Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade

Neuroscience

Volumn 159, Issue 4, 2009, Pages 1208-1215

  Li, Q ^a   Zhao, H F ^a   Zhang, Z F ^a   Liu, Z G ^a   Pei, X R ^a   Wang, J B ^a   Cai, M Y ^b   Li, Y ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

Author keywords

Bcl 2; BDNF; CREB; green tea catechins; learning and memory; Morris water maze

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CATECHIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GREEN TEA EXTRACT; NEUROTROPHIC FACTOR; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN LEVEL; CELL DENSITY; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HIPPOCAMPUS; LEARNING DISORDER; LOCOMOTION; MAZE TEST; MEMORY DISORDER; NERVE CELL PLASTICITY; NISSL STAINING; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

AGING; ANIMALS; ANTIOXIDANTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CATECHIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEARNING; MAZE LEARNING; MEMBRANE PROTEINS; MEMORY; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; SPACE PERCEPTION;

EID: 63349105631     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.02.008     Document Type: Article

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