-
2
-
-
33947426526
-
The CASBAH: A searchable database of caspase substrates
-
A. U. Luthi, S. J. Martin, The CASBAH: A searchable database of caspase substrates. Cell Death Differ. 14, 641-650 (2007).
-
(2007)
Cell Death Differ.
, vol.14
, pp. 641-650
-
-
Luthi, A.U.1
Martin, S.J.2
-
3
-
-
49549113643
-
Global mapping of the topography and magnitude of proteolytic events in apoptosis
-
M. M. Dix, G. M. Simon, B. F. Cravatt, Global mapping of the topography and magnitude of proteolytic events in apoptosis. Cell 134, 679-691 (2008).
-
(2008)
Cell
, vol.134
, pp. 679-691
-
-
Dix, M.M.1
Simon, G.M.2
Cravatt, B.F.3
-
5
-
-
39449093070
-
Caspase activation cascades in apoptosis
-
S. E. Logue, S. J. Martin, Caspase activation cascades in apoptosis. Biochem. Soc. Trans. 36, 1-9 (2008).
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 1-9
-
-
Logue, S.E.1
Martin, S.J.2
-
6
-
-
0033601746
-
Ordering the cytochrome cinitiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase- 9-dependent manner
-
E. A. Slee, M. T. Harte, R. M. Kluck, B. B.Wolf, C. A. Casiano, D. D. Newmeyer, H. G. Wang, J. C. Reed, D. W. Nicholson, E. S. Alnemri, D. R. Green, S. J. Martin, Ordering the cytochrome cinitiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase- 9-dependent manner. J. Cell Biol. 144, 281-292 (1999).
-
(1999)
J. Cell Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
Green, D.R.11
Martin, S.J.12
-
7
-
-
0035369143
-
The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
-
DOI 10.1016/S0968-0004(01)01844-8, PII S0968000401018448
-
C. Adrain, S. J. Martin, The mitochondrial apoptosome: A killer unleashed by the cytochrome seas. Trends Biochem. Sci. 26, 390-397 (2001). (Pubitemid 32530658)
-
(2001)
Trends in Biochemical Sciences
, vol.26
, Issue.6
, pp. 390-397
-
-
Adrain, C.1
Martin, S.J.2
-
8
-
-
0344908231
-
Portrait of a killer: The mitochondrial apoptosome emerges from the shadows
-
M. M. Hill, C. Adrain, S. J. Martin, Portrait of a killer: The mitochondrial apoptosome emerges from the shadows. Mol. Interv. 3, 19-26 (2003).
-
(2003)
Mol. Interv.
, vol.3
, pp. 19-26
-
-
Hill, M.M.1
Adrain, C.2
Martin, S.J.3
-
9
-
-
67650455882
-
The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer
-
S. Malladi, M. Challa-Malladi, H. O. Fearnhead, S. B. Bratton, The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer. EMBO J. 28, 1916-1925 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 1916-1925
-
-
Malladi, S.1
Challa-Malladi, M.2
Fearnhead, H.O.3
Bratton, S.B.4
-
10
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
-
J. E. Chipuk, D. R. Green, How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol. 18, 157-164 (2008).
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 157-164
-
-
Chipuk, J.E.1
Green, D.R.2
-
11
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
P. Li, D. Nijhawan, I. Budihardjo, S. M. Srinivasula, M. Ahmad, E. S. Alnemri, X.Wang, Cytochrome c and dATP-dependent formation of Apaf-1/caspase- 9 complex initiates an apoptotic protease cascade. Cell 91, 479-489 (1997). (Pubitemid 27508237)
-
(1997)
Cell
, vol.91
, Issue.4
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
12
-
-
27644505459
-
Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1
-
DOI 10.1073/pnas.0507900102
-
H. E. Kim, F. Du, M. Fang, X.Wang, Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc. Natl. Acad. Sci. U.S.A. 102, 17545-17550 (2005). (Pubitemid 41803534)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.49
, pp. 17545-17550
-
-
Kim, H.-E.1
Du, F.2
Fang, M.3
Wang, X.4
-
13
-
-
33646024628
-
The apoptosome activates caspase-9 by dimerization
-
C. Pop, J. Timmer, S. Sperandio, G. S. Salvesen, The apoptosome activates caspase-9 by dimerization. Mol. Cell 22, 269-275 (2006).
-
(2006)
Mol. Cell
, vol.22
, pp. 269-275
-
-
Pop, C.1
Timmer, J.2
Sperandio, S.3
Salvesen, G.S.4
-
14
-
-
33845501864
-
Apoptosome: A platform for the activation of initiator caspases
-
DOI 10.1038/sj.cdd.4402028, PII 4402028
-
Q. Bao, Y. Shi, Apoptosome: A platform for the activation of initiator caspases. Cell Death Differ. 14, 56-65 (2007). (Pubitemid 44911894)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.1
, pp. 56-65
-
-
Bao, Q.1
Shi, Y.2
-
15
-
-
34447565905
-
Caspase-9 cleavage, do you need it?
-
D. Twiddy, K. Cain, Caspase-9 cleavage, do you need it? Biochem. J. 405, e1-e2 (2007).
-
(2007)
Biochem. J.
