메뉴 건너뛰기




Volumn 11, Issue 3, 2011, Pages 421-429

Effects of cyclosporine A and its immunosuppressive or non-immunosuppressive derivatives [D-Ser]8-CsA and Cs9 on mitochondria from different brain regions

Author keywords

Cerebellum; Cortex; CsA derivatives; Cyclosporine A; Energy metabolism; Hippocampus; Mitochondria; Permeability transition pore; Striatum; Substantia nigra

Indexed keywords

CYCLOSPORIN A; CYCLOSPORIN A [8 DEXTRO O (2 HYDROXYETHYL)SERINE]; CYCLOSPORIN A DERIVATIVE;

EID: 79953764691     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2010.12.012     Document Type: Article
Times cited : (14)

References (45)
  • 1
    • 0032831667 scopus 로고    scopus 로고
    • Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver
    • Andreyev A., Fiskum G. Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver. Cell Death Differ. 1999, 6:825-832.
    • (1999) Cell Death Differ. , vol.6 , pp. 825-832
    • Andreyev, A.1    Fiskum, G.2
  • 2
    • 0022263019 scopus 로고
    • The temporal evolution of hypoglycemic brain damage. I. Light- and electron-microscopic findings in the rat cerebral cortex
    • Auer R.N., Kalimo H., Olsson Y., Siesjö B.K. The temporal evolution of hypoglycemic brain damage. I. Light- and electron-microscopic findings in the rat cerebral cortex. Acta Neuropathol. 1985, 67:13-24.
    • (1985) Acta Neuropathol. , vol.67 , pp. 13-24
    • Auer, R.N.1    Kalimo, H.2    Olsson, Y.3    Siesjö, B.K.4
  • 3
    • 33746081243 scopus 로고    scopus 로고
    • Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons
    • Bambrick L.L., Chandrasekaran K., Merabian Z., Wright C., Krueger B.K., Fiskum G. Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons. J. Bioenerg. Biomembr. 2006, 38:43-47.
    • (2006) J. Bioenerg. Biomembr. , vol.38 , pp. 43-47
    • Bambrick, L.L.1    Chandrasekaran, K.2    Merabian, Z.3    Wright, C.4    Krueger, B.K.5    Fiskum, G.6
  • 4
    • 0034535252 scopus 로고    scopus 로고
    • Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria
    • Berman S.B., Watkins S.C., Hastings T.G. Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria. Exp. Neurol. 2000, 164:415-425.
    • (2000) Exp. Neurol. , vol.164 , pp. 415-425
    • Berman, S.B.1    Watkins, S.C.2    Hastings, T.G.3
  • 5
    • 0024360271 scopus 로고
    • Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
    • Broekemeier K.M., Dempsey M.E., Pfeiffer D.R. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 1989, 264:7826-7830.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 6
    • 0034668844 scopus 로고    scopus 로고
    • Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria
    • Brustovetsky N., Dubinsky J.M. Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria. J. Neurosci. 2000, 20:8229-8237.
    • (2000) J. Neurosci. , vol.20 , pp. 8229-8237
    • Brustovetsky, N.1    Dubinsky, J.M.2
  • 9
    • 0038143180 scopus 로고    scopus 로고
    • The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria
    • Chalmers S., Nicholls D.G. The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J. Biol. Chem. 2003, 278:19062-19070.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19062-19070
    • Chalmers, S.1    Nicholls, D.G.2
  • 10
    • 0037891050 scopus 로고    scopus 로고
    • Cyclosporin A-insensitive permeability transition in brain mitochondria: inhibition by 2-aminoethoxydiphenyl borate
    • Chinopoulos C., Starkov A., Fiskum G. Cyclosporin A-insensitive permeability transition in brain mitochondria: inhibition by 2-aminoethoxydiphenyl borate. J. Biol. Chem. 2003, 278:27382-27389.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27382-27389
