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Volumn 169, Issue 1, 2013, Pages 102-114

Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins

Author keywords

conotoxin PIIIA; conotoxin SmIIIA; conotoxin TIIIA; dorsal root ganglion; superior cervical ganglion; tetrodotoxin; voltage gated sodium channel; whole cell patch clamp

Indexed keywords

CONOTOXIN; MU CONOTOXIN; MU CONOTOXIN PIIIA; MU CONOTOXIN SMIIIA; MU CONOTOXIN TIIIA; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL BETA SUBUNIT;

EID: 84875158614     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12119     Document Type: Article
Times cited : (26)

References (54)
  • 1
    • 0037382254 scopus 로고    scopus 로고
    • Electrical excitability of the soma of sensory neurons is required for spike invasion of the soma, but not for through-conduction
    • Amir R, Devor M, (2003). Electrical excitability of the soma of sensory neurons is required for spike invasion of the soma, but not for through-conduction. Biophys J 84: 2181-2191.
    • (2003) Biophys J , vol.84 , pp. 2181-2191
    • Amir, R.1    Devor, M.2
  • 3
    • 1542498432 scopus 로고    scopus 로고
    • Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain
    • Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG, (2004). Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain 108: 237-247.
    • (2004) Pain , vol.108 , pp. 237-247
    • Black, J.A.1    Liu, S.2    Tanaka, M.3    Cummins, T.R.4    Waxman, S.G.5
  • 4
    • 0036895970 scopus 로고    scopus 로고
    • Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons
    • Blair NT, Bean BP, (2002). Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons. J Neurosci 22: 10277-10290.
    • (2002) J Neurosci , vol.22 , pp. 10277-10290
    • Blair, N.T.1    Bean, B.P.2
  • 5
    • 84857211318 scopus 로고    scopus 로고
    • Na channel β subunits: Overachievers of the ion channel family
    • Brackenbury WJ, Isom LL, (2011). Na channel β subunits: overachievers of the ion channel family. Front Pharmacol 2: 53.
    • (2011) Front Pharmacol , vol.2 , pp. 53
    • Brackenbury, W.J.1    Isom, L.L.2
  • 6
    • 0032191372 scopus 로고    scopus 로고
    • Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea
    • Brock JA, McLachlan E, Belmonte C, (1998). Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea. J Physiol (Lond) 512 (Pt 1): 211-217.
    • (1998) J Physiol (Lond) , vol.512 , Issue.PART 1 , pp. 211-217
    • Brock, J.A.1    McLachlan, E.2    Belmonte, C.3
  • 7
    • 0026727782 scopus 로고
    • Three types of sodium channels in adult rat dorsal root ganglion neurons
    • Caffrey JM, Eng DL, Black JA, Waxman SG, Kocsis JD, (1992). Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 592: 283-297.
    • (1992) Brain Res , vol.592 , pp. 283-297
    • Caffrey, J.M.1    Eng, D.L.2    Black, J.A.3    Waxman, S.G.4    Kocsis, J.D.5
  • 9
    • 77956996917 scopus 로고    scopus 로고
    • Ion channel voltage sensors: Structure, function, and pathophysiology
    • Catterall WA, (2010). Ion channel voltage sensors: structure, function, and pathophysiology. Neuron 67: 915-928.
    • (2010) Neuron , vol.67 , pp. 915-928
    • Catterall, W.A.1
  • 10
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
    • Catterall WA, Goldin AL, Waxman SG, (2005). International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev 57: 397-409.
    • (2005) Pharmacol Rev , vol.57 , pp. 397-409
    • Catterall, W.A.1    Goldin, A.L.2    Waxman, S.G.3
  • 12
    • 84858203214 scopus 로고    scopus 로고
    • Regulatory role of voltage-gated Na channel β subunits in sensory neurons
    • Chahine M, O'Leary ME, (2011). Regulatory role of voltage-gated Na channel β subunits in sensory neurons. Front Pharmacol 2: 70.
    • (2011) Front Pharmacol , vol.2 , pp. 70
    • Chahine, M.1    O'Leary, M.E.2
  • 13
    • 33745737497 scopus 로고    scopus 로고
    • Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons
    • Choi JS, Hudmon A, Waxman SG, Dib-Hajj SD, (2006). Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. J Neurophysiol 96: 97-108.
    • (2006) J Neurophysiol , vol.96 , pp. 97-108
    • Choi, J.S.1    Hudmon, A.2    Waxman, S.G.3    Dib-Hajj, S.D.4
  • 14
    • 78049357954 scopus 로고    scopus 로고
    • Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; And alter sodium channel gating properties
