Navβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIB

Journal of Pharmacology and Experimental Therapeutics

Volumn 338, Issue 2, 2011, Pages 687-693

  Wilson, Michael J ^a   Zhang, Min Min ^a   Azam, Layla ^a   Olivera, Baldomero M ^a   Bulaj, Grzegorz ^a   Yoshikami, Doju ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA CONOTOXIN SVIB; PROTEIN SUBUNIT; SAXITOXIN; SODIUM CHANNEL NAV1.8; ANALGESIC AGENT; CONOTOXIN; MUO CONOTOXIN MRVIB; MUO-CONOTOXIN MRVIB; SENSORY NEURON SPECIFIC (SNS) SODIUM CHANNEL; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; BETA CHAIN; BINDING AFFINITY; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG EFFICACY; NERVE CELL; NERVE INJURY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; XENOPUS LAEVIS; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; METABOLISM; PEPTIDE SYNTHESIS; PHYSIOLOGY; PROTEIN BINDING; RAT;

ANALGESICS, NON-NARCOTIC; ANIMALS; CONOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; OOCYTES; PEPTIDE BIOSYNTHESIS; PROTEIN BINDING; PROTEIN SUBUNITS; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 79960552521     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.178343     Document Type: Article

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