    • Chinopoulos, C.1    Starkov, A.2    Fiskum, G.3
  • 11
    • 0037144409 scopus 로고    scopus 로고
    • Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A
    • Clarke S.J., McStay G.P., Halestrap A.P. Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A. J. Biol. Chem. 2002, 277:34793-34799.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34793-34799
    • Clarke, S.J.1    McStay, G.P.2    Halestrap, A.P.3
  • 12
    • 1242351328 scopus 로고    scopus 로고
    • Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm
    • Domañska-Janik K., Buzañska L., Dłuzniewska J., Kozłowska H., Sarnowska A., Zabłocka B. Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm. Brain Res. Mol. Brain Res. 2004, 121:50-59.
    • (2004) Brain Res. Mol. Brain Res. , vol.121 , pp. 50-59
    • Domañska-Janik, K.1    Buzañska, L.2    Dłuzniewska, J.3    Kozłowska, H.4    Sarnowska, A.5    Zabłocka, B.6
  • 14
    • 0024959449 scopus 로고
    • Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
    • Fischer G., Wittmann-Liebold B., Lang K., Kiefhaber T., Schmid F.X. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 1989, 337:476-478.
    • (1989) Nature , vol.337 , pp. 476-478
    • Fischer, G.1    Wittmann-Liebold, B.2    Lang, K.3    Kiefhaber, T.4    Schmid, F.X.5
  • 15
    • 0032524667 scopus 로고    scopus 로고
    • Regulation of the permeability transition pore in skeletal muscle mitochondria
    • Fontanine E., Eriksson O., Ichas F., Bernardi P. Regulation of the permeability transition pore in skeletal muscle mitochondria. J. Biol. Chem. 1997, 273:12662-12668.
    • (1997) J. Biol. Chem. , vol.273 , pp. 12662-12668
    • Fontanine, E.1    Eriksson, O.2    Ichas, F.3    Bernardi, P.4
  • 16
    • 0033007651 scopus 로고    scopus 로고
    • Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability
    • Friberg H., Connern C., Halestrap A.P., Wieloch T. Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability. J. Neurochem. 1999, 72:2488-2497.
    • (1999) J. Neurochem. , vol.72 , pp. 2488-2497
    • Friberg, H.1    Connern, C.2    Halestrap, A.P.3    Wieloch, T.4
  • 20
    • 11144300814 scopus 로고    scopus 로고
    • Effects of extramitochondrial ADP on permeability transition of mouse liver mitochondria
    • Gizatullina Z.Z., Chen Y., Zierz S., Gellerich F.-N. Effects of extramitochondrial ADP on permeability transition of mouse liver mitochondria. Biochim. Biophys. Acta 2005, 706:98-104.
    • (2005) Biochim. Biophys. Acta , vol.706 , pp. 98-104
    • Gizatullina, Z.Z.1    Chen, Y.2    Zierz, S.3    Gellerich, F.-N.4
  • 21
    • 0035155343 scopus 로고    scopus 로고
    • Bioenergetics at low oxygen: dependence of respiration and phosphorylation on oxygen and adenosine diphosphate supply
    • Gnaiger E. Bioenergetics at low oxygen: dependence of respiration and phosphorylation on oxygen and adenosine diphosphate supply. Respir. Physiol. 2001, 128:277-297.
    • (2001) Respir. Physiol. , vol.128 , pp. 277-297
    • Gnaiger, E.1
  • 22
    • 0028968606 scopus 로고
    • Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion
    • Griffiths E.J., Halestrap A.P. Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem. J. 1995, 307:93-98.
    • (1995) Biochem. J. , vol.307 , pp. 93-98
    • Griffiths, E.J.1    Halestrap, A.P.2
  • 23
    • 0030826778 scopus 로고    scopus 로고
    • Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury
    • Halestrap A.P., Connern C.P., Griffiths E.J., Kerr P.M. Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol. Cell. Biochem. 1997, 174:167-172.
    • (1997) Mol. Cell. Biochem. , vol.174 , pp. 167-172
