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Volumn 182, Issue 4, 2013, Pages 1322-1336

CD44 deficiency contributes to enhanced experimental autoimmune encephalomyelitis: A role in immune cells and vascular cells of the blood-brain barrier

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COMPLEMENTARY DNA; CYTOKINE; HERMES ANTIGEN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; RNA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

EID: 84875190575     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.01.003     Document Type: Article
Times cited : (50)

References (69)
  • 1
    • 33745728404 scopus 로고    scopus 로고
    • How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis
    • L. Steinman, and S.S. Zamvil How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis Ann Neurol 60 2006 12 21
    • (2006) Ann Neurol , vol.60 , pp. 12-21
    • Steinman, L.1    Zamvil, S.S.2
  • 2
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • J. Goverman Autoimmune T cell responses in the central nervous system Nat Rev Immunol 9 2009 393 407
    • (2009) Nat Rev Immunol , vol.9 , pp. 393-407
    • Goverman, J.1
  • 3
    • 0038643518 scopus 로고    scopus 로고
    • Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice
    • A.R. Oliver, G.M. Lyon, and N.H. Ruddle Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice J Immunol 171 2003 462 468
    • (2003) J Immunol , vol.171 , pp. 462-468
    • Oliver, A.R.1    Lyon, G.M.2    Ruddle, N.H.3
  • 7
    • 67649383126 scopus 로고    scopus 로고
    • Th17 cells in MS and experimental autoimmune encephalomyelitis
    • H. Hofstetter, R. Gold, and H.P. Hartung Th17 cells in MS and experimental autoimmune encephalomyelitis Int MS J 16 2009 12 18
    • (2009) Int MS J , vol.16 , pp. 12-18
    • Hofstetter, H.1    Gold, R.2    Hartung, H.P.3
  • 8
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • E. Bettelli, Y. Carrier, W. Gao, T. Korn, T.B. Strom, M. Oukka, H.L. Weiner, and V.K. Kuchroo Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 441 2006 235 238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 12
    • 23844478869 scopus 로고    scopus 로고
    • Natural recovery and protection from autoimmune encephalomyelitis: Contribution of CD4+CD25+ regulatory cells within the central nervous system
    • M.J. McGeachy, L.A. Stephens, and S.M. Anderton Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system J Immunol 175 2005 3025 3032
    • (2005) J Immunol , vol.175 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 13
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • W. Chen, W. Jin, N. Hardegen, K.J. Lei, L. Li, N. Marinos, G. McGrady, and S.M. Wahl Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3 J Exp Med 198 2003 1875 1886
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 14
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • J.A. Bluestone, and A.K. Abbas Natural versus adaptive regulatory T cells Nat Rev Immunol 3 2003 253 257
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 16
    • 0344961161 scopus 로고    scopus 로고
    • Blood-brain barrier disruption in multiple sclerosis
    • A. Minagar, and J.S. Alexander Blood-brain barrier disruption in multiple sclerosis Mult Scler 9 2003 540 549
    • (2003) Mult Scler , vol.9 , pp. 540-549
    • Minagar, A.1    Alexander, J.S.2
  • 17
    • 0842280615 scopus 로고    scopus 로고
    • The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events
    • R.F. Thorne, J.W. Legg, and C.M. Isacke The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events J Cell Sci 117 2004 373 380
    • (2004) J Cell Sci , vol.117 , pp. 373-380
