-
1
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
PMID:19956173
-
Zenz T, Mertens D, Küppers R, Döhner H, Stilgenbauer S. From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer 2010; 10:37-50; PMID:19956173.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 37-50
-
-
Zenz, T.1
Mertens, D.2
Küppers, R.3
Döhner, H.4
Stilgenbauer, S.5
-
2
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
PMID:10729832
-
Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16:168-74; PMID:10729832; http://dx.doi. org/10.1016/S0168-9525(99)01971-X.
-
(2000)
Trends Genet
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
3
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
PMID:11782440
-
Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16:6-21; PMID:11782440; http://dx.doi.org/10.1101/gad.947102.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
4
-
-
67349190247
-
Linking DNA methylation and histone modification: Patterns and paradigms
-
PMID:19308066
-
Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 2009; 10:295-304; PMID:19308066; http:// dx.doi.org/10.1038/nrg2540.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
5
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
PMID:11891299
-
Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002; 99:3740-5; PMID:11891299; http://dx.doi.org/10.1073/pnas.052410099.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
6
-
-
34547792388
-
Epigenetic gene silencing in cancer: The DNA hypermethylome
-
Spec No 1 PMID:17613547
-
Esteller M. Epigenetic gene silencing in cancer: the DNA hypermethylome. Hum Mol Genet 2007; 16(Spec No 1):R50-9; PMID:17613547; http://dx.doi. org/10.1093/hmg/ddm018.
-
(2007)
Hum Mol Genet
, vol.16
-
-
Esteller, M.1
-
7
-
-
34248217444
-
Methylation of human microRNA genes in normal and neoplastic cells
-
PMID:17457051
-
Weber B, Stresemann C, Brueckner B, Lyko F. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 2007; 6:1001-5; PMID:17457051; http://dx.doi.org/10.4161/ cc.6.9.4209.
-
(2007)
Cell Cycle
, vol.6
, pp. 1001-1005
-
-
Weber, B.1
Stresemann, C.2
Brueckner, B.3
Lyko, F.4
-
8
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
PMID:12042769
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3:415-28; PMID:12042769.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
9
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
PMID:12702868
-
Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003; 300:455; PMID:12702868; http://dx.doi.org/10.1126/science. 1083557.
-
(2003)
Science
, vol.300
, pp. 455
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
10
-
-
33749037187
-
Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers
-
PMID:16951157
-
Rodriguez J, Frigola J, Vendrell E, Risques RA, Fraga MF, Morales C, et al. Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers. Cancer Res 2006; 66:8462-9468; PMID:16951157; http://dx.doi. org/10.1158/0008-5472.CAN-06-0293.
-
(2006)
Cancer Res
, vol.66
, pp. 8462-9468
-
-
Rodriguez, J.1
Frigola, J.2
Vendrell, E.3
Risques, R.A.4
Fraga, M.F.5
Morales, C.6
-
11
-
-
0024272160
-
Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia
-
PMID:2904292
-
Lipsanen V, Leinonen P, Alhonen L, Jänne J. Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia. Blood 1988; 72:2042-4; PMID:2904292.
-
(1988)
Blood
, vol.72
, pp. 2042-2044
-
-
Lipsanen, V.1
Leinonen, P.2
Alhonen, L.3
Jänne, J.4
-
12
-
-
0026786945
-
Genomic hypomethylation in human chronic lymphocytic leukemia
-
PMID:1382719
-
Wahlfors J, Hiltunen H, Heinonen K, Hämäläinen E, Alhonen L, Jänne J. Genomic hypomethylation in human chronic lymphocytic leukemia. Blood 1992; 80:2074-80; PMID:1382719.
-
(1992)
Blood
, vol.80
, pp. 2074-2080
-
-
Wahlfors, J.1
Hiltunen, H.2
Heinonen, K.3
Hämäläinen, E.4
Alhonen, L.5
Jänne, J.6
-
13
-
-
79951499200
-
Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia
-
PMID:20930513
-
Fabris S, Bollati V, Agnelli L, Morabito F, Motta V, Cutrona G, et al. Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia. Epigenetics 2011; 6:188-94; PMID:20930513; http:// dx.doi.org/10.4161/epi.6.2.13528.
-
(2011)
Epigenetics
, vol.6
, pp. 188-194
-
-
Fabris, S.1
Bollati, V.2
Agnelli, L.3
Morabito, F.4
Motta, V.5
Cutrona, G.6
-
14
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
PMID:23064414
-
Kulis M, Heath S, Bibikova M, Queirós AC, Navarro A, Clot G, et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet 2012; 44:1236-42; PMID:23064414; http://dx.doi.org/10.1038/ng.2443.
-
(2012)
Nat Genet
, vol.44
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
Queirós, A.C.4
Navarro, A.5
Clot, G.6
-
15
-
-
0027239823
-
bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
-
PMID:8104532
-
Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 1993; 82:1820-8; PMID:8104532.
-
(1993)
Blood
, vol.82
, pp. 1820-1828
-
-
Hanada, M.1
Delia, D.2
Aiello, A.3
Stadtmauer, E.4
Reed, J.C.5
-
16
-
-
0030722392
-
Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance
-
PMID:9815593
-
Kantharidis P, El-Osta A, deSilva M, Wall DM, Hu XF, Slater A, et al. Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance. Clin Cancer Res 1997; 3:2025-32; PMID:9815593.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2025-2032
-
-
Kantharidis, P.1
El-Osta, A.2
deSilva, M.3
Wall, D.M.4
Hu, X.F.5
Slater, A.6
-
17
-
-
0035100284
-
TCL1 is activated by chromosomal rearrangement or by hypomethylation
-
PMID:11241786
-
Yuille MR, Condie A, Stone EM, Wilsher J, Bradshaw PS, Brooks L, et al. TCL1 is activated by chromosomal rearrangement or by hypomethylation. Genes Chromosomes Cancer 2001; 30:336-41; PMID:11241786; http://dx.doi.org/10.1002/ gcc.1099.
