-
1
-
-
79960145997
-
Receptor oligomerization: A pivotal mechanism for regulating chemokine function
-
L.M. Munoz, P. Lucas, B.L. Holgado, R. Barroso, B. Vega, and J.M. Rodriguez-Frade Receptor oligomerization: a pivotal mechanism for regulating chemokine function Pharmacol Ther 131 2011 351 358
-
(2011)
Pharmacol Ther
, vol.131
, pp. 351-358
-
-
Munoz, L.M.1
Lucas, P.2
Holgado, B.L.3
Barroso, R.4
Vega, B.5
Rodriguez-Frade, J.M.6
-
2
-
-
79952105330
-
Chemokine oligomerization and interactions with receptors and glycosaminoglycans: The role of structural dynamics in function
-
C.L. Salanga, and T.M. Handel Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in function Exp Cell Res 317 2011 590 601
-
(2011)
Exp Cell Res
, vol.317
, pp. 590-601
-
-
Salanga, C.L.1
Handel, T.M.2
-
3
-
-
84862162672
-
Chemokine receptor oligomerization: A further step toward chemokine function
-
L.M. Munoz, B.L. Holgado, A.C. Martinez, J.M. Rodriguez-Frade, and M. Mellado Chemokine receptor oligomerization: a further step toward chemokine function Immunol Lett 145 2012 23 29
-
(2012)
Immunol Lett
, vol.145
, pp. 23-29
-
-
Munoz, L.M.1
Holgado, B.L.2
Martinez, A.C.3
Rodriguez-Frade, J.M.4
Mellado, M.5
-
4
-
-
81555213635
-
Pharmacological modulation of chemokine receptor function
-
D.J. Scholten, M. Canals, D. Maussang, L. Roumen, M.J. Smit, and M. Wijtmans Pharmacological modulation of chemokine receptor function Br J Pharmacol 165 2012 1617 1643
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1617-1643
-
-
Scholten, D.J.1
Canals, M.2
Maussang, D.3
Roumen, L.4
Smit, M.J.5
Wijtmans, M.6
-
5
-
-
60749125231
-
D6 and the atypical chemokine receptor family: Novel regulators of immune and inflammatory processes
-
G.J. Graham D6 and the atypical chemokine receptor family: novel regulators of immune and inflammatory processes Eur J Immunol 39 2009 342 351
-
(2009)
Eur J Immunol
, vol.39
, pp. 342-351
-
-
Graham, G.J.1
-
6
-
-
84862182338
-
The biochemistry and biology of the atypical chemokine receptors
-
G.J. Graham, M. Locati, A. Mantovani, A. Rot, and M. Thelen The biochemistry and biology of the atypical chemokine receptors Immunol Lett 145 2012 30 38
-
(2012)
Immunol Lett
, vol.145
, pp. 30-38
-
-
Graham, G.J.1
Locati, M.2
Mantovani, A.3
Rot, A.4
Thelen, M.5
-
7
-
-
66049128598
-
AMD3100 is a CXCR7 ligand with allosteric agonist properties
-
I. Kalatskaya, Y.A. Berchiche, S. Gravel, B.J. Limberg, J.S. Rosenbaum, and N. Heveker AMD3100 is a CXCR7 ligand with allosteric agonist properties Mol Pharmacol 75 2009 1240 1247
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1240-1247
-
-
Kalatskaya, I.1
Berchiche, Y.A.2
Gravel, S.3
Limberg, B.J.4
Rosenbaum, J.S.5
Heveker, N.6
-
8
-
-
79958269508
-
The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells
-
B.A. Zabel, S. Lewen, R.D. Berahovich, J.C. Jaen, and T.J. Schall The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells Mol Cancer 10 2011 73
-
(2011)
Mol Cancer
, vol.10
, pp. 73
-
-
Zabel, B.A.1
Lewen, S.2
Berahovich, R.D.3
Jaen, J.C.4
Schall, T.J.5
-
9
-
-
84856227953
-
The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells
-
V. Odemis, J. Lipfert, R. Kraft, P. Hajek, G. Abraham, and K. Hattermann The presumed atypical chemokine receptor CXCR7 signals through G(i/o) proteins in primary rodent astrocytes and human glioma cells Glia 60 2012 372 381
-
(2012)
Glia
, vol.60
, pp. 372-381
-
-
Odemis, V.1
Lipfert, J.2
Kraft, R.3
Hajek, P.4
Abraham, G.5
Hattermann, K.6
-
10
-
-
79955476625
-
Overcoming hurdles in developing successful drugs targeting chemokine receptors
-
T.J. Schall, and A.E. Proudfoot Overcoming hurdles in developing successful drugs targeting chemokine receptors Nat Rev Immunol 11 2011 355 363
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 355-363
-
-
Schall, T.J.1
Proudfoot, A.E.2
-
11
-
-
0032696339
-
Chemokines and asthma: Redundancy of function or a coordinated effort?
-
N.W. Lukacs, S.H. Oliveira, and C.M. Hogaboam Chemokines and asthma: redundancy of function or a coordinated effort? J Clin Invest 104 1999 995 999
-
(1999)
J Clin Invest
, vol.104
, pp. 995-999
-
-
Lukacs, N.W.1
Oliveira, S.H.2
Hogaboam, C.M.3
-
12
-
-
0033152142
-
The chemokine system: Redundancy for robust outputs
-
A. Mantovani The chemokine system: redundancy for robust outputs Immunol Today 20 1999 254 257
-
(1999)
Immunol Today
, vol.20
, pp. 254-257
-
-
Mantovani, A.1
-
14
-
-
0033036946
-
Multiple chemotactic factors: Fine control or redundancy?