    • Thorne, R.F.1    Legg, J.W.2    Isacke, C.M.3
  • 18
    • 0037227965 scopus 로고    scopus 로고
    • CD44: From adhesion molecules to signalling regulators
    • H. Ponta, L. Sherman, and P.A. Herrlich CD44: from adhesion molecules to signalling regulators Nat Rev Mol Cell Biol 4 2003 33 45
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 19
    • 0030690228 scopus 로고    scopus 로고
    • Requirement for CD44 in activated T cell extravasation into an inflammatory site
    • H.C. DeGrendele, P. Estess, and M.H. Siegelman Requirement for CD44 in activated T cell extravasation into an inflammatory site Science 278 1997 672 675
    • (1997) Science , vol.278 , pp. 672-675
    • Degrendele, H.C.1    Estess, P.2    Siegelman, M.H.3
  • 21
    • 0029002861 scopus 로고
    • Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis
    • K. Mikecz, F.R. Brennan, J.H. Kim, and T.T. Glant Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis Nat Med 1 1995 558 563
    • (1995) Nat Med , vol.1 , pp. 558-563
    • Mikecz, K.1    Brennan, F.R.2    Kim, J.H.3    Glant, T.T.4
  • 24
    • 0033535952 scopus 로고    scopus 로고
    • Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment
    • S. Brocke, C. Piercy, L. Steinman, I.L. Weissman, and T. Veromaa Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment Proc Natl Acad Sci U S A 96 1999 6896 6901
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6896-6901
    • Brocke, S.1    Piercy, C.2    Steinman, L.3    Weissman, I.L.4    Veromaa, T.5
  • 26
    • 0036900002 scopus 로고    scopus 로고
    • CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice
    • Q. Wang, P. Teder, N.P. Judd, P.W. Noble, and C.M. Doerschuk CD44 deficiency leads to enhanced neutrophil migration and lung injury in Escherichia coli pneumonia in mice Am J Pathol 161 2002 2219 2228
    • (2002) Am J Pathol , vol.161 , pp. 2219-2228
    • Wang, Q.1    Teder, P.2    Judd, N.P.3    Noble, P.W.4    Doerschuk, C.M.5
  • 27
    • 33846931099 scopus 로고    scopus 로고
    • CD44 is a negative regulator of acute pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages
    • J. Liang, D. Jiang, J. Griffith, S. Yu, J. Fan, X. Zhao, R. Bucala, and P.W. Noble CD44 is a negative regulator of acute pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages J Immunol 178 2007 2469 2475
    • (2007) J Immunol , vol.178 , pp. 2469-2475
    • Liang, J.1    Jiang, D.2    Griffith, J.3    Yu, S.4    Fan, J.5    Zhao, X.6    Bucala, R.7    Noble, P.W.8
  • 28
    • 73449119607 scopus 로고    scopus 로고
    • CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages
    • G.J. van der Windt, C. van 't Veer, S. Florquin, and T. van der Poll CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages Infect Immun 78 2010 115 124
    • (2010) Infect Immun , vol.78 , pp. 115-124
    • Van Der Windt, G.J.1    Van 'T Veer, C.2    Florquin, S.3    Van Der Poll, T.4
  • 29
    • 70450224883 scopus 로고    scopus 로고
    • Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS
    • J. Muto, K. Yamasaki, K.R. Taylor, and R.L. Gallo Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS Mol Immunol 47 2009 449 456
    • (2009) Mol Immunol , vol.47 , pp. 449-456
    • Muto, J.1    Yamasaki, K.2    Taylor, K.R.3    Gallo, R.L.4
  • 31
    • 11144304062 scopus 로고    scopus 로고
    • Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage
    • R.J. McKallip, M. Fisher, U. Gunthert, A.K. Szakal, P.S. Nagarkatti, and M. Nagarkatti Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: cD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage Infect Immun 73 2005 50 61
    • (2005) Infect Immun , vol.73 , pp. 50-61