-
(2001)
Genes Chromosomes Cancer
, vol.30
, pp. 336-341
-
-
Yuille, M.R.1
Condie, A.2
Stone, E.M.3
Wilsher, J.4
Bradshaw, P.S.5
Brooks, L.6
-
18
-
-
0034657952
-
Hypermethylation of E-cadherin in leukemia
-
PMID:10807790
-
Melki JR, Vincent PC, Brown RD, Clark SJ. Hypermethylation of E-cadherin in leukemia. Blood 2000; 95:3208-13; PMID:10807790.
-
(2000)
Blood
, vol.95
, pp. 3208-3213
-
-
Melki, J.R.1
Vincent, P.C.2
Brown, R.D.3
Clark, S.J.4
-
19
-
-
0029558476
-
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers
-
PMID:8557030
-
Berx G, Cleton-Jansen AM, Nollet F, de Leeuw WJ, van de Vijver M, Cornelisse C, et al. E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J 1995; 14:6107-15; PMID:8557030.
-
(1995)
EMBO J
, vol.14
, pp. 6107-6115
-
-
Berx, G.1
Cleton-Jansen, A.M.2
Nollet, F.3
de Leeuw, W.J.4
van de Vijver, M.5
Cornelisse, C.6
-
20
-
-
67650912362
-
CpG island methylation patterns in chronic lymphocytic leukemia
-
PMID:19347729
-
Seeliger B, Wilop S, Osieka R, Galm O, Jost E. CpG island methylation patterns in chronic lymphocytic leukemia. Leuk Lymphoma 2009; 50:419-26; PMID:19347729; http://dx.doi. org/10.1080/10428190902756594.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 419-426
-
-
Seeliger, B.1
Wilop, S.2
Osieka, R.3
Galm, O.4
Jost, E.5
-
21
-
-
0036142690
-
CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia
-
PMID:11823034
-
Bechter OE, Eisterer W, Dlaska M, Kühr T, Thaler J. CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia. Exp Hematol 2002; 30:26-33; PMID:11823034; http://dx.doi.org/10.1016/S0301-472X(01)00760-3.
-
(2002)
Exp Hematol
, vol.30
, pp. 26-33
-
-
Bechter, O.E.1
Eisterer, W.2
Dlaska, M.3
Kühr, T.4
Thaler, J.5
-
22
-
-
21244503530
-
TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia
-
PMID:15809452
-
Raval A, Lucas DM, Matkovic JJ, Bennett KL, Liyanarachchi S, Young DC, et al. TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia. J Clin Oncol 2005; 23:3877-85; PMID:15809452; http://dx.doi.org/10.1200/ JCO.2005.02.196.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3877-3885
-
-
Raval, A.1
Lucas, D.M.2
Matkovic, J.J.3
Bennett, K.L.4
Liyanarachchi, S.5
Young, D.C.6
-
23
-
-
24944464149
-
ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia
-
PMID:16079107
-
Corcoran M, Parker A, Orchard J, Davis Z, Wirtz M, Schmitz OJ, et al. ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia. Haematologica 2005; 90:1078-88; PMID:16079107.
-
(2005)
Haematologica
, vol.90
, pp. 1078-1088
-
-
Corcoran, M.1
Parker, A.2
Orchard, J.3
Davis, Z.4
Wirtz, M.5
Schmitz, O.J.6
-
24
-
-
77952094636
-
ZAP-70 intron1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia
-
PMID:19944462
-
Chantepie SP, Vaur D, Grunau C, Salaün V, Briand M, Parienti JJ, et al. ZAP-70 intron1 DNA methylation status: determination by pyrosequencing in B chronic lymphocytic leukemia. Leuk Res 2010; 34:800-8; PMID:19944462; http://dx.doi.org/10.1016/j.leukres. 2009.10.018.
-
(2010)
Leuk Res
, vol.34
, pp. 800-808
-
-
Chantepie, S.P.1
Vaur, D.2
Grunau, C.3
Salaün, V.4
Briand, M.5
Parienti, J.J.6
-
25
-
-
84864071185
-
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia
-
PMID:22564988
-
Claus R, Lucas DM, Stilgenbauer S, Ruppert AS, Yu LB, Zucknick M, et al. Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia. J Clin Oncol 2012; 30:2483-91; PMID:22564988; http://dx.doi. org/10.1200/JCO.2011.39.3090.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2483-2491
-
-
Claus, R.1
Lucas, D.M.2
Stilgenbauer, S.3
Ruppert, A.S.4
Yu, L.B.5
Zucknick, M.6
-
26
-
-
33745198269
-
Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL
-
PMID:16688227
-
Strathdee G, Sim A, Parker A, Oscier D, Brown R. Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL. Leukemia 2006; 20:1326-9; PMID:16688227; http://dx.doi.org/10.1038/sj.leu.2404254.
-
(2006)
Leukemia
, vol.20
, pp. 1326-1329
-
-
Strathdee, G.1
Sim, A.2
Parker, A.3
Oscier, D.4
Brown, R.5
-
27
-
-
0034929247
-
Homeobox genes in normal and malignant cells
-
PMID:11424082
-
Cillo C, Cantile M, Faiella A, Boncinelli E. Homeobox genes in normal and malignant cells. J Cell Physiol 2001; 188:161-9; PMID:11424082; http://dx.doi. org/10.1002/jcp.1115.
