메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

AMP Activated Protein Kinase Is Indispensable for Myocardial Adaptation to Caloric Restriction in Mice

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMP ACTIVATED PROTEIN KINASE ALPHA2; HEART ENZYME; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

EID: 84875110092     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059682     Document Type: Article
Times cited : (35)

References (82)
  • 1
    • 0001047561 scopus 로고
    • The Effect of Retardation of Growth Upon the Breeding Period and Duration of Life of Rats
    • Osborne TB, Mendel LB, Ferry EL, (1917) The Effect of Retardation of Growth Upon the Breeding Period and Duration of Life of Rats. Science 45: 294-295.
    • (1917) Science , vol.45 , pp. 294-295
    • Osborne, T.B.1    Mendel, L.B.2    Ferry, E.L.3
  • 3
    • 69949097432 scopus 로고    scopus 로고
    • Caloric restriction-induced life extension of rats and mice: A critique of proposed mechanisms
    • Masoro EJ (2009) Caloric restriction-induced life extension of rats and mice: A critique of proposed mechanisms. Biochim Biophys Acta.
    • (2009) Biochim Biophys Acta
    • Masoro, E.J.1
  • 4
    • 0030466371 scopus 로고    scopus 로고
    • The retardation of aging by caloric restriction: studies in rodents and primates
    • Weindruch R, (1996) The retardation of aging by caloric restriction: studies in rodents and primates. Toxicol Pathol 24: 742-745.
    • (1996) Toxicol Pathol , vol.24 , pp. 742-745
    • Weindruch, R.1
  • 5
  • 6
    • 84866163081 scopus 로고    scopus 로고
    • Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
    • Mattison JA, Roth GS, Beasley TM, Tilmont EM, Handy AM, et al. (2012) Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 489: 318-321.
    • (2012) Nature , vol.489 , pp. 318-321
    • Mattison, J.A.1    Roth, G.S.2    Beasley, T.M.3    Tilmont, E.M.4    Handy, A.M.5
  • 7
    • 77952553450 scopus 로고    scopus 로고
    • Caloric restriction: from soup to nuts
    • Spindler SR, (2010) Caloric restriction: from soup to nuts. Ageing Res Rev 9: 324-353.
    • (2010) Ageing Res Rev , vol.9 , pp. 324-353
    • Spindler, S.R.1
  • 8
    • 14644390872 scopus 로고    scopus 로고
    • Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems
    • Mattson MP, Wan R, (2005) Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems. J Nutr Biochem 16: 129-137.
    • (2005) J Nutr Biochem , vol.16 , pp. 129-137
    • Mattson, M.P.1    Wan, R.2
  • 9
    • 70449864788 scopus 로고    scopus 로고
    • Effects of caloric restriction on cardiovascular aging in non-human primates and humans
    • Cruzen C, Colman RJ (2009) Effects of caloric restriction on cardiovascular aging in non-human primates and humans. Clin Geriatr Med 25: 733-743, ix-x.
    • (2009) Clin Geriatr Med , vol.25
    • Cruzen, C.1    Colman, R.J.2
  • 10
    • 2342647592 scopus 로고    scopus 로고
    • Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
    • Fontana L, Meyer TE, Klein S, Holloszy JO, (2004) Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A 101: 6659-6663.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6659-6663
    • Fontana, L.1    Meyer, T.E.2    Klein, S.3    Holloszy, J.O.4
  • 11
    • 0035140435 scopus 로고    scopus 로고
    • Comparison of the effect of dietary fat restriction with that of energy restriction on human lipid metabolism
    • Raeini-Sarjaz M, Vanstone CA, Papamandjaris AA, Wykes LJ, Jones PJ, (2001) Comparison of the effect of dietary fat restriction with that of energy restriction on human lipid metabolism. Am J Clin Nutr 73: 262-267.
    • (2001) Am J Clin Nutr , vol.73 , pp. 262-267
    • Raeini-Sarjaz, M.1    Vanstone, C.A.2    Papamandjaris, A.A.3    Wykes, L.J.4    Jones, P.J.5
  • 12
    • 0037286229 scopus 로고    scopus 로고
    • Food restriction and fish oil suppress atherogenic risk factors in lupus-prone (NZB x NZW) F1 mice
    • Muthukumar A, Zaman K, Lawrence R, Barnes JL, Fernandes G, (2003) Food restriction and fish oil suppress atherogenic risk factors in lupus-prone (NZB x NZW) F1 mice. J Clin Immunol 23: 23-33.
