Co-expression of NaVβ subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins

British Journal of Pharmacology

Volumn 168, Issue 7, 2013, Pages 1597-1610

  Zhang, Min Min ^a   Wilson, Michael J ^a   Azam, Layla ^a   Gajewiak, Joanna ^a   Rivier, Jean E ^c   Bulaj, Grzegorz ^b   Olivera, Baldomero M ^a   Yoshikami, Doju ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

conotoxin KIIIA; conotoxin PIIIA; conotoxin SmIIIA; conotoxin TIIIA; NaV subunit; saxitoxin; site 1; tetrodotoxin; voltage gated sodium channel; Xenopus oocytes

Indexed keywords

CHIMERIC PROTEIN; CONOTOXIN; MU CONOTOXIN; SAXITOXIN; SODIUM CHANNEL NAV1.7; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL BETA 1 SUBUNIT; VOLTAGE GATED SODIUM CHANNEL BETA 2 SUBUNIT; VOLTAGE GATED SODIUM CHANNEL BETA 3 SUBUNIT; VOLTAGE GATED SODIUM CHANNEL BETA 4 SUBUNIT; VOLTAGE GATED SODIUM CHANNEL BETA SUBUNIT;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CHANNEL GATING; CONTROLLED STUDY; INHIBITION KINETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; XENOPUS LAEVIS;

ANIMALS; CONOTOXINS; FEMALE; KINETICS; OOCYTES; PROTEIN ISOFORMS; RATS; SODIUM CHANNEL BLOCKERS; VOLTAGE-GATED SODIUM CHANNEL BETA SUBUNITS; VOLTAGE-GATED SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 84875156170     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12051     Document Type: Article

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