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Volumn 94, Issue 2, 2013, Pages 386-397

Cytomegalovirus-induced salivary gland pathology: AREG, FGF8, TNF-α, and IL-6 signal dysregulation and neoplasia

Author keywords

AREG; CMV induced pathology; Cytomegalovirus; FGF8; IL 6; Salivary gland; TNF

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ACICLOVIR; AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR; GEFITINIB; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RAF PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 84874765888     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2013.01.005     Document Type: Article
Times cited : (8)

References (57)
  • 1
    • 70449520174 scopus 로고    scopus 로고
    • Malignant salivary gland tumors and cyclo-oxygenase-2: a histopathological and immunohistochemical analysis with implications on histogenesis
    • Akrish S., Peled M., Ben-Izhak B., Nagler R.M. Malignant salivary gland tumors and cyclo-oxygenase-2: a histopathological and immunohistochemical analysis with implications on histogenesis. Oral Oncology 2009, 45:1044-1050.
    • (2009) Oral Oncology , vol.45 , pp. 1044-1050
    • Akrish, S.1    Peled, M.2    Ben-Izhak, B.3    Nagler, R.M.4
  • 2
    • 84866949049 scopus 로고    scopus 로고
    • The human cytomegalovirus assembly compartment: a masterpiece of viral manipulation of cellular processes that facilitates assembly and egress
    • Alwine J.C. The human cytomegalovirus assembly compartment: a masterpiece of viral manipulation of cellular processes that facilitates assembly and egress. PLoS Pathogens 2012, 8:e1002878.
    • (2012) PLoS Pathogens , vol.8
    • Alwine, J.C.1
  • 5
    • 84860852345 scopus 로고    scopus 로고
    • Salivary gland cancers: biology and molecular targets for therapy
    • Bell D., Hanna E.Y. Salivary gland cancers: biology and molecular targets for therapy. Current Oncology Reports 2012, 14:166-174.
    • (2012) Current Oncology Reports , vol.14 , pp. 166-174
    • Bell, D.1    Hanna, E.Y.2
  • 6
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick N.A., Neilson E.G., Moses H.L. Stromal fibroblasts in cancer initiation and progression. Nature 2004, 432:332-337.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 8
    • 0019468719 scopus 로고
    • Thymidine kinase not required for antiviral activity of acyclovir against mouse cytomegalovirus
    • Burns W.H., Wingard J.R., Bender W.J., Saral R. Thymidine kinase not required for antiviral activity of acyclovir against mouse cytomegalovirus. Journal of Virology 1981, 39:889-893.
    • (1981) Journal of Virology , vol.39 , pp. 889-893
    • Burns, W.H.1    Wingard, J.R.2    Bender, W.J.3    Saral, R.4
  • 9
    • 84857680685 scopus 로고    scopus 로고
    • Cell biology. Reconfiguring regulation
    • Chalancon G., Kruse K., Babu M.M. Cell biology. Reconfiguring regulation. Science 2012, 335:1050-1051.
    • (2012) Science , vol.335 , pp. 1050-1051
    • Chalancon, G.1    Kruse, K.2    Babu, M.M.3
  • 11
  • 17
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 19
    • 0032754678 scopus 로고    scopus 로고
    • Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations
    • Jaskoll T., Melnick M. Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations. Anatomical Record 1999, 256:252-268.
    • (1999) Anatomical Record , vol.256 , pp. 252-268
    • Jaskoll, T.1    Melnick, M.2
  • 20
    • 0035218444 scopus 로고    scopus 로고
    • Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice
    • Jaskoll T., Zhou Y.M., Chai Y., Makarenkova H.P., Collinson J.M., West J.D., Hajihosseini M.K., Lee J., Melnick M. Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells, Tissues, Organs 2002, 170:83-98.
    • (2002) Cells, Tissues, Organs , vol.170 , pp. 83-98
    • Jaskoll, T.1    Zhou, Y.M.2    Chai, Y.3    Makarenkova, H.P.4    Collinson, J.M.5    West, J.D.6    Hajihosseini, M.K.7    Lee, J.8    Melnick, M.9
  • 22
    • 78751529619 scopus 로고    scopus 로고
    • CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer
    • Jaskoll T., Htet K., Abichaker G., Kaye F.J., Melnick M. CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer. Gene Expression Patterns 2011, 11:57-63.
    • (2011) Gene Expression Patterns , vol.11 , pp. 57-63
    • Jaskoll, T.1    Htet, K.2    Abichaker, G.3    Kaye, F.J.4    Melnick, M.5
  • 23
    • 27744506127 scopus 로고    scopus 로고
    • Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction
    • Jullien J., Gurdon J. Morphogen gradient interpretation by a regulated trafficking step during ligand-receptor transduction. Genes & Development 2005, 19:2682-2694.
