메뉴 건너뛰기




Volumn 1, Issue 1, 2009, Pages 39-61

Large-scale analysis of DNA methylation in chronic lymphocytic leukemia

Author keywords

CD38 expression; CLL; DNA methylation; Epigenetics; Leukemia

Indexed keywords

ADAM 12 PROTEIN; ADAM PROTEIN; CD38 ANTIGEN; DLEU7 PROTEIN, HUMAN; DNA; MEMBRANE PROTEIN; NEUROPILIN 2; SFRP2 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

EID: 77954126563     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.09.10     Document Type: Article
Times cited : (49)

References (54)
  • 1
    • 34548511795 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia: Biology and current treatment
    • DOI 10.1007/s11912-007-0046-8
    • Zent CS, Kay NE: Chronic lymphocytic leukemia: biology and current treatment. Curr. Oncol. Rep. 9, 345-352 (2007). (Pubitemid 47377065)
    • (2007) Current Oncology Reports , vol.9 , Issue.5 , pp. 345-352
    • Zent, C.S.1    Kay, N.E.2
  • 5
    • 63349094915 scopus 로고    scopus 로고
    • Expression levels of CD38 on leukemic B cells but not on non-leukemic T cells are comparably stable over time and predict the course of disease in patients with chronic lymphocytic leukemia
    • Eisele L, Haddad T, Sellmann L., Duhrsen U, DurigJ: Expression levels of CD38 on leukemic B cells but not on non-leukemic T cells are comparably stable over time and predict the course of disease in patients with chronic lymphocytic leukemia. Leuk. Res. 33, 775-778 (2009).
    • (2009) Leuk. Res. , vol.33 , pp. 775-778
    • Eisele, L.1    Haddad, T.2    Sellmann, L.3    Duhrsen, U.4    Durig, J.5
  • 6
    • 0036464608 scopus 로고    scopus 로고
    • CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease
    • DOI 10.1182/blood.V99.3.1023
    • Hamblin TJ, Orchard JA, Ibbotson RE et al.: CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood 99 1023-1029 (2002). (Pubitemid 34525567)
    • (2002) Blood , vol.99 , Issue.3 , pp. 1023-1029
    • Hamblin, T.J.1    Orchard, J.A.2    Ibbotson, R.E.3    Davis, Z.4    Thomas, P.W.5    Stevenson, F.K.6    Oscier, D.G.7
  • 7
    • 23844444499 scopus 로고    scopus 로고
    • H gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia
    • DOI 10.1385/MO:22:3:217
    • Tobin G, Rosenquist R: Prognostic usage of VH gene mutation status and its surrogate markers and the role of antigen selection in chronic lymphocytic leukemia. Med. Oncol. 22, 217-228 (2005). (Pubitemid 41176317)
    • (2005) Medical Oncology , vol.22 , Issue.3 , pp. 217-228
    • Tobin, G.1    Rosenquist, R.2
  • 8
    • 28544442915 scopus 로고    scopus 로고
    • CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation
    • DOI 10.1038/sj.leu.2403975, PII 2403975
    • Pittner BT, Shanafelt TD, Kay N.E., Jelinek DF: CD38 expression levels in chronic lymphocytic leukemia B cells are associated with activation marker expression and differential responses to interferon stimulation. Leukemia 19, 2264-2272 (2005). (Pubitemid 41741623)
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2264-2272
    • Pittner, B.T.1    Shanafelt, T.D.2    Kay, N.E.3    Jelinek, D.F.4
  • 10
    • 0026099450 scopus 로고
    • Relationship between CD45 antigen expression and putative stages of differentiation in B-cell Malignancies' am
    • Caldwell CW, Patterson WP: Relationship between CD45 antigen expression and putative stages of differentiation in B-cell malignancies' Am. J. Hematol. 36, 111-115 (1991).