-
(2001)
J Cell Physiol
, vol.188
, pp. 161-169
-
-
Cillo, C.1
Cantile, M.2
Faiella, A.3
Boncinelli, E.4
-
28
-
-
34548819044
-
Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis
-
PMID:17785556
-
Strathdee G, Holyoake TL, Sim A, Parker A, Oscier DG, Melo JV, et al. Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis. Clin Cancer Res 2007; 13:5048-55; PMID:17785556; http://dx.doi.org/10.1158/1078-0432.CCR-07-0919.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5048-5055
-
-
Strathdee, G.1
Holyoake, T.L.2
Sim, A.3
Parker, A.4
Oscier, D.G.5
Melo, J.V.6
-
29
-
-
79952389811
-
Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia
-
PMID:21051931
-
Irving L, Mainou-Fowler T, Parker A, Ibbotson RE, Oscier DG, Strathdee G. Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia. Epigenetics 2011; 6:300-6; PMID:21051931; http://dx.doi.org/10.4161/ epi.6.3.14038.
-
(2011)
Epigenetics
, vol.6
, pp. 300-306
-
-
Irving, L.1
Mainou-Fowler, T.2
Parker, A.3
Ibbotson, R.E.4
Oscier, D.G.5
Strathdee, G.6
-
30
-
-
0037330832
-
Microsatellite instability and hMLH1 promoter hypermethylation in Richter's transformation of chronic lymphocytic leukemia
-
PMID:12592341
-
Fülöp Z, Csernus B, Tímár B, Szepesi A, Matolcsy A. Microsatellite instability and hMLH1 promoter hypermethylation in Richter's transformation of chronic lymphocytic leukemia. Leukemia 2003; 17:411-5; PMID:12592341; http://dx.doi.org/10.1038/ sj.leu.2402792.
-
(2003)
Leukemia
, vol.17
, pp. 411-415
-
-
Fülöp, Z.1
Csernus, B.2
Tímár, B.3
Szepesi, A.4
Matolcsy, A.5
-
31
-
-
34249314024
-
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia
-
PMID:17540169
-
Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS, et al. Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell 2007; 129:879-90; PMID:17540169; http://dx.doi.org/10.1016/j.cell.2007.03.043.
-
(2007)
Cell
, vol.129
, pp. 879-890
-
-
Raval, A.1
Tanner, S.M.2
Byrd, J.C.3
Angerman, E.B.4
Perko, J.D.5
Chen, S.S.6
-
32
-
-
84859015067
-
Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia
-
PMID:22470559
-
Hanoun M, Eisele L, Suzuki M, Greally JM, Hüttmann A, Aydin S, et al. Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia. PLoS One 2012; 7:e34347; PMID:22470559; http://dx.doi. org/10.1371/journal.pone.0034347.
-
(2012)
PLoS One
, vol.7
-
-
Hanoun, M.1
Eisele, L.2
Suzuki, M.3
Greally, J.M.4
Hüttmann, A.5
Aydin, S.6
-
33
-
-
69949088319
-
Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia
-
PMID:19550140
-
Dunwell TL, Dickinson RE, Stankovic T, Dallol A, Weston V, Austen B, et al. Frequent epigenetic inactivation of the SLIT2 gene in chronic and acute lymphocytic leukemia. Epigenetics 2009; 4:265-9; PMID:19550140.
-
(2009)
Epigenetics
, vol.4
, pp. 265-269
-
-
Dunwell, T.L.1
Dickinson, R.E.2
Stankovic, T.3
Dallol, A.4
Weston, V.5
Austen, B.6
-
34
-
-
31544469759
-
CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia
-
PMID:16423993
-
Liu TH, Raval A, Chen SS, Matkovic JJ, Byrd JC, Plass C. CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. Cancer Res 2006; 66:653-8; PMID:16423993; http://dx.doi.org/10.1158/0008-5472.CAN-05-3712.
-
(2006)
Cancer Res
, vol.66
, pp. 653-658
-
-
Liu, T.H.1
Raval, A.2
Chen, S.S.3
Matkovic, J.J.4
Byrd, J.C.5
Plass, C.6
-
35
-
-
56049111627
-
Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia
-
PMID:18765431
-
Chim CS, Pang R, Liang R. Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia. J Clin Pathol 2008; 61:1214-9; PMID:18765431; http://dx.doi.org/10.1136/ jcp.2008.060152.
-
(2008)
J Clin Pathol
, vol.61
, pp. 1214-1219
-
-
Chim, C.S.1
Pang, R.2
Liang, R.3
-
36
-
-
84861831963
-
Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia
-
PMID:22672427
-
Moskalev EA, Luckert K, Vorobjev IA, Mastitsky SE, Gladkikh AA, Stephan A, et al. Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia. BMC Cancer 2012; 12:213; PMID:22672427; http://dx.doi. org/10.1186/1471-2407-12-213.
-
(2012)
BMC Cancer
, vol.12
, pp. 213
-
-
Moskalev, E.A.1
Luckert, K.2
Vorobjev, I.A.3
Mastitsky, S.E.4
Gladkikh, A.A.5
Stephan, A.6
-
37
-
-
84858220295
-
KIBRA gene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia
-
PMID:22430796
-
Shinawi T, Hill V, Dagklis A, Baliakas P, Stamatopoulos K, Agathanggelou A, et al. KIBRA gene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia. Epigenetics 2012; 7:211-5; PMID:22430796; http:// dx.doi.org/10.4161/epi.7.3.19222.
