A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 49, 2009, Pages 20788-20793

  Taimen, Pekka ^a   Pfleghaar, Katrin ^a   Shimi, Takeshi ^a   Möller, Dorothee ^b   Ben Harush, Kfir ^c   Erdos, Michael R ^d   Adam, Stephen A ^a   Herrmann, Harald ^b   Medalia, Ohad ^c   Collins, Francis S ^d   Goldman, Anne E ^a   Goldman, Robert D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

Centromere; Chromatin; Rabl; Senescence; Telomere

Indexed keywords

LAMIN A; LAMIN B;

ARTICLE; CELL NUCLEUS MEMBRANE; CHROMOSOME STRUCTURE; CONTROLLED STUDY; CYTOARCHITECTURE; GENE MUTATION; HETEROCHROMATIN; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS RATE; PRIORITY JOURNAL; PROGERIA; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID SUBSTITUTION; CELL NUCLEUS; CENTROMERE; CHROMOSOME POSITIONING; CHROMOSOMES, HUMAN; CRYSTALLIZATION; DNA REPLICATION; HELA CELLS; HETEROCHROMATIN; HUMANS; LAMIN TYPE A; MALE; MITOSIS; MUTANT PROTEINS; MUTATION; PROGERIA; TELOMERE;

EID: 73949136181     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911895106     Document Type: Article

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