AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of leber congenital amaurosis

Human Gene Therapy

Volumn 24, Issue 2, 2013, Pages 189-202

  Boye, Sanford L ^a   Peshenko, Igor V ^b   Huang, Wei Chieh ^c   Min, Seok Hong ^a   McDoom, Issam ^a   Kay, Christine N ^a   Liu, Xuan ^a   Dyka, Frank M ^a   Foster, Thomas C ^a   Umino, Yumiko ^d   Karan, Sukanya ^e   Jacobson, Samuel G ^c   Baehr, Wolfgang ^e   Dizhoor, Alexander ^b   Hauswirth, William W ^a   Boye, Shannon E ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b SALUS UNIVERSITY   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d State University of New York Upstate Medical University: College of Medicine   (United States)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATING PROTEIN 1; GUANYLATE CYCLASE ACTIVATING PROTEIN 2; ISOENZYME; OPSIN; RETINAL GUANYLATE CYCLASE 1; RHODOPSIN KINASE; UNCLASSIFIED DRUG; VISUAL PROTEINS AND PIGMENTS;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE THERAPY; IN VIVO STUDY; LEBER CONGENITAL AMAUROSIS; MOUSE; NONHUMAN; PHOTORECEPTOR; RETINA CONE; RETINA ROD;

ANIMALS; DEPENDOVIRUS; ENZYME ACTIVATION; G-PROTEIN-COUPLED RECEPTOR KINASE 1; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; GUANYLATE CYCLASE; HUMANS; LEBER CONGENITAL AMAUROSIS; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; RECEPTORS, CELL SURFACE; RETINA; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL ROD PHOTORECEPTOR CELLS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84874339776     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2012.193     Document Type: Article

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