-
1
-
-
68049098031
-
-
S. Wetzel, K. Klein, S. Renner, D. Rauh, T. I. Oprea, P. Mutzel, H. Waldmann, Nat. Chem. Biol. 2009, 5, 581
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 581
-
-
Wetzel, S.1
Klein, K.2
Renner, S.3
Rauh, D.4
Oprea, T.I.5
Mutzel, P.6
Waldmann, H.7
-
2
-
-
68049094985
-
-
S. Renner, W. A. L. van Otterlo, M. Dominguez Seoane, S. Möcklinghoff, B. Hofmann, S. Wetzel, A. Schuffenhauer, P. Ertl, T. I. Oprea, D. Steinhilber, L. Brunsveld, D. Rauh, H. Waldmann, Nat. Chem. Biol. 2009, 5, 585
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 585
-
-
Renner, S.1
Van Otterlo, W.A.L.2
Dominguez Seoane, M.3
Möcklinghoff, S.4
Hofmann, B.5
Wetzel, S.6
Schuffenhauer, A.7
Ertl, P.8
Oprea, T.I.9
Steinhilber, D.10
Brunsveld, L.11
Rauh, D.12
Waldmann, H.13
-
3
-
-
77249139237
-
-
Y. Hu, A. M. Wassermann, E. Lounkine, J. Bajorath, J. Med. Chem. 2010, 53, 752
-
(2010)
J. Med. Chem
, vol.53
, pp. 752
-
-
Hu, Y.1
Wassermann, A.M.2
Lounkine, E.3
Bajorath, J.4
-
4
-
-
33746156959
-
-
G. V. Paolini, R. H. B. Shapland, W. P. van Hoorn, J. S. Mason, A. L. Hopkins, Nat. Biotechnol. 2006, 24, 805
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 805
-
-
Paolini, G.V.1
Shapland, R.H.B.2
Van Hoorn, W.P.3
Mason, J.S.4
Hopkins, A.L.5
-
5
-
-
80855156740
-
-
S. Wetzel, R. S. Bon, K. Kumar, H. Waldmann, Angew. Chem., Int. Ed. 2011, 50, 10800
-
(2011)
Angew. Chem., Int. Ed
, vol.50
, pp. 10800
-
-
Wetzel, S.1
Bon, R.S.2
Kumar, K.3
Waldmann, H.4
-
6
-
-
0024239320
-
-
B. E. Evans, K. E. Rittle, M. G. Bock, R. M. DiPardo, R. M. Freidinger, W. L. Whitter, G. F. Lundell, D. F. Veber, P. S. Anderson, R. S. L. Chang, V. J. Lotti, D. J. Cerino, T. B. Chen, P. J. Kling, K. A. Kunkel, J. P. Springer, J. Med. Chem. 1988, 31, 2235
-
(1988)
J. Med. Chem
, vol.31
, pp. 2235
-
-
Evans, B.E.1
Rittle, K.E.2
Bock, M.G.3
Dipardo, R.M.4
Freidinger, R.M.5
Whitter, W.L.6
Lundell, G.F.7
Veber, D.F.8
Anderson, P.S.9
Chang, R.S.L.10
Lotti, V.J.11
Cerino, D.J.12
Chen, T.B.13
Kling, P.J.14
Kunkel, K.A.15
Springer, J.P.16
-
8
-
-
80052002666
-
-
Y. Hu, D. Stumpfe, J. Bajorath, J. Chem. Inf. Model. 2011, 51, 1742
-
(2011)
J. Chem. Inf. Model.
, vol.51
, pp. 1742
-
-
Hu, Y.1
Stumpfe, D.2
Bajorath, J.3
-
9
-
-
45249123879
-
-
A. H. Lipkus, Q. Yuan, K. A. Lucas, S. A. Funk, W. F. Bartelt, R. J. Schenck, A. J. Trippe, J. Org. Chem. 2008, 73, 4443
-
(2008)
J. Org. Chem
, vol.73
, pp. 4443
-
-
Lipkus, A.H.1
Yuan, Q.2
Lucas, K.A.3
Funk, S.A.4
Bartelt, W.F.5
Schenck, R.J.6
Trippe, A.J.7
-
10
-
-
33646242741
-
-
M. Krier, G. Bret, D. Rognan, J. Chem. Inf. Model. 2006, 46, 512
-
(2006)