    • (2003) J Clin Immunol , vol.23 , pp. 23-33
    • Muthukumar, A.1    Zaman, K.2    Lawrence, R.3    Barnes, J.L.4    Fernandes, G.5
  • 13
    • 67649395608 scopus 로고    scopus 로고
    • Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults
    • Viljanen AP, Karmi A, Borra R, Parkka JP, Lepomaki V, et al. (2009) Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults. Am J Cardiol 103: 1721-1726.
    • (2009) Am J Cardiol , vol.103 , pp. 1721-1726
    • Viljanen, A.P.1    Karmi, A.2    Borra, R.3    Parkka, J.P.4    Lepomaki, V.5
  • 14
    • 30344435943 scopus 로고    scopus 로고
    • Long-term caloric restriction ameliorates the decline in diastolic function in humans
    • Meyer TE, Kovacs SJ, Ehsani AA, Klein S, Holloszy JO, et al. (2006) Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol 47: 398-402.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 398-402
    • Meyer, T.E.1    Kovacs, S.J.2    Ehsani, A.A.3    Klein, S.4    Holloszy, J.O.5
  • 15
    • 41549093598 scopus 로고    scopus 로고
    • The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function
    • Riordan MM, Weiss EP, Meyer TE, Ehsani AA, Racette SB, et al. (2008) The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function. Am J Physiol Heart Circ Physiol 294: H1174-1182.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Riordan, M.M.1    Weiss, E.P.2    Meyer, T.E.3    Ehsani, A.A.4    Racette, S.B.5
  • 16
    • 0036756755 scopus 로고    scopus 로고
    • Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls
    • Pamplona R, Portero-Otin M, Requena J, Gredilla R, Barja G, (2002) Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls. Mech Ageing Dev 123: 1437-1446.
    • (2002) Mech Ageing Dev , vol.123 , pp. 1437-1446
    • Pamplona, R.1    Portero-Otin, M.2    Requena, J.3    Gredilla, R.4    Barja, G.5
  • 18
    • 33645987888 scopus 로고    scopus 로고
    • Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction
    • Dhahbi JM, Tsuchiya T, Kim HJ, Mote PL, Spindler SR, (2006) Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction. J Gerontol A Biol Sci Med Sci 61: 218-231.
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , pp. 218-231
    • Dhahbi, J.M.1    Tsuchiya, T.2    Kim, H.J.3    Mote, P.L.4    Spindler, S.R.5
  • 19
    • 77955961614 scopus 로고    scopus 로고
    • Calorie restriction prevents hypertension and cardiac hypertrophy in the spontaneously hypertensive rat
    • Dolinsky VW, Morton JS, Oka T, Robillard-Frayne I, Bagdan M, et al. (2010) Calorie restriction prevents hypertension and cardiac hypertrophy in the spontaneously hypertensive rat. Hypertension 56: 412-421.
    • (2010) Hypertension , vol.56 , pp. 412-421
    • Dolinsky, V.W.1    Morton, J.S.2    Oka, T.3    Robillard-Frayne, I.4    Bagdan, M.5
  • 20
    • 57349200508 scopus 로고    scopus 로고
    • Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1
    • Shinmura K, Tamaki K, Bolli R, (2008) Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1. Am J Physiol Heart Circ Physiol 295: H2348-2355.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Shinmura, K.1    Tamaki, K.2    Bolli, R.3
  • 21
    • 37349051709 scopus 로고    scopus 로고
    • Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase
    • Shinmura K, Tamaki K, Saito K, Nakano Y, Tobe T, et al. (2007) Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase. Circulation 116: 2809-2817.
    • (2007) Circulation , vol.116 , pp. 2809-2817
    • Shinmura, K.1    Tamaki, K.2    Saito, K.3    Nakano, Y.4    Tobe, T.5
  • 22
    • 77951498326 scopus 로고    scopus 로고
    • Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats
    • Wan R, Ahmet I, Brown M, Cheng A, Kamimura N, et al. (2009) Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats. J Nutr Biochem.