-
M.N. Devalaraja, and A. Richmond Multiple chemotactic factors: fine control or redundancy? Trends Pharmacol Sci 20 1999 151 156
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 151-156
-
-
Devalaraja, M.N.1
Richmond, A.2
-
16
-
-
84856859387
-
Secreted CXCL12 (SDF-1) forms dimers under physiological conditions
-
P. Ray, S.A. Lewin, L.A. Mihalko, S.C. Lesher-Perez, S. Takayama, and K.E. Luker Secreted CXCL12 (SDF-1) forms dimers under physiological conditions Biochem J 442 2012 433 442
-
(2012)
Biochem J
, vol.442
, pp. 433-442
-
-
Ray, P.1
Lewin, S.A.2
Mihalko, L.A.3
Lesher-Perez, S.C.4
Takayama, S.5
Luker, K.E.6
-
17
-
-
78649694743
-
Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme
-
M. Ren, Q. Guo, L. Guo, M. Lenz, F. Qian, and R.R. Koenen Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme EMBO J 29 2010 3952 3966
-
(2010)
EMBO J
, vol.29
, pp. 3952-3966
-
-
Ren, M.1
Guo, Q.2
Guo, L.3
Lenz, M.4
Qian, F.5
Koenen, R.R.6
-
18
-
-
80051492024
-
Oligomeric structure of the chemokine CCL5/RANTES from NMR, MS, and SAXS data
-
X. Wang, C. Watson, J.S. Sharp, T.M. Handel, and J.H. Prestegard Oligomeric structure of the chemokine CCL5/RANTES from NMR, MS, and SAXS data Structure 19 2011 1138 1148
-
(2011)
Structure
, vol.19
, pp. 1138-1148
-
-
Wang, X.1
Watson, C.2
Sharp, J.S.3
Handel, T.M.4
Prestegard, J.H.5
-
19
-
-
0030810177
-
Glycosaminoglycans mediate cell surface oligomerization of chemokines
-
A.J. Hoogewerf, G.S. Kuschert, A.E. Proudfoot, F. Borlat, I. Clark-Lewis, and C.A. Power Glycosaminoglycans mediate cell surface oligomerization of chemokines Biochemistry 36 1997 13570 13578
-
(1997)
Biochemistry
, vol.36
, pp. 13570-13578
-
-
Hoogewerf, A.J.1
Kuschert, G.S.2
Proudfoot, A.E.3
Borlat, F.4
Clark-Lewis, I.5
Power, C.A.6
-
20
-
-
2542498611
-
Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: Implications for structure and function in vivo
-
E.K. Lau, C.D. Paavola, Z. Johnson, J.P. Gaudry, E. Geretti, and F. Borlat Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo J Biol Chem 279 2004 22294 22305
-
(2004)
J Biol Chem
, vol.279
, pp. 22294-22305
-
-
Lau, E.K.1
Paavola, C.D.2
Johnson, Z.3
Gaudry, J.P.4
Geretti, E.5
Borlat, F.6
-
21
-
-
79961040308
-
Technical advance: Surface plasmon resonance-based analysis of CXCL12 binding using immobilized lentiviral particles
-
B. Vega, L.M. Munoz, B.L. Holgado, P. Lucas, J.M. Rodriguez-Frade, and A. Calle Technical advance: surface plasmon resonance-based analysis of CXCL12 binding using immobilized lentiviral particles J Leukoc Biol 90 2011 399 408
-
(2011)
J Leukoc Biol
, vol.90
, pp. 399-408
-
-
Vega, B.1
Munoz, L.M.2
Holgado, B.L.3
Lucas, P.4
Rodriguez-Frade, J.M.5
Calle, A.6
-
22
-
-
24944451114
-
Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses
-
L. Wang, M. Fuster, P. Sriramarao, and J.D. Esko Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses Nat Immunol 6 2005 902 910
-
(2005)
Nat Immunol
, vol.6
, pp. 902-910
-
-
Wang, L.1
Fuster, M.2
Sriramarao, P.3
Esko, J.D.4
-
23
-
-
78650290827
-
A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis
-
X. Yin, J. Truty, R. Lawrence, S.C. Johns, R.S. Srinivasan, and T.M. Handel A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis Mol Cancer 9 2010 316
-
(2010)
Mol Cancer
, vol.9
, pp. 316
-
-
Yin, X.1
Truty, J.2
Lawrence, R.3
Johns, S.C.4
Srinivasan, R.S.5
Handel, T.M.6
-
24
-
-
0037452728
-
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines
-
A.E. Proudfoot, T.M. Handel, Z. Johnson, E.K. Lau, P. LiWang, and I. Clark-Lewis Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines Proc Natl Acad Sci USA 100 2003 1885 1890
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1885-1890
-
-
Proudfoot, A.E.1
Handel, T.M.2
Johnson, Z.3
Lau, E.K.4
Liwang, P.5
Clark-Lewis, I.6
-
25
-
-
0028280059
-
Neutrophil activation by monomeric interleukin-8
-
K. Rajarathnam, B.D. Sykes, C.M. Kay, B. Dewald, T. Geiser, and M. Baggiolini Neutrophil activation by monomeric interleukin-8 Science 264 1994 90 92
-
(1994)
Science
, vol.264
, pp. 90-92
-
-
Rajarathnam, K.1
Sykes, B.D.2
Kay, C.M.3
Dewald, B.4
Geiser, T.5
Baggiolini, M.6
-
26
-
-
0029010408
-
Structure-Activity relationships of chemokines
-