    • Dib-Hajj SD, Waxman SG, (2010). Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties. Neurosci Lett 486: 84-91.
    • (2010) Neurosci Lett , vol.486 , pp. 84-91
    • Dib-Hajj, S.D.1    Waxman, S.G.2
  • 15
    • 0032723079 scopus 로고    scopus 로고
    • Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
    • Dib-Hajj SD, Fjell J, Cummins TR, Zheng Z, Fried K, LaMotte R, et al. (1999). Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 83: 591-600.
    • (1999) Pain , vol.83 , pp. 591-600
    • Dib-Hajj, S.D.1    Fjell, J.2    Cummins, T.R.3    Zheng, Z.4    Fried, K.5    Lamotte, R.6
  • 17
    • 52049087810 scopus 로고    scopus 로고
    • Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments
    • Duflocq A, Le Bras B, Bullier E, Couraud F, Davenne M, (2008). Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments. Mol Cell Neurosci 39: 180-192.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 180-192
    • Duflocq, A.1    Le Bras, B.2    Bullier, E.3    Couraud, F.4    Davenne, M.5
  • 18
    • 0027414377 scopus 로고
    • Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia
    • Elliott AA, Elliott JR, (1993). Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J Physiol (Lond) 463: 39-56.
    • (1993) J Physiol (Lond) , vol.463 , pp. 39-56
    • Elliott, A.A.1    Elliott, J.R.2
  • 19
    • 44249086114 scopus 로고    scopus 로고
    • Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7
    • Fiedler B, Zhang MM, Buczek O, Azam L, Bulaj G, Norton RS, et al. (2008). Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochem Pharmacol 75: 2334-2344.
    • (2008) Biochem Pharmacol , vol.75 , pp. 2334-2344
    • Fiedler, B.1    Zhang, M.M.2    Buczek, O.3    Azam, L.4    Bulaj, G.5    Norton, R.S.6
  • 20
    • 50249127742 scopus 로고    scopus 로고
    • Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
    • Fukuoka T, Kobayashi K, Yamanaka H, Obata K, Dai Y, Noguchi K, (2008). Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons. J Comp Neurol 510: 188-206.
    • (2008) J Comp Neurol , vol.510 , pp. 188-206
    • Fukuoka, T.1    Kobayashi, K.2    Yamanaka, H.3    Obata, K.4    Dai, Y.5    Noguchi, K.6
  • 22
    • 0021895384 scopus 로고
    • Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones
    • Harper AA, Lawson SN, (1985). Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones. J Physiol 359: 31-46.
    • (1985) J Physiol , vol.359 , pp. 31-46
    • Harper, A.A.1    Lawson, S.N.2
  • 23
    • 0141646635 scopus 로고    scopus 로고
    • Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons
    • Herzog RI, Cummins TR, Ghassemi F, Dib-Hajj SD, Waxman SG, (2003). Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons. J Physiol (Lond) 551 (Pt 3): 741-750.
    • (2003) J Physiol (Lond) , vol.551 , Issue.PART 3 , pp. 741-750
    • Herzog, R.I.1    Cummins, T.R.2    Ghassemi, F.3    Dib-Hajj, S.D.4    Waxman, S.G.5
  • 25
    • 78650870302 scopus 로고    scopus 로고
    • Single-cell analysis of sodium channel expression in dorsal root ganglion neurons
    • Ho C, O'Leary ME, (2011). Single-cell analysis of sodium channel expression in dorsal root ganglion neurons. Mol Cell Neurosci 46: 159-166.
    • (2011) Mol Cell Neurosci , vol.46 , pp. 159-166
    • Ho, C.1    O'Leary, M.E.2
  • 27
    • 79957868138 scopus 로고    scopus 로고
    • Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels
    • Leipold E, Markgraf R, Miloslavina A, Kijas M, Schirmeyer J, Imhof D, et al. (2011). Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels. Neuropharmacology 61: 105-111.
    • (2011) Neuropharmacology , vol.61 , pp. 105-111
    • Leipold, E.1    Markgraf, R.2    Miloslavina, A.3    Kijas, M.4    Schirmeyer, J.5    Imhof, D.6
  • 28
    • 33847158419 scopus 로고    scopus 로고
    • Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels
    • Lewis RJ, Schroeder CI, Ekberg J, Nielsen KJ, Loughnan M, Thomas L, et al. (2007). Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels. Mol Pharmacol 71: 676-685.
    • (2007) Mol Pharmacol , vol.71 , pp. 676-685
    • Lewis, R.J.1    Schroeder, C.I.2    Ekberg, J.3    Nielsen, K.J.4    Loughnan, M.5    Thomas, L.6
  • 30
    • 57349129522 scopus 로고    scopus 로고
    • Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1
