Inhibition of phosphatidylinositol-4-phosphate 5-kinase Iα impairs localized actin remodeling and suppresses phagocytosis

Journal of Biological Chemistry

Volumn 277, Issue 46, 2002, Pages 43849-43857

  Coppolino, Marc G ^d   Dierckman, Renee ^a   Loijens, Joost ^a   Collins, Richard F ^d   Pouladi, Mahmoud ^d   Jongstra Bilen, Jenny ^d   Schreiber, Alan D ^b   Trimble, William S ^d   Anderson, Richard ^a   Grinstein, Sergio ^c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; ENZYMES; FLUORESCENCE; MUTAGENS; PLASMA APPLICATIONS; PROTEINS;

PHAGOCYTOSIS;

POLYMERIZATION;

ACTIN; F ACTIN; FC RECEPTOR; GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE 5 KINASE IALPHA; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

ACTINS; ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; DNA; ESCHERICHIA COLI; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GREEN FLUORESCENT PROTEINS; IMMUNOGLOBULIN G; LUMINESCENT PROTEINS; MACROPHAGES; MICE; MICROSCOPY, FLUORESCENCE; MUTATION; PHAGOCYTOSIS; PHAGOSOMES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN ISOFORMS; TIME FACTORS; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0346461844     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209046200     Document Type: Article

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