    • (2009) J Nutr Biochem
    • Wan, R.1    Ahmet, I.2    Brown, M.3    Cheng, A.4    Kamimura, N.5
  • 23
    • 59149107047 scopus 로고    scopus 로고
    • Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway
    • Katare RG, Kakinuma Y, Arikawa M, Yamasaki F, Sato T, (2009) Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway. J Mol Cell Cardiol 46: 405-412.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 405-412
    • Katare, R.G.1    Kakinuma, Y.2    Arikawa, M.3    Yamasaki, F.4    Sato, T.5
  • 24
    • 33646948539 scopus 로고    scopus 로고
    • Calorie restriction mimetics: an emerging research field
    • Ingram DK, Zhu M, Mamczarz J, Zou S, Lane MA, et al. (2006) Calorie restriction mimetics: an emerging research field. Aging Cell 5: 97-108.
    • (2006) Aging Cell , vol.5 , pp. 97-108
    • Ingram, D.K.1    Zhu, M.2    Mamczarz, J.3    Zou, S.4    Lane, M.A.5
  • 25
    • 34548714671 scopus 로고    scopus 로고
    • Caloric restriction mimetics: a novel approach for biogerontology
    • Lane MA, Roth GS, Ingram DK, (2007) Caloric restriction mimetics: a novel approach for biogerontology. Methods Mol Biol 371: 143-149.
    • (2007) Methods Mol Biol , vol.371 , pp. 143-149
    • Lane, M.A.1    Roth, G.S.2    Ingram, D.K.3
  • 26
    • 1842525838 scopus 로고    scopus 로고
    • Aging, anti-aging, and hormesis
    • Rattan SI, (2004) Aging, anti-aging, and hormesis. Mech Ageing Dev 125: 285-289.
    • (2004) Mech Ageing Dev , vol.125 , pp. 285-289
    • Rattan, S.I.1
  • 27
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R, (1996) Oxidative stress, caloric restriction, and aging. Science 273: 59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 28
    • 0035040549 scopus 로고    scopus 로고
    • The inflammation hypothesis of aging: molecular modulation by calorie restriction
    • Chung HY, Kim HJ, Kim JW, Yu BP, (2001) The inflammation hypothesis of aging: molecular modulation by calorie restriction. Ann N Y Acad Sci 928: 327-335.
    • (2001) Ann N Y Acad Sci , vol.928 , pp. 327-335
    • Chung, H.Y.1    Kim, H.J.2    Kim, J.W.3    Yu, B.P.4
  • 29
    • 3142740860 scopus 로고    scopus 로고
    • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
    • Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, et al. (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305: 390-392.
    • (2004) Science , vol.305 , pp. 390-392
    • Cohen, H.Y.1    Miller, C.2    Bitterman, K.J.3    Wall, N.R.4    Hekking, B.5
  • 30
    • 84868347989 scopus 로고    scopus 로고
    • Caloric restriction: From soup to nuts
    • Spindler SR (2009) Caloric restriction: From soup to nuts. Ageing Res Rev.
    • (2009) Ageing Res Rev
    • Spindler, S.R.1
  • 33
    • 3242777031 scopus 로고    scopus 로고
    • Chronic activation of AMP-activated kinase as a strategy for slowing aging
    • McCarty MF, (2004) Chronic activation of AMP-activated kinase as a strategy for slowing aging. Med Hypotheses 63: 334-339.
    • (2004) Med Hypotheses , vol.63 , pp. 334-339
    • McCarty, M.F.1
  • 34
    • 68649105257 scopus 로고    scopus 로고
    • AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity
    • Greer EL, Banko MR, Brunet A, (2009) AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity. Ann N Y Acad Sci 1170: 688-692.
    • (2009) Ann N Y Acad Sci , vol.1170 , pp. 688-692
    • Greer, E.L.1    Banko, M.R.2    Brunet, A.3
  • 35
    • 58149339613 scopus 로고    scopus 로고
    • Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
    • Narbonne P, Roy R, (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457: 210-214.