    • (1991) J. Hematol. , vol.36 , pp. 111-115
    • Caldwell, C.W.1    Patterson, W.P.2
  • 12
    • 84873658219 scopus 로고
    • Point estimation of the odds ratio in sparse 2×2 contingency tables
    • MacNeill IB, Umphrey GJ, Reidel D (Eds.)
    • Walter SD: Point estimation of the odds ratio in sparse 2×2 contingency tables. In: Biostatistics. MacNeill IB, Umphrey GJ, Reidel D (Eds.), 71-102 (1987)
    • (1987) Biostatistics , pp. 71-102
    • Walter, S.D.1
  • 13
    • 34548734299 scopus 로고    scopus 로고
    • Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing
    • DOI 10.1158/0008-5472.CAN-07-1016
    • Taylor KH, Kramer RS, Davis JW et al.: Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing. Cancer Res. 67, 8511-8518(2007). (Pubitemid 47437425)
    • (2007) Cancer Research , vol.67 , Issue.18 , pp. 8511-8518
    • Taylor, K.H.1    Kramer, R.S.2    Davis, J.W.3    Guo, J.4    Duff, D.J.5    Xu, D.6    Caldwell, C.W.7    Shi, H.8
  • 14
    • 52649143664 scopus 로고    scopus 로고
    • Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic Leukemia
    • Rassenti LZ, Jain S, Keating MJ et al.: Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia. Blood 112, 1923-1930 (2008).
    • (2008) Blood , vol.112 , pp. 1923-1930
    • Rassenti, L.Z.1    Jain, S.2    Keating, M.J.3
  • 16
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and integrated discovery
    • Dennis Jr. G, Sherman BT, Hosack DA et al.: DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, 3(2003).
    • (2003) Genome Biol. , vol.4 , pp. 3
    • Dennis Jr., G.1    Sherman, B.T.2    Hosack, D.A.3
  • 18
    • 0024272160 scopus 로고
    • Hypomethylation of ornithine decarboxylase gene and Erb-A1 oncogene in human chronic lymphatic leukemia
    • Upsanen V, Leinonen P, Alhonen L., Janne J: Hypomethyl ation of ornithine decarboxylase gene and erb-Al oncogene in human chronic lymphatic leukemia. Blood 11, 2042-2044 (1988). (Pubitemid 19030896)
    • (1988) Blood , vol.72 , Issue.6 , pp. 2042-2044
    • Lipsanen, V.1    Leinonen, P.2    Alhonen, L.3    Janne, J.4
  • 20
    • 0027239823 scopus 로고
    • Bcl-2 Gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • Hanada M, Delia D, Aiello A., Stadtmauer E, Reed JC: BCL-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82, 1820-1828 (1993). (Pubitemid 23278773)
    • (1993) Blood , vol.82 , Issue.6 , pp. 1820-1828
    • Hanada, M.1    Delia, D.2    Aiello, A.3    Stadtmauer, E.4    Reed, J.C.5
  • 25
    • 17044406054 scopus 로고    scopus 로고
    • CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival
    • Deaglio S, Vaisitti T, Bergui L et al.: CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival. Blood 105, 3042-3050 (2005).
    • (2005) Blood , vol.105 , pp. 3042-3050
    • Deaglio, S.1    Vaisitti, T.2    Bergui, L.3
  • 27
    • 0037346351 scopus 로고    scopus 로고
    • Simultaneous expression of CD38 and its ligand CD31 by chronic lymphocytic Leukemia B-cells: Anecdotal observation or pathogenetic hypothesis for the clinical outcome?
    • Morabito F, Mangiola M, Stelitano C., Deaglio S, Callea V, Malavasi F: Simultaneous expression of CD38 and its ligand CD31 by chronic lymphocytic leukemia B-cells: anecdotal observation or pathogenetic hypothesis for the clinical outcome? Haematologica 88, 354-355 (2003).
