Phosphatidylinositol phosphate kinases put PI4,5P2 in its place

Journal of Membrane Biology

Volumn 194, Issue 2, 2003, Pages 77-89

  Doughman, R L ^a   Firestone, A J ^a   Anderson, R A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Arf; Phosphatidylinositol bisphosphate; Phosphatidylinositol phosphate kinases; Rac; Rho; Substrate specificity

Indexed keywords

PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

CELL ACTIVITY; CELLULAR DISTRIBUTION; CYTOSKELETON; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SYNTHESIS; FOCAL ADHESION; REVIEW; SECOND MESSENGER;

ACTINS; ANIMALS; ENZYME ACTIVATION; HUMANS; ISOENZYMES; MONOMERIC GTP-BINDING PROTEINS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0042817834     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-003-2027-7     Document Type: Review

References (83)

1. Anderson, R.A., Boronenkov, I.V., Doughman, S.D., Kunz, J., Loijens, J.C. 1999. Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes. J. Biol. Chem. 274:9907-9910
2. Arneson, L.S., Kunz, J., Anderson, R.A., Traub, L.M. 1999. Coupled inositide phosphorylation and phospholipase D activation initiates clathrin-coat assembly on lysosomes. J. Biol. Chem. 274:17794-17805
3. Auger, K.R., Serunian, L.A., Soltoff, S.P., Libby, P., Cantiey, L.C. 1989. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57:167-175
4. Ayscough, K.R. 1998. In vivo functions of actin-binding proteins. Curr. Opin. Cell Biol. 10:102-111
5. Balla, T., Bondeva, T., Varnai, P. 2000. How accurately can we image inositol lipid in living cells? Trends Pharm. Sci. 21:238-241
6. Barbieri, M.A., Heath, CM., Peters, E.M., Wells, A., Davis, J.N., Stahl, P.D. 2001. Phosphatidylinositol-4-phosphate 5-kinase-1 beta is essential for epidermal growth factor receptor-mediated endocytosis. J. Biol. Chem. 276:47212-47216
7. Boronenkov, I.V., Loijens, J.C., Umeda, M., Anderson, R.A. 1998. Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. Mol. Biol. Cell. 9:3547-3560
8. Brown, F.D., Rozelle, A.L., Yin, H.L., Balla, T., Donaldson, J.G. 2001. Phosphatidylinositol 4,5 bisphosphate and Arf6-regulated membrane traffic. J. Cell. Biol. 154:1007-1017
9. Botelho, R.J., Teruel, M., Dierckman, R., Anderson, R., Wells, A., York, J.D., Meyer, T., Grinstein, S. 2000. Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J. Cell. Biol. 151:1353-1368
10. Castellino, A.M., Parker, G.J., Boronenkov, I.V., Anderson, R.A., Chao, M.V. 1997. A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 272:5861-587
11. Chatah, N.E., Abrams, C.S. 2001. G-protein-coupled receptor activation induces the membrane translocation and activation of phosphatidylinositol-4-phosphate 5-kinase I alpha by a Rac-and Rho-dependent pathway. J. Biol. Chem. 276:34059-34065
12. Chong, L.D., Traynor-Kaplan, A., Bokoch, G.M., Schwartz, M.A. 1994. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79:507-513
13. Cockcroft, S., De Matteis, M.A. 2001. Inositol lipids as spatial regulators of membrane traffic. J. Membrane Biol. 180:187-194
14. Coppolino, M.G., Dierckman, R., Loijens, J., Collins, R.F., Pouladi, M., Jongstra-Bilen, J., Schreiber, A.D., Trimble, W.S., Anderson, R., Grinstein, S. 2002. Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ia impairs localized actin remodelling and suppresses phagocytosis. J. Biol. Chem. 277:43849-43857
15. Czech, M.P. 2000. PI4,5P2 and PI4,5P3: complex roles at the cell surface. Cell 100:603-606
16. Davis, J.N., Rock, C.O., Cheng, M., Watson, J.B., Ashmun, R.A., Kirk, H., Kay, R.J., Roussel, M.F. 1997. Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol-4-phosphate 5-kinase. Mol. Cell Biol. 17:7398-7406
17. Desrivieres, S., Cooke, F.T., Parker, P.J., Hall, M.N. 1998. MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. J. Biol. Chem. 273:15787-15793