-
(2012)
Epigenetics
, vol.7
, pp. 211-215
-
-
Shinawi, T.1
Hill, V.2
Dagklis, A.3
Baliakas, P.4
Stamatopoulos, K.5
Agathanggelou, A.6
-
38
-
-
3042854223
-
Quantitative analysis of DNA methylation in chronic lymphocytic leukemia patients
-
PMID:15188237
-
Lyko F, Stach D, Brenner A, Stilgenbauer S, Döhner H, Wirtz M, et al. Quantitative analysis of DNA methylation in chronic lymphocytic leukemia patients. Electrophoresis 2004; 25:1530-5; PMID:15188237; http://dx.doi.org/10.1002/elps.200305830.
-
(2004)
Electrophoresis
, vol.25
, pp. 1530-1535
-
-
Lyko, F.1
Stach, D.2
Brenner, A.3
Stilgenbauer, S.4
Döhner, H.5
Wirtz, M.6
-
39
-
-
34249827572
-
Progressive disease in chronic lymphocytic leukemia is correlated with the DNA methylation index
-
PMID:16970987
-
Yu MK, Bergonia H, Szabo A, Phillips JD. Progressive disease in chronic lymphocytic leukemia is correlated with the DNA methylation index. Leuk Res 2007; 31:773-7; PMID:16970987; http://dx.doi. org/10.1016/j.leukres.2006.07.007.
-
(2007)
Leuk Res
, vol.31
, pp. 773-777
-
-
Yu, M.K.1
Bergonia, H.2
Szabo, A.3
Phillips, J.D.4
-
40
-
-
11144356462
-
Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets
-
PMID:15059895
-
Rush LJ, Raval A, Funchain P, Johnson AJ, Smith L, Lucas DM, et al. Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets. Cancer Res 2004; 64:2424-33; PMID:15059895; http://dx.doi.org/10.1158/0008-5472.CAN-03-2870.
-
(2004)
Cancer Res
, vol.64
, pp. 2424-2433
-
-
Rush, L.J.1
Raval, A.2
Funchain, P.3
Johnson, A.J.4
Smith, L.5
Lucas, D.M.6
-
41
-
-
77954126563
-
Large-scale analysis of DNA methylation in chronic lymphocytic leukemia
-
PMID:20495622
-
Rahmatpanah FB, Carstens S, Hooshmand SI, Welsh EC, Sjahputera O, Taylor KH, et al. Large-scale analysis of DNA methylation in chronic lymphocytic leukemia. Epigenomics 2009; 1:39-61; PMID:20495622; http:// dx.doi.org/10.2217/epi.09.10.
-
(2009)
Epigenomics
, vol.1
, pp. 39-61
-
-
Rahmatpanah, F.B.1
Carstens, S.2
Hooshmand, S.I.3
Welsh, E.C.4
Sjahputera, O.5
Taylor, K.H.6
-
42
-
-
84873570131
-
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments
-
PMID:22922567
-
Cahill N, Bergh AC, Kanduri M, Goransson-Kultima H, Mansouri L, Isaksson A, et al. 450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments. Leukemia 2013; 27:150-8; PMID:22922567.
-
(2013)
Leukemia
, vol.27
, pp. 150-158
-
-
Cahill, N.1
Bergh, A.C.2
Kanduri, M.3
Goransson-Kultima, H.4
Mansouri, L.5
Isaksson, A.6
-
43
-
-
77957370748
-
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
-
PMID:20484983
-
Tong WG, Wierda WG, Lin E, Kuang SQ, Bekele BN, Estrov Z, et al. Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics 2010; 5:499-508; PMID:20484983; http://dx.doi.org/10.4161/ epi.5.6.12179.
-
(2010)
Epigenetics
, vol.5
, pp. 499-508
-
-
Tong, W.G.1
Wierda, W.G.2
Lin, E.3
Kuang, S.Q.4
Bekele, B.N.5
Estrov, Z.6
-
44
-
-
75649133610
-
Differential genome-wide arraybased methylation profiles in prognostic subsets of chronic lymphocytic leukemia
-
PMID:19897574
-
Kanduri M, Cahill N, Göransson H, Enström C, Ryan F, Isaksson A, et al. Differential genome-wide arraybased methylation profiles in prognostic subsets of chronic lymphocytic leukemia. Blood 2010; 115:296-305; PMID:19897574; http://dx.doi.org/10.1182/ blood-2009-07-232868.
-
(2010)
Blood
, vol.115
, pp. 296-305
-
-
Kanduri, M.1
Cahill, N.2
Göransson, H.3
Enström, C.4
Ryan, F.5
Isaksson, A.6
-
45
-
-
84870735334
-
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subsetbiased global DNA methylation profiles
-
PMID:23154584
-
Kanduri M, Marincevic M, Halldórsdóttir AM, Mansouri L, Junevik K, Ntoufa S, et al. Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subsetbiased global DNA methylation profiles. Epigenetics 2012; 7:1435-42; PMID:23154584; http://dx.doi. org/10.4161/epi.22901.
-
(2012)
Epigenetics
, vol.7
, pp. 1435-1442
-
-
Kanduri, M.1
Marincevic, M.2
Halldórsdóttir, A.M.3
Mansouri, L.4
Junevik, K.5
Ntoufa, S.6
-
46
-
-
59149084538
-
The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
-
PMID:19151715
-
Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, Onyango P, et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009; 41:178-86; PMID:19151715; http://dx.doi. org/10.1038/ng.298.
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
-
47
-
-
78649982904
-
High-resolution genomic screening in mantle cell lymphoma--specific changes correlate with genomic complexity, the proliferation signature and survival
-
PMID:21117067
-
Halldórsdóttir AM, Sander B, Göransson H, Isaksson A, Kimby E, Mansouri M, et al. High-resolution genomic screening in mantle cell lymphoma--specific changes correlate with genomic complexity, the proliferation signature and survival. Genes Chromosomes Cancer 2011; 50:113-21; PMID:21117067; http:// dx.doi.org/10.1002/gcc.20836.