I. Clark-Lewis, K.S. Kim, K. Rajarathnam, J.H. Gong, B. Dewald, and B. Moser Structure-Activity relationships of chemokines J Leukoc Biol 57 1995 703 711
-
(1995)
J Leukoc Biol
, vol.57
, pp. 703-711
-
-
Clark-Lewis, I.1
Kim, K.S.2
Rajarathnam, K.3
Gong, J.H.4
Dewald, B.5
Moser, B.6
-
27
-
-
0029131699
-
A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer
-
Y. Zhang, and B.J. Rollins A dominant negative inhibitor indicates that monocyte chemoattractant protein 1 functions as a dimer Mol Cell Biol 15 1995 4851 4855
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4851-4855
-
-
Zhang, Y.1
Rollins, B.J.2
-
28
-
-
0030022954
-
Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist
-
A.E. Proudfoot, C.A. Power, A.J. Hoogewerf, M.O. Montjovent, F. Borlat, and R.E. Offord Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist J Biol Chem 271 1996 2599 2603
-
(1996)
J Biol Chem
, vol.271
, pp. 2599-2603
-
-
Proudfoot, A.E.1
Power, C.A.2
Hoogewerf, A.J.3
Montjovent, M.O.4
Borlat, F.5
Offord, R.E.6
-
29
-
-
0033534151
-
Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2
-
K. Jarnagin, D. Grunberger, M. Mulkins, B. Wong, S. Hemmerich, and C. Paavola Identification of surface residues of the monocyte chemotactic protein 1 that affect signaling through the receptor CCR2 Biochemistry 38 1999 16167 16177
-
(1999)
Biochemistry
, vol.38
, pp. 16167-16177
-
-
Jarnagin, K.1
Grunberger, D.2
Mulkins, M.3
Wong, B.4
Hemmerich, S.5
Paavola, C.6
-
30
-
-
0030683638
-
Solution structure and basis for functional activity of stromal cell-derived factor-1; Dissociation of CXCR4 activation from binding and inhibition of HIV-1
-
M.P. Crump, J.H. Gong, P. Loetscher, K. Rajarathnam, A. Amara, and F. Arenzana-Seisdedos Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1 EMBO J 16 1997 6996 7007
-
(1997)
EMBO J
, vol.16
, pp. 6996-7007
-
-
Crump, M.P.1
Gong, J.H.2
Loetscher, P.3
Rajarathnam, K.4
Amara, A.5
Arenzana-Seisdedos, F.6
-
31
-
-
34548472420
-
Structural and functional characterization of CC chemokine CCL14
-
K.Y. Blain, W. Kwiatkowski, Q. Zhao, D. La Fleur, C. Naik, and T.W. Chun Structural and functional characterization of CC chemokine CCL14 Biochemistry 46 2007 10008 10015
-
(2007)
Biochemistry
, vol.46
, pp. 10008-10015
-
-
Blain, K.Y.1
Kwiatkowski, W.2
Zhao, Q.3
La Fleur, D.4
Naik, C.5
Chun, T.W.6
-
32
-
-
0026195905
-
Neutrophils can generate their activator neutrophil-Activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-Activating peptide III
-
E. Brandt, J. Van Damme, and H.D. Flad Neutrophils can generate their activator neutrophil-Activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-Activating peptide III Cytokine 3 1991 311 321
-
(1991)
Cytokine
, vol.3
, pp. 311-321
-
-
Brandt, E.1
Van Damme, J.2
Flad, H.D.3
-
33
-
-
0032550337
-
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity
-
M. Mack, B. Luckow, P.J. Nelson, J. Cihak, G. Simmons, and P.R. Clapham Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity J Exp Med 187 1998 1215 1224
-
(1998)
J Exp Med
, vol.187
, pp. 1215-1224
-
-
MacK, M.1
Luckow, B.2
Nelson, P.J.3
Cihak, J.4
Simmons, G.5
Clapham, P.R.6
-
34
-
-
56649122050
-
Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide
-
H. Gaertner, F. Cerini, J.M. Escola, G. Kuenzi, A. Melotti, and R. Offord Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide Proc Natl Acad Sci USA 105 2008 17706 17711
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17706-17711
-
-
Gaertner, H.1
Cerini, F.2
Escola, J.M.3
Kuenzi, G.4
Melotti, A.5
Offord, R.6
-
35
-
-
54849434087
-
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
-
C.T. Veldkamp, C. Seibert, F.C. Peterson, N.B. De la Cruz, J.C. Haugner 3rd, and H. Basnet Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12 Sci Signal 1 2008 ra4
-
(2008)
Sci Signal
, vol.1
, pp. 4
-
-
Veldkamp, C.T.1
Seibert, C.2
Peterson, F.C.3
De La Cruz, N.B.4
Haugner III, J.C.5
Basnet, H.6
-
36
-
-
0037799237
-
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle
-
C. Blanpain, B.J. Doranz, A. Bondue, C. Govaerts, A. De Leener, and G. Vassart The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle J Biol Chem 278 2003 5179 5187
-
(2003)
J Biol Chem
, vol.278
, pp. 5179-5187
-
-
Blanpain, C.1
Doranz, B.J.2
Bondue, A.3
Govaerts, C.4
De Leener, A.5
