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Volumn 84, Issue 1, 2009, Pages 119-126

Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-κB signalling

Author keywords

Angiotensin II; Cardiac hypertrophy; Cardiomyocytes; Inflammation; LPS; LXR ; LXR ; NF B

Indexed keywords

ANGIOTENSIN II; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; CELL RECEPTOR; DNA BINDING PROTEIN; FLUORINATED HYDROCARBON; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; SULFONAMIDE; TLR4 PROTEIN, MOUSE; TO-901317; TOLL LIKE RECEPTOR 4;

EID: 70449706059     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp180     Document Type: Article
Times cited : (63)

References (29)
  • 1
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study. N Engl J Med 1990;322:1561-1566.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 2
    • 0034713820 scopus 로고    scopus 로고
    • Left ventricular hypertrophy: Pathogenesis, detection, and prognosis
    • Lorell BH, Carabello BA. Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 2000;102:470-479.
    • (2000) Circulation , vol.102 , pp. 470-479
    • Lorell, B.H.1    Carabello, B.A.2
  • 4
    • 33644859066 scopus 로고    scopus 로고
    • Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha
    • Higuchi Y, Chan TO, Brown MA, Zhang J, DeGeorge BR Jr, Funakoshi H et al. Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha. Am J Physiol Heart Circ Physiol 2006;290:H590-H598.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Higuchi, Y.1    Chan, T.O.2    Brown, M.A.3    Zhang, J.4    Jr D.Br5    Funakoshi, H.6
  • 5
    • 29144512418 scopus 로고    scopus 로고
    • Nifedipine inhibited angio-tensin II-induced monocyte chemoattractant protein 1 expression: Involvement of inhibitor of nuclear factor kappa B kinase and nuclear factor kappa B-inducing kinase
    • Wu L, Iwai M, Li Z, Li JM, Mogi M, Horiuchi M. Nifedipine inhibited angio-tensin II-induced monocyte chemoattractant protein 1 expression: involvement of inhibitor of nuclear factor kappa B kinase and nuclear factor kappa B-inducing kinase. J Hypertens 2006;24:123-130.
    • (2006) J Hypertens , vol.24 , pp. 123-130
    • Wu, L.1    Iwai, M.2    Li, Z.3    Li, J.M.4    Mogi, M.5    Horiuchi, M.6
  • 6
    • 56249140398 scopus 로고    scopus 로고
    • Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
    • Hong C, Tontonoz P. Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr Opin Genet Dev 2008;18:461-467.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 461-467
    • Hong, C.1    Tontonoz, P.2
  • 7
    • 0028117755 scopus 로고
    • Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid hormone receptors
    • Song C, Kokontis JM, Hiipakka RA, Liao S. Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors. Proc Natl Acad Sci USA 1994;91:10809-10813.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10809-10813
    • Song, C.1    Kokontis, J.M.2    Hiipakka, R.A.3    Liao, S.4
  • 10
    • 0033951112 scopus 로고    scopus 로고
    • Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta
    • Alberti S, Steffensen KR, Gustafsson JA. Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta. Gene 2000;243:93-103.
    • (2000) Gene , vol.243 , pp. 93-103
    • Alberti, S.1    Steffensen, K.R.2    Gustafsson, J.A.3
  • 11
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 1996;383:728-731.
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 12
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
    • Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 1998;93:693-704.
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.M.5    Hammer, R.E.6
  • 13
    • 5444235922 scopus 로고    scopus 로고
    • LXR-dependent gene expression is important for macrophage survival and the innate immune response
    • Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L et al. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell 2004;119:299-309.
    • (2004) Cell , vol.119 , pp. 299-309
    • Joseph, S.B.1    Bradley, M.N.2    Castrillo, A.3    Bruhn, K.W.4    Mak, P.A.5    Pei, L.6
  • 15
    • 33646459200 scopus 로고    scopus 로고
    • LXR activation reduces proinflammatory cytokine expression in human CD4-positive lymphocytes
    • Walcher D, Kummel A, Kehrle B, Bach H, Grub M, Durst R et al. LXR activation reduces proinflammatory cytokine expression in human CD4-positive lymphocytes. Arterioscler Thromb Vasc Biol 2006;26: 1022-1028.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1022-1028
    • Walcher, D.1    Kummel, A.2    Kehrle, B.3    Bach, H.4    Grub, M.5    Durst, R.6
  • 16
    • 27744552599 scopus 로고    scopus 로고
    • Suppression of inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 22(R)-hydroxycholesterol requires de novo protein synthesis in activated macrophages
    • Yasuda T, Kanno M, Kawamoto M, Yuge O, Ninomiya Y. Suppression of inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 22(R)-hydroxycholesterol requires de novo protein synthesis in activated macrophages. J Steroid Biochem Mol Biol 2005;97:376-383.
    • (2005) J Steroid Biochem Mol Biol , vol.97 , pp. 376-383