-
(2011)
Genes Chromosomes Cancer
, vol.50
, pp. 113-121
-
-
Halldórsdóttir, A.M.1
Sander, B.2
Göransson, H.3
Isaksson, A.4
Kimby, E.5
Mansouri, M.6
-
48
-
-
84861922114
-
Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia
-
PMID:22534504
-
Pei LR, Choi JH, Liu JM, Lee EJ, McCarthy B, Wilson JM, et al. Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia. Epigenetics 2012; 7:567-78; PMID:22534504; http://dx.doi.org/10.4161/ epi.20237.
-
(2012)
Epigenetics
, vol.7
, pp. 567-578
-
-
Pei, L.R.1
Choi, J.H.2
Liu, J.M.3
Lee, E.J.4
McCarthy, B.5
Wilson, J.M.6
-
49
-
-
77950910741
-
Epigenetic inactivation of the miR-34a in hematological malignancies
-
PMID:20118199
-
Chim CS, Wong KY, Qi Y, Loong F, Lam WL, Wong LG, et al. Epigenetic inactivation of the miR-34a in hematological malignancies. Carcinogenesis 2010; 31:745-50; PMID:20118199; http://dx.doi. org/10.1093/carcin/bgq033.
-
(2010)
Carcinogenesis
, vol.31
, pp. 745-750
-
-
Chim, C.S.1
Wong, K.Y.2
Qi, Y.3
Loong, F.4
Lam, W.L.5
Wong, L.G.6
-
50
-
-
79955526497
-
Epigenetic inactivation of the miR-124-1 in haematological malignancies
-
PMID:21544199
-
Wong KY, So CC, Loong F, Chung LP, Lam WW, Liang R, et al. Epigenetic inactivation of the miR-124-1 in haematological malignancies. PLoS One 2011; 6:e19027; PMID:21544199; http://dx.doi. org/10.1371/journal.pone.0019027.
-
(2011)
PLoS One
, vol.6
-
-
Wong, K.Y.1
So, C.C.2
Loong, F.3
Chung, L.P.4
Lam, W.W.5
Liang, R.6
-
51
-
-
84864856010
-
Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia
-
PMID:22710432
-
Baer C, Claus R, Frenzel LP, Zucknick M, Park YJ, Gu L, et al. Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia. Cancer Res 2012; 72:3775-85; PMID:22710432; http://dx.doi.org/10.1158/0008-5472.CAN-12-0803.
-
(2012)
Cancer Res
, vol.72
, pp. 3775-3785
-
-
Baer, C.1
Claus, R.2
Frenzel, L.P.3
Zucknick, M.4
Park, Y.J.5
Gu, L.6
-
52
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
PMID:12434020
-
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002; 99:15524-9; PMID:12434020; http://dx.doi. org/10.1073/pnas.242606799.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
-
53
-
-
34547854381
-
The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia
-
PMID:17707831
-
Calin GA, Pekarsky Y, Croce CM. The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia. Best Pract Res Clin Haematol 2007; 20:425-37; PMID:17707831; http:// dx.doi.org/10.1016/j.beha.2007.02.003.
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, pp. 425-437
-
-
Calin, G.A.1
Pekarsky, Y.2
Croce, C.M.3
-
54
-
-
36149000639
-
MicroRNAs in the pathogeny of chronic lymphocytic leukaemia
-
PMID:18021085
-
Nicoloso MS, Kipps TJ, Croce CM, Calin GA. MicroRNAs in the pathogeny of chronic lymphocytic leukaemia. Br J Haematol 2007; 139:709-16; PMID:18021085; http://dx.doi.org/10.1111/j.1365-2141.2007.06868.x.
-
(2007)
Br J Haematol
, vol.139
, pp. 709-716
-
-
Nicoloso, M.S.1
Kipps, T.J.2
Croce, C.M.3
Calin, G.A.4
-
55
-
-
70449713652
-
Karyotype-specific microRNA signature in chronic lymphocytic leukemia
-
PMID:19717645
-
Visone R, Rassenti LZ, Veronese A, Taccioli C, Costinean S, Aguda BD, et al. Karyotype-specific microRNA signature in chronic lymphocytic leukemia. Blood 2009; 114:3872-9; PMID:19717645; http:// dx.doi.org/10.1182/blood-2009-06-229211.
-
(2009)
Blood
, vol.114
, pp. 3872-3879
-
-
Visone, R.1
Rassenti, L.Z.2
Veronese, A.3
Taccioli, C.4
Costinean, S.5
Aguda, B.D.6
-
56
-
-
73649116987
-
The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
-
PMID:20060366
-
Klein U, Lia M, Crespo M, Siegel R, Shen Q, Mo T, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell 2010; 17:28-40; PMID:20060366; http://dx.doi.org/10.1016/j. ccr.2009.11.019.
-
(2010)
Cancer Cell
, vol.17
, pp. 28-40
-
-
Klein, U.1
Lia, M.2
Crespo, M.3
Siegel, R.4
Shen, Q.5
Mo, T.6
-
57
-
-
70350511471
-
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): Dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
-
PMID:19643983
-
Zenz T, Häbe S, Denzel T, Mohr J, Winkler D, Bühler A, et al. Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial. Blood 2009; 114:2589-97; PMID:19643983; http://dx.doi.org/10.1182/blood-2009-05-224071.
