Higher-Order Looping and Nuclear Organization of Tcra Facilitate Targeted RAG Cleavage and Regulated Rearrangement in Recombination Centers

Cell Reports

Volumn 3, Issue 2, 2013, Pages 359-370

  Chaumeil, Julie ^a   Micsinai, Mariann ^a,b   Ntziachristos, Panagiotis ^a   Deriano, Ludovic ^a,f   Wang, Joy M H ^a,g   Ji, Yanhong ^c   Nora, Elphege P ^d   Rodesch, Matthew J ^e   Jeddeloh, Jeffrey A ^e   Aifantis, Iannis ^a   Kluger, Yuval ^b   Schatz, David G ^c   Skok, Jane A ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INSTITUT CURIE   (France)

^e Roche NimbleGen Inc   (United States)

^f INSTITUT PASTEUR   (France)

^g MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN RAG; RECOMBINASE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL NUCLEUS; CELL STRUCTURE; CHROMATIN; CONTROLLED STUDY; GENE; GENE LOCUS; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETIC REGULATION; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; TCRA GENE;

ALLELES; ANIMALS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE PROTEINS; CELL NUCLEUS; DNA DAMAGE; DNA-BINDING PROTEINS; GENETIC LOCI; GENOMIC INSTABILITY; HISTONES; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; TUMOR SUPPRESSOR PROTEINS; V(D)J RECOMBINATION;

EID: 84874283254     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.01.024     Document Type: Article

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