Impaired regulation of brain mitochondria by extramitochondrial Ca 2+ in transgenic huntington disease rats

Journal of Biological Chemistry

Volumn 283, Issue 45, 2008, Pages 30715-30724

  Gellerich, Frank N ^a   Gizatullina, Zemfira ^a   Nguyen, Huu P ^b   Trumbeckaite, Sonata ^c   Vielhaber, Stefan ^d   Seppet, Enn ^e   Zierz, Stephan ^f   Landwehrmeyer, Bernhard ^g   Riess, Olaf ^b   Von Hörsten, Stephan ^h   Striggow, Frank ^a,i  

^a KeyNeurotek AG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

^e UNIVERSITY OF TARTU   (Estonia)

^f MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^g UNIVERSITY OF ULM   (Germany)

^h UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

ⁱ KeyNeurotek Pharmaceuticals AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; CELL DEATH; CELL MEMBRANES; LAWS AND LEGISLATION; MITOCHONDRIA; PHOTOTRANSISTORS; RATS; RUTHENIUM; SUBSTRATES;

BRAIN MITOCHONDRION; CA FREE; CYCLOSPORIN; DYSREGULATION; HUNTINGTIN; HUNTINGTON DISEASES; MEMBRANE POTENTIALS; PATHOMECHANISMS; PERMEABILITY TRANSITIONS; POLYGLUTAMINE; TRANSGENIC; WILD TYPES;

CALCIUM;

CALCIUM; CYCLOSPORIN A; GLUTAMIC ACID; GLUTAMINE; MALIC ACID; PYRUVIC ACID; RUTHENIUM RED;

ANIMAL TISSUE; ARTICLE; ATROPHY; BRAIN MITOCHONDRION; CELL DEATH; COMPARATIVE STUDY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; HUNTINGTON CHOREA; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; TRANSGENIC RAT; WILD TYPE;

ANIMALS; BRAIN; CALCIUM; CELL DEATH; COLORING AGENTS; CYCLOSPORINE; ENERGY METABOLISM; ENZYME INHIBITORS; HUMANS; HUNTINGTON DISEASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; OXYGEN CONSUMPTION; RATS; RATS, TRANSGENIC; RUTHENIUM RED;

RATTUS;

EID: 57649158657     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709555200     Document Type: Article

References (50)

