Inhibition of phosphodiesterase-5 rescues age-related impairment of synaptic plasticity and memory

Behavioural Brain Research

Volumn 240, Issue , 2013, Pages 11-20

  Palmeri, Agostino ^a   Privitera, Lucia ^a   Giunta, Salvatore ^a   Loreto, Carla ^a   Puzzo, Daniela ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Aging; CREB; Hippocampus; Memory; Sildenafil; Synaptic plasticity

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC GMP; SILDENAFIL;

AGE DISTRIBUTION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN PERFUSION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; ENZYME INHIBITION; FEMALE; HIPPOCAMPUS; MALE; MEMORY DISORDER; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECOGNITION; REFERENCE MEMORY; SPATIAL LEARNING; TREATMENT DURATION; TREATMENT OUTCOME;

AGING; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC GMP; FEMALE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHORYLATION; PIPERAZINES; PURINES; RECOGNITION (PSYCHOLOGY); SULFONES; SYNAPTIC TRANSMISSION;

EID: 84875080648     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.10.060     Document Type: Article

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