Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury

Clinical Journal of the American Society of Nephrology

Volumn 5, Issue 12, 2010, Pages 2154-2165

  Koyner, Jay L ^a   Vaidya, Vishal S ^b   Bennett, Michael R ^c   Ma, Qing ^c   Worcester, Elaine ^a   Akhter, Shahab A ^a   Raman, Jai ^a   Jeevanandam, Valluvan ^a   O'Connor, Micheal F ^a   Devarajan, Prasad ^c   Bonventre, Joseph V ^b   Murray, Patrick T ^d  

^a UNIVERSITY OF CHICAGO   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYSTATIN C; GLUTATHIONE TRANSFERASE ALPHA; GLUTATHIONE TRANSFERASE P1; KIDNEY INJURY MOLECULE 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; SCATTER FACTOR; SODIUM; UREA;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CREATININE URINE LEVEL; FEMALE; HEART SURGERY; HUMAN; KIDNEY INJURY; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROGNOSIS; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SODIUM URINE LEVEL;

ACUTE KIDNEY INJURY; ACUTE-PHASE PROTEINS; AGED; AREA UNDER CURVE; BIOLOGICAL MARKERS; CYSTATIN C; EARLY DIAGNOSIS; FEMALE; GLUTATHIONE TRANSFERASE; HEPATOCYTE GROWTH FACTOR; HUMANS; LIPOCALINS; MALE; MEMBRANE GLYCOPROTEINS; PROGNOSIS; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS; RECEPTORS, VIRUS; ROC CURVE;

EID: 78649658970     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.00740110     Document Type: Article

References (46)

