Phosphatidylinositol 4-Phosphate 5-Kinase α facilitates toll-like receptor 4-mediated microglial inflammation through regulation of the toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) location

Journal of Biological Chemistry

Volumn 288, Issue 8, 2013, Pages 5645-5659

  Nguyen, Tu Thi Ngoc ^a   Kim, Yong Min ^a   Kim, T Doohun ^c   Le, Oanh Thi Tu ^a   Kim, Jae Jin ^d   Kang, Ho Chul ^d   Hasegawa, Hiroshi ^e   Kanaho, Yasunori ^e   Jou, Ilo ^a   Lee, Sang Yoon ^b  

^a Center for Chronic Metabolic Disease Research   (South Korea)

^b Ajou University School of Medicine   (South Korea)

^c Ajou University   (South Korea)

^d Orthopaedic Clinic   (Japan)

^e UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; IMMUNE FUNCTION; INFLAMMATORY RESPONSE; MICROGLIA; MICROGLIAL CELLS; PHOSPHATIDYLINOSITOL 4 PHOSPHATES; PHOSPHOINOSITIDES; TOLL-LIKE RECEPTORS;

PHOSPHOLIPIDS;

CELL MEMBRANES;

I KAPPA B KINASE ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LENTIVIRUS VECTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 5 KINASE ALPHA; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE CONSTRUCT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; MICROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; TRANSCRIPTION INITIATION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; CELL LINE; CELL MEMBRANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEK293 CELLS; HELA CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-1; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; NITRIC OXIDE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 84874303630     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.410126     Document Type: Article

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