Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65

Journal of Biomedical Science

Volumn 20, Issue 1, 2013, Pages

  Bravo Cuellar, Alejandro ^a,b   Hernández Flores, Georgina ^a   Lerma Díaz, José Manuel ^a,b   Domínguez Rodríguez, Jorge Ramiro ^a,b   Jave Suárez, Luis F ^a   De Célis Carrillo, Ruth ^a   Aguilar Lemarroy, Adriana ^a   Gómez Lomeli, Paulina ^a,b   Ortiz Lazareno, Pablo Cesar ^a  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b UNIVERSITY OF GUADALAJARA   (Mexico)

Author keywords

Apoptosis related genes; Bcl 2; Bcl XL; Caspases; MG132; p65 phosphorylation; pentoxifylline; U937

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PENTOXIFYLLINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SURVIVIN; SYNAPTOTAGMIN I; BCL2L1 PROTEIN, HUMAN; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CARRIER PROTEIN; HSAJ2425 PROTEIN, HUMAN; LEUPEPTIN; PROTEIN BCL X; TUMOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME RELEASE; G1 PHASE CELL CYCLE CHECKPOINT; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; BIOSYNTHESIS; CELL STRAIN U937; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; BCL-X PROTEIN; CARRIER PROTEINS; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA; LEUPEPTINS; NEOPLASM PROTEINS; NF-KAPPA B; PENTOXIFYLLINE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; U937 CELLS;

EID: 84874389242     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-20-13     Document Type: Article

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