    • McKallip, R.J.1    Fisher, M.2    Gunthert, U.3    Szakal, A.K.4    Nagarkatti, P.S.5    Nagarkatti, M.6
  • 33
    • 58149382597 scopus 로고    scopus 로고
    • CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis
    • G. Hutas, E. Bajnok, I. Gal, A. Finnegan, T.T. Glant, and K. Mikecz CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis Blood 112 2008 4999 5006
    • (2008) Blood , vol.112 , pp. 4999-5006
    • Hutas, G.1    Bajnok, E.2    Gal, I.3    Finnegan, A.4    Glant, T.T.5    Mikecz, K.6
  • 34
    • 0026069908 scopus 로고
    • Localization of the CD44 glycoprotein to fibrous astrocytes in normal white matter and to reactive astrocytes in active lesions in multiple sclerosis
    • N. Girgrah, M. Letarte, L.E. Becker, T.F. Cruz, E. Theriault, and M.A. Moscarello Localization of the CD44 glycoprotein to fibrous astrocytes in normal white matter and to reactive astrocytes in active lesions in multiple sclerosis J Neuropathol Exp Neurol 50 1991 779 792
    • (1991) J Neuropathol Exp Neurol , vol.50 , pp. 779-792
    • Girgrah, N.1    Letarte, M.2    Becker, L.E.3    Cruz, T.F.4    Theriault, E.5    Moscarello, M.A.6
  • 36
    • 0036154205 scopus 로고    scopus 로고
    • CD44-mediated uptake and degradation of hyaluronan
    • W. Knudson, G. Chow, and C.B. Knudson CD44-mediated uptake and degradation of hyaluronan Matrix Biol 21 2002 15 23
    • (2002) Matrix Biol , vol.21 , pp. 15-23
    • Knudson, W.1    Chow, G.2    Knudson, C.B.3
  • 37
    • 0036154206 scopus 로고    scopus 로고
    • Hyaluronan and its catabolic products in tissue injury and repair
    • P.W. Noble Hyaluronan and its catabolic products in tissue injury and repair Matrix Biol 21 2002 25 29
    • (2002) Matrix Biol , vol.21 , pp. 25-29
    • Noble, P.W.1
  • 38
    • 0030971397 scopus 로고    scopus 로고
    • Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptus
    • E. Pinter, M. Barreuther, T. Lu, B.A. Imhof, and J.A. Madri Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptus Am J Pathol 150 1997 1523 1530
    • (1997) Am J Pathol , vol.150 , pp. 1523-1530
    • Pinter, E.1    Barreuther, M.2    Lu, T.3    Imhof, B.A.4    Madri, J.A.5
  • 39
    • 34248673126 scopus 로고    scopus 로고
    • Isolation of murine microglial cells for RNA analysis or flow cytometry
    • A.E. Cardona, D. Huang, M.E. Sasse, and R.M. Ransohoff Isolation of murine microglial cells for RNA analysis or flow cytometry Nat Protoc 1 2006 1947 1951
    • (2006) Nat Protoc , vol.1 , pp. 1947-1951
    • Cardona, A.E.1    Huang, D.2    Sasse, M.E.3    Ransohoff, R.M.4
  • 40
    • 0031596366 scopus 로고    scopus 로고
    • The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis
    • D. Graesser, S. Mahooti, T. Haas, S. Davis, R.B. Clark, and J.A. Madri The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis Lab Invest 78 1998 1445 1458
    • (1998) Lab Invest , vol.78 , pp. 1445-1458
    • Graesser, D.1    Mahooti, S.2    Haas, T.3    Davis, S.4    Clark, R.B.5    Madri, J.A.6
  • 42
    • 79959536193 scopus 로고    scopus 로고
    • CD44 reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis
    • H. Guan, P.S. Nagarkatti, and M. Nagarkatti CD44 reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis J Immunol 186 2011 6955 6964
    • (2011) J Immunol , vol.186 , pp. 6955-6964
    • Guan, H.1    Nagarkatti, P.S.2    Nagarkatti, M.3
  • 44
    • 0034685935 scopus 로고    scopus 로고
    • Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44
    • A. Nandi, P. Estess, and M.H. Siegelman Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44 J Biol Chem 275 2000 14939 14948
    • (2000) J Biol Chem , vol.275 , pp. 14939-14948
    • Nandi, A.1    Estess, P.2    Siegelman, M.H.3