Vassart, G.6
-
37
-
-
71749113474
-
Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4
-
Y. Kofuku, C. Yoshiura, T. Ueda, H. Terasawa, T. Hirai, and S. Tominaga Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4 J Biol Chem 284 2009 35240 35250
-
(2009)
J Biol Chem
, vol.284
, pp. 35240-35250
-
-
Kofuku, Y.1
Yoshiura, C.2
Ueda, T.3
Terasawa, H.4
Hirai, T.5
Tominaga, S.6
-
38
-
-
70350381113
-
Purification and functional reconstitution of monomeric mu-opioid receptors: Allosteric modulation of agonist binding by Gi2
-
A.J. Kuszak, S. Pitchiaya, J.P. Anand, H.I. Mosberg, N.G. Walter, and R.K. Sunahara Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2 J Biol Chem 284 2009 26732 26741
-
(2009)
J Biol Chem
, vol.284
, pp. 26732-26741
-
-
Kuszak, A.J.1
Pitchiaya, S.2
Anand, J.P.3
Mosberg, H.I.4
Walter, N.G.5
Sunahara, R.K.6
-
39
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
M.R. Whorton, M.P. Bokoch, S.G. Rasmussen, B. Huang, R.N. Zare, and B. Kobilka A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein Proc Natl Acad Sci USA 104 2007 7682 7687
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
-
40
-
-
42949164679
-
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer
-
M.R. Whorton, B. Jastrzebska, P.S. Park, D. Fotiadis, A. Engel, and K. Palczewski Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer J Biol Chem 283 2008 4387 4394
-
(2008)
J Biol Chem
, vol.283
, pp. 4387-4394
-
-
Whorton, M.R.1
Jastrzebska, B.2
Park, P.S.3
Fotiadis, D.4
Engel, A.5
Palczewski, K.6
-
41
-
-
78651390998
-
Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding
-
T.H. Bayburt, S.A. Vishnivetskiy, M.A. McLean, T. Morizumi, C.C. Huang, and J.J. Tesmer Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding J Biol Chem 286 2011 1420 1428
-
(2011)
J Biol Chem
, vol.286
, pp. 1420-1428
-
-
Bayburt, T.H.1
Vishnivetskiy, S.A.2
McLean, M.A.3
Morizumi, T.4
Huang, C.C.5
Tesmer, J.J.6
-
42
-
-
0033616765
-
The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2
-
J.M. Rodriguez-Frade, A.J. Vila-Coro, A.M. de Ana, J.P. Albar, A.C. Martinez, and M. Mellado The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2 Proc Natl Acad Sci USA 96 1999 3628 3633
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3628-3633
-
-
Rodriguez-Frade, J.M.1
Vila-Coro, A.J.2
De Ana, A.M.3
Albar, J.P.4
Martinez, A.C.5
Mellado, M.6
-
43
-
-
0033584355
-
Chemokine control of HIV-1 infection
-
M. Mellado, J.M. Rodriguez-Frade, A.J. Vila-Coro, A.M. de Ana, and A.C. Martinez Chemokine control of HIV-1 infection Nature 400 1999 723 724
-
(1999)
Nature
, vol.400
, pp. 723-724
-
-
Mellado, M.1
Rodriguez-Frade, J.M.2
Vila-Coro, A.J.3
De Ana, A.M.4
Martinez, A.C.5
-
44
-
-
17144473106
-
Chemokine receptor homo- or heterodimerization activates distinct signaling pathways
-
M. Mellado, J.M. Rodriguez-Frade, A.J. Vila-Coro, S. Fernandez, A. Martin de Ana, and D.R. Jones Chemokine receptor homo- or heterodimerization activates distinct signaling pathways EMBO J 20 2001 2497 2507
-
(2001)
EMBO J
, vol.20
, pp. 2497-2507
-
-
Mellado, M.1
Rodriguez-Frade, J.M.2
Vila-Coro, A.J.3
Fernandez, S.4
Martin De Ana, A.5
Jones, D.R.6
-
45
-
-
15444377047
-
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers
-
Y. Percherancier, Y.A. Berchiche, I. Slight, R. Volkmer-Engert, H. Tamamura, and N. Fujii Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers J Biol Chem 280 2005 9895 9903
-
(2005)
J Biol Chem
, vol.280
, pp. 9895-9903
-
-
Percherancier, Y.1
Berchiche, Y.A.2
Slight, I.3
Volkmer-Engert, R.4
Tamamura, H.5
Fujii, N.6
-
46
-
-
79951970155
-
Different effects of the different natural CC chemokine receptor 2b ligands on beta-Arrestin recruitment, Galphai signaling, and receptor internalization
-
Y.A. Berchiche, S. Gravel, M.E. Pelletier, G. St-Onge, and N. Heveker Different effects of the different natural CC chemokine receptor 2b ligands on beta-Arrestin recruitment, Galphai signaling, and receptor internalization Mol Pharmacol 79 2011 488 498
-
(2011)
Mol Pharmacol
, vol.79
, pp. 488-498
-
-
Berchiche, Y.A.1
Gravel, S.2
Pelletier, M.E.3
St-Onge, G.4
Heveker, N.5
-
47
-
-
13444274883
-
Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers
-