    • Light AR, Hughen RW, Zhang J, Rainier J, Liu Z, Lee J, (2008). Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1. J Neurophysiol 100: 1184-1201.
    • (2008) J Neurophysiol , vol.100 , pp. 1184-1201
    • Light, A.R.1    Hughen, R.W.2    Zhang, J.3    Rainier, J.4    Liu, Z.5    Lee, J.6
  • 31
    • 84861881276 scopus 로고    scopus 로고
    • Modulation of neuronal sodium channels by the sea anemone peptide BDS-I
    • Liu P, Jo S, Bean BP, (2012). Modulation of neuronal sodium channels by the sea anemone peptide BDS-I. J Neurophysiol 107: 3155-3167.
    • (2012) J Neurophysiol , vol.107 , pp. 3155-3167
    • Liu, P.1    Jo, S.2    Bean, B.P.3
  • 32
    • 80053200238 scopus 로고    scopus 로고
    • Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA
    • McArthur JR, Singh G, McMaster D, Winkfein R, Tieleman DP, French RJ, (2011). Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA. Mol Pharmacol 80: 573-584.
    • (2011) Mol Pharmacol , vol.80 , pp. 573-584
    • McArthur, J.R.1    Singh, G.2    McMaster, D.3    Winkfein, R.4    Tieleman, D.P.5    French, R.J.6
  • 33
    • 77954331629 scopus 로고    scopus 로고
    • Guidelines for reporting experiments involving animals: The ARRIVE guidelines
    • McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
    • (2010) Br J Pharmacol , vol.160 , pp. 1573-1576
    • McGrath, J.1    Drummond, G.2    McLachlan, E.3    Kilkenny, C.4    Wainwright, C.5
  • 34
    • 55249124953 scopus 로고    scopus 로고
    • Sensory neuron voltage-gated sodium channels as analgesic drug targets
    • Momin A, Wood JN, (2008). Sensory neuron voltage-gated sodium channels as analgesic drug targets. Curr Opin Neurobiol 18: 383-388.
    • (2008) Curr Opin Neurobiol , vol.18 , pp. 383-388
    • Momin, A.1    Wood, J.N.2
  • 35
    • 0026527916 scopus 로고
    • Ontogenic development of the TTX-sensitive and TTX-insensitive Na+ channels in neurons of the rat dorsal root ganglia
    • Ogata N, Tatebayashi H, (1992). Ontogenic development of the TTX-sensitive and TTX-insensitive Na+ channels in neurons of the rat dorsal root ganglia. Brain Res Dev Brain Res 65: 93-100.
    • (1992) Brain Res Dev Brain Res , vol.65 , pp. 93-100
    • Ogata, N.1    Tatebayashi, H.2
  • 36
    • 78649469347 scopus 로고    scopus 로고
    • Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
    • Persson A-K, Black JA, Gasser A, Cheng X, Fischer TZ, Waxman SG, (2010). Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals. Mol Pain 6: 84.
    • (2010) Mol Pain , vol.6 , pp. 84
    • Persson, A.-K.1    Black, J.A.2    Gasser, A.3    Cheng, X.4    Fischer, T.Z.5    Waxman, S.G.6
  • 37
    • 0026772987 scopus 로고
    • Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons
    • Roy ML, Narahashi T, (1992). Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons. J Neurosci 12: 2104-2111.
    • (1992) J Neurosci , vol.12 , pp. 2104-2111
    • Roy, M.L.1    Narahashi, T.2
  • 39
    • 33846974357 scopus 로고    scopus 로고
    • Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
    • Rush AM, Cummins TR, Waxman SG, (2007). Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons. J Physiol 579 (Pt 1): 1-14.
    • (2007) J Physiol , vol.579 , Issue.PART 1 , pp. 1-14
    • Rush, A.M.1    Cummins, T.R.2    Waxman, S.G.3
  • 40
    • 0032526716 scopus 로고    scopus 로고
    • Mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes
    • Shon KJ, Olivera BM, Watkins M, Jacobsen RB, Gray WR, Floresca CZ, et al. (1998). mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes. J Neurosci 18: 4473-4481.
    • (1998) J Neurosci , vol.18 , pp. 4473-4481
    • Shon, K.J.1    Olivera, B.M.2    Watkins, M.3    Jacobsen, R.B.4    Gray, W.R.5    Floresca, C.Z.6
  • 41
    • 73549113556 scopus 로고    scopus 로고
    • Excitability parameters and sensitivity to anemone toxin ATX-II in rat small diameter primary sensory neurones discriminated by Griffonia simplicifolia isolectin IB4
    • Snape A, Pittaway JF, Baker MD, (2010). Excitability parameters and sensitivity to anemone toxin ATX-II in rat small diameter primary sensory neurones discriminated by Griffonia simplicifolia isolectin IB4. J Physiol 588 (Pt 1): 125-137.
    • (2010) J Physiol , vol.588 , Issue.PART 1 , pp. 125-137
    • Snape, A.1    Pittaway, J.F.2    Baker, M.D.3
  • 42
    • 0033062951 scopus 로고    scopus 로고
    • Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers
    • Strassman AM, Raymond SA, (1999). Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers. J Neurophysiol 81: 413-424.
    • (1999) J Neurophysiol , vol.81 , pp. 413-424
    • Strassman, A.M.1    Raymond, S.A.2
  • 44
    • 0347989461 scopus 로고    scopus 로고
    • Conus venoms: A rich source of novel ion channel-targeted peptides
    • Terlau H, Olivera BM, (2004). Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol Rev 84: 41-68.
    • (2004) Physiol Rev , vol.84 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 45
    • 80052503806 scopus 로고    scopus 로고
    • Importance of position 8 in mu-conotoxin KIIIA for voltage-gated sodium channel selectivity
    • Van Der Haegen A, Peigneur S, Tytgat J, (2011). Importance of position 8 in mu-conotoxin KIIIA for voltage-gated sodium channel selectivity. FEBS J 278: 3408-3418.
    • (2011) FEBS J , vol.278 , pp. 3408-3418
    • Van Der Haegen, A.1    Peigneur, S.2    Tytgat, J.3
  • 46
    • 0029764479 scopus 로고    scopus 로고
    • Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration
    • Villière V, McLachlan EM, (1996). Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration. J Neurophysiol 76: 1924-1941.
    • (1996) J Neurophysiol , vol.76 , pp. 1924-1941
    • Villière, V.1    McLachlan, E.M.2
  • 47
    • 0027933696 scopus 로고
    • Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy
    • Waxman SG, Kocsis JD, Black JA, (1994). Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy. J Neurophysiol 72: 466-470.
    • (1994) J Neurophysiol , vol.72 , pp. 466-470
    • Waxman, S.G.1    Kocsis, J.D.2    Black, J.A.3
  • 48
    • 0037168454 scopus 로고    scopus 로고
    • Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons
    • West PJ, Bulaj G, Garrett JE, Olivera BM, Yoshikami D, (2002). Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons. Biochemistry 41: 15388-15393.
    • (2002) Biochemistry , vol.41 , pp. 15388-15393
    • West, P.J.1    Bulaj, G.2    Garrett, J.E.3    Olivera, B.M.4    Yoshikami, D.5
  • 49
    • 79960025671 scopus 로고    scopus 로고
    • μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve
    • Wilson MJ, Yoshikami D, Azam L, Gajewiak J, Olivera BM, Bulaj G, et al. (2011). μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve. Proc Natl Acad Sci U S A 108: 10302-10307.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10302-10307
    • Wilson, M.J.1    Yoshikami, D.2    Azam, L.3    Gajewiak, J.4    Olivera, B.M.5    Bulaj, G.6
  • 50
    • 33645237703 scopus 로고    scopus 로고
    • Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels
    • Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, et al. (2006). Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels. Biochemistry 45: 3723-3732.
    • (2006) Biochemistry , vol.45 , pp. 3723-3732
    • Zhang, M.M.1    Fiedler, B.2    Green, B.R.3    Catlin, P.4    Watkins, M.5    Garrett, J.E.6
  • 51
    • 35349024767 scopus 로고    scopus 로고
    • Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels
    • Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, et al. (2007). Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. J Biol Chem 282: 30699-30706.
    • (2007) J Biol Chem , vol.282 , pp. 30699-30706
    • Zhang, M.M.1    Green, B.R.2    Catlin, P.3    Fiedler, B.4    Azam, L.5    Chadwick, A.6
  • 52
    • 66149151034 scopus 로고    scopus 로고
    • Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels
    • Zhang MM, McArthur JR, Azam L, Bulaj G, Olivera BM, French RJ, et al. (2009). Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels. Channels (Austin) 3: 32-38.
    • (2009) Channels (Austin) , vol.3 , pp. 32-38
    • Zhang, M.M.1    McArthur, J.R.2    Azam, L.3    Bulaj, G.4    Olivera, B.M.5    French, R.J.6
  • 53
    • 77954430825 scopus 로고    scopus 로고
    • Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin
    • Zhang MM, Gruszczynski P, Walewska A, Bulaj G, Olivera BM, Yoshikami D, (2010). Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin. J Neurophysiol 104: 88-97.
    • (2010) J Neurophysiol , vol.104 , pp. 88-97
    • Zhang, M.M.1    Gruszczynski, P.2    Walewska, A.3    Bulaj, G.4    Olivera, B.M.5    Yoshikami, D.6


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