    • (2003) Haematologica , vol.88 , pp. 354-355
    • Morabito, F.1    Mangiola, M.2    Stelitano, C.3    Deaglio, S.4    Callea, V.5    Malavasi, F.6
  • 28
    • 14044272782 scopus 로고    scopus 로고
    • CD38 signaling regulates B lymphocyte activation via a phospholipase C (PLC)-y2-independent, protein kinase C, phosphatidylcholine-PLC, and phospholipase D-dependent signaling cascade
    • Moreno-Garcia M.E., Lopez-Bojorques LN, Zentella A., Humphries LA, Rawlings DJ, Santos-Argumedo L: CD38 signaling regulates B lymphocyte activation via a phospholipase C (PLC)-y 2-independent, protein kinase C, phosphatidylcholine-PLC, and phospholipase D-dependent signaling cascade. J. Immunol. 174, 2687-2695 (2005). (Pubitemid 40279683)
    • (2005) Journal of Immunology , vol.174 , Issue.5 , pp. 2687-2695
    • Moreno-Garcia, M.E.1    Lopez-Bojorques, L.N.2    Zentella, A.3    Humphries, L.A.4    Rawlings, D.J.5    Santos-Argumedo, L.6
  • 29
    • 33644912283 scopus 로고    scopus 로고
    • Wnt inhibitory factor-1, a wnt antagonist, is silenced by promoter hypermethylation in Malignant pleural mesothelioma
    • Batra S, Shi Y, Kuchenbecker KM et al.: Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma. Biochem. Biophys. Res. Commun. 342, 1228-1232 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.342 , pp. 1228-1232
    • Batra, S.1    Shi, Y.2    Kuchenbecker, K.M.3
  • 30
    • 36349013133 scopus 로고    scopus 로고
    • Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma
    • DOI 10.1038/sj.leu.2404939, PII 2404939
    • Chim CS, Pang R, Fung T.K., Choi CL, Liang R: Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma. Leukemia 21, 2527-2536 (2007). (Pubitemid 350148897)
    • (2007) Leukemia , vol.21 , Issue.12 , pp. 2527-2536
    • Chim, C.S.1    Pang, R.2    Fung, T.K.3    Choi, C.L.4    Liang, R.5
  • 31
    • 52549133774 scopus 로고    scopus 로고
    • Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia
    • Dhir M, Montgomery EA, Glockner SC et al.: Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. J. Gastrointest. Surg. 12, 1745-1753 (2008).
    • (2008) J. Gastrointest. Surg. , vol.12 , pp. 1745-1753
    • Dhir, M.1    Montgomery, E.A.2    Glockner, S.C.3
  • 32
    • 58149382600 scopus 로고    scopus 로고
    • Constitutive activation of the wnt canonical pathway in mantle cell lymphoma
    • Gelebart P, Anand M, Armanious H et al.: Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood 112, 5171-5179(2008).
    • (2008) Blood , vol.112 , pp. 5171-5179
    • Gelebart, P.1    Anand, M.2    Armanious, H.3
  • 33
    • 33645774983 scopus 로고    scopus 로고
    • Role of WNT signaling in normal and malignant hematopoiesis
    • Khan NI, Bendall LJ: Role of WNT signaling in normal and malignant hematopoiesis. Histol. Histopathol. 21, 761-774 (2006). (Pubitemid 44082718)
    • (2006) Histology and Histopathology , vol.21 , Issue.7-9 , pp. 761-774
    • Khan, N.I.1    Bendall, L.J.2
  • 34
    • 50149117391 scopus 로고    scopus 로고
    • Methylation status of wnt signaling pathway genes affects the clinical outcome of philadelphia-positive acute lymphoblastic Leukemia
    • Martin V, Agirre X, Jimenez-Velasco A et al.: Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia-positive acute lymphoblastic leukemia. Cancer Sci. 99(9), 1865-1868 (2008).