L. El-Asmar, J.Y. Springael, S. Ballet, E.U. Andrieu, G. Vassart, and M. Parmentier Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers Mol Pharmacol 67 2005 460 469
-
(2005)
Mol Pharmacol
, vol.67
, pp. 460-469
-
-
El-Asmar, L.1
Springael, J.Y.2
Ballet, S.3
Andrieu, E.U.4
Vassart, G.5
Parmentier, M.6
-
48
-
-
33645802812
-
Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers
-
J.Y. Springael, P.N. Le Minh, E. Urizar, S. Costagliola, G. Vassart, and M. Parmentier Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers Mol Pharmacol 69 2006 1652 1661
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1652-1661
-
-
Springael, J.Y.1
Le Minh, P.N.2
Urizar, E.3
Costagliola, S.4
Vassart, G.5
Parmentier, M.6
-
49
-
-
71449122467
-
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists
-
D. Sohy, H. Yano, P. de Nadai, E. Urizar, A. Guillabert, and J.A. Javitch Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists J Biol Chem 284 2009 31270 31279
-
(2009)
J Biol Chem
, vol.284
, pp. 31270-31279
-
-
Sohy, D.1
Yano, H.2
De Nadai, P.3
Urizar, E.4
Guillabert, A.5
Javitch, J.A.6
-
50
-
-
0030712312
-
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32
-
M. Benkirane, D.Y. Jin, R.F. Chun, R.A. Koup, and K.T. Jeang Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32 J Biol Chem 272 1997 30603 30606
-
(1997)
J Biol Chem
, vol.272
, pp. 30603-30606
-
-
Benkirane, M.1
Jin, D.Y.2
Chun, R.F.3
Koup, R.A.4
Jeang, K.T.5
-
51
-
-
0034724420
-
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization
-
A.J. Vila-Coro, M. Mellado, A. Martin de Ana, P. Lucas, G. del Real, and A.C. Martinez HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization Proc Natl Acad Sci USA 97 2000 3388 3393
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3388-3393
-
-
Vila-Coro, A.J.1
Mellado, M.2
Martin De Ana, A.3
Lucas, P.4
Del Real, G.5
Martinez, A.C.6
-
52
-
-
0344171936
-
Similarities and differences in RANTES- and (AOP)-RANTES-triggered signals: Implications for chemotaxis
-
J.M. Rodriguez-Frade, A.J. Vila-Coro, A. Martin, M. Nieto, F. Sanchez-Madrid, and A.E. Proudfoot Similarities and differences in RANTES- and (AOP)-RANTES-triggered signals: implications for chemotaxis J Cell Biol 144 1999 755 765
-
(1999)
J Cell Biol
, vol.144
, pp. 755-765
-
-
Rodriguez-Frade, J.M.1
Vila-Coro, A.J.2
Martin, A.3
Nieto, M.4
Sanchez-Madrid, F.5
Proudfoot, A.E.6
-
53
-
-
0035861556
-
Determinants of the trans-dominant negative effect of truncated forms of the CCR5 chemokine receptor
-
M. Chelli, and M. Alizon Determinants of the trans-dominant negative effect of truncated forms of the CCR5 chemokine receptor J Biol Chem 276 2001 46975 46982
-
(2001)
J Biol Chem
, vol.276
, pp. 46975-46982
-
-
Chelli, M.1
Alizon, M.2
-
54
-
-
0036178934
-
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies
-
C. Blanpain, J.M. Vanderwinden, J. Cihak, V. Wittamer, E. Le Poul, and H. Issafras Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies Mol Biol Cell 13 2002 723 737
-
(2002)
Mol Biol Cell
, vol.13
, pp. 723-737
-
-
Blanpain, C.1
Vanderwinden, J.M.2
Cihak, J.3
Wittamer, V.4
Le Poul, E.5
Issafras, H.6
-
55
-
-
0037144581
-
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors
-
H. Issafras, S. Angers, S. Bulenger, C. Blanpain, M. Parmentier, and C. Labbe-Jullie Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors J Biol Chem 277 2002 34666 34673
-
(2002)
J Biol Chem
, vol.277
, pp. 34666-34673
-
-
Issafras, H.1
Angers, S.2
Bulenger, S.3
Blanpain, C.4
Parmentier, M.5
Labbe-Jullie, C.6
-
56
-
-
48249131606
-
CXCR4-CCR5: A couple modulating T cell functions
-
R.L. Contento, B. Molon, C. Boularan, T. Pozzan, S. Manes, and S. Marullo CXCR4-CCR5: a couple modulating T cell functions Proc Natl Acad Sci USA 105 2008 10101 10106
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10101-10106
-
-
Contento, R.L.1
Molon, B.2
Boularan, C.3
Pozzan, T.4
Manes, S.5
Marullo, S.6
-
57
-
-
0037131325
-
Rescue of HIV-1 receptor function through cooperation between different forms of the CCR5 chemokine receptor
-
M. Chelli, and M. Alizon Rescue of HIV-1 receptor function through cooperation between different forms of the CCR5 chemokine receptor J Biol Chem 277 2002 39388 39396
-
(2002)
J Biol Chem
, vol.277
, pp. 39388-39396
-
-
Chelli, M.1
Alizon, M.2
-