    • (2009) Nature , vol.457 , pp. 210-214
    • Narbonne, P.1    Roy, R.2
  • 36
    • 80051609656 scopus 로고    scopus 로고
    • Calorie restriction: is AMPK a key sensor and effector?
    • Canto C, Auwerx J, (2011) Calorie restriction: is AMPK a key sensor and effector? Physiology (Bethesda) 26: 214-224.
    • (2011) Physiology (Bethesda) , vol.26 , pp. 214-224
    • Canto, C.1    Auwerx, J.2
  • 37
    • 0037251455 scopus 로고    scopus 로고
    • The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity
    • Viollet B, Andreelli F, Jorgensen SB, Perrin C, Geloen A, et al. (2003) The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity. J Clin Invest 111: 91-98.
    • (2003) J Clin Invest , vol.111 , pp. 91-98
    • Viollet, B.1    Andreelli, F.2    Jorgensen, S.B.3    Perrin, C.4    Geloen, A.5
  • 38
    • 30944459664 scopus 로고    scopus 로고
    • Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction
    • Tang YD, Kuzman JA, Said S, Anderson BE, Wang X, et al. (2005) Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood flow, loss of arterioles, and severe systolic dysfunction. Circulation 112: 3122-3130.
    • (2005) Circulation , vol.112 , pp. 3122-3130
    • Tang, Y.D.1    Kuzman, J.A.2    Said, S.3    Anderson, B.E.4    Wang, X.5
  • 39
    • 79951670918 scopus 로고    scopus 로고
    • Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts
    • Chen J, Shearer GC, Chen Q, Healy CL, Beyer AJ, et al. (2011) Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts. Circulation 123: 584-593.
    • (2011) Circulation , vol.123 , pp. 584-593
    • Chen, J.1    Shearer, G.C.2    Chen, Q.3    Healy, C.L.4    Beyer, A.J.5
  • 40
    • 34547556463 scopus 로고    scopus 로고
    • Diminished GATA4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury
    • Kobayashi S, Mao K, Zheng H, Wang X, Patterson C, et al. (2007) Diminished GATA4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury. J Biol Chem 282: 21945-21952.
    • (2007) J Biol Chem , vol.282 , pp. 21945-21952
    • Kobayashi, S.1    Mao, K.2    Zheng, H.3    Wang, X.4    Patterson, C.5
  • 41
    • 79959371621 scopus 로고    scopus 로고
    • Caloric restriction mimetic 2-deoxyglucose antagonizes doxorubicin-induced cardiomyocyte death by multiple mechanisms
    • Chen K, Xu X, Kobayashi S, Timm D, Jepperson T, et al. (2011) Caloric restriction mimetic 2-deoxyglucose antagonizes doxorubicin-induced cardiomyocyte death by multiple mechanisms. J Biol Chem 286: 21993-22006.
    • (2011) J Biol Chem , vol.286 , pp. 21993-22006
    • Chen, K.1    Xu, X.2    Kobayashi, S.3    Timm, D.4    Jepperson, T.5
  • 42
    • 0037056109 scopus 로고    scopus 로고
    • Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity
    • Shioji K, Kishimoto C, Nakamura H, Masutani H, Yuan Z, et al. (2002) Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation 106: 1403-1409.
    • (2002) Circulation , vol.106 , pp. 1403-1409
    • Shioji, K.1    Kishimoto, C.2    Nakamura, H.3    Masutani, H.4    Yuan, Z.5
  • 43
    • 78649908644 scopus 로고    scopus 로고
    • Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK
    • Edwards AG, Donato AJ, Lesniewski LA, Gioscia RA, Seals DR, et al. (2010) Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK. Mech Ageing Dev 131: 739-742.
    • (2010) Mech Ageing Dev , vol.131 , pp. 739-742
    • Edwards, A.G.1    Donato, A.J.2    Lesniewski, L.A.3    Gioscia, R.A.4    Seals, D.R.5
  • 44
    • 55949114398 scopus 로고    scopus 로고
    • AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice
    • Zhang P, Hu X, Xu X, Fassett J, Zhu G, et al. (2008) AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice. Hypertension 52: 918-924.
