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Volumn 12, Issue 6, 2013, Pages 987-999

Tumor-suppressive effects of CDK8 in endometrial cancer cells

Author keywords

Cell growth; Cell migration; Cyclin dependent kinae 8 (CDK8); Endometrial cancer; Tumorigenesis

Indexed keywords

CYCLIN DEPENDENT KINASE 8;

EID: 84875208009     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24003     Document Type: Article
Times cited : (41)

References (53)
  • 1
    • 71049169616 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: A family portrait
    • PMID:19884882
    • Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, et al. Cyclin-dependent kinases: a family portrait. Nat Cell Biol 2009; 11:1275-6; PMID:19884882; http://dx.doi.org/10.1038/ncb1109-1275
    • (2009) Nat Cell Biol , vol.11 , pp. 1275-1276
    • Malumbres, M.1    Harlow, E.2    Hunt, T.3    Hunter, T.4    Lahti, J.M.5    Manning, G.6
  • 2
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • PMID:19238148
    • Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009; 9:153-66; PMID:19238148; http://dx.doi.org/10. 1038/nrc2602
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 3
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks, and microprocessors
    • PMID:9442875
    • Morgan DO. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 1997; 13:261-91; PMID:9442875; http://dx.doi.org/10.1146/annurev.cellbio.13.1.261
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 4
    • 27544470656 scopus 로고    scopus 로고
    • Mammalian cyclindependent kinases
    • PMID:16236519
    • Malumbres M, Barbacid M. Mammalian cyclindependent kinases. Trends Biochem Sci 2005; 30:630-41; PMID:16236519; http://dx.doi.org/10.1016/j.tibs. 2005.09.005
    • (2005) Trends Biochem Sci , vol.30 , pp. 630-641
    • Malumbres, M.1    Barbacid, M.2
  • 5
    • 8644219655 scopus 로고    scopus 로고
    • Living with or without cyclins and cyclin-dependent kinases
    • PMID:15545627
    • Sherr CJ, Roberts JM. Living with or without cyclins and cyclin-dependent kinases. Genes Dev 2004; 18:2699-711; PMID:15545627; http://dx.doi.org/10.1101/ gad.1256504
    • (2004) Genes Dev , vol.18 , pp. 2699-2711
    • Sherr, C.J.1    Roberts, J.M.2
  • 6
    • 52949111487 scopus 로고    scopus 로고
    • CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity
    • PMID:18794900
    • Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, et al. CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 2008; 455:547-51; PMID:18794900; http://dx.doi.org/10.1038/nature07179
    • (2008) Nature , vol.455 , pp. 547-551
    • Firestein, R.1    Bass, A.J.2    Kim, S.Y.3    Dunn, I.F.4    Silver, S.J.5    Guney, I.6
  • 7
    • 78650816688 scopus 로고    scopus 로고
    • The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
    • PMID:21179167
    • Kapoor A, Goldberg MS, Cumberland LK, Ratnakumar K, Segura MF, Emanuel PO, et al. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature 2010; 468:1105-9; PMID:21179167; http://dx.doi.org/ 10.1038/nature09590
    • (2010) Nature , vol.468 , pp. 1105-1109
    • Kapoor, A.1    Goldberg, M.S.2    Cumberland, L.K.3    Ratnakumar, K.4    Segura, M.F.5    Emanuel, P.O.6
  • 9
    • 77954759030 scopus 로고    scopus 로고
    • The human Mediator complex: A versatile, genome-wide regulator of transcription
    • PMID:20299225
    • Taatjes DJ. The human Mediator complex: a versatile, genome-wide regulator of transcription. Trends Biochem Sci 2010; 35:315-22; PMID:20299225; http://dx.doi.org/10.1016/j.tibs.2010.02.004
    • (2010) Trends Biochem Sci , vol.35 , pp. 315-322
    • Taatjes, D.J.1
  • 10
    • 18844451820 scopus 로고    scopus 로고
    • Mediator and the mechanism of transcriptional activation
    • PMID:15896740
