The predictive performance of plasma neutrophil gelatinase-associated lipocalin (NGAL) increases with grade of acute kidney injury

Nephrology Dialysis Transplantation

Volumn 24, Issue 11, 2009, Pages 3349-3354

  Haase Fielitz, Anja ^a,b   Bellomo, Rinaldo ^a   Devarajan, Prasad ^c   Bennett, Michael ^c   Story, David ^a   Matalanis, George ^a   Frei, Ulrich ^b   Dragun, Duska ^b   Haase, Michael ^a,b  

^a AUSTIN HEALTH   (Australia)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Acute kidney injury; Cardiac surgery; Grade; Neutrophil gelatinase associated lipocalin (NGAL); RIFLE

Indexed keywords

CREATININE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; ACUTE PHASE PROTEIN; LCN2 PROTEIN, HUMAN; LIPOCALIN; ONCOPROTEIN;

AGED; ARTICLE; COMORBIDITY; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; HEART PERFORMANCE; HUMAN; HYPERTENSION; KIDNEY INJURY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ACUTE KIDNEY FAILURE; ADULT; AREA UNDER THE CURVE; BLOOD; CLASSIFICATION; HEART SURGERY; MIDDLE AGED; PREDICTION AND FORECASTING; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC;

ACUTE-PHASE PROTEINS; ADULT; AGED; AREA UNDER CURVE; CARDIAC SURGICAL PROCEDURES; CREATININE; FEMALE; HUMANS; KIDNEY FAILURE, ACUTE; LIPOCALINS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS; ROC CURVE;

EID: 73949148024     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp234     Document Type: Article

References (20)

1. Mishra J, Dent C, Tarabishi R et al. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005; 365: 1231-1238
2. Parikh CR, Jani A, Mishra J et al. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant 2006; 6: 1639-1645
3. Nickolas TL, O'Rourke MJ, Yang J et al. Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury. Ann Intern Med 2008; 148: 810-819
4. Dent CL, Ma Q, Dastrala S et al. Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care 2007; 11: R127
5. Bennett M, Dent CL, Ma Q et al. Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study. Clin J Am Soc Nephrol 2008; 3: 665-673
6. Wagener G, Jan M, Kim M et al. Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute kidney injury after adult cardiac surgery. Anesthesiology 2006; 105: 485-491
7. Wagener G, Gubitosa G, Wang S et al. Urinary neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery. Am J Kidney Dis 2008; 52: 425-433
8. Koyner JL, Bennett MR, Worcester EM et al. Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery. Kidney Int 2008; 74: 1059-1069
9. Haase-Fielitz A, Bellomo R, Devarajan P et al. Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery-a prospective cohort study. Crit Care Med 2009; 37: 553-560
10. Bellomo R, Ronco C, Kellum JA et al. Acute renalfailure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004; 8: R204-212
11. Mehta RL, Kellum JA, Shah SV et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11: R31
12. Devarajan P. NGAL in acute kidney injury: from serendipity to utility. Am J Kidney Dis 2008; 52: 395-399
13. Levey AS, Coresh J, Greene T et al. Expressing the modification of diet in renal disease study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin Chem 2007; 53: 766-772
14. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983; 148: 839-843
15. Nashef SA, Roques F, Michel P et al. European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 1999; 16: 9-13
16. Axelsson L, Bergenfeldt M, Ohlsson K. Studies of the release and turnover of a human neutrophil lipocalin. Scand J Clin Lab Invest 1995; 55: 577-588
17. Haase M, Haase-Fielitz A, Bagshaw SM et al. A phase II randomized controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients. Crit Care Med 2007; 35: 1324-1331
18. Swets JA. Measuring the accuracy of diagnostic systems. Science 1988; 240: 1285-1293
19. Schmidt-Ott KM, Mori K, Li JY et al. Dual action of neutrophil gelatinase-associated lipocalin. J Am Soc Nephrol 2007; 18: 407-413
20. Portilla D, Dent C, Sugaya T et al. Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery. Kidney Int 2008; 73: 465-472