-
(2009)
Blood
, vol.114
, pp. 2589-2597
-
-
Zenz, T.1
Häbe, S.2
Denzel, T.3
Mohr, J.4
Winkler, D.5
Bühler, A.6
-
58
-
-
82155184350
-
Epigenetic inactivation of the hsa-miR-203 in haematological malignancies
-
PMID:21323860
-
Chim CS, Wong KY, Leung CY, Chung LP, Hui PK, Chan SY, et al. Epigenetic inactivation of the hsa-miR-203 in haematological malignancies. J Cell Mol Med 2011; 15:2760-7; PMID:21323860; http:// dx.doi.org/10.1111/j.1582-4934.2011.01274.x.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 2760-2767
-
-
Chim, C.S.1
Wong, K.Y.2
Leung, C.Y.3
Chung, L.P.4
Hui, P.K.5
Chan, S.Y.6
-
59
-
-
70350452269
-
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia
-
PMID:19692702
-
Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, et al. miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood 2009; 114:3255-64; PMID:19692702; http://dx.doi.org/10.1182/blood-2009-06-229898.
-
(2009)
Blood
, vol.114
, pp. 3255-3264
-
-
Pallasch, C.P.1
Patz, M.2
Park, Y.J.3
Hagist, S.4
Eggle, D.5
Claus, R.6
-
60
-
-
74049141478
-
Epigenetics in cancer
-
PMID:19752007
-
Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis 2010; 31:27-36; PMID:19752007; http://dx.doi.org/10.1093/carcin/bgp220.
-
(2010)
Carcinogenesis
, vol.31
, pp. 27-36
-
-
Sharma, S.1
Kelly, T.K.2
Jones, P.A.3
-
61
-
-
69449100327
-
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia
-
PMID:19666576
-
Chen SS, Raval A, Johnson AJ, Hertlein E, Liu TH, Jin VX, et al. Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2009; 106:13433-8; PMID:19666576; http://dx.doi. org/10.1073/pnas.0906455106.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13433-13438
-
-
Chen, S.S.1
Raval, A.2
Johnson, A.J.3
Hertlein, E.4
Liu, T.H.5
Jin, V.X.6
-
62
-
-
70449971227
-
Epigenetic alterations in a murine model for chronic lymphocytic leukemia
-
PMID:19901553
-
Chen SS, Sherman MH, Hertlein E, Johnson AJ, Teitell MA, Byrd JC, et al. Epigenetic alterations in a murine model for chronic lymphocytic leukemia. Cell Cycle 2009; 8:3663-7; PMID:19901553; http:// dx.doi.org/10.4161/cc.8.22.9957.
-
(2009)
Cell Cycle
, vol.8
, pp. 3663-3667
-
-
Chen, S.S.1
Sherman, M.H.2
Hertlein, E.3
Johnson, A.J.4
Teitell, M.A.5
Byrd, J.C.6
-
63
-
-
36349025291
-
Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival
-
PMID:17666364
-
Stilgenbauer S, Sander S, Bullinger L, Benner A, Leupolt E, Winkler D, et al. Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival. Haematologica 2007; 92:1242-5; PMID:17666364; http://dx.doi. org/10.3324/haematol.10720.
-
(2007)
Haematologica
, vol.92
, pp. 1242-1245
-
-
Stilgenbauer, S.1
Sander, S.2
Bullinger, L.3
Benner, A.4
Leupolt, E.5
Winkler, D.6
-
64
-
-
79961059215
-
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
-
PMID:21546498
-
Gunnarsson R, Mansouri L, Isaksson A, Göransson H, Cahill N, Jansson M, et al. Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica 2011; 96:1161-9; PMID:21546498; http://dx.doi.org/10.3324/haematol. 2010.039768.
-
(2011)
Haematologica
, vol.96
, pp. 1161-1169
-
-
Gunnarsson, R.1
Mansouri, L.2
Isaksson, A.3
Göransson, H.4
Cahill, N.5
Jansson, M.6
-
65
-
-
61349112251
-
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
-
PMID:18713946
-
Sander S, Bullinger L, Klapproth K, Fiedler K, Kestler HA, Barth TF, et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 2008; 112:4202-12; PMID:18713946; http://dx.doi. org/10.1182/blood-2008-03-147645.
-
(2008)
Blood
, vol.112
, pp. 4202-4212
-
-
Sander, S.1
Bullinger, L.2
Klapproth, K.3
Fiedler, K.4
Kestler, H.A.5
Barth, T.F.6
-
66
-
-
78149285100
-
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2
-
PMID:20935635
-
Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, et al. Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol 2010; 12:1108-14; PMID:20935635; http:// dx.doi.org/10.1038/ncb2116.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1108-1114
-
-
Chen, S.1
Bohrer, L.R.2
Rai, A.N.3
Pan, Y.4
Gan, L.5
Zhou, X.6
-
67
-
-
77955085750
-
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
-
PMID:20601953
-
Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010; 42:722-6; PMID:20601953; http:// dx.doi.org/10.1038/ng.621.
-
(2010)
Nat Genet
, vol.42
, pp. 722-726
-
-
Ernst, T.1
Chase, A.J.2
Score, J.3
Hidalgo-Curtis, C.E.4
Bryant, C.5
Jones, A.V.6
-
68
-
-
79953176952
-
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
-
PMID:21399634
-
Yan XJ, Xu J, Gu ZH, Pan CM, Lu G, Shen Y, et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet 2011; 43:309-15; PMID:21399634; http://dx.doi.org/10.1038/ng.788.