    • Kornberg RD. Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 2005; 30:235-9; PMID:15896740; http://dx.doi.org/10.1016/j. tibs.2005.03.011
    • (2005) Trends Biochem Sci , vol.30 , pp. 235-239
    • Kornberg, R.D.1
  • 11
    • 79953162883 scopus 로고    scopus 로고
    • Function and regulation of the Mediator complex
    • PMID:21330129
    • Conaway RC, Conaway JW. Function and regulation of the Mediator complex. Curr Opin Genet Dev 2011; 21:225-30; PMID:21330129; http://dx.doi.org/10.1016/j. gde.2011.01.013
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 225-230
    • Conaway, R.C.1    Conaway, J.W.2
  • 12
    • 18844378166 scopus 로고    scopus 로고
    • The mammalian Mediator complex and its role in transcriptional regulation
    • PMID:15896743
    • Conaway RC, Sato S, Tomomori-Sato C, Yao T, Conaway JW. The mammalian Mediator complex and its role in transcriptional regulation. Trends Biochem Sci 2005; 30:250-5; PMID:15896743; http://dx.doi.org/10.1016/j.tibs.2005.03.002
    • (2005) Trends Biochem Sci , vol.30 , pp. 250-255
    • Conaway, R.C.1    Sato, S.2    Tomomori-Sato, C.3    Yao, T.4    Conaway, J.W.5
  • 13
    • 18844394569 scopus 로고    scopus 로고
    • Dynamic regulation of pol II transcription by the mammalian Mediator complex
    • PMID:15896744
    • Malik S, Roeder RG. Dynamic regulation of pol II transcription by the mammalian Mediator complex. Trends Biochem Sci 2005; 30:256-63; PMID:15896744; http://dx.doi.org/10.1016/j.tibs.2005.03.009
    • (2005) Trends Biochem Sci , vol.30 , pp. 256-263
    • Malik, S.1    Roeder, R.G.2
  • 14
    • 2942610696 scopus 로고    scopus 로고
    • A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II
    • PMID:15175151
    • Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell 2004; 14:553-7; PMID:15175151; http://dx.doi.org/10.1016/j.molcel.2004.05.011
    • (2004) Mol Cell , vol.14 , pp. 553-557
    • Bourbon, H.M.1    Aguilera, A.2    Ansari, A.Z.3    Asturias, F.J.4    Berk, A.J.5    Bjorklund, S.6
  • 15
    • 47249134314 scopus 로고    scopus 로고
    • Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
    • PMID:18515835
    • Bourbon HM. Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex. Nucleic Acids Res 2008; 36:3993-4008; PMID:18515835; http://dx.doi.org/10.1093/nar/gkn349
    • (2008) Nucleic Acids Res , vol.36 , pp. 3993-4008
    • Bourbon, H.M.1
  • 16
    • 79952255182 scopus 로고    scopus 로고
    • CDK8: A positive regulator of transcription
    • PMID:21327159
    • Galbraith MD, Donner AJ, Espinosa JM. CDK8: a positive regulator of transcription. Transcription 2010; 1:4-12; PMID:21327159; http://dx.doi.org/10. 4161/trns.1.1.12373
    • (2010) Transcription , vol.1 , pp. 4-112
    • Galbraith, M.D.1    Donner, A.J.2    Espinosa, J.M.3
  • 17
    • 80054949798 scopus 로고    scopus 로고
    • Dysregulation of CDK8 and Cyclin C in tumorigenesis
    • PMID:22035865
    • Xu W, Ji JY. Dysregulation of CDK8 and Cyclin C in tumorigenesis. J Genet Genomics 2011; 38:439-52; PMID:22035865; http://dx.doi.org/10.1016/j.jgg.2011. 09.002
    • (2011) J Genet Genomics , vol.38 , pp. 439-452
    • Xu, W.1    Ji, J.Y.2
  • 18
    • 33644547983 scopus 로고    scopus 로고
    • Relationship of gene expression and chromosomal abnormalities in colorectal cancer
    • PMID:16489013
    • Tsafrir D, Bacolod M, Selvanayagam Z, Tsafrir I, Shia J, Zeng Z, et al. Relationship of gene expression and chromosomal abnormalities in colorectal cancer. Cancer Res 2006; 66:2129-37; PMID:16489013; http://dx.doi.org/10.1158/ 0008-5472.CAN-05-2569
    • (2006) Cancer Res , vol.66 , pp. 2129-2137
    • Tsafrir, D.1    Bacolod, M.2    Selvanayagam, Z.3    Tsafrir, I.4    Shia, J.5    Zeng, Z.6
  • 19
    • 36348970735 scopus 로고    scopus 로고
    • Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types
