Phosphorylation of NuMA by Aurora-A kinase in PC-3 prostate cancer cells affects proliferation, survival, and interphase NuMA localization

Journal of Cellular Biochemistry

Volumn 114, Issue 4, 2013, Pages 823-830

  Toughiri, Raheleh ^a   Li, Xiang ^a   Du, Quansheng ^b   Bieberich, Charles J ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

APOPTOSIS; Aurora A; CANCER THERAPY; CELL PROLIFERATION; NuMA; PROSTATE CANCER

Indexed keywords

AURORA A KINASE; NUCLEAR MITOTIC APPARATUS PROTEIN; NUCLEAR PROTEIN; SMALL MOLECULE AURORA A INHIBITOR; SMALL MOLECULE TRANSPORT AGENT; TOZASERTIB; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GRADING; CANCER PROGNOSIS; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SEPARATION; CELL SURVIVAL; CENTROSOME; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERPHASE; MALE; MITOSIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEOMICS; REVERSE IN GEL KINASE ASSAY; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ALANINE; AMINO ACID SUBSTITUTION; ANTIGENS, NUCLEAR; APOPTOSIS; AURORA KINASES; BINDING SITES; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; INTERPHASE; MALE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR MATRIX-ASSOCIATED PROTEINS; PHOSPHORYLATION; PIPERAZINES; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; TIME FACTORS; TRANSFECTION;

EID: 84874272587     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24421     Document Type: Article

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