    • (2008) Hypertension , vol.52 , pp. 918-924
    • Zhang, P.1    Hu, X.2    Xu, X.3    Fassett, J.4    Zhu, G.5
  • 45
    • 62149112288 scopus 로고    scopus 로고
    • Why eating less keeps mitochondria working in aged skeletal muscle
    • Hepple RT, (2009) Why eating less keeps mitochondria working in aged skeletal muscle. Exerc Sport Sci Rev 37: 23-28.
    • (2009) Exerc Sport Sci Rev , vol.37 , pp. 23-28
    • Hepple, R.T.1
  • 46
    • 84860468095 scopus 로고    scopus 로고
    • Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
    • Appenzeller-Herzog C, Hall MN, (2012) Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends Cell Biol 22: 274-282.
    • (2012) Trends Cell Biol , vol.22 , pp. 274-282
    • Appenzeller-Herzog, C.1    Hall, M.N.2
  • 47
    • 34548512483 scopus 로고    scopus 로고
    • Autophagy in the heart and liver during normal aging and calorie restriction
    • Wohlgemuth SE, Julian D, Akin DE, Fried J, Toscano K, et al. (2007) Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res 10: 281-292.
    • (2007) Rejuvenation Res , vol.10 , pp. 281-292
    • Wohlgemuth, S.E.1    Julian, D.2    Akin, D.E.3    Fried, J.4    Toscano, K.5
  • 48
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, et al. (2004) The role of autophagy during the early neonatal starvation period. Nature 432: 1032-1036.
    • (2004) Nature , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3    Yamamoto, A.4    Nakaya, H.5
  • 49
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, et al. (2007) Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 100: 914-922.
    • (2007) Circ Res , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3    Abdellatif, M.4    Sakoda, H.5
  • 50
    • 74349090643 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the cardiovascular system
    • Nagata D, Hirata Y, (2009) The role of AMP-activated protein kinase in the cardiovascular system. Hypertens Res 33: 22-28.
    • (2009) Hypertens Res , vol.33 , pp. 22-28
    • Nagata, D.1    Hirata, Y.2
  • 51
    • 34250891313 scopus 로고    scopus 로고
    • AMP-activated protein kinase: a universal regulator of autophagy?
    • Hoyer-Hansen M, Jaattela M, (2007) AMP-activated protein kinase: a universal regulator of autophagy? Autophagy 3: 381-383.
    • (2007) Autophagy , vol.3 , pp. 381-383
    • Hoyer-Hansen, M.1    Jaattela, M.2
  • 52
    • 34249714158 scopus 로고    scopus 로고
    • The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
    • Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, et al. (2007) The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 13: 619-624.
    • (2007) Nat Med , vol.13 , pp. 619-624
    • Nakai, A.1    Yamaguchi, O.2    Takeda, T.3    Higuchi, Y.4    Hikoso, S.5
  • 53
    • 35848967804 scopus 로고    scopus 로고
    • How to Interpret LC3 Immunoblotting
    • Mizushima N, Yoshimori T (2007) How to Interpret LC3 Immunoblotting. Autophagy 3.
    • (2007) Autophagy , vol.3
    • Mizushima, N.1    Yoshimori, T.2
  • 54
    • 34548259958 scopus 로고    scopus 로고
    • p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, et al. (2007) p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 282: 24131-24145.
    • (2007) J Biol Chem , vol.282 , pp. 24131-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5
  • 55
    • 36849089101 scopus 로고    scopus 로고
    • Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice
    • Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, et al. (2007) Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice. Cell 131: 1149-1163.
    • (2007) Cell , vol.131 , pp. 1149-1163
    • Komatsu, M.1    Waguri, S.2    Koike, M.3    Sou, Y.S.4    Ueno, T.5
  • 56
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T, (2007) How to interpret LC3 immunoblotting. Autophagy 3: 542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 57
    • 65249176304 scopus 로고    scopus 로고
    • ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
    • Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, et al. (2009) ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 20: 1992-2003.
    • (2009) Mol Biol Cell , vol.20 , pp. 1992-2003
    • Jung, C.H.1    Jun, C.B.2    Ro, S.H.3    Kim, Y.M.4    Otto, N.M.5
  • 58
    • 77951221542 scopus 로고    scopus 로고
    • The role of the Atg1/ULK1 complex in autophagy regulation
    • Mizushima N, (2010) The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol 22: 132-139.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 132-139
    • Mizushima, N.1
  • 59
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim J, Kundu M, Viollet B, Guan KL, (2011) AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 13: 132-141.