    • PMID:18006816
    • Martin ES, Tonon G, Sinha R, Xiao Y, Feng B, Kimmelman AC, et al. Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types. Cancer Res 2007; 67:10736-43; PMID:18006816; http://dx.doi.org/10.1158/ 0008-5472.CAN-07-2742
    • (2007) Cancer Res , vol.67 , pp. 10736-10743
    • Martin, E.S.1    Tonon, G.2    Sinha, R.3    Xiao, Y.4    Feng, B.5    Kimmelman, A.C.6
  • 20
    • 66349121667 scopus 로고    scopus 로고
    • Association of survival and disease progression with chromosomal instability: A genomic exploration of colorectal cancer
    • PMID:19359472
    • Sheffer M, Bacolod MD, Zuk O, Giardina SF, Pincas H, Barany F, et al. Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer. Proc Natl Acad Sci USA 2009; 106:7131-6; PMID:19359472; http://dx.doi.org/10.1073/pnas.0902232106
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7131-7136
    • Sheffer, M.1    Bacolod, M.D.2    Zuk, O.3    Giardina, S.F.4    Pincas, H.5    Barany, F.6
  • 21
    • 77952977350 scopus 로고    scopus 로고
    • Role of CDK8 and betacatenin in colorectal adenocarcinoma
    • PMID:20514474
    • Seo JO, Han SI, Lim SC. Role of CDK8 and betacatenin in colorectal adenocarcinoma. Oncol Rep 2010; 24:285-91; PMID:20514474
    • (2010) Oncol Rep , vol.24 , pp. 285-291
    • Seo, J.O.1    Han, S.I.2    Lim, S.C.3
  • 22
    • 79955034418 scopus 로고    scopus 로고
    • Roles of cyclin-dependent kinase 8 and β-catenin in the oncogenesis and progression of gastric adenocarcinoma
    • PMID:21344156
    • Kim MY, Han SI, Lim SC. Roles of cyclin-dependent kinase 8 and β-catenin in the oncogenesis and progression of gastric adenocarcinoma. Int J Oncol 2011; 38:1375-83; PMID:21344156
    • (2011) Int J Oncol , vol.38 , pp. 1375-1383
    • Kim, M.Y.1    Han, S.I.2    Lim, S.C.3
  • 23
    • 77951910398 scopus 로고    scopus 로고
    • CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival
    • PMID:19790197
    • Firestein R, Shima K, Nosho K, Irahara N, Baba Y, Bojarski E, et al. CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival. Int J Cancer 2010; 126:2863-73; PMID:19790197
    • (2010) Int J Cancer , vol.126 , pp. 2863-2873
    • Firestein, R.1    Shima, K.2    Nosho, K.3    Irahara, N.4    Baba, Y.5    Bojarski, E.6
  • 24
    • 80054920976 scopus 로고    scopus 로고
    • Interplay between cyclin-dependent kinases and e2f-dependent transcription
    • Enders G, ed. Cell Cycle Deregulation in Cancer: Springer
    • Ji JY, Dyson NJ. Interplay between Cyclin-dependent Kinases and E2F-dependent Transcription. In: Enders G, ed. Cell Cycle Deregulation in Cancer: Springer Science 2010:23-41
    • (2010) Science , pp. 23-41
    • Ji, J.Y.1    Dyson, N.J.2
  • 25
    • 78650271810 scopus 로고    scopus 로고
    • The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8
    • PMID:21067790
    • Brewster CD, Birkenheuer CH, Vogt MB, Quackenbush SL, Rovnak J. The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8. Virology 2011; 409:299-307; PMID:21067790; http://dx.doi.org/10.1016/ j.virol.2010.10.022
    • (2011) Virology , vol.409 , pp. 299-307
    • Brewster, C.D.1    Birkenheuer, C.H.2    Vogt, M.B.3    Quackenbush, S.L.4    Rovnak, J.5
  • 26
    • 84861325132 scopus 로고    scopus 로고
    • Retroviral cyclin enhances cyclin-dependent kinase-8 activity
    • PMID:22379099
    • Rovnak J, Brewster CD, Quackenbush SL. Retroviral cyclin enhances cyclin-dependent kinase-8 activity. J Virol 2012; 86:5742-51; PMID:22379099; http://dx.doi.org/10.1128/JVI.07006-11
    • (2012) J Virol , vol.86 , pp. 5742-5751
    • Rovnak, J.1    Brewster, C.D.2    Quackenbush, S.L.3
  • 27
    • 77249119762 scopus 로고    scopus 로고
    • The landscape of somatic copy-number alteration across human cancers
