Small increases in the urinary excretion of glutathione S-transferase A1 and P1 after cardiac surgery are not associated with clinically relevant renal injury

Intensive Care Medicine

Volumn 31, Issue 5, 2005, Pages 664-667

  Eijkenboom, Jos J A ^a   Van Eijk, Lucas T G J ^a   Pickkers, Peter ^a   Peters, Wilbert H M ^a   Wetzels, Jack F M ^a   Van Der Hoeven, Hans G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Acute renal failure; Cardiopulmonary bypass; Glutathione S transferases; Tubular markers; Urinary excretion

Indexed keywords

CREATININE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE P1; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART SURGERY; HUMAN; INTENSIVE CARE UNIT; KIDNEY FUNCTION; KIDNEY TUBULE DAMAGE; MAJOR CLINICAL STUDY; MALE; OBSERVATION; POSTOPERATIVE PERIOD; PREDICTION; URINARY EXCRETION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARDIAC SURGICAL PROCEDURES; CREATININE; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; KIDNEY FAILURE, ACUTE; MALE; MIDDLE AGED; OBSERVATION; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 18844380757     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-005-2608-2     Document Type: Article

References (15)

1. Bouman C, Kellum JA, Lameire N, Levin N (2004) Acute dialysis quality initiative. Definitions of acute renal failure. http://www.anes.upmc.edu/ mcctp/adqi02.html
2. Chertow GM, Levy EM, Hammermeister KE, Grover F, Daley J (1998) Independent association between acute renal failure and mortality following cardiac surgery. Am J Med 104:343-348
3. Block CA, Manning HL (2002) Prevention of acute renal failure in the critically ill. Am J Respir Crit Care Med 165:320-324
4. Chertow GM, Lazarus JM, Christiansen CL, Cook EF, Hammermeister KE, Grover F, Daley J (1997) Preoperative renal risk stratification. Circulation 95:878-884
5. Hamada Y, Kanda T, Anzai T, Kobayashi I, Morishita Y (1999) N-acetyl-beta-D-glucosaminidase is not a predictor, but an indicator of kidney injury in patients with cardiac surgery. J Med 30:329-336
6. Mannervik B, Alin P, Guthenberg C, Jensson H, Tahir MK, Warholm M, Jornvall H (1985) Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A 82:7202-7206
7. Harrison DJ, Kharbanda R, Cunningham DS, McLellan LI, Hayes JD (1989) Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury. J Clin Pathol 42:624-628
8. Westhuyzen J, Endre ZH, Reece G, Reith DM, Saltissi D, Morgan TJ (2003) Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol Dial Transplant 18:543-551
9. Piper SN, Kumle B, Maleck WH, Kiessling AH, Lehmann A, Rohm KD, Suttner SW, Boldt J (2003) Diltiazem may preserve renal tubular integrity after cardiac surgery. Can J Anaesth 50:285-292
10. Boldt J, Brenner T, Lehmann A, Lang J, Kumle B, Werling C (2003) Influence of two different volume replacement regimens on renal function in elderly patients undergoing cardiac surgery: comparison of a new starch preparation with gelatin. Intensive Care Med 29:763-769
11. Mulder TP, Peters WH, Court DA, Jansen JB (1996) Sandwich ELISA for glutathione S-transferase Alpha 1-1: plasma concentrations in controls and in patients with gastrointestinal disorders. Clin Chem 42:416-419
12. Mulder TP, Peters WH, Wobbes T, Witteman BJ, Jansen JB (1997) Measurement of glutathione S-transferase P1-1 in plasma: pitfalls and significance of screening and follow-up of patients with gastrointestinal carcinoma. Cancer 80:873-880
13. Branten AJ, Mulder TP, Peters WH, Assmann KJ, Wetzels JF (2000) Urinary excretion of glutathione S transferases alpha and pi in patients with proteinuria: reflection of the site of tubular injury. Nephron 85:120-126
14. Sarvary E, Nemes B, Jaray J, Dinya E, Borka P, Varga M, Sulyok B, Remport A, Toth A, Perner F (2000) Prediction of early renal graft function by the measurement of donor urinary glutathione S-transferases. Transplantation 69:1397-1402
15. Cressey G, Roberts DR, Snowden CP (2002) Renal tubular injury after infrarenal aortic aneurysm repair. J Cardiothorac Vasc Anesth 16:290-293