58
-
-
10744223537
-
Identification of amino acid residues crucial for chemokine receptor dimerization
-
P. Hernanz-Falcon, J.M. Rodriguez-Frade, A. Serrano, D. Juan, A. del Sol, and S.F. Soriano Identification of amino acid residues crucial for chemokine receptor dimerization Nat Immunol 5 2004 216 223
-
(2004)
Nat Immunol
, vol.5
, pp. 216-223
-
-
Hernanz-Falcon, P.1
Rodriguez-Frade, J.M.2
Serrano, A.3
Juan, D.4
Del Sol, A.5
Soriano, S.F.6
-
59
-
-
20644437515
-
On the dimerization of CCR5
-
Author reply 535-536
-
J. Lemay, S. Marullo, R. Jockers, M. Alizon, and A. Brelot On the dimerization of CCR5 Nat Immunol 6 2005 535 Author reply 535-536
-
(2005)
Nat Immunol
, vol.6
, pp. 535
-
-
Lemay, J.1
Marullo, S.2
Jockers, R.3
Alizon, M.4
Brelot, A.5
-
60
-
-
27844541754
-
G protein-coupled receptor kinases promote phosphorylation and beta-Arrestin-mediated internalization of CCR5 homo- and hetero-oligomers
-
F. Huttenrauch, B. Pollok-Kopp, and M. Oppermann G protein-coupled receptor kinases promote phosphorylation and beta-Arrestin-mediated internalization of CCR5 homo- and hetero-oligomers J Biol Chem 280 2005 37503 37515
-
(2005)
J Biol Chem
, vol.280
, pp. 37503-37515
-
-
Huttenrauch, F.1
Pollok-Kopp, B.2
Oppermann, M.3
-
61
-
-
78049383086
-
Na +/H + exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer
-
M.M. Hammad, Y.Q. Kuang, R. Yan, H. Allen, and D.J. Dupre Na +/H + exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer J Biol Chem 285 2010 34653 34664
-
(2010)
J Biol Chem
, vol.285
, pp. 34653-34664
-
-
Hammad, M.M.1
Kuang, Y.Q.2
Yan, R.3
Allen, H.4
Dupre, D.J.5
-
62
-
-
80051475406
-
Dependence on different Rab GTPases for the trafficking of CXCR4 and CCR5 homo or heterodimers between the endoplasmic reticulum and plasma membrane in Jurkat cells
-
N. Charette, P. Holland, J. Frazer, H. Allen, and D.J. Dupre Dependence on different Rab GTPases for the trafficking of CXCR4 and CCR5 homo or heterodimers between the endoplasmic reticulum and plasma membrane in Jurkat cells Cell Signal 23 2011 1738 1749
-
(2011)
Cell Signal
, vol.23
, pp. 1738-1749
-
-
Charette, N.1
Holland, P.2
Frazer, J.3
Allen, H.4
Dupre, D.J.5
-
63
-
-
84863993382
-
Dopamine receptor-interacting protein 78 acts as a molecular chaperone for CCR5 chemokine receptor signaling complex organization
-
Y.Q. Kuang, N. Charette, J. Frazer, P.J. Holland, K.M. Attwood, and G. Dellaire Dopamine receptor-interacting protein 78 acts as a molecular chaperone for CCR5 chemokine receptor signaling complex organization PLoS One 7 2012 e40522
-
(2012)
PLoS One
, vol.7
, pp. 40522
-
-
Kuang, Y.Q.1
Charette, N.2
Frazer, J.3
Holland, P.J.4
Attwood, K.M.5
Dellaire, G.6
-
64
-
-
23344447877
-
The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities
-
S. Wilson, G. Wilkinson, and G. Milligan The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities J Biol Chem 280 2005 28663 28674
-
(2005)
J Biol Chem
, vol.280
, pp. 28663-28674
-
-
Wilson, S.1
Wilkinson, G.2
Milligan, G.3
-
65
-
-
73349084313
-
Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers
-
L. Martinez Munoz, P. Lucas, G. Navarro, A.I. Checa, R. Franco, and A.C. Martinez Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers J Immunol 183 2009 7337 7346
-
(2009)
J Immunol
, vol.183
, pp. 7337-7346
-
-
Martinez Munoz, L.1
Lucas, P.2
Navarro, G.3
Checa, A.I.4
Franco, R.5
Martinez, A.C.6
-
66
-
-
0142103411
-
Ligand-independent CXCR2 dimerization
-
F. Trettel, S. Di Bartolomeo, C. Lauro, M. Catalano, M.T. Ciotti, and C. Limatola Ligand-independent CXCR2 dimerization J Biol Chem 278 2003 40980 40988
-
(2003)
J Biol Chem
, vol.278
, pp. 40980-40988
-
-
Trettel, F.1
Di Bartolomeo, S.2
Lauro, C.3
Catalano, M.4
Ciotti, M.T.5
Limatola, C.6
-
67
-
-
19544368784
-
Cysteine residues are critical for chemokine receptor CXCR2 functional properties
-
C. Limatola, S. Di Bartolomeo, M. Catalano, F. Trettel, S. Fucile, and L. Castellani Cysteine residues are critical for chemokine receptor CXCR2 functional properties Exp Cell Res 307 2005 65 75
-
(2005)
Exp Cell Res
, vol.307
, pp. 65-75
-
-
Limatola, C.1
Di Bartolomeo, S.2
Catalano, M.3
Trettel, F.4
Fucile, S.5
Castellani, L.6
-
68
-
-
0033209897
-
The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
