of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and caspase-9-dependent pathway

International Journal of Toxicology

Volumn 31, Issue 1, 2012, Pages 70-77

  Lee, Jun Sik ^a   Jung, Won Kyo ^a   Jeong, Myung Ho ^b   Yoon, Taek Rim ^b   Kim, Hyung Keun ^b  

^a Chosun University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Bax Bcl 2 ratio; caspase; human colon cancer cells; sanguinarine

Indexed keywords

CASPASE 3; CASPASE 9; PROTEIN BAX; PROTEIN BCL 2; SANGUINARINE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL NUCLEUS; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NUCLEAR CONDENSATION; PROTEIN EXPRESSION; REGULATORY MECHANISM;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOPHENANTHRIDINES; CASPASE 3; CASPASE 9; CELL PROLIFERATION; CELL SURVIVAL; COLONIC NEOPLASMS; HT29 CELLS; HUMANS; ISOQUINOLINES; PROTO-ONCOGENE PROTEINS C-BCL-2;

SANGUINARIA; SANGUINARIA CANADENSIS;

EID: 84863145554     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581811423845     Document Type: Article

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