    • (2011) Nat Cell Biol , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 60
    • 81155123729 scopus 로고    scopus 로고
    • The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
    • Bach M, Larance M, James DE, Ramm G, (2011) The serine/threonine kinase ULK1 is a target of multiple phosphorylation events. Biochem J 440: 283-291.
    • (2011) Biochem J , vol.440 , pp. 283-291
    • Bach, M.1    Larance, M.2    James, D.E.3    Ramm, G.4
  • 61
    • 79251587803 scopus 로고    scopus 로고
    • Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
    • Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, et al. (2011) Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 331: 456-461.
    • (2011) Science , vol.331 , pp. 456-461
    • Egan, D.F.1    Shackelford, D.B.2    Mihaylova, M.M.3    Gelino, S.4    Kohnz, R.A.5
  • 62
    • 79955442316 scopus 로고    scopus 로고
    • AMPK, a potential therapeutic target against the transition from cardiac injury to heart failure
    • Beauloye C, Bertrand L, Horman S, Hue L (2011) AMPK, a potential therapeutic target against the transition from cardiac injury to heart failure. Cardiovasc Res.
    • (2011) Cardiovasc Res
    • Beauloye, C.1    Bertrand, L.2    Horman, S.3    Hue, L.4
  • 63
    • 79961039309 scopus 로고    scopus 로고
    • Targeting AMPK for cardiac protection: Opportunities and challenges
    • Kim M, Tian R (2011) Targeting AMPK for cardiac protection: Opportunities and challenges. J Mol Cell Cardiol.
    • (2011) J Mol Cell Cardiol
    • Kim, M.1    Tian, R.2
  • 64
    • 33846250035 scopus 로고    scopus 로고
    • Altered high-energy phosphate metabolism predicts contractile dysfunction and subsequent ventricular remodeling in pressure-overload hypertrophy mice
    • Maslov MY, Chacko VP, Stuber M, Moens AL, Kass DA, et al. (2007) Altered high-energy phosphate metabolism predicts contractile dysfunction and subsequent ventricular remodeling in pressure-overload hypertrophy mice. Am J Physiol Heart Circ Physiol 292: H387-391.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Maslov, M.Y.1    Chacko, V.P.2    Stuber, M.3    Moens, A.L.4    Kass, D.A.5
  • 65
    • 84855182851 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
    • Salminen A, Kaarniranta K, (2012) AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev 11: 230-241.
    • (2012) Ageing Res Rev , vol.11 , pp. 230-241
    • Salminen, A.1    Kaarniranta, K.2
  • 66
    • 8844235617 scopus 로고    scopus 로고
    • The mitochondrial death pathway and cardiac myocyte apoptosis
    • Crow MT, Mani K, Nam YJ, Kitsis RN, (2004) The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 95: 957-970.
    • (2004) Circ Res , vol.95 , pp. 957-970
    • Crow, M.T.1    Mani, K.2    Nam, Y.J.3    Kitsis, R.N.4
  • 67
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri KF, Kroemer G, (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-263.
    • (2001) Nat Cell Biol , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 68
    • 27144489669 scopus 로고    scopus 로고
    • AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
    • Terai K, Hiramoto Y, Masaki M, Sugiyama S, Kuroda T, et al. (2005) AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 25: 9554-9575.
    • (2005) Mol Cell Biol , vol.25 , pp. 9554-9575
    • Terai, K.1    Hiramoto, Y.2    Masaki, M.3    Sugiyama, S.4    Kuroda, T.5
  • 69
    • 27144457438 scopus 로고    scopus 로고
    • Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms
    • Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, et al. (2005) Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat Med 11: 1096-1103.
    • (2005) Nat Med , vol.11 , pp. 1096-1103
    • Shibata, R.1    Sato, K.2    Pimentel, D.R.3    Takemura, Y.4    Kihara, S.5
  • 70
    • 78149279712 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
    • Russell RR III, Li J, Coven DL, Pypaert M, Zechner C, et al. (2004) AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest 114: 495-503.