1. Wijeysundera DN, Karkouti K, Dupuis JY, Rao V, Chan CT, Granton JT, Beattie WS: Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery. JAMA 297: 1801-1809, 2007
2. Abel R, Buckley M, Austen W, Barnett G, Beck CJ, Fishcer J: Etiology, incidence and prognosis of renal failure following cardiac operations. Results of a prospective analysis of 500 consecutive patients. J Thorac Cardiovasc Surg 71: 323-333, 1976
3. Andersson L, Ekroth R, Bratteby L: Acute renal failure after coronary surgery: A study of incidence and risk factors in 2009 consecutive patients. Thorac Cardiovasc Surg 41: 237-241, 1993
4. Chertow G, Levy E, Hammermeister K, Grover F, Daley J: Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 104: 343-348, 1998 (Pubitemid 28211024)
5. Conlon P, Strafford-Smith M, WD W: Acute renal failure following cardiac surgery. Nephrol Dial Transplant 14: 1158-1162, 1999 (Pubitemid 29209301)
6. Mangano C, Diamondstone L, Ramsey J, Aggarwal A, Herskowitz A, Mangano D: Renal dysfunction after myocardial revascularization: Risk factors, adverse outcomes, and hospital resource utilization. Ann Intern Med 128: 194-203, 1998 (Pubitemid 28078200)
7. Ostermann M, Taube D, Morgan C, Evans T: Acute renal failure following cardiopulmonary bypass: A changing picture. Intensive Care Med 26: 565-571, 2000 (Pubitemid 30325873)
8. Tuttle K, Worrall N, Dahlstrom L, Nandagopal R, Kausz A, Davis C: Predictors of ARF after cardiac surgical procedures. Am J Kid Dis 41: 76-83, 2003 (Pubitemid 36043353)
9. Zanardo G, Michielon P, Paccagnella A: Acute renal failure in the patient undergoing cardiac operation: Prevalence, mortality rate, and main risk factors. J Thorac Cardiovasc Surg 107: 1489-1495, 1994 (Pubitemid 24184992)
10. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P: Acute renal failure - Definition, outcome measures, animal models, fluid therapy and information technology needs: The Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8: R204-R212, 2004
11. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A: Acute Kidney Injury Network: Report of an initiative to improve outcomes in acute kidney injury. Crit Care 11: R31, 2007 (Pubitemid 46604959)
12. Coca SG, Yalavarthy R, Concato J, Parikh CR: Biomarkers for the diagnosis and risk stratification of acute kidney injury: A systematic review. Kidney Int 73: 1008-1016, 2007
13. Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV: Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci 1: 200-208, 2008 (Pubitemid 352831522)
14. Parikh CR, Devarajan P: New biomarkers of acute kidney injury. Crit Care Med 36[4 Suppl]: S159-S165, 2008 (Pubitemid 351483046)
15. Han W, Bonventre J: Biological markers for the early detection of acute kidney injury. Curr Opin Crit Care 10: 476-482, 2004 (Pubitemid 39620197)
16. Haase-Fielitz A, Bellomo R, Devarajan P, Story D, Matalanis G, Dragun D, Haase M: Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery - A prospective cohort study. Crit Care Med 37: 553-560, 2009
17. Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff S, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P: Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365: 1231-1238, 2005 (Pubitemid 40469655)
18. Han WK, Wagener G, Zhu Y, Wang S, Lee HT: Urinary biomarkers in the early detection of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol 4: 873-882, 2009
19. Koyner JL, Bennett MR, Worcester EM, Ma Q, Raman J, Jeevanandam V, Kasza KE, Connor MF, Konczal DJ, Trevino S, Devarajan P, Murray PT: Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 74: 1059-1069, 2008
20. Wagener G, Jan M, Kim M, Mori K, Barasch JM, Sladen RN, Lee HT: Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology 105: 485-491, 2006 (Pubitemid 44310430)
21. Liangos O, Tighiouart H, Perianayagam MC, Kolyada A, Han WK, Wald R, Bonventre JV, Jaber BL: Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass. Biomarkers 14: 423-431, 2009
22. Parikh CR, Mishra J, Thiessen-Philbrook H, Dursun B, Ma Q, Kelly C, Dent C, Devarajan P, Edelstein CL: Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. Kidney Int 70: 199-203, 2006 (Pubitemid 44000139)
23. Yavuz I, Asgun FH, Bolcal C, Bingol H, Yokusoglu M, Baysan O, Ozgurtas T, Demirkilic U, Tatar H: Importance of urinary measurement of glutathione S-transferase in renal dysfunction patients after on- and off-pump coronary artery bypass surgery. Thorac Cardiovasc Surg 57: 125-129, 2009
24. da Silva Magro MC, de Fatima Fernandes Vattimo M: Does urinalysis predict acute renal failure after heart surgery? Ren Fail 26: 385-392, 2004 (Pubitemid 39167615)
25. Perazella MA, Coca SG, Kanbay M, Brewster UC, Parikh CR: Diagnostic value of urine microscopy for differential diagnosis of acute kidney injury in hospitalized patients. Clin J Am Soc Nephrol 3: 1615-1619, 2008
26. Hilberman M, Myers BD, Carrie BJ, Derby G, Jamison RL, Stinson EB: Acute renal failure following cardiac surgery. J Thorac Cardiovasc Surg 77: 880-888, 1979 (Pubitemid 10208456)
27. Steiner RW: Interpreting the fractional excretion of sodium. Am J Med 77: 699-702, 1984
28. Fahimi D, Mohajeri S, Hajizadeh N, Madani A, Esfahani ST, Ataei N, Mohsseni P, Honarmand M: Comparison between fractional excretions of urea and sodium in children with acute kidney injury. Pediatr Nephrol 24: 2409-2412, 2009
29. Pepin MN, Bouchard J, Legault L, Ethier J: Diagnostic performance of fractional excretion of urea and fractional excretion of sodium in the evaluations of patients with acute kidney injury with or without diuretic treatment. Am J Kidney Dis 50: 566-573, 2007
30. Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV: Kidney injury molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury. Kidney Int 62: 237-244, 2002
31. Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, Yang J, Barasch J, Devarajan P: Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 14: 2534-2543, 2003
32. McIlroy DR, Wagener G, Lee HT: Neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery: The effect of baseline renal function on diagnostic performance. Clin J Am Soc Nephrol 5: 211-219, 2010
33. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D: A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 130: 461-470, 1999
34. Westhuyzen J, Endre ZH, Reece G, Reith DM, Saltissi D, Morgan TJ: Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol Dial Transplant 18: 543-551, 2003
35. DeLong ER, DeLong DM, Clarke-Pearson DL: Comparing the areas under two or more correlated receiver operating characteristic curves: A nonparametric approach. Biometrics 44: 837-845, 1988
36. Haase M, Bellomo R, Story D, Davenport P, Haase-Fielitz A: Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: A prospective observational cohort study. Crit Care 12: R96, 2008
37. Han WK, Waikar SS, Johnson A, Betensky RA, Dent CL, Devarajan P, Bonventre JV: Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int 73: 863-869, 2007
38. Herget-Rosenthal S, Marggraf G, Husing J, Goring F, Pietruck F, Janssen O, Philipp T, Kribben A: Early detection of acute renal failure by serum cystatin C. Kidney Int 66: 1115-1122, 2004
39. Parikh CR, Jani A, Mishra J, Ma Q, Kelly C, Barasch J, Edelstein CL, Devarajan P: Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant 6: 1639-1645, 2006
40. Zappitelli M, Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, Parikh CR, Goldstein SL: Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: A prospective cohort study. Crit Care 11: R84, 2007 (Pubitemid 47262102)
41. Pickering JW, Frampton CM, Endre ZH: Evaluation of trial outcomes in acute kidney injury by creatinine modeling. Clin J Am Soc Nephrol 4: 1705-1715, 2009
42. Harrison DJ, Kharbanda R, Cunningham DS, McLellan LI, Hayes JD: Distribution of glutathione S-transferase isoenzymes in human kidney: Basis for possible markers of renal injury. J Clin Pathol 42: 624-628, 1989 (Pubitemid 19156433)
43. Haase M, Bellomo R, Devarajan P, Ma Q, Bennett MR, Mockel M, Matalanis G, Dragun D, Haase-Fielitz A: Novel biomarkers early predict the severity of acute kidney injury after cardiac surgery in adults. Ann Thorac Surg 88: 124-130, 2009
44. Herget-Rosenthal S, Poppen D, Husing J, Marggraf G, Pietruck F, Jakob H, Philipp T, Kribben A: Prognostic value of tubular proteinuria and enzymuria in nonoliguric acute tubular necrosis. Clin Chem 50: 522-558, 2004 (Pubitemid 38297305)
45. Hall IE, Yarlagadda SG, Coca SG, Wang Z, Doshi M, Devarajan P, Han WK, Marcus RJ, Parikh CR: IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation. J Am Soc Nephrol 21: 189-197, 2009
46. Grenier FC, Ali S, Syed H, Workman R, Martens F, Liao M, Wang Y, Wong PY: Evaluation of the ARCHITECT urine NGAL assay: Assay performance, specimen handling requirements and biological variability. Clin Biochem 43: 615-620, 2009