    • (2005) Genes & Development , vol.19 , pp. 2682-2694
    • Jullien, J.1    Gurdon, J.2
  • 24
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • Karin M., C.Y., Greten F.R., Li Z.W. NF-kappaB in cancer: from innocent bystander to major culprit. Nature Reviews. Cancer 2002, 2:301-310.
    • (2002) Nature Reviews. Cancer , vol.2 , pp. 301-310
    • Karin, M.C.Y.1    Greten, F.R.2    Li, Z.W.3
  • 25
    • 0034656224 scopus 로고    scopus 로고
    • The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF
    • Kashimata M., Sayeed S., Ka A., Onetti-Muda A., Sakagami H., Faraggiana T., Gresik E.W. The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF. Developmental Biology 2000, 220:183-196.
    • (2000) Developmental Biology , vol.220 , pp. 183-196
    • Kashimata, M.1    Sayeed, S.2    Ka, A.3    Onetti-Muda, A.4    Sakagami, H.5    Faraggiana, T.6    Gresik, E.W.7
  • 26
    • 84864761135 scopus 로고    scopus 로고
    • Systems biology. Modular biological complexity
    • Koch C. Systems biology. Modular biological complexity. Science 2012, 337:531-532.
    • (2012) Science , vol.337 , pp. 531-532
    • Koch, C.1
  • 27
    • 0038282450 scopus 로고    scopus 로고
    • EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland
    • Koyama N., Kashimata M., Sakashita H., Sakagami H., Gresik E.W. EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Developmental Dynamics 2003, 227:216-226.
    • (2003) Developmental Dynamics , vol.227 , pp. 216-226
    • Koyama, N.1    Kashimata, M.2    Sakashita, H.3    Sakagami, H.4    Gresik, E.W.5
  • 31
    • 84857538593 scopus 로고    scopus 로고
    • Disease tolerance as a defense strategy
    • Medzhitov R., Schneider D.S., Soares M.P. Disease tolerance as a defense strategy. Science 2012, 335:936-941.
    • (2012) Science , vol.335 , pp. 936-941
    • Medzhitov, R.1    Schneider, D.S.2    Soares, M.P.3
  • 32
    • 0033940143 scopus 로고    scopus 로고
    • Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing
    • Melnick M., Jaskoll T. Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing. Critical Reviews in Oral Biology and Medicine 2000, 11:199-215.
    • (2000) Critical Reviews in Oral Biology and Medicine , vol.11 , pp. 199-215
    • Melnick, M.1    Jaskoll, T.2
  • 33
    • 0035087790 scopus 로고    scopus 로고
    • Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis
    • Melnick M., Chen H., Zhou Y.M., Jaskoll T. Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis. Cells, Tissues, Organs 2001, 168:233-245.
    • (2001) Cells, Tissues, Organs , vol.168 , pp. 233-245
    • Melnick, M.1    Chen, H.2    Zhou, Y.M.3    Jaskoll, T.4
  • 34
    • 3042724638 scopus 로고    scopus 로고
    • The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition
    • Melnick M., Chen H., Min Zhou Y., Jaskoll T. The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition. BMC Developmental Biology 2001, 1:15.
    • (2001) BMC Developmental Biology , vol.1 , pp. 15
    • Melnick, M.1    Chen, H.2    Min Zhou, Y.3    Jaskoll, T.4
  • 35
    • 0035283040 scopus 로고    scopus 로고
    • Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway
    • Melnick M., Chen H., Zhou Y., Jaskoll T. Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway. Anatomical Record 2001, 262:318-330.
    • (2001) Anatomical Record , vol.262 , pp. 318-330
    • Melnick, M.1    Chen, H.2    Zhou, Y.3    Jaskoll, T.4
  • 36
    • 33750029434 scopus 로고    scopus 로고
    • Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model
    • Melnick M., Mocarski E.S., Abichaker G., Huang J., Jaskoll T. Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model. BMC Developmental Biology 2006, 6:42.
    • (2006) BMC Developmental Biology , vol.6 , pp. 42
    • Melnick, M.1    Mocarski, E.S.2    Abichaker, G.3    Huang, J.4    Jaskoll, T.5
  • 37
    • 67649580786 scopus 로고    scopus 로고
    • Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm
    • Melnick M., Phair R.D., Lapidot S.A., Jaskoll T. Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Developmental Biology 2009, 9:32.
    • (2009) BMC Developmental Biology , vol.9 , pp. 32
    • Melnick, M.1    Phair, R.D.2    Lapidot, S.A.3    Jaskoll, T.4
  • 38
    • 79960426036 scopus 로고    scopus 로고
    • Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis
    • Melnick M., Abichaker G., Htet K., Sedghizadeh P., Jaskoll T. Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis. Experimental and Molecular Pathology 2011, 1:400-410.
    • (2011) Experimental and Molecular Pathology , vol.1 , pp. 400-410