    • (2004) J Clin Invest , vol.114 , pp. 495-503
    • Russell III, R.R.1    Li, J.2    Coven, D.L.3    Pypaert, M.4    Zechner, C.5
  • 71
    • 77955861146 scopus 로고    scopus 로고
    • Autophagy in health and disease. 5. Mitophagy as a way of life
    • Gottlieb RA, Carreira RS, (2010) Autophagy in health and disease. 5. Mitophagy as a way of life. Am J Physiol Cell Physiol 299: C203-210.
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Gottlieb, R.A.1    Carreira, R.S.2
  • 73
    • 35948982621 scopus 로고    scopus 로고
    • The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction
    • Bergamini E, Cavallini G, Donati A, Gori Z, (2007) The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction. Ann N Y Acad Sci 1114: 69-78.
    • (2007) Ann N Y Acad Sci , vol.1114 , pp. 69-78
    • Bergamini, E.1    Cavallini, G.2    Donati, A.3    Gori, Z.4
  • 75
    • 35848937781 scopus 로고    scopus 로고
    • Autophagy is required for dietary restriction-mediated life span extension in C. elegans
    • Jia K, Levine B, (2007) Autophagy is required for dietary restriction-mediated life span extension in C. elegans. Autophagy 3: 597-599.
    • (2007) Autophagy , vol.3 , pp. 597-599
    • Jia, K.1    Levine, B.2
  • 76
    • 80052511813 scopus 로고    scopus 로고
    • The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
    • Mihaylova MM, Shaw RJ, (2011) The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol 13: 1016-1023.
    • (2011) Nat Cell Biol , vol.13 , pp. 1016-1023
    • Mihaylova, M.M.1    Shaw, R.J.2
  • 77
    • 79951977334 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis
    • Jornayvaz FR, Shulman GI, (2010) Regulation of mitochondrial biogenesis. Essays Biochem 47: 69-84.
    • (2010) Essays Biochem , vol.47 , pp. 69-84
    • Jornayvaz, F.R.1    Shulman, G.I.2
  • 78
    • 3242753501 scopus 로고    scopus 로고
    • Negative regulators of cardiac hypertrophy
    • Hardt SE, Sadoshima J, (2004) Negative regulators of cardiac hypertrophy. Cardiovasc Res 63: 500-509.
    • (2004) Cardiovasc Res , vol.63 , pp. 500-509
    • Hardt, S.E.1    Sadoshima, J.2
  • 79
    • 80052816865 scopus 로고    scopus 로고
    • Targeting GSK-3 family members in the heart: a very sharp double-edged sword
    • Cheng H, Woodgett J, Maamari M, Force T, (2011) Targeting GSK-3 family members in the heart: a very sharp double-edged sword. J Mol Cell Cardiol 51: 607-613.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 607-613
    • Cheng, H.1    Woodgett, J.2    Maamari, M.3    Force, T.4
  • 80
    • 70449706059 scopus 로고    scopus 로고
    • Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling
    • Wu S, Yin R, Ernest R, Li Y, Zhelyabovska O, et al. (2009) Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling. Cardiovasc Res 84: 119-126.
    • (2009) Cardiovasc Res , vol.84 , pp. 119-126
    • Wu, S.1    Yin, R.2    Ernest, R.3    Li, Y.4    Zhelyabovska, O.5
  • 81
    • 79751513700 scopus 로고    scopus 로고
    • Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7
    • Yang Y, Ago T, Zhai P, Abdellatif M, Sadoshima J, (2011) Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7. Circ Res 108: 305-313.
    • (2011) Circ Res , vol.108 , pp. 305-313
    • Yang, Y.1    Ago, T.2    Zhai, P.3    Abdellatif, M.4    Sadoshima, J.5
  • 82
    • 84872013157 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy
    • Lu J, Bian ZY, Zhang R, Zhang Y, Liu C, et al. (2013) Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy. Basic Res Cardiol 108: 326.
    • (2013) Basic Res Cardiol , vol.108 , pp. 326
    • Lu, J.1    Bian, Z.Y.2    Zhang, R.3    Zhang, Y.4    Liu, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.