Swainsonine promotes apoptosis in human oesophageal squamous cell carcinoma cells in vitro and in vivo through activation of mitochondrial pathway

Journal of Biosciences

Volumn 37, Issue 1, 2012, Pages 1005-1016

  Li, Zhaocai ^a   Huang, Yong ^a   Dong, Feng ^a   Li, Wei ^a   Ding, Li ^a   Yu, Gaoshui ^a   Xu, Dan ^a   Yang, Yuanyuan ^a   Xu, Xingang ^a   Tong, Dewen ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; Eca 109 cells; Mitochondrial pathway; Swainsonine

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; SWAINSONINE; CASPASE; PRIMER DNA;

ALKALOID; APOPTOSIS; CYTOCHROME; DIGESTIVE SYSTEM; ENZYME; MITOCHONDRION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER SIZE; CELL ASSAY; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DETERMINATION; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; ENZYME ACTIVATION; ENZYME RELEASE; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TREATMENT DURATION; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; ENZYMOLOGY; ESOPHAGUS TUMOR; METABOLISM; MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; XENOGRAFT;

MUS;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CASPASES; CELL LINE, TUMOR; DNA PRIMERS; ENZYME ACTIVATION; ESOPHAGEAL NEOPLASMS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, NUDE; MITOCHONDRIA; REAL-TIME POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWAINSONINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84876453945     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-012-9265-8     Document Type: Article

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