    • (2008) Cancer Sci. , vol.99 , Issue.9 , pp. 1865-1868
    • Martin, V.1    Agirre, X.2    Jimenez-Velasco, A.3
  • 35
    • 0037434982 scopus 로고    scopus 로고
    • Wnt signaling in B-cell neoplasia
    • DOI 10.1038/sj.onc.1206239
    • Qiang YW, Endo Y, Rubin J.S., Rudikoff S: Wnt signaling in B-cell neoplasia. Oncogene 22, 1536-1545 (2003). (Pubitemid 36390603)
    • (2003) Oncogene , vol.22 , Issue.10 , pp. 1536-1545
    • Qiang, Y.-W.1    Endo, Y.2    Rubin, J.S.3    Rudikoff, S.4
  • 38
    • 34247635666 scopus 로고    scopus 로고
    • Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression
    • DOI 10.1038/sj.leu.2404657, PII 2404657
    • Sengupta A, Banerjee D, Chandra S et al.: Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression. Leukemia 21, 949-955 (2007). (Pubitemid 46672071)
    • (2007) Leukemia , vol.21 , Issue.5 , pp. 949-955
    • Sengupta, A.1    Banerjee, D.2    Chandra, S.3    Banerji, S.K.4    Ghosh, R.5    Roy, R.6    Banerjee, S.7
  • 39
    • 36849023295 scopus 로고    scopus 로고
    • DifferentialcControl of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors
    • DOI 10.1128/MCB.00555-07
    • Wohrle S, Wallmen B, Hecht A: Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Mol. Cell Biol. 27, 8164-8177 (2007). (Pubitemid 350234231)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.23 , pp. 8164-8177
    • Wohrle, S.1    Wallmen, B.2    Hecht, A.3
  • 40
    • 33745823867 scopus 로고    scopus 로고
    • Infrequent Wnt inhibitory factor-1 (Wif-1) methylation in chronic lymphocytic leukemia
    • DOI 10.1016/j.leukres.2005.12.005, PII S0145212605004777
    • Chim CS, Fung TK, Wong KF Lau JS, Liang R: Infrequent Wnt inhibitory factor-1 (Wif-1) methylation in chronic lymphocytic leukemia. Leuk. Res. 30(9), 1135-1139 (2006). (Pubitemid 44037081)
    • (2006) Leukemia Research , vol.30 , Issue.9 , pp. 1135-1139
    • Chim, C.S.1    Fung, T.K.2    Wong, K.F.3    Lau, J.S.4    Liang, R.5
  • 41
    • 56049111627 scopus 로고    scopus 로고
    • Epigenetic dysregulation of the wnt signalling pathway in chronic lymphocytic Leukaemia
    • Chim CS, Pang R, Liang R: Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia. J. Clin. Pathol. 61, 1214-1219 (2008).
    • (2008) J. Clin. Pathol. , vol.61 , pp. 1214-1219
    • Chim, C.S.1    Pang, R.2    Liang, R.3
  • 42
    • 27844465017 scopus 로고    scopus 로고
    • Variation of LEF-1 mRNA expression in low-grade B-cell non-Hodgkin's lymphoma
    • DOI 10.1016/j.leukres.2005.06.004, PII S0145212605002183
    • Howe D, Bromidge T: Variation of LEF-1 mRNA expression in low-grade B-cell non-Hodgkin's lymphoma. Leuk. Res. 30, 29-32 (2006). (Pubitemid 41654701)
    • (2006) Leukemia Research , vol.30 , Issue.1 , pp. 29-32
    • Howe, D.1    Bromidge, T.2
  • 43
    • 31544469759 scopus 로고    scopus 로고
    • CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia
    • DOI 10.1158/0008-5472.CAN-05-3712
    • Liu TH, Raval A, Chen S.S., Matkovic JJ, Byrd JC, Plass C: CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. Cancer Res. 66, 653-658 (2006). (Pubitemid 43165926)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 653-658
    • Liu, T.-H.1    Raval, A.2    Chen, S.-S.3    Matkovic, J.J.4    Byrd, J.C.5    Plass, C.6
  • 45
    • 58549110011 scopus 로고    scopus 로고
    • Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of wnt/p-catenin signaling and CLL cell survival
    • Jin G, Lu D, Yao S et al.: Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/p-catenin signaling and CLL cell survival. Bioorg. Med. Chem. Lett. 19, 606-609 (2009).
