Long-term preservation of cone photoreceptors and restoration of cone function by gene therapy in the guanylate cyclase-1 knockout (GC1KO) mouse

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 10, 2011, Pages 7098-7108

  Boye, Sanford L ^a   Conlon, Thomas ^a   Erger, Kirsten ^a   Ryals, Renee ^a   Neeley, Andy ^a   Cossette, Travis ^a   Pang, Jijing ^a   Dyka, Frank M ^a   Hauswirth, William W ^a   Boye, Shannon E ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANYLATE CYCLASE; MESSENGER RNA; PARVOVIRUS VECTOR; CELL SURFACE RECEPTOR; GNAT2 PROTEIN, MOUSE; GRK1 PROTEIN, HUMAN; GUANYLATE CYCLASE 1; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; RHODOPSIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRORETINOGRAPHY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RETINA CONE; RETINA DEGENERATION; VIRAL GENE THERAPY; ADENO ASSOCIATED VIRUS; ANIMAL; CELL SURVIVAL; DISEASE MODEL; FEMALE; GENE THERAPY; GENE VECTOR; GENETICS; INTRAOCULAR DRUG ADMINISTRATION; LEBER CONGENITAL AMAUROSIS; MALE; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL SURVIVAL; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; FEMALE; G-PROTEIN-COUPLED RECEPTOR KINASE 1; GENE THERAPY; GENETIC VECTORS; GUANYLATE CYCLASE; HETEROTRIMERIC GTP-BINDING PROTEINS; INJECTIONS, INTRAOCULAR; LEBER CONGENITAL AMAUROSIS; MALE; MICE; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; RETINAL CONE PHOTORECEPTOR CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 80155125829     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7867     Document Type: Article

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