-
(2011)
Nat Genet
, vol.43
, pp. 309-315
-
-
Yan, X.J.1
Xu, J.2
Gu, Z.H.3
Pan, C.M.4
Lu, G.5
Shen, Y.6
-
69
-
-
21244446956
-
Expression analysis of the epigenetic methyltransferases and methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL)
-
PMID:15467427
-
Kn H, Bassal S, Tikellis C, El-Osta A. Expression analysis of the epigenetic methyltransferases and methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL). Cancer Biol Ther 2004; 3:989-94; PMID:15467427; http:// dx.doi.org/10.4161/cbt.3.10.1137.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 989-994
-
-
Kn, H.1
Bassal, S.2
Tikellis, C.3
El-Osta, A.4
-
70
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
PMID:17890317
-
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A 2007; 104:15805-10; PMID:17890317; http:// dx.doi.org/10.1073/pnas.0707628104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
Liu, Z.4
Zanesi, N.5
Callegari, E.6
-
71
-
-
77955435090
-
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression
-
PMID:20566844
-
Santanam U, Zanesi N, Efanov A, Costinean S, Palamarchuk A, Hagan JP, et al. Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci U S A 2010; 107:12210-5; PMID:20566844; http://dx.doi. org/10.1073/pnas.1007186107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12210-12215
-
-
Santanam, U.1
Zanesi, N.2
Efanov, A.3
Costinean, S.4
Palamarchuk, A.5
Hagan, J.P.6
-
72
-
-
84863012417
-
Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia
-
PMID:22096249
-
Sampath D, Liu C, Vasan K, Sulda M, Puduvalli VK, Wierda WG, et al. Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia. Blood 2012; 119:1162-72; PMID:22096249; http://dx.doi.org/10.1182/blood-2011-05-351510.
-
(2012)
Blood
, vol.119
, pp. 1162-1172
-
-
Sampath, D.1
Liu, C.2
Vasan, K.3
Sulda, M.4
Puduvalli, V.K.5
Wierda, W.G.6
-
73
-
-
84863138658
-
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)
-
PMID:22308499
-
Palamarchuk A, Yan PS, Zanesi N, Wang L, Rodrigues B, Murphy M, et al. Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL). Proc Natl Acad Sci U S A 2012; 109:2555-60; PMID:22308499; http://dx.doi. org/10.1073/pnas.1200003109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2555-2560
-
-
Palamarchuk, A.1
Yan, P.S.2
Zanesi, N.3
Wang, L.4
Rodrigues, B.5
Murphy, M.6
-
74
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
PMID:17687327
-
Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 2007; 448:714-7; PMID:17687327; http://dx.doi. org/10.1038/nature05987.
-
(2007)
Nature
, vol.448
, pp. 714-717
-
-
Ooi, S.K.1
Qiu, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
-
75
-
-
84863847397
-
Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL
-
PMID:22151263
-
Amin S, Walsh M, Wilson C, Parker AE, Oscier D, Willmore E, et al. Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL. J Cell Mol Med 2012; 16:2074-84; PMID:22151263; http://dx.doi. org/10.1111/j.1582-4934.2011.01503.x.
-
(2012)
J Cell Mol Med
, vol.16
, pp. 2074-2084
-
-
Amin, S.1
Walsh, M.2
Wilson, C.3
Parker, A.E.4
Oscier, D.5
Willmore, E.6
-
76
-
-
79951497639
-
Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications
-
PMID:21139082
-
Billot K, Soeur J, Chereau F, Arrouss I, Merle-Béral H, Huang ME, et al. Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications. Blood 2011; 117:1917-27; PMID:21139082; http://dx.doi.org/10.1182/blood-2010-09-307140.
-
(2011)
Blood
, vol.117
, pp. 1917-1927
-
-
Billot, K.1
Soeur, J.2
Chereau, F.3
Arrouss, I.4
Merle-Béral, H.5
Huang, M.E.6
-
77
-
-
78751682784
-
Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL
-
PMID:21098398
-
Chen SS, Claus R, Lucas DM, Yu L, Qian J, Ruppert AS, et al. Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL. Blood 2011; 117:862-71; PMID:21098398; http://dx.doi.org/10.1182/blood-2010-05-284638.
-
(2011)
Blood
, vol.117
, pp. 862-871
-
-
Chen, S.S.1
Claus, R.2
Lucas, D.M.3
Yu, L.4
Qian, J.5
Ruppert, A.S.6
-
78
-
-
34250658446
-
Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia
-
PMID:17545520
-
Motiwala T, Majumder S, Kutay H, Smith DS, Neuberg DS, Lucas DM, et al. Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia. Clin Cancer Res 2007; 13:3174-81; PMID:17545520; http://dx.doi. org/10.1158/1078-0432.CCR-06-1720.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3174-3181
-
-
Motiwala, T.1
Majumder, S.2
Kutay, H.3
Smith, D.S.4
Neuberg, D.S.5
Lucas, D.M.6
-
79
-
-
83055186737
-
AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia
-
PMID:22001392
-
Motiwala T, Zanesi N, Datta J, Roy S, Kutay H, Checovich AM, et al. AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood 2011; 118:6132-40; PMID:22001392; http://dx.doi. org/10.1182/blood-2011-01-323147.
-
(2011)
Blood
, vol.118
, pp. 6132-6140
-
-
Motiwala, T.1
Zanesi, N.2
Datta, J.3
Roy, S.4
Kutay, H.5
Checovich, A.M.6
-
80
-
-
84875223264
-
Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment
-
In Press; PMID:22828442
-
Moreno P, Abreu C, Borge M, Morande P, Pegazzano M, Palacios F, et al. Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment. Leukemia 2012; In Press; PMID:22828442; http://dx.doi.org/10.1038/leu.2012.212.
-
(2012)
Leukemia
-
-
Moreno, P.1
Abreu, C.2
Borge, M.3
Morande, P.4
Pegazzano, M.5
Palacios, F.6
-
81
-
-
79961085844
-
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
-
PMID:21508119
-
Kaderi MA, Kanduri M, Buhl AM, Sevov M, Cahill N, Gunnarsson R, et al. LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia. Haematologica 2011; 96:1153-60; PMID:21508119; http://dx.doi. org/10.3324/haematol.2010.039396.