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 606-609
    • Jin, G.1    Lu, D.2    Yao, S.3
  • 46
    • 41049099329 scopus 로고    scopus 로고
    • Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
    • Geretti E, Shimizu A, Klagsbrun M: Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis. 11, 31-39 (2008).
    • (2008) Angiogenesis , vol.11 , pp. 31-39
    • Geretti, E.1    Shimizu, A.2    Klagsbrun, M.3
  • 47
    • 35449007278 scopus 로고    scopus 로고
    • Angiogenesis revisited in CLL
    • DOI 10.1016/j.leukres.2007.04.001, PII S0145212607001324
    • Kay NE: Angiogenesis revisited in CLL. Leuk. Res. 31, 1459-1460 (2007). (Pubitemid 47632795)
    • (2007) Leukemia Research , vol.31 , Issue.11 , pp. 1459-1460
    • Kay, N.E.1
  • 48
    • 35448974112 scopus 로고    scopus 로고
    • Markers of increased angiogenesis and their correlation with biological parameters identifying high-risk patients in early B-cell chronic lymphocytic leukemia
    • DOI 10.1016/j.leukres.2007.03.009, PII S0145212607001014
    • Molica S, Cutrona G, Vitelli G et al.: Markers of increased angiogenesis and their correlation with biological parameters identifying high-risk patients in early B-cell chronic lymphocytic leukemia. Leuk. Res. 31, 1575-1578 (2007). (Pubitemid 47632791)
    • (2007) Leukemia Research , vol.31 , Issue.11 , pp. 1575-1578
    • Molica, S.1    Cutrona, G.2    Vitelli, G.3    Mirabelli, R.4    Molica, M.5    Digiesi, G.6    Ribatti, D.7    Ferrarini, M.8    Vacca, A.9
  • 49
    • 0347355522 scopus 로고    scopus 로고
    • Characterization of a novel B-CLL candidate gene - DLEU7 - Located in the 13q14 tumor suppressor locus
    • DOI 10.1016/S0014-5793(03)01371-1
    • Hammarsund M, Corcoran MM, Wilson W et al.: Characterization of a novel B-CLL candidate gene - DLEU7- located in the 13ql4 tumor suppressor locus. FEBS Lett. 556(1-3), 75-80 (2004). (Pubitemid 38058558)
    • (2004) FEBS Letters , vol.556 , Issue.1-3 , pp. 75-80
    • Hammarsund, M.1    Corcoran, M.M.2    Wilson, W.3    Zhu, C.4    Einhorn, S.5    Sangfelt, O.6    Grander, D.7
  • 52
    • 33750530675 scopus 로고    scopus 로고
    • Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with Leukemia
    • Garcia-Manero G., Kantarjian HM, Sanchez-Gonzalez B et al.: Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. Blood 108, 3271-3279 (2006).
    • (2006) Blood , vol.108 , pp. 3271-3279
    • Garcia-Manero, G.1    Kantarjian, H.M.2    Sanchez-Gonzalez, B.3
  • 53
    • 31344460650 scopus 로고    scopus 로고
    • Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: Dose, duration, and patient selection
    • Issa JP: Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection. Nat. Clin. Pract. Oncol. 2 (Suppl. 1), S24-S29 (2005).
    • (2005) Nat. Clin. Pract. Oncol. , vol.2 , Issue.SUPPL. 1
    • Issa, J.P.1
  • 54
    • 67349200930 scopus 로고    scopus 로고
    • The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells
    • Flotho C, Claus R, Batz C et al.: The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia 23, 1019-1028 (2009).
    • (2009) Leukemia , vol.23 , pp. 1019-1028
    • Flotho, C.1    Claus, R.2    Batz, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.