Oxygen glucose deprivation causes mitochondrial dysfunction in cultivated rat hippocampal slices: Protective effects of CsA, its immunosuppressive congener [D-Ser]8CsA, the novel non-immunosuppressive cyclosporin derivative Cs9, and the NMDA receptor antagonist MK 801

Mitochondrion

Volumn 13, Issue 5, 2013, Pages 539-547

  Trumbeckaite, Sonata ^f   Gizatullina, Zemfira ^a   Arandarcikaite, Odeta ^f   Röhnert, Peter ^d   Vielhaber, Stefan ^b,c   Malesevic, Miroslav ^e   Fischer, Gunter ^e   Seppet, Enn ^g   Striggow, Frank ^c   Gellerich, Frank Norbert ^a,b  

^a LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d European ScreeningPort GmbH   (Germany)

^e MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^f LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

^g UNIVERSITY OF TARTU   (Estonia)

Author keywords

Cs9; Mitochondria; Organotypic hippocampal slice cultures; Oxygen glucose deprivation

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN 9; CYCLOSPORIN A [DEXTRO SERINE]; CYCLOSPORIN DERIVATIVE; CYTOCHROME C; DIZOCILPINE; GLUCOSE; GLUTAMIC ACID; MALIC ACID; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN PERFUSION; BRAIN SLICE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; MALE; MITOCHONDRIAL RESPIRATION; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

RATTUS;

(MMF); 5,5′-DITHIOBIS-(2-NITROBENZOIC ACID); BCA; BICINCHONINIC ACID; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CITRATE SYNTHASE; CPEO; CS; CS9; DTNB; MITOCHONDRIA; MITOCHONDRIAL MAIN FUNCTION; N-METHYL-D-ASPARTATE; NMDA; OGD; ORGANOTYPIC HIPPOCAMPAL SLICE CULTURES; ORGANOTYPIC HIPPOCAMPAL SLICES; OXYGEN/GLUCOSE DEPRIVATION; PERMEABILITY TRANSITION; PI; PROPIDIUM IODIDE; PT; RCI; RESPIRATORY CONTROL INDICES; SD; SLICES; STANDARD DEVIATION;

ANIMALS; CELL RESPIRATION; CYCLOSPORINS; DIZOCILPINE MALEATE; GLUCOSE; HIPPOCAMPUS; MALE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; OXYGEN; RATS; RATS, WISTAR;

EID: 84874501869     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2012.07.110     Document Type: Article

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