  • 46
    • 48449086316 scopus 로고    scopus 로고
    • TGF-beta: A master of all T cell trades
    • M.O. Li, and R.A. Flavell TGF-beta: a master of all T cell trades Cell 134 2008 392 404
    • (2008) Cell , vol.134 , pp. 392-404
    • Li, M.O.1    Flavell, R.A.2
  • 47
    • 68849126246 scopus 로고    scopus 로고
    • Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity
    • S. Sanjabi, L.A. Zenewicz, M. Kamanaka, and R.A. Flavell Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity Curr Opin Pharmacol 9 2009 447 453
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 447-453
    • Sanjabi, S.1    Zenewicz, L.A.2    Kamanaka, M.3    Flavell, R.A.4
  • 48
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • E.M. Shevach Mechanisms of foxp3+ T regulatory cell-mediated suppression Immunity 30 2009 636 645
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 49
    • 37849027594 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease
    • R.A. O'Connor, and S.M. Anderton Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease J Neuroimmunol 193 2008 1 11
    • (2008) J Neuroimmunol , vol.193 , pp. 1-11
    • O'Connor, R.A.1    Anderton, S.M.2
  • 50
    • 30444458396 scopus 로고    scopus 로고
    • Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44
    • M. Firan, S. Dhillon, P. Estess, and M.H. Siegelman Suppressor activity and potency among regulatory T cells is discriminated by functionally active CD44 Blood 107 2006 619 627
    • (2006) Blood , vol.107 , pp. 619-627
    • Firan, M.1    Dhillon, S.2    Estess, P.3    Siegelman, M.H.4
  • 52
    • 72149124496 scopus 로고    scopus 로고
    • Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation
    • G.J. Martinez, Z. Zhang, Y. Chung, J.M. Reynolds, X. Lin, A.M. Jetten, X.H. Feng, and C. Dong Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation J Biol Chem 284 2009 35283 35286
    • (2009) J Biol Chem , vol.284 , pp. 35283-35286
    • Martinez, G.J.1    Zhang, Z.2    Chung, Y.3    Reynolds, J.M.4    Lin, X.5    Jetten, A.M.6    Feng, X.H.7    Dong, C.8
  • 54
    • 80051626171 scopus 로고    scopus 로고
    • 4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T Cells
    • Y.H. Kim, B.K. Choi, S.M. Shin, C.H. Kim, H.S. Oh, S.H. Park, D.G. Lee, M.J. Lee, K.H. Kim, D.S. Vinay, and B.S. Kwon 4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T Cells J Immunol 187 2011 1120 1128
    • (2011) J Immunol , vol.187 , pp. 1120-1128
    • Kim, Y.H.1    Choi, B.K.2    Shin, S.M.3    Kim, C.H.4    Oh, H.S.5    Park, S.H.6    Lee, D.G.7    Lee, M.J.8    Kim, K.H.9    Vinay, D.S.10    Kwon, B.S.11
  • 55
    • 79251584980 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells
    • E. Beurel, W.I. Yeh, S.M. Michalek, L.E. Harrington, and R.S. Jope Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells J Immunol 186 2011 1391 1398
    • (2011) J Immunol , vol.186 , pp. 1391-1398
    • Beurel, E.1    Yeh, W.I.2    Michalek, S.M.3    Harrington, L.E.4    Jope, R.S.5
  • 56
    • 38149054804 scopus 로고    scopus 로고
    • Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling
    • X. Guo, A. Ramirez, D.S. Waddell, Z. Li, X. Liu, and X.F. Wang Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling Genes Dev 22 2008 106 120
    • (2008) Genes Dev , vol.22 , pp. 106-120
    • Guo, X.1    Ramirez, A.2    Waddell, D.S.3    Li, Z.4    Liu, X.5    Wang, X.F.6
  • 58
    • 58149239730 scopus 로고    scopus 로고
    • Phospho-control of TGF-beta superfamily signaling
    • K.H. Wrighton, X. Lin, and X.H. Feng Phospho-control of TGF-beta superfamily signaling Cell Res 19 2009 8 20
    • (2009) Cell Res , vol.19 , pp. 8-20
