Carthamus tinctorius L. prevents LPS-induced TNFα signaling activation and cell apoptosis through JNK1/2-NFκB pathway inhibition in H9c2 cardiomyoblast cells

Journal of Ethnopharmacology

Volumn 130, Issue 3, 2010, Pages 505-513

  Tien, Yun Chen ^a   Lin, Jing Ying ^b   Lai, Chao Hung ^c   Kuo, Chia Hua ^d   Lin, Wen Yuan ^a   Tsai, Chang Hai ^e   Tsai, Fuu Jen ^a   Cheng, Yi Chang ^f   Peng, Wen Huang ^a   Huang, Chih Yang ^a,e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^d UNIVERSITY OF TAIPEI   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

^f TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Carthamus tinctorius L.; H9c2 cardiomyoblast apoptosis; JNK; Lipopolysaccharide; TNF

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; SAFFLOWER EXTRACT; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA; CARDIOTONIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE 9; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MITOCHONDRIAL MEMBRANE POTENTIAL; MYOBLAST; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CHEMISTRY; CHINESE MEDICINE; DOSE RESPONSE; DRUG EFFECTS; FLOWER; HEART MUSCLE CELL; ISOLATION AND PURIFICATION; METABOLISM; RAT; SAFFLOWER; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; CARTHAMUS TINCTORIUS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOWERS; LIPOPOLYSACCHARIDES; MEDICINE, CHINESE TRADITIONAL; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MYOCYTES, CARDIAC; NF-KAPPA B; PLANT EXTRACTS; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ASTERACEAE; CARTHAMUS TINCTORIUS; FLOS;

EID: 77954954234     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.038     Document Type: Article

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