    • Halestrap, A.P.1    Connern, C.P.2    Griffiths, E.J.3    Kerr, P.M.4
  • 24
    • 2042520908 scopus 로고    scopus 로고
    • Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition
    • Hansson M.J., Mansson R., Mattiasson G., Ohlsson J., Karlsson J., Keep M.F., Elmer E. Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition. J. Neurochem. 2004, 89:715-729.
    • (2004) J. Neurochem. , vol.89 , pp. 715-729
    • Hansson, M.J.1    Mansson, R.2    Mattiasson, G.3    Ohlsson, J.4    Karlsson, J.5    Keep, M.F.6    Elmer, E.7
  • 25
    • 0028884932 scopus 로고
    • Cyclosporin analogs modified in the 3, 7, 8-positions: substituent effects on peptidylprolyl isomerase inhibition and immunosuppressive activity are nonadditive
    • Hu M.K., Badger A., Rich D.H. Cyclosporin analogs modified in the 3, 7, 8-positions: substituent effects on peptidylprolyl isomerase inhibition and immunosuppressive activity are nonadditive. J. Med. Chem. 1995, 38:4164-4170.
    • (1995) J. Med. Chem. , vol.38 , pp. 4164-4170
    • Hu, M.K.1    Badger, A.2    Rich, D.H.3
  • 26
    • 0032860116 scopus 로고    scopus 로고
    • Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons
    • Khaspekov L., Friberg H., Halestrap A.P., Viktorov I., Wieloch T. Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons. J. Neurosci. 1999, 11:3194-3198.
    • (1999) J. Neurosci. , vol.11 , pp. 3194-3198
    • Khaspekov, L.1    Friberg, H.2    Halestrap, A.P.3    Viktorov, I.4    Wieloch, T.5
  • 28
    • 0034090710 scopus 로고    scopus 로고
    • Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: effect of cyclosporin A and ubiquinone O
    • Kristian T., Gertsch J., Bates T.E., Siesjö B.K. Characteristics of the calcium-triggered mitochondrial permeability transition in nonsynaptic brain mitochondria: effect of cyclosporin A and ubiquinone O. J. Neurochem. 2000, 74:1999-2009.
    • (2000) J. Neurochem. , vol.74 , pp. 1999-2009
    • Kristian, T.1    Gertsch, J.2    Bates, T.E.3    Siesjö, B.K.4
  • 29
    • 0016512234 scopus 로고
    • Therapeutic use of diazoxide in a probable case of idiopathic hypoglycemia in an infant
    • Kubimura N., Irieda K., Ito J., Konno S. Therapeutic use of diazoxide in a probable case of idiopathic hypoglycemia in an infant. Horumon To Rinsho 1975, 23:609-613.
    • (1975) Horumon To Rinsho , vol.23 , pp. 609-613
    • Kubimura, N.1    Irieda, K.2    Ito, J.3    Konno, S.4
  • 32
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J., Farmer J.D., Lane W.S., Friedman J., Weissman I., Schreiber S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66:807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 33
    • 34447498864 scopus 로고    scopus 로고
    • High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition
    • Naga K.K., Sullivan P.G., Geddes J.W. High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition. J. Neurosci. 2007, 27:7469-7475.
    • (2007) J. Neurosci. , vol.27 , pp. 7469-7475
    • Naga, K.K.1    Sullivan, P.G.2    Geddes, J.W.3
  • 34
    • 0026742968 scopus 로고
    • The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A
    • Novgorodov S.A., Gudz T.I., Milgrom Y.M., Brierley G.P. The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. J. Biol. Chem. 1992, 267:16274-16282.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16274-16282
    • Novgorodov, S.A.1    Gudz, T.I.2    Milgrom, Y.M.3    Brierley, G.P.4
  • 35
    • 1542268971 scopus 로고    scopus 로고
    • Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria
    • Panov A.V., Andreeva L., Greenamyre J.T. Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria. Arch. Biochem. Biophys. 2004, 424:44-52.