    • Melnick, M.1    Abichaker, G.2    Htet, K.3    Sedghizadeh, P.4    Jaskoll, T.5
  • 39
    • 82255169334 scopus 로고    scopus 로고
    • Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship
    • Melnick M., Sedghizadeh P.P., Allen C.M., Jaskoll T. Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship. Experimental and Molecular Pathology 2012, 92:118-125.
    • (2012) Experimental and Molecular Pathology , vol.92 , pp. 118-125
    • Melnick, M.1    Sedghizadeh, P.P.2    Allen, C.M.3    Jaskoll, T.4
  • 41
    • 0033959463 scopus 로고    scopus 로고
    • Recent advances in the therapy and prevention of CMV infections
    • Nichols W.G., Boeckh M. Recent advances in the therapy and prevention of CMV infections. Journal of Clinical Virology 2000, 16:25-40.
    • (2000) Journal of Clinical Virology , vol.16 , pp. 25-40
    • Nichols, W.G.1    Boeckh, M.2
  • 42
    • 77952568396 scopus 로고    scopus 로고
    • Hallmarks of cancer: interactions with the tumor stroma
    • Pietras K., Ostman A. Hallmarks of cancer: interactions with the tumor stroma. Experimental Cell Research 2010, 316:1324-1331.
    • (2010) Experimental Cell Research , vol.316 , pp. 1324-1331
    • Pietras, K.1    Ostman, A.2
  • 43
    • 79953234255 scopus 로고    scopus 로고
    • Resistance to MEK inhibitors: should we co-target upstream?
    • Poulikakos P.I., Solit D.B. Resistance to MEK inhibitors: should we co-target upstream?. Science Signaling 2011, 4:pe16.
    • (2011) Science Signaling , vol.4
    • Poulikakos, P.I.1    Solit, D.B.2
  • 44
    • 25444468618 scopus 로고    scopus 로고
    • Noise in gene expression: origins, consequences, and control
    • Raser J.M., O'Shea E.K. Noise in gene expression: origins, consequences, and control. Science 2005, 309:2010-2013.
    • (2005) Science , vol.309 , pp. 2010-2013
    • Raser, J.M.1    O'Shea, E.K.2
  • 48
    • 80054100952 scopus 로고    scopus 로고
    • Congenital cytomegalovirus infection: molecular mechanisms mediating viral pathogenesis
    • Schleiss M.R. Congenital cytomegalovirus infection: molecular mechanisms mediating viral pathogenesis. Infectious Disorders Drug Targets 2011, 11:449-465.
    • (2011) Infectious Disorders Drug Targets , vol.11 , pp. 449-465
    • Schleiss, M.R.1
  • 49
    • 79952713252 scopus 로고    scopus 로고
    • Salivary gland mucoepidermoid carcinoma is a clinically, morphologically and genetically heterogeneous entity: a clinicopathological study of 40 cases with emphasis on grading, histological variants and presence of the t(11;19) translocation
    • Schwarz S., Stiegler C., Müller M., Ettl T., Brockhoff G., Zenk J., Agaimy A. Salivary gland mucoepidermoid carcinoma is a clinically, morphologically and genetically heterogeneous entity: a clinicopathological study of 40 cases with emphasis on grading, histological variants and presence of the t(11;19) translocation. Histopathology 2011, 58:557-570.
    • (2011) Histopathology , vol.58 , pp. 557-570
    • Schwarz, S.1    Stiegler, C.2    Müller, M.3    Ettl, T.4    Brockhoff, G.5    Zenk, J.6    Agaimy, A.7
  • 53
    • 34249081691 scopus 로고    scopus 로고
    • CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior
    • Tirado Y., Williams M.D., Hanna E.Y., Kaye F.J., Batsakis J.G., El-Naggar A.K. CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior. Genes, Chromosomes & Cancer 2007, 46:708-715.
    • (2007) Genes, Chromosomes & Cancer , vol.46 , pp. 708-715
    • Tirado, Y.1    Williams, M.D.2    Hanna, E.Y.3    Kaye, F.J.4    Batsakis, J.G.5    El-Naggar, A.K.6
  • 56
    • 67449105053 scopus 로고    scopus 로고
    • Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells
    • Yuan J., Liu X., Wu A., McGonagill P., Keller M., Galle C., Meier J. Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells. Journal of Virology 2009, 83:6391-6403.
    • (2009) Journal of Virology , vol.83 , pp. 6391-6403
    • Yuan, J.1    Liu, X.2    Wu, A.3    McGonagill, P.4    Keller, M.5    Galle, C.6    Meier, J.7
  • 57
    • 84859575891 scopus 로고    scopus 로고
    • HCMV-encoded UL128 enhances TNF-α and IL-6 expression and promotes PBMC proliferation through the MAPK/ERK pathway in vitro
    • Zheng Q., Tao R., Gao H., Xu J., Shang S., Zhao N. HCMV-encoded UL128 enhances TNF-α and IL-6 expression and promotes PBMC proliferation through the MAPK/ERK pathway in vitro. Viral Immunology 2012, 25:98-105.
    • (2012) Viral Immunology , vol.25 , pp. 98-105
    • Zheng, Q.1    Tao, R.2    Gao, H.3    Xu, J.4    Shang, S.5    Zhao, N.6


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