J. Chem. Inf. Model.
, vol.46
, pp. 512
-
-
Krier, M.1
Bret, G.2
Rognan, D.3
-
11
-
-
82955213501
-
-
M. Dow, M. Fisher, T. James, F. Marchetti, A. Nelson, Org. Biomol. Chem. 2012, 10, 17
-
(2012)
Org. Biomol. Chem
, vol.10
, pp. 17
-
-
Dow, M.1
Fisher, M.2
James, T.3
Marchetti, F.4
Nelson, A.5
-
12
-
-
0037468884
-
-
M. C. Wenlock, R. P. Austin, P. Barton, A. M. Davis, P. D. Leeson, J. Med. Chem. 2003, 46, 1250
-
(2003)
J. Med. Chem
, vol.46
, pp. 1250
-
-
Wenlock, M.C.1
Austin, R.P.2
Barton, P.3
Davis, A.M.4
Leeson, P.D.5
-
15
-
-
71049126548
-
-
F. Lovering, J. Bikker, C. Humblet, J. Med. Chem. 2009, 52, 6752
-
(2009)
J. Med. Chem
, vol.52
, pp. 6752
-
-
Lovering, F.1
Bikker, J.2
Humblet, C.3
-
16
-
-
0035438391
-
-
T. I. Oprea, A. M. Davis, S. J. Teague, P. D. Leeson, J. Chem. Inf. Comput. Sci. 2001, 41, 1308
-
(2001)
J. Chem. Inf. Comput. Sci
, vol.41
, pp. 1308
-
-
Oprea, T.I.1
Davis, A.M.2
Teague, S.J.3
Leeson, P.D.4
-
18
-
-
84856134589
-
-
A. Nadin, C. Hattotuwagama, I. Churcher, Angew. Chem., Int. Ed. 2012, 51, 1114
-
(2012)
Angew. Chem., Int. Ed
, vol.51
, pp. 1114
-
-
Nadin, A.1
Hattotuwagama, C.2
Churcher, I.3
-
20
-
-
78249273274
-
-
T. W. J. Cooper, I. B. Campbell, S. J. F. Macdonald, Angew. Chem., Int. Ed. 2010, 49, 8082
-
(2010)
Angew. Chem., Int. Ed
, vol.49
, pp. 8082
-
-
Cooper, T.W.J.1
Campbell, I.B.2
Mac donald, S.J.F.3
-
21
-
-
37549020046
-
-
T. E. Nielsen, S. L. Schreiber, Angew. Chem., Int. Ed. 2008, 47, 48
-
(2008)
Angew. Chem., Int. Ed
, vol.47
, pp. 48
-
-
Nielsen, T.E.1
Schreiber, S.L.2
-
22
-
-
3042799070
-
-
M. D. Burke, S. L. Schreiber, Angew. Chem., Int. Ed. 2004, 43, 46
-
(2004)
Angew. Chem., Int. Ed
, vol.43
, pp. 46
-
-
Burke, M.D.1
Schreiber, S.L.2
-
23
-
-
84880296641
-
-
W. R. J. D. Galloway, A. Isidro-Llobet, D. R. Spring, Nat. Commun. 2010, 1, 80
-
(2010)
Nat. Commun
, vol.1
, pp. 80
-
-
Galloway, W.R.J.D.1
Isidro-Llobet, A.2
Spring, D.R.3
-
24
-
-
77949824264
-
-
A. Rolfe, T. B. Samarakoon, P. R. Hanson, Org. Lett. 2010, 12, 1216
-
(2010)
Org. Lett
, vol.12
, pp. 1216
-
-
Rolfe, A.1
Samarakoon, T.B.2
Hanson, P.R.3
-
25
-
-
33847074190
-
-
M. B. Bertrand, M. L. Leathen, J. P. Wolfe, Org. Lett. 2007, 9, 457
-
(2007)
Org. Lett
, vol.9
, pp. 457
-
-
Bertrand, M.B.1
Leathen, M.L.2
Wolfe, J.P.3
-
26
-
-
84860334008
-
-
H. Brice, D. M. Gill, L. Goldie, P. S. Keegan, W. J. Kerr, P. H. Svensson, Chem. Commun. 2012, 48, 4836
-
(2012)
Chem. Commun.