, vol.405
-
-
Twiddy, D.1
Cain, K.2
-
16
-
-
0033573020
-
Caspase-9 and APAF-1 form an active holoenzyme
-
DOI 10.1101/gad.13.24.3179
-
J. Rodriguez, Y. Lazebnik, Caspase-9 and APAF- 1 form an active holoenzyme. Genes Dev. 13, 3179-3184 (1999). (Pubitemid 30030439)
-
(1999)
Genes and Development
, vol.13
, Issue.24
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
17
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
DOI 10.1016/S1097-2765(03)00054-6
-
E. N. Shiozaki, J. Chai, D. J. Rigotti, S. J. Riedl, P. Li, S. M. Srinivasula, E. S. Alnemri, R. Fairman, Y. Shi, Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell 11, 519-527 (2003). (Pubitemid 36293842)
-
(2003)
Molecular Cell
, vol.11
, Issue.2
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
Alnemri, E.S.7
Fairman, R.8
Shi, Y.9
-
18
-
-
34347209876
-
Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9
-
DOI 10.1042/BJ20070288
-
J. B. Denault, B. P. Eckelman, H. Shin, C. Pop, G. S. Salvesen, Caspase 3 attenuates XIAP (Xlinked inhibitor of apoptosis protein)-mediated inhibition of caspase 9. Biochem. J. 405, 11-19 (2007). (Pubitemid 46999920)
-
(2007)
Biochemical Journal
, vol.405
, Issue.1
, pp. 11-19
-
-
Denault, J.-B.1
Eckelman, B.P.2
Shin, H.3
Pop, C.4
Salvesen, G.S.5
-
19
-
-
0034105784
-
Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
-
K. Cain, S. B. Bratton, C. Langlais, G. Walker, D. G. Brown, X. M. Sun, G. M. Cohen, Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes. J. Biol. Chem. 275, 6067-6070 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6067-6070
-
-
Cain, K.1
Bratton, S.B.2
Langlais, C.3
Walker, G.4
Brown, D.G.5
Sun, X.M.6
Cohen, G.M.7
-
20
-
-
25444528729
-
The GAPs, GEFs, and GDIs of heterotrimeric G-protein á subunits
-
D. P. Siderovski, F. S. Willard, The GAPs, GEFs, and GDIs of heterotrimeric G-protein á subunits. Int. J. Biol. Sci. 1, 51-66 (2005).
-
(2005)
Int. J. Biol. Sci.
, vol.1
, pp. 51-66
-
-
Siderovski, D.P.1
Willard, F.S.2
-
21
-
-
7244223248
-
Cell differentiation: Reciprocal regulation of Apaf-1 and the inhibitor of apoptosis proteins
-
D. Lindholm, U. Arumae, Cell differentiation: Reciprocal regulation of Apaf-1 and the inhibitor of apoptosis proteins. J. Cell Biol. 167, 193-195 (2004).
-
(2004)
J. Cell Biol.
, vol.167
, pp. 193-195
-
-
Lindholm, D.1
Arumae, U.2
-
22
-
-
33646087420
-
The apoptosome: Physiological, developmental, and pathological modes of regulation
-
Z. T. Schafer, S. Kornbluth, The apoptosome: Physiological, developmental, and pathological modes of regulation. Dev. Cell 10, 549-561 (2006).
-
(2006)
Dev. Cell
, vol.10
, pp. 549-561
-
-
Schafer, Z.T.1
Kornbluth, S.2
-
23
-
-
27944469109
-
Regulation of caspase 9 through phosphorylation by protein kinase C ζ in response to hyperosmotic stress
-
S. C. Brady, L. A. Allan, P. R. Clarke, Regulation of caspase 9 through phosphorylation by protein kinase C ζ in response to hyperosmotic stress. Mol. Cell. Biol. 25, 10543-10555 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10543-10555
-
-
Brady, S.C.1
Allan, L.A.2
Clarke, P.R.3
-
24
-
-
0038726089
-
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
-
L. A. Allan, N. Morrice, S. Brady, G. Magee, S. Pathak, P. R. Clarke, Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nat. Cell Biol. 5, 647-654 (2003).
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 647-654
-
-
Allan, L.A.1
Morrice, N.2
Brady, S.3
Magee, G.4
Pathak, S.5
Clarke, P.R.6
-
25
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
D. Acehan, X. Jiang, D. G. Morgan, J. E. Heuser, X.Wang, C.W. Akey, Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation. Mol. Cell 9, 423-432 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
26
-
-
27644483812
-
A structure of the human apoptosome at 12.8 Å resolution provides insights into this cell death platform
-
X.Yu, D. Acehan, J. F. Menetret, C. R. Booth, S. J. Ludtke, S. J. Riedl, Y. Shi, X.Wang, C.W. Akey, A structure of the human apoptosome at 12.8 Å resolution provides insights into this cell death platform. Structure 13, 1725-1735 (2005).
-
(2005)
Structure
, vol.13
, pp. 1725-1735
-
-
Yu, X.1
Acehan, D.2
Menetret, J.F.3
Booth, C.R.4
Ludtke, S.J.5
Riedl, S.J.6
Shi, Y.7
Wang, X.8
Akey, C.W.9
-
27
-
-
0033596980
-
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
H. Zou, Y. Li, X. Liu, X. Wang, An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274, 11549-11556 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
28
-
-
77953659279
-
-
Work in the Martin laboratory is supported by grants from Science Foundation Ireland (SRCG20336 and 08/IN.1/B2031) and the Wellcome Trust UK (082749). C.A. is supported by a longterm fellowship from The International Human Frontier Science Program Organization
-
Work in the Martin laboratory is supported by grants from Science Foundation Ireland (SRCG20336 and 08/IN.1/B2031) and the Wellcome Trust UK (082749). C.A. is supported by a longterm fellowship from The International Human Frontier Science Program Organization.
-
-
-
|