    • PMID:20164920
    • Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010; 463:899-905; PMID:20164920; http://dx.doi.org/10.1038/nature08822
    • (2010) Nature , vol.463 , pp. 899-905
    • Beroukhim, R.1    Mermel, C.H.2    Porter, D.3    Wei, G.4    Raychaudhuri, S.5    Donovan, J.6
  • 28
    • 77249109757 scopus 로고    scopus 로고
    • Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India
    • PMID:20083228
    • Chattopadhyay I, Singh A, Phukan R, Purkayastha J, Kataki A, Mahanta J, et al. Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India. Mutat Res 2010; 696:130-8; PMID:20083228; http://dx.doi.org/10.1016/j.mrgentox.2010.01.001
    • (2010) Mutat Res , vol.696 , pp. 130-138
    • Chattopadhyay, I.1    Singh, A.2    Phukan, R.3    Purkayastha, J.4    Kataki, A.5    Mahanta, J.6
  • 29
    • 33747585109 scopus 로고    scopus 로고
    • The use of genetic programming in the analysis of quantitative gene expression profiles for identification of nodal status in bladder cancer
    • PMID:16780590
    • Mitra AP, Almal AA, George B, Fry DW, Lenehan PF, Pagliarulo V, et al. The use of genetic programming in the analysis of quantitative gene expression profiles for identification of nodal status in bladder cancer. BMC Cancer 2006; 6:159; PMID:16780590; http://dx.doi.org/10.1186/1471-2407-6-159
    • (2006) BMC Cancer , vol.6 , pp. 159
    • Mitra, A.P.1    Almal, A.A.2    George, B.3    Fry, D.W.4    Lenehan, P.F.5    Pagliarulo, V.6
  • 30
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • PMID:17344846
    • Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, et al. Patterns of somatic mutation in human cancer genomes. Nature 2007; 446:153-8; PMID:17344846; http://dx.doi.org/10.1038/nature05610
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1    Stephens, P.2    Smith, R.3    Dalgliesh, G.L.4    Hunter, C.5    Bignell, G.6
  • 31
    • 84863552454 scopus 로고    scopus 로고
    • Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1
    • PMID:22684109
    • Zhao X, Feng D, Wang Q, Abdulla A, Xie XJ, Zhou J, et al. Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest 2012; 122:2417-27; PMID:22684109; http://dx.doi.org/10.1172/JCI61462
    • (2012) J Clin Invest , vol.122 , pp. 2417-2427
    • Zhao, X.1    Feng, D.2    Wang, Q.3    Abdulla, A.4    Xie, X.J.5    Zhou, J.6
  • 33
    • 0030710144 scopus 로고    scopus 로고
    • Diet, body size, physical activity, and the risk of endometrial cancer
    • PMID:9371506
    • Goodman MT, Hankin JH, Wilkens LR, Lyu LC, McDuffie K, Liu LQ, et al. Diet, body size, physical activity, and the risk of endometrial cancer. Cancer Res 1997; 57:5077-85; PMID:9371506
    • (1997) Cancer Res , vol.57 , pp. 5077-5085
    • Goodman, M.T.1    Hankin, J.H.2    Wilkens, L.R.3    Lyu, L.C.4    McDuffie, K.5    Liu, L.Q.6
  • 34
    • 33748703827 scopus 로고    scopus 로고
    • Obesity and cancer risk: The role of the insulin-IGF axis
    • PMID:16956771
    • Renehan AG, Frystyk J, Flyvbjerg A. Obesity and cancer risk: the role of the insulin-IGF axis. Trends Endocrinol Metab 2006; 17:328-36; PMID:16956771; http://dx.doi.org/10.1016/j.tem.2006.08.006
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 328-336
    • Renehan, A.G.1    Frystyk, J.2    Flyvbjerg, A.3
  • 35
    • 32144441470 scopus 로고    scopus 로고
    • Commentary: Weight gain, weight loss, and endometrial cancer
    • PMID:16394116
    • Webb PM. Commentary: weight gain, weight loss, and endometrial cancer. Int J Epidemiol 2006; 35:166-8; PMID:16394116; http://dx.doi.org/10.1093/ije/ dyi301
    • (2006) Int J Epidemiol , vol.35 , pp. 166-168
    • Webb, P.M.1
  • 36
    • 52949093102 scopus 로고    scopus 로고
    • E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8
    • PMID:18794899
    • Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, et al. E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature 2008; 455:552-6; PMID:18794899; http://dx.doi.org/10.1038/nature07310
    • (2008) Nature , vol.455 , pp. 552-556
    • Morris, E.J.1    Ji, J.Y.2    Yang, F.3    Di Stefano, L.4    Herr, A.5    Moon, N.S.6
  • 37
    • 84880923558 scopus 로고    scopus 로고
    • CDK8 regulates E2F1 transcriptional activity through S375 phosphorylation
    • PMID:22945643
    • Zhao J, Ramos R, Demma M. CDK8 regulates E2F1 transcriptional activity through S375 phosphorylation. Oncogene 2012; PMID:22945643; http://dx.doi.org/ 10.1038/onc.2012.364
    • (2012) Oncogene
    • Zhao, J.1    Ramos, R.2    Demma, M.3
  • 38
    • 84860159915 scopus 로고    scopus 로고
    • CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency
    • PMID:22345154
    • Adler AS, McCleland ML, Truong T, Lau S, Modrusan Z, Soukup TM, et al. CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency. Cancer Res 2012; 72:2129-39; PMID:22345154; http://dx.doi.org/10.1158/0008-5472. CAN-11-3886
    • (2012) Cancer Res , vol.72 , pp. 2129-2139
    • Adler, A.S.1    McCleland, M.L.2    Truong, T.3    Lau, S.4    Modrusan, Z.5    Soukup, T.M.6
  • 39
    • 0035336896 scopus 로고    scopus 로고
    • Transcriptional activation: Risky business
    • PMID:11331599
    • Tansey WP. Transcriptional activation: risky business. Genes Dev 2001; 15:1045-50; PMID:11331599; http://dx.doi.org/10.1101/gad.896501
    • (2001) Genes Dev , vol.15 , pp. 1045-1050
    • Tansey, W.P.1
  • 40
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • PMID:11994399
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109:1125-31; PMID:11994399
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 41
    • 39849102805 scopus 로고    scopus 로고
    • Regulation of sterol synthesis in eukaryotes
    • PMID:17666007
    • Espenshade PJ, Hughes AL. Regulation of sterol synthesis in eukaryotes. Annu Rev Genet 2007; 41:401-27; PMID:17666007; http://dx.doi.org/10.1146/ annurev.genet.41.110306.130315
    • (2007) Annu Rev Genet , vol.41 , pp. 401-427
    • Espenshade, P.J.1    Hughes, A.L.2
  • 42
    • 0037082099 scopus 로고    scopus 로고
    • Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis
    • PMID:11795864
    • Goldstein JL, Rawson RB, Brown MS. Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis. Arch Biochem Biophys 2002; 397:139-48; PMID:11795864; http://dx.doi.org/10.1006/abbi.2001.2615
    • (2002) Arch Biochem Biophys , vol.397 , pp. 139-148
    • Goldstein, J.L.1    Rawson, R.B.2    Brown, M.S.3
  • 43
    • 39849083646 scopus 로고    scopus 로고
    • SREBPs: The crossroads of physiological and pathological lipid homeostasis
    • PMID:18291668
    • Raghow R, Yellaturu C, Deng X, Park EA, Elam MB. SREBPs: the crossroads of physiological and pathological lipid homeostasis. Trends Endocrinol Metab 2008; 19:65-73; PMID:18291668; http://dx.doi.org/10.1016/j.tem.2007.10.009
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 65-73
    • Raghow, R.1    Yellaturu, C.2    Deng, X.3    Park, E.A.4    Elam, M.B.5
  • 44
    • 34748912615 scopus 로고    scopus 로고
    • Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
    • PMID:17882277
    • Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 2007; 7:763-77; PMID:17882277; http://dx.doi.org/10.1038/nrc2222
    • (2007) Nat Rev Cancer , vol.7 , pp. 763-777
    • Menendez, J.A.1    Lupu, R.2
  • 45
    • 44349096768 scopus 로고    scopus 로고
    • Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3
    • PMID:18418385
    • Meyer KD, Donner AJ, Knuesel MT, York AG, Espinosa JM, Taatjes DJ. Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. EMBO J 2008; 27:1447-57; PMID:18418385
    • (2008) EMBO J , vol.27 , pp. 1447-1457
