Flufenamic acid suppresses epileptiform activity in hippocampus by reducing excitatory synaptic transmission and neuronal excitability

Epilepsia

Volumn 51, Issue 3, 2010, Pages 384-390

  Fernández, Miriam ^a   Lao Peregrín, Cristina ^a   Martín, Eduardo D ^a  

^a University of Castilla La Mancha   (Spain)

Author keywords

Fenamates; Glutamate release; NMDA; Non NMDA; NSAIDs; Synaptic transmission

Indexed keywords

4 AMINOPYRIDINE; FLUFENAMIC ACID; MAGNESIUM;

ACTION POTENTIAL; AMPLITUDE MODULATION; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN PERFUSION; CONTROLLED STUDY; DRUG MECHANISM; EPILEPTIC DISCHARGE; EXPERIMENTAL MODEL; GABAERGIC TRANSMISSION; HIPPOCAMPUS; NERVE EXCITABILITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPSE; SYNAPTIC TRANSMISSION;

4-AMINOPYRIDINE; ACTION POTENTIALS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICONVULSANTS; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIALS; FLUFENAMIC ACID; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIALS; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 77749246057     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2009.02279.x     Document Type: Article

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