-
(2011)
Haematologica
, vol.96
, pp. 1153-1160
-
-
Kaderi, M.A.1
Kanduri, M.2
Buhl, A.M.3
Sevov, M.4
Cahill, N.5
Gunnarsson, R.6
-
82
-
-
84872342533
-
Cellular origin and pathophysiology of chronic lymphocytic leukemia
-
PMID:23091163
-
Seifert M, Sellmann L, Bloehdorn J, Wein F, Stilgenbauer S, Dürig J, et al. Cellular origin and pathophysiology of chronic lymphocytic leukemia. J Exp Med 2012; 209:2183-98; PMID:23091163; http://dx.doi.org/10.1084/jem.20120833.
-
(2012)
J Exp Med
, vol.209
, pp. 2183-2198
-
-
Seifert, M.1
Sellmann, L.2
Bloehdorn, J.3
Wein, F.4
Stilgenbauer, S.5
Dürig, J.6
-
83
-
-
33645513159
-
CLLU1 expression levels predict time to initiation of therapy and overall survival in chronic lymphocytic leukemia
-
PMID:16529606
-
Buhl AM, Jurlander J, Geisler CH, Pedersen LB, Andersen MK, Josefsson P, et al. CLLU1 expression levels predict time to initiation of therapy and overall survival in chronic lymphocytic leukemia. Eur J Haematol 2006; 76:455-64; PMID:16529606; http://dx.doi. org/10.1111/j.0902-4441.2005.t01-1-EJH2530.x.
-
(2006)
Eur J Haematol
, vol.76
, pp. 455-464
-
-
Buhl, A.M.1
Jurlander, J.2
Geisler, C.H.3
Pedersen, L.B.4
Andersen, M.K.5
Josefsson, P.6
-
84
-
-
79960353160
-
Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
-
PMID:21670202
-
Fabbri G, Rasi S, Rossi D, Trifonov V, Khiabanian H, Ma J, et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med 2011; 208:1389-401; PMID:21670202; http://dx.doi.org/10.1084/ jem.20110921.
-
(2011)
J Exp Med
, vol.208
, pp. 1389-1401
-
-
Fabbri, G.1
Rasi, S.2
Rossi, D.3
Trifonov, V.4
Khiabanian, H.5
Ma, J.6
-
85
-
-
85047695306
-
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer
-
PMID:12082632
-
Kleer CG, Zhang Y, Pan Q, van Golen KL, Wu ZF, Livant D, et al. WISP3 is a novel tumor suppressor gene of inflammatory breast cancer. Oncogene 2002; 21:3172-80; PMID:12082632; http://dx.doi. org/10.1038/sj.onc.1205462.
-
(2002)
Oncogene
, vol.21
, pp. 3172-3180
-
-
Kleer, C.G.1
Zhang, Y.2
Pan, Q.3
van Golen, K.L.4
Wu, Z.F.5
Livant, D.6
-
86
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
PMID:8493574
-
Latif F, Tory K, Gnarra J, Yao M, Duh FM, Orcutt ML, et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 1993; 260:1317-20; PMID:8493574; http://dx.doi.org/10.1126/science. 8493574.
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
Yao, M.4
Duh, F.M.5
Orcutt, M.L.6
-
87
-
-
46249095801
-
Insulin receptor substrate protein 53 (IRSp53) as a binding partner of antimetastasis molecule NESH, a member of Abelson interactor protein family
-
PMID:18480067
-
Matsuda S, Yokozaki S, Yoshida H, Kitagishi Y, Shirafuji N, Okumura N. Insulin receptor substrate protein 53 (IRSp53) as a binding partner of antimetastasis molecule NESH, a member of Abelson interactor protein family. Ann Oncol 2008; 19:1356-7; PMID:18480067; http://dx.doi.org/10.1093/annonc/ mdn293.
-
(2008)
Ann Oncol
, vol.19
, pp. 1356-1357
-
-
Matsuda, S.1
Yokozaki, S.2
Yoshida, H.3
Kitagishi, Y.4
Shirafuji, N.5
Okumura, N.6
-
88
-
-
79953822796
-
MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia
-
PMID:21296997
-
Vargova K, Curik N, Burda P, Basova P, Kulvait V, Pospisil V, et al. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. Blood 2011; 117:3816-25; PMID:21296997; http:// dx.doi.org/10.1182/blood-2010-05-285064.
-
(2011)
Blood
, vol.117
, pp. 3816-3825
-
-
Vargova, K.1
Curik, N.2
Burda, P.3
Basova, P.4
Kulvait, V.5
Pospisil, V.6
-
89
-
-
77958164865
-
LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis
-
PMID:20595513
-
Gutierrez A Jr., Tschumper RC, Wu X, Shanafelt TD, Eckel-Passow J, Huddleston PM 3rd, et al. LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis. Blood 2010; 116:2975-83; PMID:20595513; http://dx.doi.org/10.1182/blood-2010-02-269878.
-
(2010)
Blood
, vol.116
, pp. 2975-2983
-
-
Gutierrez Jr., A.1
Tschumper, R.C.2
Wu, X.3
Shanafelt, T.D.4
Eckel-Passow, J.5
Huddleston III, P.M.6
-
90
-
-
77956309330
-
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia
-
PMID:20636436
-
Moreno DA, Scrideli CA, Cortez MA, de Paula Queiroz R, Valera ET, da Silva Silveira V, et al. Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia. Br J Haematol 2010; 150:665-73; PMID:20636436; http://dx.doi.org/10.1111/j.1365-2141.2010.08301.x.
-
(2010)
Br J Haematol
, vol.150
, pp. 665-673
-
-
Moreno, D.A.1
Scrideli, C.A.2
Cortez, M.A.3
de Paula Queiroz, R.4
Valera, E.T.5
da Silva Silveira, V.6
|