    • Yasuda, T.1    Kanno, M.2    Kawamoto, M.3    Yuge, O.4    Ninomiya, Y.5
  • 17
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 2006;116:607-614.
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 18
    • 0028982834 scopus 로고
    • Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes
    • Thaik CM, Calderone A, Takahashi N, Colucci WS. Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest 1995;96:1093-1099.
    • (1995) J Clin Invest , vol.96 , pp. 1093-1099
    • Thaik, C.M.1    Calderone, A.2    Takahashi, N.3    Colucci, W.S.4
  • 19
    • 0037372065 scopus 로고    scopus 로고
    • The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
    • Laffitte BA, Joseph SB, Chen M, Castrillo A, Repa J, Wilpitz D et al. The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions. Mol Cell Biol 2003;23: 2182-2191.
    • (2003) Mol Cell Biol , vol.23 , pp. 2182-2191
    • Laffitte, B.A.1    Joseph, S.B.2    Chen, M.3    Castrillo, A.4    Repa, J.5    Wilpitz, D.6
  • 21
    • 0026709274 scopus 로고
    • Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy
    • Sadoshima J, Jahn L, Takahashi T, Kulik TJ, Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy. J Biol Chem 1992;267: 10551-10560.
    • (1992) J Biol Chem , vol.267 , pp. 10551-10560
    • Sadoshima, J.1    Jahn, L.2    Takahashi, T.3    Kulik, T.J.4    Izumo, S.5
  • 22
    • 44449120184 scopus 로고    scopus 로고
    • Lipopolysacchar-ide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells
    • Liu CJ, Cheng YC, Lee KW, Hsu HH, Chu CH, Tsai FJ et al. Lipopolysacchar-ide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells. Mol Cell Biochem 2008;313:167-178.
    • (2008) Mol Cell Biochem , vol.313 , pp. 167-178
    • Liu, C.J.1    Cheng, Y.C.2    Lee, K.W.3    Hsu, H.H.4    Chu, C.H.5    Tsai, F.J.6
  • 23
    • 33646785780 scopus 로고    scopus 로고
    • Activation of the liver X receptor protects against hepatic injury in endotox-emia by suppressing Kupffer cell activation
    • Wang YY, Dahle MK, Agren J, Myhre AE, Reinholt FP, Foster SJ et al. Activation of the liver X receptor protects against hepatic injury in endotox-emia by suppressing Kupffer cell activation. Shock 2006;25:141-146.
    • (2006) Shock , vol.25 , pp. 141-146
    • Wang, Y.Y.1    Dahle, M.K.2    Agren, J.3    Myhre, A.E.4    Reinholt, F.P.5    Foster, S.J.6
  • 24
    • 0042519617 scopus 로고    scopus 로고
    • A20 is dynamically regulated in the heart and inhibits the hypertrophic response
    • Cook SA, Novikov MS, Ahn Y, Matsui T, Rosenzweig A. A20 is dynamically regulated in the heart and inhibits the hypertrophic response. Circulation 2003;108:664-667.
    • (2003) Circulation , vol.108 , pp. 664-667
    • Cook, S.A.1    Novikov, M.S.2    Ahn, Y.3    Matsui, T.4    Rosenzweig, A.5
  • 25
    • 0031918203 scopus 로고    scopus 로고
    • Tumor necrosis factor in the heart
    • Meldrum DR. Tumor necrosis factor in the heart. Am J Physiol 1998;274: R577-R595.
    • (1998) Am J Physiol , vol.274
    • Meldrum, D.R.1
  • 26
    • 0030689717 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion
    • Gurevitch J, Frolkis I, Yuhas Y, Lifschitz-Mercer B, Berger E, Paz Y et al. Anti-tumor necrosis factor-alpha improves myocardial recovery after ischemia and reperfusion. J Am Coll Cardiol 1997;30:1554-1561.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1554-1561
    • Gurevitch, J.1    Frolkis, I.2    Yuhas, Y.3    Lifschitz-Mercer, B.4    Berger, E.5    Paz, Y.6
  • 27
    • 0035089375 scopus 로고    scopus 로고
    • Elevated interleukin-6 levels in patients with asymptomatic left ventricular systolic dysfunction
    • Raymond RJ, Dehmer GJ, Theoharides TC, Deliargyris EN. Elevated interleukin-6 levels in patients with asymptomatic left ventricular systolic dysfunction. Am Heart J 2001;141:435-438.
    • (2001) Am Heart J , vol.141 , pp. 435-438
    • Raymond, R.J.1    Dehmer, G.J.2    Theoharides, T.C.3    Deliargyris, E.N.4
  • 28
    • 34447622686 scopus 로고    scopus 로고
    • Liver X receptor activation potentiates the lipopolysaccharide response in human macrophages
    • Fontaine C, Rigamonti E, Nohara A, Gervois P, Teissier E, Fruchart JC et al. Liver X receptor activation potentiates the lipopolysaccharide response in human macrophages. Circ Res 2007;101:40-49.
    • (2007) Circ Res , vol.101 , pp. 40-49
    • Fontaine, C.1    Rigamonti, E.2    Nohara, A.3    Gervois, P.4    Teissier, E.5    Fruchart, J.C.6
  • 29
    • 45849096800 scopus 로고    scopus 로고
    • Liver X receptor activator downregulates angiotensin II type 1 receptor expression through dephosphorylation of Sp1
    • Imayama I, Ichiki T, Patton D, Inanaga K, Miyazaki R, Ohtsubo H et al. Liver X receptor activator downregulates angiotensin II type 1 receptor expression through dephosphorylation of Sp1. Hypertension 2008;51: 1631-1636.
    • (2008) Hypertension , vol.51 , pp. 1631-1636
    • Imayama, I.1    Ichiki, T.2    Patton, D.3    Inanaga, K.4    Miyazaki, R.5    Ohtsubo, H.6


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