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Volumn 33, Issue 1, 2010, Pages 22-28

The role of AMP-activated protein kinase in the cardiovascular system

Author keywords

AMPK; Atherosclerosis; Vascular endothelial cell

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE LKB1;

EID: 74349090643     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2009.187     Document Type: Review
Times cited : (66)

References (43)
  • 2
    • 0037059013 scopus 로고    scopus 로고
    • Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
    • Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc C, Itani SI, Lodish HF, Ruderman NB. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002; 99: 16309-16313.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16309-16313
    • Tomas, E.1    Tsao, T.S.2    Saha, A.K.3    Murrey, H.E.4    Zhang Cc, C.5    Itani, S.I.6    Lodish, H.F.7    Ruderman, N.B.8
  • 3
    • 0037067666 scopus 로고    scopus 로고
    • The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
    • Fryer LG, Parbu-Patel A, Carling D. The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem 2002; 277: 25226-25232.
    • (2002) J Biol Chem , vol.277 , pp. 25226-25232
    • Fryer, L.G.1    Parbu-Patel, A.2    Carling, D.3
  • 4
    • 33744976813 scopus 로고    scopus 로고
    • Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Hattori S, Kasai K. Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 2006; 47: 1183-1188.
    • (2006) Hypertension , vol.47 , pp. 1183-1188
    • Hattori, Y.1    Suzuki, K.2    Hattori, S.3    Kasai, K.4
  • 5
    • 20044372016 scopus 로고    scopus 로고
    • Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells
    • Konrad D, Rudich A, Bilan PJ, Patel N, Richardson C, Witters LA, Klip A. Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells. Diabetologia 2005; 48: 954-966.
    • (2005) Diabetologia , vol.48 , pp. 954-966
    • Konrad, D.1    Rudich, A.2    Bilan, P.J.3    Patel, N.4    Richardson, C.5    Witters, L.A.6    Klip, A.7
  • 6
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
    • Hardie DG. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 2003; 144: 5179-5183.
    • (2003) Endocrinology , vol.144 , pp. 5179-5183
    • Hardie, D.G.1
  • 7
    • 15044358594 scopus 로고    scopus 로고
    • New roles for the LKB1-AMPK pathway
    • Hardie DG. New roles for the LKB1-AMPK pathway. Curr Opin Cell Biol 2005; 17: 167-173.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 167-173
    • Hardie, D.G.1
  • 9
    • 33846030181 scopus 로고    scopus 로고
    • A revised model for AMP-activated protein kinase structure: The alpha-subunit binds to both the beta-and gamma-subunits although there is no direct binding between the beta-and gamma-subunits
    • Wong KA, Lodish HF. A revised model for AMP-activated protein kinase structure: the alpha-subunit binds to both the beta-and gamma-subunits although there is no direct binding between the beta-and gamma-subunits. J Biol Chem 2006; 281: 36434-36442.
    • (2006) J Biol Chem , vol.281 , pp. 36434-36442
    • Wong, K.A.1    Lodish, H.F.2
  • 10
    • 0041305909 scopus 로고    scopus 로고
    • Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases
    • Hong SP, Leiper FC, Woods A, Carling D, Carlson M. Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc Natl Acad Sci USA 2003; 100: 8839-8843.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8839-8843
    • Hong, S.P.1    Leiper, F.C.2    Woods, A.3    Carling, D.4    Carlson, M.5
  • 11
    • 0345107247 scopus 로고    scopus 로고
    • Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/ beta are upstream kinases in the AMP-activated protein kinase cascade
    • Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Makela TP, Alessi DR, Hardie DG. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/ beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2003; 2: 28.
    • (2003) J Biol , vol.2 , pp. 28
    • Hawley, S.A.1    Boudeau, J.2    Reid, J.L.3    Mustard, K.J.4    Udd, L.5    Makela, T.P.6    Alessi, D.R.7    Hardie, D.G.8
  • 15
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • Zong H, Ren JM, Young LH, Pypaert M, Mu J, Birnbaum MJ, Shulman GI. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci USA 2002; 99: 15983-15987.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3    Pypaert, M.4    Mu, J.5    Birnbaum, M.J.6    Shulman, G.I.7
  • 16
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell 2003; 115: 577-590.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 17
    • 0034090975 scopus 로고    scopus 로고
    • The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry
    • Watts JL, Morton DG, Bestman J, Kemphues KJ. The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry. Development 2000; 127: 1467-1475.
    • (2000) Development , vol.127 , pp. 1467-1475
    • Watts, J.L.1    Morton, D.G.2    Bestman, J.3    Kemphues, K.J.4
  • 18
    • 0037461735 scopus 로고    scopus 로고
    • A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
    • Martin SG, St Johnston D. A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 2003; 421: 379-384.
    • (2003) Nature , vol.421 , pp. 379-384
    • Martin, S.G.1    St Johnston, D.2
  • 21
    • 33846521353 scopus 로고    scopus 로고
    • Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
    • Zheng B, Cantley LC. Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc Natl Acad Sci USA 2007; 104: 819-822.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 819-822
