In vivo and in vitro sensitization of leukemic cells to adriamycin-induced apoptosis by pentoxifylline: Involvement of caspase cascades and IκBα phosphorylation

Immunology Letters

Volumn 103, Issue 2, 2006, Pages 149-158

  Lerma Díaz, José Manuel ^a   Hernández Flores, Georgina ^a   Domínguez Rodríguez, Jorge R ^a   Ortíz Lazareno, Pablo C ^a   Gómez Contreras, Piedad ^a   Cervantes Munguía, Ramón ^a,b   Scott Algara, Daniel ^c   Aguilar Lemarroy, Adriana ^a   Jave Suárez, Luis F ^a   Bravo Cuellar, Alejandro ^a,b  

^a CENTRO DE INVESTIGACIÓN BIOMÉDICA DE OCCIDENTE   (Mexico)

^b UNIVERSITY OF GUADALAJARA   (Mexico)

^c INSTITUT PASTEUR   (France)

Author keywords

Adriamycin; Apoptosis; Caspase cascades; I B phosphorylation; Leukemic cells; Pentoxifylline

Indexed keywords

ACRIDINE ORANGE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 10; CASPASE 3; CASPASE 7; CASPASE 9; DNA FRAGMENT; DOXORUBICIN; ETHIDIUM BROMIDE; I KAPPA B ALPHA; PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DETERMINATION; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; LYMPHOMA CELL; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENSITIZATION; STAINING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; DOXORUBICIN; HUMANS; I-KAPPA B PROTEINS; LEUKEMIA; MALE; MICE; MICE, INBRED BALB C; PENTOXIFYLLINE; PHOSPHORYLATION; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 31544468090     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2005.10.019     Document Type: Article

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