    • Wrighton, K.H.1    Lin, X.2    Feng, X.H.3
  • 59
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • M. Martin, K. Rehani, R.S. Jope, and S.M. Michalek Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3 Nat Immunol 6 2005 777 784
    • (2005) Nat Immunol , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3    Michalek, S.M.4
  • 60
    • 0037131169 scopus 로고    scopus 로고
    • Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor i in metastatic breast tumor cells
    • L.Y. Bourguignon, P.A. Singleton, H. Zhu, and B. Zhou Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells J Biol Chem 277 2002 39703 39712
    • (2002) J Biol Chem , vol.277 , pp. 39703-39712
    • Bourguignon, L.Y.1    Singleton, P.A.2    Zhu, H.3    Zhou, B.4
  • 61
    • 68349154367 scopus 로고    scopus 로고
    • Viscoelastic response of a model endothelial glycocalyx
    • N. Nijenhuis, D. Mizuno, J.A. Spaan, and C.F. Schmidt Viscoelastic response of a model endothelial glycocalyx Phys Biol 6 2009 025014
    • (2009) Phys Biol , vol.6 , pp. 025014
    • Nijenhuis, N.1    Mizuno, D.2    Spaan, J.A.3    Schmidt, C.F.4
  • 62
    • 0030917306 scopus 로고    scopus 로고
    • Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation
    • G. Kaya, I. Rodriguez, J.L. Jorcano, P. Vassalli, and I. Stamenkovic Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation Genes Dev 11 1997 996 1007
    • (1997) Genes Dev , vol.11 , pp. 996-1007
    • Kaya, G.1    Rodriguez, I.2    Jorcano, J.L.3    Vassalli, P.4    Stamenkovic, I.5
  • 64
    • 0033768928 scopus 로고    scopus 로고
    • Cell migration in the immune system: The evolving inter-related roles of adhesion molecules and proteinases
    • J.A. Madri, and D. Graesser Cell migration in the immune system: the evolving inter-related roles of adhesion molecules and proteinases Dev Immunol 7 2000 103 116
    • (2000) Dev Immunol , vol.7 , pp. 103-116
    • Madri, J.A.1    Graesser, D.2
  • 65
    • 0032911086 scopus 로고    scopus 로고
    • Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells
    • K. Takahashi, H. Eto, and K.K. Tanabe Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells Int J Cancer 80 1999 387 395
    • (1999) Int J Cancer , vol.80 , pp. 387-395
    • Takahashi, K.1    Eto, H.2    Tanabe, K.K.3
  • 66
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
    • Q. Yu, and I. Stamenkovic Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis Genes Dev 14 2000 163 176
    • (2000) Genes Dev , vol.14 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2
  • 67
    • 79960741978 scopus 로고    scopus 로고
    • MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia
    • Y. Yang, and G.A. Rosenberg MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemia Methods Mol Biol 762 2011 333 345
    • (2011) Methods Mol Biol , vol.762 , pp. 333-345
    • Yang, Y.1    Rosenberg, G.A.2
  • 68
    • 7744231499 scopus 로고    scopus 로고
    • MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity
    • J. Esparza, M. Kruse, J. Lee, M. Michaud, and J.A. Madri MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity FASEB J 18 2004 1682 1691
    • (2004) FASEB J , vol.18 , pp. 1682-1691
    • Esparza, J.1    Kruse, M.2    Lee, J.3    Michaud, M.4    Madri, J.A.5
  • 69
    • 29244463365 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions at the blood-brain barrier
    • N.J. Abbott, L. Ronnback, and E. Hansson Astrocyte-endothelial interactions at the blood-brain barrier Nat Rev Neurosci 7 2006 41 53
    • (2006) Nat Rev Neurosci , vol.7 , pp. 41-53
    • Abbott, N.J.1    Ronnback, L.2    Hansson, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.