18. DeWald, D. 2002. Phosphoinositide signaling: vac to the future in fabl kinase regulation. Curr. Biol. 12:R491-R492
19. Di Paolo, G., Pellegrini, L., Letinic, K., Cestra, G., Zoncu, R., Voronov, S., Chang, S., Guo, J., Wenk, M.R., De Camilli, P. 2002. Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature 420:85-89
20. Gary, J.D., Wurmser, A.E., Bonangelino, C.J., Weisman, L.S., Emr, S.D. 1998. Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vascuolar size and membrane homeostasis. J. Cell Biol. 143:65-79
21. Gilmore, A.P., Burridge, K. 1996. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate. Nature 381:531-535
22. Godi, A., Pertile, P., Meyers, R., Marra, P., Di Tullio, G., Iurisci, C., Luini, A., Corda, D., De Matteis, M.A. 1999. ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of Ptdlns(4,5)P2 on the Golgi complex. Nat. Cell Biol. 1:280-287
23. Halstead, J.R., Roefs, M., Ellson, C.D., D'Andrea, S., Chen, C., D'Santos, C.S., Divecha, N. 2001. A novel pathway of cellular phosphatidylinositol(3,4,5)-trisphosphate synthesis is regulated by oxidative stress. Curr. Biol. 11:386-395
24. Hartwig, J.H., Kwiatkowski, D.J. 1991. Actin-binding proteins. Curr. Opin. Cell Biol. 3:87-97
25. 2+-activated secretion. Nature 374:173-177
26. Higgs, H.N., Pollard, T.D. 2000. Activation by Cdc42 and PI4,5P(2) of Wiskott Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex. J. Cell Biol. 150:1311-1320
27. Homma, K., Terui, S., Minemura, M., Qadota, H., Anraku, Y., Kanaho, Y., Ohya, Y. 1998. Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis. J. Biol. Chem. 273:15779-15786
28. Honda, A., Nogami, M., Yokozeki, T., Yamazaki, M., Nakamura, H., Watanabe, H., Kawamoto, K., Nakayama, K., Morris, A.J., Frohman, M.A., Kanaho, Y. 1999. Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell 99:521-532
29. Ikonomov, O.C., Sbrissa, D., Mlak, K., Kanzaki, M., Pessin, J., Shisheva, A. 2002. Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity. J. Biol. Chem. 277:9206-9211
30. Ishihara, H., Shibasaki, Y., Kizuki, N., Katagiri, H., Yazaki, Y., Asano, T., Oka, Y. 1996. Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 271:23611-23614
31. Ishihara, H., Shibasaki, Y., Kizuki, N., Wada, T., Yazaki, Y., Asano, T., Oka, Y. 1998. Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. J. Biol. Chem. 273:8741-8748
32. Itoh, T., Ijuin, T., Takenawa, T. 1998. A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase Ilgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signals. J. Biol. Chem. 273:20292-20299
33. Itoh, T., Ishihara, H., Shibasaki, Y., Oka, Y., Takenawa, T. 2000. Autophosphorylation of type I phosphatidylinositol phosphate kinase regulates its lipid kinase activity. J. Biol. Chem. 275:19389-19394
34. Jenkins, G.H., Fisette, P.L., Anderson, R.A. 1994. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269:11547-11554
35. Johnson, R.P., Craig, S.W. 2000. Actin activates a cryptic dimerization potential of the vinculin tail domain. J. Biol. Chem. 275:95-105
36. Jones, D.R., Sanjuan, M.A., Merida, I. 2000. Type Ialpha phosphatidylinositol 4-phosphate 5-kinase is a putative target for increased intracellular phosphatidic acid. FEBS Lett. 476:160-165
37. Kunz, J., Fuelling, A., Kolbe, L., Anderson, R.A. 2002. Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residue. J. Biol. Chem. 277:5611-5619
38. Kunz, J., Wilson, M.P., Kisseleva, M., Hurley, J.H., Majerus, P.W., Anderson, R.A. 2000. The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol. Cell 5:1-11
39. Lauffenburger, D.A., Horwitz, A.F. 1996. Cell migration: a physically integrated molecular process. Cell 84:359-369
40. Lee, E., De Camilli, P. 2002. Dynamin at actin tails. Proc. Natl. Acad. Sci. U SA 99:161-166
41. Ling, K., Doughman, R.L., Firestone, A.J., Bunce, M.W., Anderson, R.A. 2002. Type 1gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature 420:89-93