1. Ambrose, C. M., Duyao, M. P., Barnes, G., Bates, G. P., Lin, C. S., Srinidhi, J., Baxendale, S., Hummerich, H., Lehrach, H., and Altherr, M. (1994) Somat. Cell Mol. Genet. 20, 27-38
2. Li, S. H. L., Schilling, G., Young, W. S., III, Li, X. J., Margolis, R. L., Stine, O. C., Wagster, M. V., Abbott, M. H., Franz, M. L., Ranen, N. G., Folstein, S. E., Hedreen, J. C., and Ross, C. A. (1993) Neuron 11, 985-993
3. Langbehn, D. R., Brinkman, R. R., Falush, D., Paulsen, J. S., and Hayden, M. R. (2004) Clin. Genet. 65, 276-277
4. Harjes, P., and Wanker, E. E. (2003) Trends Biochem. Sci. 28, 425-433
5. Browne, S. E., and Beal, M. F. (2005) Neurochem. Res. 29, 531-546
6. Seppet, E., Gizatullina, Z., Trumbeckaite, S., Zierz, S., Striggow, F., and Gellerich, F. N. (2007) in Molecular System Bioenergetics, Energy for Life (Saks, V., ed) pp. 479-520, Wiley-VCH, Weinheim, Germany
7. Panov, A. V., Gutekunst, C. A., Leavitt, B. R., Hayden, M. R., Burke, J. R., Strittmatter, W. J., and Greenamyre, J. T. (2002) Nat. Neurosci. 5, 731-736
8. Gizatullina, Z. Z., Lindenberg, K. S., Harjes, P., Chen, Y., Kosinski, C. M., Landwehrmeyer, B. G., Ludolph, A. C., Striggow, F., Zierz, S., and Gellerich, F. N. (2006) Ann. Neurol. 59, 407-411
9. Choo, Y. S., Johnson, G. V., MacDonald, M., Detloff, P. J., and Lesort, M. (2004) Hum. Mol. Genet. 13, 1407-1420
10. Milakovic, T., Quintanilla, R. A., and Johnson, G. V. (2006) J. Biol. Chem. 281, 34785-34795
11. Rockabrand, E., Slepko, N., Pantalone, A., Nukala, V. N., Kazantsev, A., Marsh, J. L., Sullivan, P. G., Steffan, J. S., Sensi, S. L., and Thompson, L. M. (2007) Hum. Mol. Genet. 16, 61-77
12. Brustovetsky, N., LaFrance, R., Purl, K. J., Brustovetsky, T., Keene, C. D., Low, W. C., and Dubinsky, J. M. (2005) J. Neurochem. 93, 1361-1370
13. Oliveira, J. M., Jekabsons, M. B., Chen, S., Lin, A., Rego, A. C., Goncalves, J., Ellerby, L. M., and Nicholls, D. G. (2007) J. Neurochem. 101, 241-249
14. Kosinski, C. M., Schlangen, C., Gellerich, F. N., Gizatullina, Z., Deschauer, M., Schiefer, J., Young, A. B., Landwehrmeyer, G. B., Toyka, K. V., Sellhaus, B., and Lindenberg, K. S. (2007) Mov. Disord. 22, 637-640
15. Litsky, M. L., and Pfeiffer, D. R. (1997) Biochemistry 36, 7071-7080
16. Hansford, R. G., and Zorov, D. (1998) Mol. Cell. Biochem. 184, 359-369
17. Bernardi, P. (1992) J. Biol. Chem. 267, 8834-8839
18. Pardo, B., Contreras, L., Serrano, A., Ramos, M., Kobayashi, K., Iijima, M., Saheki, T., and Satrustegui, J. (2006) J. Biol. Chem. 281, 1039-1047
19. Palmieri, L., Pardo, B., Lasorsa, F. M., del Arco, A., Kobayashi, K., Iijima, M., Runswick, M. J., Walker, J. E., Saheki, T., Satrustegui, J., and Palmieri, F. (2001) EMBO J. 20, 5060-5069
20. von Hörsten, S., Schmitt, I., Nguyen, H. P., Holzmann, C., Schmidt, T., Walther, T., Bader, M., Pabst, R., Kobbe, P., Krotova, J., Stiller, D., Kask, A., Vaarmann, A, Rathke-Hartlieb, S., Schulz, J. B., Grasshoff, U., Bauer, I., Vieira-Saecker, A. M., Paul, M., Jones, L., Lindenberg, K. S., Landwehrmeyer, B., Bauer, A., Li, X. J., and Riess, O. (2003) Hum. Mol. Genet. 12, 617-624
21. Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S. W., and Bates, G. P. (1996) Cell 87, 493-506
22. Bezprozvanny, I., and Hayden, M. R. (2004) Biochem. Biophys. Res. Commun. 322, 1310-1317
23. Tang, T. S., Slow, E., Lupu, V., Stavrovscaya, I. G., Sugimori, M., Llinas, R., Kristal, B. S., Hayden, M. R., and Bezprozvanny, I. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 2602-2607
24. Gellerich, F. N., Trumbeckaite, S., Müller, T., Chen, Y., Deschauer, M., Gizatullina, Z., and Zierz, S. (2004) Mol. Cell. Biochem. 256/257, 391-405
25. Kudin, A. P., Bimpong-Buta, N. Y., Vielhaber, S., Elger, C. E., and Kunz, W. S. (2004) J. Biol. Chem. 279, 4127-4135
26. Gnaiger, E. (2001) Respir. Phys. 128, 277-297
27. Gizatullina, Z. Z., Chen, Y., Zierz, S., and Gellerich, F. N. (2005) Biochim. Biophys. Acta 706, 98-104
28. Groden, D. L., and Gvan, Z. Cell Calcium 12, 279-287
29. Uto, A., Arai, H., and Ogawa, Y. (1991) Cell Calcium 12, 29-37
30. Akerman, K. E., and Wikstrom, M. K. (1976) FEBS Lett. 68, 191-197
31. Wiechelman, K. J., Braun, R. D., and Fitzpatrick, J. D. (1988) Anal. Biochem. 175, 231-237
32. Schoolwerth, A. C., Nazar, B. L., and LaNoue, K. F. (1978) J. Biol. Chem. 253, 6177-6183
33. Schoolwerth, A. C., Hoover, W. J., Daniel, C. H., and Lanue, K. F. (1980) Int. J. Biochem. 12, 145-149
34. Hoek, J. B., Coll, K. E., and Williamson, J. R. (1983) J. Biol. Chem. 258, 54-58
35. Brustovetsky, N., and Dubinsky, J. M. (2000) J. Neurosci. 20, 8229-8237
36. Panov, A. V., Andreeva, L., and Greenamyre, J. T. (2004) Arch. Biochem. Biophys. 424, 44-52
37. Novgorodov, S. A., Gudz, T. I., Brierley, G. P., and Pfeiffer, D. R. (1994) Arch. Biochem. Biophys. 311, 219-228
38. Roesch, K., Hynds, P. J., Varga, R., Tranebjaerg, L., and Koehler, C. M. (2004) Hum. Mol. Genet. 13, 2101-2111
39. Mayr, J. A., Merkel, O., Kohlwein, S. D., Gebhardt, B. R., Bohles, H., Fotschl, U., Koch, J., Jaksch, M., Lochmuller, H., Horvath, R., Freisinger, P., and Sperl, W. (2007) Am. J. Hum. Genet. 80, 478-484
40. Panov, A. V., Burke, J. R., Strittmatter, W. J., and Greenamyre, J. T. (2003) Arch. Biochem. Biophys. 410, 1-6
41. Naga, K. K., Sullivan, P. G., and Geddes, J. W. (2007) J. Neurosci. 27, 7469-7475
42. Petrasch-Parwez, E., Nguyen, H. P., Lobbecke-Schumacher, M., Habbes, H. W., Wieczorek, S., Riess, O., Andres, K. H., Dermietzel, R., and von Horsten, S. (2007) J. Comp. Neurol. 501, 716-730
43. Bernardi, P., Veronese, P., and Petronilli, V. (1993) J. Biol. Chem. 268, 1005-1010
44. Kowaltowski, A. J., and Castilho, R. F. (1997) Biochim. Biophys. Acta 1322, 221-229
45. Nosek, M. T., Dransfield, D. T., and Aprille, J. R. (1990) J. Biol. Chem. 265, 8444-8450
46. Hagen, T., Lagace, C. J., Modica-Napolitano, J. S., and Aprille, J. R. (2003) Am. J. Physiol. 285, G274-G281
47. del Arco, A., and Satrustegui, J. (2004) J. Biol. Chem. 279, 24701-24713
48. Fiermonte, G., De Leonardis, F., Todisco, S., Palmieri, L., Lasorsa, F. M., and Palmieri, F. (2004) J. Biol. Chem. 279, 30722-30730
49. Igbavboa, U., and Pfeiffer, D. R. (1988) J. Biol. Chem. 263, 1405-1412
50. Bathori, G., Csordas, G., Garcia-Perez, C., Davies, E., and Hajnoczky, G. (2006) J. Biol. Chem. 281, 17347-17358