    • Zheng, B.1    Cantley, L.C.2
  • 22
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463-477.
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 23
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B, Sadoshima J. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007; 100: 914-922.
    • (2007) Circ Res , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3    Abdellatif, M.4    Sakoda, H.5    Asano, T.6    Levine, B.7    Sadoshima, J.8
  • 25
    • 0030938190 scopus 로고    scopus 로고
    • Upregulation of 5¢-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit
    • Makinde AO, Gamble J, Lopaschuk GD. Upregulation of 5¢-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit. Circ Res 1997; 80: 482-489.
    • (1997) Circ Res , vol.80 , pp. 482-489
    • Makinde, A.O.1    Gamble, J.2    Lopaschuk, G.D.3
  • 27
    • 0029093341 scopus 로고
    • High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5¢-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase
    • Kudo N, Barr AJ, Barr RL, Desai S, Lopaschuk GD. High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5¢-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase. J Biol Chem 1995; 270: 17513-17520.
    • (1995) J Biol Chem , vol.270 , pp. 17513-17520
    • Kudo, N.1    Barr, A.J.2    Barr, R.L.3    Desai, S.4    Lopaschuk, G.D.5
  • 28
    • 0032881635 scopus 로고    scopus 로고
    • Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
    • Russell III RR, Bergeron R, Shulman GI, Young LH. Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am J Physiol 1999; 277: H643-H649.
    • (1999) Am J Physiol , vol.277
    • Russell Iii, R.R.1    Bergeron, R.2    Shulman, G.I.3    Young, L.H.4
  • 34
    • 33947526130 scopus 로고    scopus 로고
    • AMP-activated protein kinase in the heart: Role during health and disease
    • Arad M, Seidman CE, Seidman JG. AMP-activated protein kinase in the heart: role during health and disease. Circ Res 2007; 100: 474-488.
    • (2007) Circ Res , vol.100 , pp. 474-488
    • Arad, M.1    Seidman, C.E.2    Seidman, J.G.3
  • 35
    • 0042733154 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress
    • Nagata D, Mogi M, Walsh K. AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress. J Biol Chem 2003; 278: 31000-31006.
    • (2003) J Biol Chem , vol.278 , pp. 31000-31006
    • Nagata, D.1    Mogi, M.2    Walsh, K.3
  • 36
    • 68249152343 scopus 로고    scopus 로고
    • A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell
    • Nagata D, Kiyosue A, Takahashi M, Satonaka H, Tanaka K, Sata M, Nagano T, Nagai R, Hirata Y. A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell. Hypertens Res 2009; 32: 133-139.
    • (2009) Hypertens Res , vol.32 , pp. 133-139
    • Nagata, D.1    Kiyosue, A.2    Takahashi, M.3    Satonaka, H.4    Tanaka, K.5    Sata, M.6    Nagano, T.7    Nagai, R.8    Hirata, Y.9
  • 37
    • 0346463030 scopus 로고    scopus 로고
    • Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and akt signaling in endothelial cells
    • DOI 10.1074/jbc.M310389200
    • Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, Funahashi T, Walsh K. Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells. J Biol Chem 2004; 279: 1304-1309. (Pubitemid 38082655)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.2 , pp. 1304-1309
    • Ouchi, N.1    Kobayashi, H.2    Kihara, S.3    Kumada, M.4    Sato, K.5    Inoue, T.6    Funahashi, T.7    Walsh, K.8
  • 38
    • 2342476366 scopus 로고    scopus 로고
    • High-density lipoprotein and apolipoprotein AI increase endothelial NO synthase activity by protein association and multisite phosphorylation
    • Drew BG, Fidge NH, Gallon-Beaumier G, Kemp BE, Kingwell BA. High-density lipoprotein and apolipoprotein AI increase endothelial NO synthase activity by protein association and multisite phosphorylation. Proc Natl Acad Sci USA 2004; 101: 6999-7004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6999-7004
    • Drew, B.G.1    Fidge, N.H.2    Gallon-Beaumier, G.3    Kemp, B.E.4    Kingwell, B.A.5
  • 39
    • 0036095269 scopus 로고    scopus 로고
    • Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation
    • Ido Y, Carling D, Ruderman N. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation. Diabetes 2002; 51: 159-167.
    • (2002) Diabetes , vol.51 , pp. 159-167
    • Ido, Y.1    Carling, D.2    Ruderman, N.3
  • 42
    • 3342915617 scopus 로고    scopus 로고
    • AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation
    • Nagata D, Takeda R, Sata M, Satonaka H, Suzuki E, Nagano T, Hirata Y. AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation. Circulation 2004; 110: 444-451.
    • (2004) Circulation , vol.110 , pp. 444-451
    • Nagata, D.1    Takeda, R.2    Sata, M.3    Satonaka, H.4    Suzuki, E.5    Nagano, T.6    Hirata, Y.7
  • 43
    • 39449120283 scopus 로고    scopus 로고
    • Thromboxane receptor activates the AMP-activated protein kinase in vascular smooth muscle cells via hydrogen peroxide
    • Zhang M, Dong Y, Xu J, Xie Z, Wu Y, Song P, Guzman M, Wu J, Zou MH. Thromboxane receptor activates the AMP-activated protein kinase in vascular smooth muscle cells via hydrogen peroxide. Circ Res 2008; 102: 328-337.
    • (2008) Circ Res , vol.102 , pp. 328-337
    • Zhang, M.1    Dong, Y.2    Xu, J.3    Xie, Z.4    Wu, Y.5    Song, P.6    Guzman, M.7    Wu, J.8    Zou, M.H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.