CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer

Gene Expression Patterns

Volumn 11, Issue 1-2, 2011, Pages 57-63

  Jaskoll, Tina ^a   Htet, Khine ^a   Abichaker, George ^a   Kaye, Frederic J ^b   Melnick, Michael ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cell proliferation; CREB coactivator; CRTC1; Development; Mucoepidermoid carcinoma; Salivary glands; Tumorigenesis

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CRTC1; UNCLASSIFIED DRUG;

ACINAR CELL CARCINOMA; ADENOSQUAMOUS CARCINOMA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; GENE EXPRESSION; HISTOPATHOLOGY; MORPHOGENESIS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SALIVARY GLAND CARCINOMA; SUBMANDIBULAR GLAND; TUMOR DIFFERENTIATION;

ANIMALS; CARCINOMA, MUCOEPIDERMOID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; SALIVARY GLAND NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 78751529619     PISSN: 1567133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gep.2010.09.003     Document Type: Article

References (24)

1. P.L. Auclair, and G.L. Ellis Mucoepidermoid carcinoma G.L. Ellis, P.L. Auclair, D.R. Gnepp, Surgical Pathology of the Salivary Gland 1991 W.B. Saunders Company Philadelphia 269 298
2. A. Behboudi, F. Enlund, M. Winnes, Y. Andrén, A. Nordkvist, I. Leivo, E. Flaberg, L. Szekely, A. Makitie, R. Grenman, J. Mark, and G. Stenman Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene Genes Chromosomes Cancer 45 2006 470 481
3. M.A. Bittinger, E. McWhinnie, J. Meltzer, V. Iourgenko, B. Latario, X. Liu, C.H. Chen, C. Song, D. Garza, and M. Labow Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins Curr. Biol. 14 2004 2156 2161 (Pubitemid 39623199)
4. G. Canettieri, S. Coni, M.D. Guardia, V. Nocerino, L. Antonucci, L. Di Magno, R. Screaton, I. Screpanti, G. Giannini, and A. Gulino The coactivator CRTC1 promotes cell proliferation and transformation via AP-1 Proc. Natl. Acad. Sci. USA 106 2009 1445 1450
5. M.D. Conkright, G. Canettieri, R. Screaton, E. Guzman, L. Miraglia, J.B. Hogenesch, and M. Montminy TORCs: transducers of regulated CREB activity Mol. Cell. 12 2003 413 423 (Pubitemid 37238928)
6. A. Coxon, W. Rozenblum, Y.S. Park, N. Joshi, J. Tsurutani, P.A. Dennis, I.R. Kirsch, and F.J. Kaye Mect1-Maml2 fusion oncogene linked to the aberrant activation of cyclic AMP/CREB regulated genes Cancer Res. 65 2005 7137 7144 (Pubitemid 41161243)
7. F. Enlund, A. Behboudi, Y. Andrén, C. Oberg, U. Lendahl, J. Mark, and G. Stenman Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors Exp. Cell Res. 292 2004 21 28 (Pubitemid 38058260)
8. E.W. Gresik Postnatal developmental changes in submandibular glands of rats and mice J. Histochem. Cytochem. 28 1980 860 870 (Pubitemid 11253575)
9. V. Iourgenko, W. Zhang, C. Mickanin, I. Daly, C. Jiang, J.M. Hexham, A.P. Orth, L. Miraglia, J. Meltzer, D. Garza, G.W. Chirn, E. McWhinnie, D. Cohen, J. Skelton, R. Terry, Y. Yu, D. Bodian, F.P. Buxton, J. Zhu, C. Song, and M.A. Labow Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells Proc. Natl. Acad. Sci. 100 2003 12147 12152 (Pubitemid 37271529)
10. T. Jaskoll, and M. Melnick Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations Anat. Rec. 256 1999 252 268 (Pubitemid 29506277)
11. T. Jaskoll, and M. Melnick Embryonic salivary gland branching morphogenesis J. Davies, Branching Morphogenesis 2005 Landes Bioscience/Eureka Press Georgetown 160 175
12. F.J. Kaye Emerging biology of malignant salivary gland tumors offers new insights into the classification and treatment of mucoepidermoid cancer Clin. Cancer Res. 12 2006 3878 3881 (Pubitemid 44078069)
13. F.J. Kaye Mutation-associated fusion cancer genes in solid tumors Mol. Cancer. Ther. 8 2009 6
14. T. Komiya, A.B. Coxon, Y. Park, W.D. Chen, M. Zajac-Kaye, P. Meltzer, T. Karpova, and F.J. Kaye Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer Oncogene 29 2010 1672 1680
15. T. Komiya, Y. Park, S. Modi, A.B. Coxon, H. Oh, and F.J. Kaye Sustained expression of Mext1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation Oncogene 25 2005 6128 6132 (Pubitemid 44562411)
16. M. Melnick, and T. Jaskoll Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing Crit. Rev. Oral Biol. 11 2000 189 215
17. M. Melnick, E.S. Mocarski, G. Abichaker, J. Huang, and T. Jaskoll Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model BMC Dev. Biol. 6 2006 42
18. M. Melnick, R.D. Phair, S.A. Lapidot, and T. Jaskoll Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm BMC Dev. Biol. 9 2009 32
19. T. Nakayama, S. Miyabe, M. Okabe, H. Sakuma, K. Ijichi, Y. Hasegawa, H. Nagatsuka, K. Shimozato, and H. Inagaki Clinicopathologcial significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma Mod. Pathol. 22 2009 1575 1581
20. M. Okabe, S. Miyabe, H. Nagtsuka, A. Terada, N. Hanai, M. Yokoi, K. Shimozato, T. Eimoto, S. Nakamura, N. Nagai, Y. Hasegawa, and H. Inagaki Mect1-Maml2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma Clin. Cancer Res. 12 2006 3902 3907 (Pubitemid 44078073)
21. I.D. O'Neill T(11;19) translocation and CRTC1-MAML2 fusion oncogene in mucoepidermoid carcinoma Oral Oncol. 45 2009 2 9
22. G. Stenman Fusion oncogenes and tumor type specificity-insights from salivary gland tumors Semin. Cancer. Biol. 15 2005 224 235
23. G. Tonon, S. Modi, L. Wu, A. Kubo, A.B. Coxon, T. Komiya, K. O'Neil, K. Stover, A. El-Naggar, J.D. Griffin, I.R. Kirsch, and F.J. Kaye T(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway Nat. Genet. 33 2003 208 430
24. L. Wu, J. Liu, P. Gao, M. Nakamura, Y. Cao, H. Shen, and J.D. Griffin Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation EMBO J. 24 2005 2391 2402 (Pubitemid 41032590)