-
A.J. Vila-Coro, J.M. Rodriguez-Frade, A. Martin De Ana, M.C. Moreno-Ortiz, A.C. Martinez, and M. Mellado The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway FASEB J 13 1999 1699 1710
-
(1999)
FASEB J
, vol.13
, pp. 1699-1710
-
-
Vila-Coro, A.J.1
Rodriguez-Frade, J.M.2
Martin De Ana, A.3
Moreno-Ortiz, M.C.4
Martinez, A.C.5
Mellado, M.6
-
69
-
-
0037474238
-
Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor
-
G.J. Babcock, M. Farzan, and J. Sodroski Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor J Biol Chem 278 2003 3378 3385
-
(2003)
J Biol Chem
, vol.278
, pp. 3378-3385
-
-
Babcock, G.J.1
Farzan, M.2
Sodroski, J.3
-
70
-
-
44449087996
-
Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET)
-
Chapter 5, Unit 5 23
-
F.F. Hamdan, Y. Percherancier, B. Breton, and M. Bouvier Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET) Curr Protoc Neurosci 2006 Chapter 5, Unit 5 23
-
(2006)
Curr Protoc Neurosci
-
-
Hamdan, F.F.1
Percherancier, Y.2
Breton, B.3
Bouvier, M.4
-
71
-
-
47249114905
-
CXCR4 dimerization and beta-Arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome
-
B. Lagane, K.Y. Chow, K. Balabanian, A. Levoye, J. Harriague, and T. Planchenault CXCR4 dimerization and beta-Arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome Blood 112 2008 34 44
-
(2008)
Blood
, vol.112
, pp. 34-44
-
-
Lagane, B.1
Chow, K.Y.2
Balabanian, K.3
Levoye, A.4
Harriague, J.5
Planchenault, T.6
-
72
-
-
78449262856
-
Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells
-
T. Tanaka, W. Nomura, T. Narumi, A. Masuda, and H. Tamamura Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells J Am Chem Soc 132 2010 15899 15901
-
(2010)
J Am Chem Soc
, vol.132
, pp. 15899-15901
-
-
Tanaka, T.1
Nomura, W.2
Narumi, T.3
Masuda, A.4
Tamamura, H.5
-
73
-
-
84866065396
-
A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry
-
W.T. Choi, S. Kumar, N. Madani, X. Han, S. Tian, and C.Z. Dong A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry Biochemistry 51 2012 7078 7086
-
(2012)
Biochemistry
, vol.51
, pp. 7078-7086
-
-
Choi, W.T.1
Kumar, S.2
Madani, N.3
Han, X.4
Tian, S.5
Dong, C.Z.6
-
74
-
-
3042690324
-
Regulation of CXCR4 receptor dimerization by the chemokine SDF-1alpha and the HIV-1 coat protein gp120: A fluorescence resonance energy transfer (FRET) study
-
P.T. Toth, D. Ren, and R.J. Miller Regulation of CXCR4 receptor dimerization by the chemokine SDF-1alpha and the HIV-1 coat protein gp120: a fluorescence resonance energy transfer (FRET) study J Pharmacol Exp Ther 310 2004 8 17
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 8-17
-
-
Toth, P.T.1
Ren, D.2
Miller, R.J.3
-
75
-
-
33750447940
-
Dimerization of CXCR4 in living malignant cells: Control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions
-
J. Wang, L. He, C.A. Combs, G. Roderiquez, and M.A. Norcross Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions Mol Cancer Ther 5 2006 2474 2483
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2474-2483
-
-
Wang, J.1
He, L.2
Combs, C.A.3
Roderiquez, G.4
Norcross, M.A.5
-
76
-
-
58149299308
-
Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis
-
M. Hamatake, T. Aoki, Y. Futahashi, E. Urano, N. Yamamoto, and J. Komano Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis Cancer Sci 100 2009 95 102
-
(2009)
Cancer Sci
, vol.100
, pp. 95-102
-
-
Hamatake, M.1
Aoki, T.2
Futahashi, Y.3
Urano, E.4
Yamamoto, N.5
Komano, J.6
-
77
-
-
61449217021
-
Imaging chemokine receptor dimerization with firefly luciferase complementation
-
K.E. Luker, M. Gupta, and G.D. Luker Imaging chemokine receptor dimerization with firefly luciferase complementation FASEB J 23 2009 823 834
-
(2009)
FASEB J
, vol.23
, pp. 823-834
-
-
Luker, K.E.1
Gupta, M.2
Luker, G.D.3
-
78
-
-
67650349084
-
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
-
A. Levoye, K. Balabanian, F. Baleux, F. Bachelerie, and B. Lagane CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling Blood 113 2009 6085 6093
-
(2009)
Blood
, vol.113
, pp. 6085-6093
-
-
Levoye, A.1
Balabanian, K.2
Baleux, F.3
Bachelerie, F.4
Lagane, B.5
-
79
-
-
78149461804
-
Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes
-