, vol.48
, pp. 4836
-
-
Brice, H.1
Gill, D.M.2
Goldie, L.3
Keegan, P.S.4
Kerr, W.J.5
Svensson, P.H.6
-
27
-
-
78650372218
-
-
P. Tosatti, J. Horn, A. J. Campbell, D. House, A. Nelson, S. P. Marsden, Adv. Synth. Catal. 2010, 352, 3153
-
(2010)
Adv. Synth. Catal
, vol.352
, pp. 3153
-
-
Tosatti, P.1
Horn, J.2
Campbell, A.J.3
House, D.4
Nelson, A.5
Marsden, S.P.6
-
28
-
-
67650239544
-
-
J. S. Nakhla, D. M. Schultz, J. P. Wolfe, Tetrahedron. 2009, 65, 6549
-
(2009)
Tetrahedron
, vol.65
, pp. 6549
-
-
Nakhla, J.S.1
Schultz, D.M.2
Wolfe, J.P.3
-
29
-
-
56449098619
-
-
M. B. Bertrand, J. D. Neukom, J. P. Wolfe, J. Org. Chem. 2008, 73, 8851
-
(2008)
J. Org. Chem
, vol.73
, pp. 8851
-
-
Bertrand, M.B.1
Neukom, J.D.2
Wolfe, J.P.3
-
30
-
-
67650351948
-
-
M. L. Leathen, B. R. Rosen, J. P. Wolfe, J. Org. Chem. 2009, 74, 5107
-
(2009)
J. Org. Chem
, vol.74
, pp. 5107
-
-
Leathen, M.L.1
Rosen, B.R.2
Wolfe, J.P.3
-
33
-
-
76149087813
-
-
J. Han, B. Xu, G. B. Hammond, J. Am. Chem. Soc. 2010, 132, 916
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 916
-
-
Han, J.1
Xu, B.2
Hammond, G.B.3
-
34
-
-
19744375923
-
-
E. J. Alexanian, C. Lee, E. J. Sorensen, J J. Am. Chem. Soc. 2005, 127, 7690
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 7690
-
-
Alexanian, E.J.1
Lee, C.2
Sorensen, E.J.J.3
-
35
-
-
55949127978
-
-
J. Horn, S. P. Marsden, A. Nelson, D. House, G. G. Weingarten, Org. Lett. 2008, 10, 4117
-
(2008)
Org. Lett
, vol.10
, pp. 4117
-
-
Horn, J.1
Marsden, S.P.2
Nelson, A.3
House, D.4
Weingarten, G.G.5
-
36
-
-
70349339545
-
-
J. Horn, H. Y. Li, S. P. Marsden, A. Nelson, R. J. Shearer, A. J. Campbell, D. House, G. G. Weingarten, Tetrahedron. 2009, 65, 9002
-
(2009)
Tetrahedron
, vol.65
, pp. 9002
-
-
Horn, J.1
Li, H.Y.2
Marsden, S.P.3
Nelson, A.4
Shearer, R.J.5
Campbell, A.J.6
House, D.7
Weingarten, G.G.8
-
37
-
-
1642298324
-
-
A. Klapars, S. Parris, K. W. Anderson, S. L. Buchwald, J. Am. Chem. Soc 2004, 126, 3529
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 3529
-
-
Klapars, A.1
Parris, S.2
Anderson, K.W.3
Buchwald, S.L.4
-
38
-
-
84868225054
-
-
C. Hirschh, J. S. Parker, M. W. D. Perry, M. F. Haddow, T. Gallagher, Org. Lett. 2012, 14, 4846
-
(2012)
Org. Lett
, vol.14
, pp. 4846
-
-
Hirschh, C.1
Parker, J.S.2
Perry, M.W.D.3
Haddow, M.F.4
Gallagher, T.5
-
39
-
-
84868258922
-
-
R. A. Brawn, C. R. W. Guimarães, K. F. McClure, S. Liras, Org. Lett. 2012, 14, 4802
-
(2012)
Org. Lett
, vol.14
, pp. 4802
-
-
Brawn, R.A.1
Guimarães, C.R.W.2
Mc Clure, K.F.3
Liras, S.4
-
41
-
-
35048843671
-
-
T. Yang, L. Campbell, D. J. Dixon, J. Am. Chem. Soc 2007, 129, 12070
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 12070
-
-
Yang, T.1
Campbell, L.2
Dixon, D.J.3
-
42
-
-
84862544617
-
-
A. Y. Sukhorukov, Y. D. Boyko, Y. V. Nelyubina, S. Gerard, S. L. Ioffe, V. A. Tartakovsky, J. Org. Chem. 2012, 77, 5465
-
(2012)
J. Org. Chem
, vol.77
, pp. 5465
-
-
Sukhorukov, A.Y.1
Boyko, Y.D.2
Nelyubina, Y.V.3
Gerard, S.4
Ioffe, S.L.5
Tartakovsky, V.A.6
-
43
-
-
84867718158
-
-
J. Zhou, L. Zhou, Y.-Y. Yeung, Org. Lett. 2012, 14, 5250
-
(2012)
Org. Lett
, vol.14
, pp. 5250
-
-
Zhou, J.1
Zhou, L.2
Yeung, Y.-Y.3
-
44
-
-
84864053600
-
-