42. Loijens, J.C., Anderson, R.A. 1996. Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family. J. Biol. Chem. 271:32937-32943
43. Maekawa, M., Eshizaki, T., Boku, S., Watanabe, N., Fujita, A., Iwamatsu, A., Obinata, T., Ohashi, K., Mizuno, K., Narumiya, S. 1999. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285:895-898
44. Martin, T.F. 2001. PI(4,5)P(2) regulation of surface membrane traffic. Curr. Opin. Cell Biol. 13:493-499
45. Matsui, T., Yonemura, S., Tsukita, S. 1999. Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases. Curr. Biol. 9:1259-1262
46. McEwen, R.K., Dove, S.K., Cooke, F.T., Painter, G.F., Holmes, A.B., Shisheva, A., Ohya, Y., Parker, P.J., Michell, R.H. 1999. Complementation analysis in PtdlnsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases. J. Biol. Chem. 274:3905-33912
47. McLaughlin, S., Wang, J., Gambhir, A., Murray, D. 2002. P14,5P(2) and proteins: interactions, organization, and information flow. Annu. Rev. Biophys. Biomol. Struct. 31:151-175
48. Miyazawa, A., Umeda, M., Torikoshi, T., Yanagisawa, K., Yoshioka, T., Inoue, K. 1988. Production and characterization of monoclonal antibodies that bind to phosphatidylinositol 4,5 bisphosphate. Mol. Immunol. 25:1025-1031
49. Nobes, C.D., Hall, A. 1995. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81:53-62
50. Orth, J.D., Krueger, E.W., Cao, H., McNiven, M.A. 2002. The large GTPase dynamin regulates actin comet formation and movement in living cells. Proc. Natl. Acad. Sci. US A 99:167-172
51. Oude Weernink, P.A., Schulte, P., Guo, Y., Wetzel, J., Amano, M., Kaibuchi, K., Haverland, S., Voss, M., Schmidt, M., Mayr, G.W., Jakobs, K.H. 2000. Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase. J. Biol. Chem. 275:10168-10174
52. Park, S.J., Itoh, T., Takenawa, T. 2001. Phosphatidylinositol phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli. J. Biol. Chem. 276:4781-4787
53. Rameh, L.E., Tolias, K.F., Duckworth, B.C., Cantley, L.C. 1997. A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. Nature 390:192-196
54. Randazzo, P.A., Nie, Z., Miura, K., Hsu, V.W. 2000. Molecular aspects of the cellular activities of ADP-ribosylation factors. Sci STKE 2000:RE1
55. Rao, V.D., Misra, S., Boronenkov, I.V., Anderson, R.A., Hurley, J.H. 1998. Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell 94:829-839
56. Ren, X.D., Bokoch, G.M., Traynor-Kaplan, A., Jenkins, G.H., Anderson, R.A., Schwartz, M.A. 1996. Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells. Mol. Biol. Cell 7:435-442
57. Rohatgi, R., Ho, H.Y., Kirschner, M.W. 2000. Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate. J. Cell Biol. 150:1299-1310
58. Rozelle, A.L., Machesky, L.M., Yamamoto, M., Driessens, M.H., Insall, R.H., Roth, M.G., Luby-Phelps, K., Marriott, G., Hall, A., Yin, H.L. 2000. Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3. Curr. Biol. 10:311-320
59. Sbrissa, D., Ikonomov, O.C., Shisheva, A. 1999. PIKfyve, a mammalian ortholog of yeast Fablp lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin. J. Biol. Chem. 274:21589-21597
60. Sbrissa, D., Ikonomov, O.C., Shisheva, A. 2002. Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomembrane localization. J. Biol. Chem. 277:6073-6079
61. Sechi, A.S., Wehland, J. 2000. The actin cytoskeleton and plasma membrane connection: Ptdlns(4,5)P(2) influences cytoskeletal protein activity at the plasma membrane. J. Cell Sci. 113:3685-3695
62. Shibasaki, Y., Ishihara, H., Kizuki, N., Asano, T., Oka, Y., Yazaki, Y. 1997. Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo. J. Biol. Chem. 212:7578-7581
63. Shyng, S.L., Barbieri, A., Gumusboga, A., Cukras, C., Pike, L., Davis, J.N., Stahl, P.D., Nichols, C.G. 2000. Modulation of nucleotide sensitivity of ATP-sensitive potassium channels by phosphatidylinositol-4-phosphate 5-kinase. Proc. Natl. Acad. Sci. USA 97:937-941