    • (2004) Arch. Biochem. Biophys. , vol.424 , pp. 44-52
    • Panov, A.V.1    Andreeva, L.2    Greenamyre, J.T.3
  • 36
    • 0027508994 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore
    • Petronilli V., Cola C., Bernardi P. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. J. Biol. Chem. 1993, 268:1011-1016.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1011-1016
    • Petronilli, V.1    Cola, C.2    Bernardi, P.3
  • 37
    • 33846308531 scopus 로고    scopus 로고
    • Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
    • Purisai M.G., McCormack A.L., Cumine S., Li J., Isla M.Z., Di Monte D.A. Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiol. Dis. 2007, 25:392-400.
    • (2007) Neurobiol. Dis. , vol.25 , pp. 392-400
    • Purisai, M.G.1    McCormack, A.L.2    Cumine, S.3    Li, J.4    Isla, M.Z.5    Di Monte, D.A.6
  • 39
    • 0034057187 scopus 로고    scopus 로고
    • Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury
    • Sullivan P.G., Thompson M., Scheff S.W. Continuous infusion of cyclosporin A postinjury significantly ameliorates cortical damage following traumatic brain injury. Exp. Neurol. 2000, 161:631-637.
    • (2000) Exp. Neurol. , vol.161 , pp. 631-637
    • Sullivan, P.G.1    Thompson, M.2    Scheff, S.W.3
  • 40
    • 0021969569 scopus 로고
    • The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria
    • Vitorica J., Satrústegui J. The role of ADP in the modulation of the calcium-efflux pathway in rat brain mitochondria. Biochem. J. 1985, 225:41-49.
    • (1985) Biochem. J. , vol.225 , pp. 41-49
    • Vitorica, J.1    Satrústegui, J.2
  • 41
    • 0036088518 scopus 로고    scopus 로고
    • Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811
    • Waldmeier P.C., Feldtrauer J.-J., Qian T., Lemasters J.J. Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. Mol. Pharmacol. 2002, 62:22-29.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 22-29
    • Waldmeier, P.C.1    Feldtrauer, J.-J.2    Qian, T.3    Lemasters, J.J.4
  • 42
    • 0024289285 scopus 로고
    • Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation
    • Wiechelmann K., Braun R., Fitzpatrick J. Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation. Anal. Biochem. 1988, 175:231-237.
    • (1988) Anal. Biochem. , vol.175 , pp. 231-237
    • Wiechelmann, K.1    Braun, R.2    Fitzpatrick, J.3
  • 43
    • 0023186923 scopus 로고
    • ATP-metabolizing enzymes in suspensions of isolated coupled rat brain mitochondria
    • Wustmann C., Petzold D., Fischer H.D., Kunz W. ATP-metabolizing enzymes in suspensions of isolated coupled rat brain mitochondria. Biomed. Biochim. Acta 1987, 46:331-340.
    • (1987) Biomed. Biochim. Acta , vol.46 , pp. 331-340
    • Wustmann, C.1    Petzold, D.2    Fischer, H.D.3    Kunz, W.4
  • 44
    • 14244258607 scopus 로고    scopus 로고
    • Unexpected side chain effects at residue 8 of cyclosporin a derivatives allow photoswitching of immunosuppression
    • Zhang Y., Erdmann F., Baumgrass R., Schutkowski M., Fischer G. Unexpected side chain effects at residue 8 of cyclosporin a derivatives allow photoswitching of immunosuppression. J. Biol. Chem. 2005, 280:4842-4850.
    • (2005) J. Biol. Chem. , vol.280 , pp. 4842-4850
    • Zhang, Y.1    Erdmann, F.2    Baumgrass, R.3    Schutkowski, M.4    Fischer, G.5
  • 45
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zoratti M., Szabò I. The mitochondrial permeability transition. Biochim. Biophys. Acta 1995, 1241:139-176.
    • (1995) Biochim. Biophys. Acta , vol.1241 , pp. 139-176
    • Zoratti, M.1    Szabò, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.