    • Meyer, K.D.1    Donner, A.J.2    Knuesel, M.T.3    York, A.G.4    Espinosa, J.M.5    Taatjes, D.J.6
  • 46
    • 59249093974 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator
    • PMID:19047373
    • Knuesel MT, Meyer KD, Donner AJ, Espinosa JM, Taatjes DJ. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Mol Cell Biol 2009; 29:650-61; PMID:19047373; http://dx.doi.org/10.1128/MCB.00993-08
    • (2009) Mol Cell Biol , vol.29 , pp. 650-661
    • Knuesel, M.T.1    Meyer, K.D.2    Donner, A.J.3    Espinosa, J.M.4    Taatjes, D.J.5
  • 47
    • 61449143491 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
    • PMID:19240132
    • Knuesel MT, Meyer KD, Bernecky C, Taatjes DJ. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes Dev 2009; 23:439-51; PMID:19240132; http://dx.doi.org/10.1101/gad.1767009
    • (2009) Genes Dev , vol.23 , pp. 439-451
    • Knuesel, M.T.1    Meyer, K.D.2    Bernecky, C.3    Taatjes, D.J.4
  • 48
    • 34250847654 scopus 로고    scopus 로고
    • CDK8 is a stimulus-specific positive coregulator of p53 target genes
    • PMID:17612495
    • Donner AJ, Szostek S, Hoover JM, Espinosa JM. CDK8 is a stimulus-specific positive coregulator of p53 target genes. Mol Cell 2007; 27:121-33; PMID:17612495; http://dx.doi.org/10.1016/j.molcel.2007.05.026
    • (2007) Mol Cell , vol.27 , pp. 121-133
    • Donner, A.J.1    Szostek, S.2    Hoover, J.M.3    Espinosa, J.M.4
  • 49
    • 70350780570 scopus 로고    scopus 로고
    • Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways
    • PMID:19914168
    • Alarcón C, Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, et al. Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell 2009; 139:757-69; PMID:19914168; http://dx.doi.org/10. 1016/j.cell.2009.09.035
    • (2009) Cell , vol.139 , pp. 757-769
    • Alarcón, C.1    Zaromytidou, A.I.2    Xi, Q.3    Gao, S.4    Yu, J.5    Fujisawa, S.6
  • 50
    • 8844229536 scopus 로고    scopus 로고
    • Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
    • PMID:15546612
    • Fryer CJ, White JB, Jones KA. Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell 2004; 16:509-20; PMID:15546612; http://dx.doi.org/10.1016/j.molcel.2004.10.014
    • (2004) Mol Cell , vol.16 , pp. 509-520
    • Fryer, C.J.1    White, J.B.2    Jones, K.A.3
  • 51
    • 79957974446 scopus 로고    scopus 로고
    • Wnt/β-catenin and sex hormone signaling in endometrial homeostasis and cancer
    • PMID:21317462
    • Wang Y, van der Zee M, Fodde R, Blok LJ. Wnt/β-catenin and sex hormone signaling in endometrial homeostasis and cancer. Oncotarget 2010; 1:674-84; PMID:21317462
    • (2010) Oncotarget , vol.1 , pp. 674-684
    • Wang, Y.1    Van Der Zee, M.2    Fodde, R.3    Blok, L.J.4
  • 52
    • 0035052916 scopus 로고    scopus 로고
    • Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1
    • PMID:11287611
    • Wang C, Fu M, D'Amico M, Albanese C, Zhou JN, Brownlee M, et al. Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. Mol Cell Biol 2001; 21:3057-70; PMID:11287611; http://dx.doi.org/10.1128/ MCB.21.9.3057-3070.2001
    • (2001) Mol Cell Biol , vol.21 , pp. 3057-3070
    • Wang, C.1    Fu, M.2    D'Amico, M.3    Albanese, C.4    Zhou, J.N.5    Brownlee, M.6
  • 53
    • 78650045754 scopus 로고    scopus 로고
    • Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1
    • PMID:20956529
    • Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, et al. Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. J Biol Chem 2010; 285:40342-50; PMID:20956529; http://dx.doi.org/10.1074/jbc.M110.156141
    • (2010) J Biol Chem , vol.285 , pp. 40342-40350
    • Zhou, J.1    Liu, Y.2    Zhang, W.3    Popov, V.M.4    Wang, M.5    Pattabiraman, N.6


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