64. Skippen, A., Jones, D.H., Morgan, C.P., Li, M., Cockcroft, S. 2002. Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells. J. Biol. Chem. 277:5823-5831
65. Small, J.V., Stradal, T., Vignal, E., Rottner, K. 2002. The lamellipodium: where motility begins. Trends Cell Biol. 12:112-120
66. Stripp, C.S., Kolesnikova, T.V., Hemler, M.E. 2003. Functional domains in tetraspanin proteins. Trends Biochem. Sci. 28:106-112
67. Toker, A. 1998. The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate. Curr. Opin. Cell Biol. 10:254-261
68. Tolias, K.F., Cantley, L.C., Carpenter, C.L. 1995. Rho family GTPases bind to phosphoinositide kinases. J. Biol. Chem. 270:17656-17659
69. Tolias, K.F., Couvillon, A.D., Cantley, L.C., Carpenter, C.L. 1998 Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex. Mol. Cell Biol. 18:762-770
70. Tolias, K.F., Rameh, L.E., Ishihara, H., Shibasaki, Y., Chen, J., Prestwich, G.D., Cantley, L.C., Carpenter, C.L. 1998. Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate. J. Biol. Chem. 273:18040-18046
71. Tolias, K.F., Hartwig, J.H., Ishihara, H., Shibasaki, Y., Cantley, L.C., Carpenter, C.L. 2000. Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly. Curr. Biol. 10:153-156
72. Vancurova, I., Choi, J.H., Lin, H., Kuret, J., Vancura, A. 1999. Regulation of phosphatidylinositol 4-phosphate 5-kinase from Schizosaccharomyces pombe by casein kinase I. J. Biol. Chem. 274:1147-1155
73. van Horck, P.P., Lavazais, E., Eickholt, B.J., Moolenaar, W.H., Divecha, N. 2002. Essential role of Type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling. Curr. Biol. 12:241-245
74. Van Rheenen, J., Jalink, K. 2002. Agonist-induced PI4,5P(2) hydrolysis inhibits cortical actin dynamics: Regulation at a global but not at a micrometer scale. Mol. Biol. Cell 13:3257-3267
75. Watt, S.A., Kular, G., Fleming, I.N., Downes, C.P., Lucocq, J.M. 2002. Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta 1. Biochem. J. 363:651-666
76. Weernink, P.A., Guo, Y., Zhang, C., Schmidt, M., Von Eichel-Streiber, C., Jakobs, K.H. 2000. Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and rho GTPases in NIH 3T3 fibroblasts involvement of both phosphatidylinositol-4-phosphate 5-kinase and phospholipase C. Eur. J. Biochem. 267:5237-5246
77. Wenk, M.R., Pellegrini, L., Klenchin, V.A., Di Paolo, G., Chang, S., Daniell, L., Arioka, M., Martin, T.F., De Camilli, P. 2001. P14,5P kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse. Neuron 32:79-88
78. Yamamoto, A., DeWald, D.B., Boronenkov, I.V., Anderson, R.A., Emr, S.D., Koshland, D. 1995. Novel PI(4)P 5-kinase homologue, Fablp, essential for normal vacuole function and morphology in yeast. Mol. J. Biol. Cell 6:525-539
79. Yamanoto, M., Hilgemann, D.H., Feng, S., Bito, H., Ishihara, H., Shibasaki, Y., Yin, H.L. 2001. Phosphatidylinositol 4,5-bisphosphate induces actin stress-fiber formation and inhibits membrane ruffling in CV1 cells. Cell Biol. 152:867-876
80. Yamazaki, M., Miyazaki, H., Watanabe, H., Sasaki, T., Maehama, T., Frohman, M.A., Kanaho, Y. 2002. Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling. J. Biol. Chem. 277:17226-17230
81. York, J.D., Odom, A.R., Murphy, R., Ives, E.B., Wente, S.R. 1999. A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285:96-100
82. Zhang, X., Loijens, J.C., Boronenkov, I.V., Parker, G.J., Norris, F.A., Chen, J., Thum, O., Prestwich, G.D., Majerus, P.W., Anderson, R.A. 1997. Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. J. Biol. Chem. 272:17756-17761
83. Doughman, R.L., Firestone, A.J., Wojtasiak, M.L., Bunce, M.W., Anderson, R,A. 2003. Membrane ruffling requires coordination between type I phosphatidylinositol phosphate kinase and Rac signaling. J. Biol. Chem. 278:M211397200