Inhibition of the calcium-activated chloride current in cardiac ventricular myocytes by N-(p-amylcinnamoyl)anthranilic acid (ACA)

Biochemical and Biophysical Research Communications

Volumn 402, Issue 3, 2010, Pages 531-536

  Gwanyanya, Asfree ^a   Macianskiene, Regina ^a,b   Bito, Virginie ^c   Sipido, Karin R ^c   Vereecke, Johan ^a   Mubagwa, Kanigula ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Calcium activated; Cardiac; Chloride channel; Diclofenac; N (p amylcinnamoyl)anthranilic acid

Indexed keywords

4 BROMOPHENACYL BROMIDE; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ANTHRANILIC ACID DERIVATIVE; CALCIUM ION; CHLORIDE CHANNEL; CYCLIC AMP; DICLOFENAC; FLUFENAMIC ACID; N (4 AMYLCINNAMOYL)ANTHRALINILIC ACID; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; CONTROLLED STUDY; HEART MUSCLE CELL; IC 50; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; ROOM TEMPERATURE; SWINE; WHOLE CELL;

ANIMALS; ANTHRANILIC ACIDS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALCIUM; CALCIUM CHANNELS, L-TYPE; CHLORIDE CHANNELS; CHLORIDES; CINNAMATES; ENZYME INHIBITORS; HEART VENTRICLES; MYOCYTES, CARDIAC; PHOSPHOLIPASES A2; SWINE;

SUIDAE;

EID: 78549284852     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.069     Document Type: Article

References (27)

1. Hartzell C., Putzier I., Arreola J. Calcium-activated chloride channels. Annu. Rev. Physiol. 2005, 67:719-758.
2. Zygmunt A.C., Gibbons W.R. Properties of the calcium-activated chloride current in heart. J. Gen. Physiol. 1992, 99:391-414.
3. Hiraoka M., Kawano S. Calcium-sensitive and insensitive transient outward current in rabbit ventricular myocytes. J. Physiol. 1989, 410:187-212.
4. Tseng G.N., Hoffman B.F. Two components of transient outward current in canine ventricular myocytes. Circ. Res. 1989, 64:633-647.
5. Zygmunt A.C., Gibbons W.R. Calcium-activated chloride current in rabbit ventricular myocytes. Circ. Res. 1991, 68:424-437.
6. i-dependent chloride current in single Purkinje cells from rabbit heart. J. Physiol. 1993, 468:641-667.
7. Kenyon J.L., Gibbons W.R. 4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers. J. Gen. Physiol. 1979, 73:139-157.
8. Cl(Ca) contribute to isoproterenol-induced delayed after depolarizations in midmyocardial cells. Am. J. Physiol. 1998, 275:H1979-H1992.
9. 2+ exchange in rabbit cardiac Purkinje fibres. J. Physiol. 1992, 456:19-38.
10. Eggermont J. Calcium-activated chloride channels: (un)known, (un)loved?. Proc. Am. Thorac. Soc. 2004, 1:22-27.
11. Doughty J.M., Miller A.L., Langton P.D. Non-specificity of chloride channel blockers in rat cerebral arteries: block of the L-type calcium channel. J. Physiol. 1998, 507(Pt. 2):433-439.
12. - currents in rabbit pulmonary artery smooth muscle cells. J. Physiol. 2002, 539:119-131.
13. 2+ from an intracellular store in rat pulmonary artery smooth muscle cells. Br. J. Pharmacol. 2003, 140:1442-1450.
14. Liantonio A., Giannuzzi V., Picollo A., Babini E., Pusch M., Conte Camerino D. Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium. Br. J. Pharmacol. 2007, 150:235-247.
15. 2 and insulin secretion in pancreatic islets. Biochim. Biophys. Acta 1992, 1135:215-220.
16. 2 dependence of the magnesium-inhibited, TRPM7-like cation channel in cardiac myocytes. Am. J. Physiol. Cell Physiol. 2006, 291:C627-C635.
17. Macianskiene R., Moccia F., Sipido K.R., Flameng W., Mubagwa K. Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells. Am. J. Physiol. Heart Circ. Physiol. 2002, 282:H1879-H1888.
18. Gwanyanya A., Amuzescu B., Zakharov S.I., Macianskiene R., Sipido K.R., Bolotina V.M., Vereecke J., Mubagwa K. Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation. J. Physiol. 2004, 559:761-776.
19. G.R. Li, X.L. Du, Y.L. Siow, K. O, H.F. Tse, C.P. Lau, Calcium-activated transient outward chloride current and phase 1 repolarization of swine ventricular action potential, Cardiovasc. Res. 58 (2003) 89-98.
20. Bahinski A., Nairn A.C., Greengard P., Gadsby D.C. Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes. Nature 1989, 340:718-721.
21. i-dependent membrane currents in guinea-pig ventricular cells in the absence of Na/Ca exchange. Pflugers Arch. 1995, 430:871-878.
22. Schultz J.H., Volk T., Bassalay P., Hennings J.C., Hubner C.A., Ehmke H. Molecular and functional characterization of Kv4.2 and KChIP2 expressed in the porcine left ventricle. Pflugers Arch. 2007, 454:195-207.
23. Macianskiene R., Gwanyanya A., Sipido K.R., Vereecke J., Mubagwa K. Induction of a novel cation current in cardiac ventricular myocytes by flufenamic acid and related drugs. Br. J. Pharmacol. 2010, 161:416-429.
24. Verkerk A.O., Veldkamp M.W., Baartscheer A., Schumacher C.A., Klopping C., van Ginneken A.C., Ravesloot J.H. Ionic mechanism of delayed afterdepolarizations in ventricular cells isolated from human end-stage failing hearts. Circulation 2001, 104:2728-2733.
25. +. Cardiovasc. Res. 1999, 41:175-187.
26. Kraft R., Grimm C., Frenzel H., Harteneck C. Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid. Br. J. Pharmacol. 2006, 148:264-273.
27. Clapham D.E. Snapshot: mammalian TRP channels. Cell 2007, 129:220.