J. C. Anderson, L. R. Horsfall, A. S. Kalogirou, M. R. Mills, G. J. Stepney, G. J. Tizzard, J. Org. Chem. 2012, 77, 6186
-
(2012)
J. Org. Chem
, vol.77
, pp. 6186
-
-
Anderson, J.C.1
Horsfall, L.R.2
Kalogirou, A.S.3
Mills, M.R.4
Stepney, G.J.5
Tizzard, G.J.6
-
45
-
-
70349895254
-
-
S. M.-C. Pelletier, P. C. Ray, D. J. Dixon, Org. Lett. 2009, 11, 4512
-
(2009)
Org. Lett
, vol.11
, pp. 4512
-
-
Pelletier, S.M.1
Ray, P.C.2
Dixon, D.J.3
-
46
-
-
79959907066
-
-
E. Ruijter, R. Scheffelaar, R. V. A. Orru, Angew. Chem., Int. Ed. 2011, 50, 6234
-
(2011)
Angew. Chem., Int. Ed
, vol.50
, pp. 6234
-
-
Ruijter, E.1
Scheffelaar, R.2
Orru, R.V.A.3
-
48
-
-
33747330904
-
-
I. W. Ku, S. Cho, M. R. Doddareddy, M. S. Jang, G. Keum, J.-H. Lee, B. Y. Chung, Y. Kim, H. Rhim, S. B. Kang, Bioorg. Med. Chem. Lett. 2006, 16, 5244
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 5244
-
-
Ku, I.W.1
Cho, S.2
Doddareddy, M.R.3
Jang, M.S.4
Keum, G.5
Lee, J.-H.6
Chung, B.Y.7
Kim, Y.8
Rhim, H.9
Kang, S.B.10
-
49
-
-
0001220302
-
-
Y. B. Kim, E. H. Choi, G. Keum, S. B. Kang, D. H. Lee, H. Y. Koh, Y. Kim, Org. Lett. 2001, 3, 4149
-
(2001)
Org. Lett
, vol.3
, pp. 4149
-
-
Kim, Y.B.1
Choi, E.H.2
Keum, G.3
Kang, S.B.4
Lee, D.H.5
Koh, H.Y.6
Kim, Y.7
-
50
-
-
0032485439
-
-
C. Hulme, M. M. Morrissette, F. A. Volz, C. J. Burns, Tetrahedron Lett. 1998, 39, 1113
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 1113
-
-
Hulme, C.1
Morrissette, M.M.2
Volz, F.A.3
Burns, C.J.4
-
52
-
-
81355139618
-
-
D. Robbins, A. F. Newton, C. Gignoux, J.-C. Legeay, A. Sinclair, M. Rejzek, C. A. Laxon, S. K. Yalamanchili, W. Lewis, M. A. O'Connell, R. A. Stockman, Chem. Sci. 2011, 2, 2232
-
(2011)
Chem. Sci
, vol.2
, pp. 2232
-
-
Robbins, D.1
Newton, A.F.2
Gignoux, C.3
Legeay, J.-C.4
Sinclair, A.5
Rejzek, M.6
Laxon, C.A.7
Yalamanchili, S.K.8
Lewis, W.9
O'connell, M.A.10
Stockman, R.A.11
-
53
-
-
84862025123
-
-
K. M. G. O'Connell, M. Díaz-Gavilán, W. R. J. D. Galloway, D. R. Spring, Beilstein J. Org. Chem. 2012, 8, 850
-
(2012)
Beilstein J. Org. Chem
, vol.8
, pp. 850
-
-
O'connell, K.M.G.1
Díaz-Gavilán, M.2
Galloway, W.R.J.D.3
Spring, D.R.4
-
54
-
-
58149346448
-
-
D. Morton, S. Leach, C. Cordier, S. Warriner, A. Nelson, Angew. Chem., Int. Ed. 2009, 48, 104
-
(2009)
Angew. Chem., Int. Ed
, vol.48
, pp. 104
-
-
Morton, D.1
Leach, S.2
Cordier, C.3
Warriner, S.4
Nelson, A.5
-
55
-
-
78649527328
-
-
L. A. Marcaurelle, E. Comer, S. Dandapani, J. R. Duvall, B. Gerard, S. Kesavan, M. D. Lee, H. Liu, J. T. Lowe, J.-C. Marie, C. A. Mulrooney, B. A. Pandya, A. Rowley, T. D. Ryba, B.-C. Suh, J. Wei, D. W. Young, L. B. Akella, N. T. Ross, Y.-L. Zhang, D. M. Fass, S. A. Reis, W.-N. Zhao, S. J. Haggarty, M. Palmer, M. A. Foley, J. Am. Chem. Soc. 2010, 132, 16962
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 16962
-
-
Marcaurelle, L.A.1
Comer, E.2
Dandapani, S.3
Duvall, J.R.4
Gerard, B.5
Kesavan, S.6
Lee, M.D.7
Liu, H.8
Lowe, J.T.9
Marie, J.-C.10
Mulrooney, C.A.11
Pandya, B.A.12
Rowley, A.13
Ryba, T.D.14
Suh, B.-C.15
Wei, J.16
Young, D.W.17
Akella, L.B.18
Ross, N.T.19
Zhang, Y.-L.20
Fass, D.M.21
Reis, S.A.22
Zhao, W.-N.23
Haggarty, S.J.24
Palmer, M.25
Foley, M.A.26
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