M.A. Zhukovsky, S. Basmaciogullari, B. Pacheco, L. Wang, N. Madani, and H. Haim Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes PLoS One 5 2010 e13249
-
(2010)
PLoS One
, vol.5
, pp. 13249
-
-
Zhukovsky, M.A.1
Basmaciogullari, S.2
Pacheco, B.3
Wang, L.4
Madani, N.5
Haim, H.6
-
80
-
-
85027927015
-
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
-
B. Wu, E.Y. Chien, C.D. Mol, G. Fenalti, W. Liu, and V. Katritch Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science 330 2010 1066 1071
-
(2010)
Science
, vol.330
, pp. 1066-1071
-
-
Wu, B.1
Chien, E.Y.2
Mol, C.D.3
Fenalti, G.4
Liu, W.5
Katritch, V.6
-
81
-
-
84863780022
-
Characterization of the homodimerization interface and functional hotspots of the CXCR4 chemokine receptor
-
D. Rodriguez, and H. Gutierrez-de-Teran Characterization of the homodimerization interface and functional hotspots of the CXCR4 chemokine receptor Proteins 80 2012 1919 1928
-
(2012)
Proteins
, vol.80
, pp. 1919-1928
-
-
Rodriguez, D.1
Gutierrez-De-Teran, H.2
-
82
-
-
84865140619
-
Regulation of cell migration by sphingomyelin synthases: Sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway
-
S. Asano, K. Kitatani, M. Taniguchi, M. Hashimoto, K. Zama, and S. Mitsutake Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway Mol Cell Biol 32 2012 3242 3252
-
(2012)
Mol Cell Biol
, vol.32
, pp. 3242-3252
-
-
Asano, S.1
Kitatani, K.2
Taniguchi, M.3
Hashimoto, M.4
Zama, K.5
Mitsutake, S.6
-
83
-
-
42449130587
-
The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization
-
A. Chakera, R.M. Seeber, A.E. John, K.A. Eidne, and D.R. Greaves The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization Mol Pharmacol 73 2008 1362 1370
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1362-1370
-
-
Chakera, A.1
Seeber, R.M.2
John, A.E.3
Eidne, K.A.4
Greaves, D.R.5
-
84
-
-
0035664761
-
Lipid-facing correlated mutations and dimerization in G-protein coupled receptors
-
P.R. Gouldson, M.K. Dean, C.R. Snell, R.P. Bywater, G. Gkoutos, and C.A. Reynolds Lipid-facing correlated mutations and dimerization in G-protein coupled receptors Protein Eng 14 2001 759 767
-
(2001)
Protein Eng
, vol.14
, pp. 759-767
-
-
Gouldson, P.R.1
Dean, M.K.2
Snell, C.R.3
Bywater, R.P.4
Gkoutos, G.5
Reynolds, C.A.6
-
85
-
-
0842285404
-
Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor
-
J.M. Rodriguez-Frade, G. del Real, A. Serrano, P. Hernanz-Falcon, S.F. Soriano, and A.J. Vila-Coro Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor EMBO J 23 2004 66 76
-
(2004)
EMBO J
, vol.23
, pp. 66-76
-
-
Rodriguez-Frade, J.M.1
Del Real, G.2
Serrano, A.3
Hernanz-Falcon, P.4
Soriano, S.F.5
Vila-Coro, A.J.6
-
86
-
-
34447105555
-
Gene conversion between mammalian CCR2 and CCR5 chemokine receptor genes: A potential mechanism for receptor dimerization
-
N. Vazquez-Salat, N. Yuhki, T. Beck, S.J. O'Brien, and W.J. Murphy Gene conversion between mammalian CCR2 and CCR5 chemokine receptor genes: a potential mechanism for receptor dimerization Genomics 90 2007 213 224
-
(2007)
Genomics
, vol.90
, pp. 213-224
-
-
Vazquez-Salat, N.1
Yuhki, N.2
Beck, T.3
O'Brien, S.J.4
Murphy, W.J.5
-
87
-
-
79951713324
-
Application of G protein-coupled receptor-heteromer identification technology to monitor beta-Arrestin recruitment to G protein-coupled receptor heteromers
-
H.B. See, R.M. Seeber, M. Kocan, K.A. Eidne, and K.D. Pfleger Application of G protein-coupled receptor-heteromer identification technology to monitor beta-Arrestin recruitment to G protein-coupled receptor heteromers Assay Drug Dev Technol 9 2011 21 30
-
(2011)
Assay Drug Dev Technol
, vol.9
, pp. 21-30
-
-
See, H.B.1
Seeber, R.M.2
Kocan, M.3
Eidne, K.A.4
Pfleger, K.D.5
-
88
-
-
35648971157
-
Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers
-
D. Sohy, M. Parmentier, and J.Y. Springael Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers J Biol Chem 282 2007 30062 30069
-
(2007)
J Biol Chem
, vol.282
, pp. 30062-30069
-
-
Sohy, D.1
Parmentier, M.2
Springael, J.Y.3
-
89
-
-
54849415924
-
Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors
-
N. Isik, D. Hereld, and T. Jin Fluorescence resonance energy transfer imaging reveals that chemokine-binding modulates heterodimers of CXCR4 and CCR5 receptors PLoS One 3 2008 e3424
-
(2008)
PLoS One
, vol.3
, pp. 3424
-
-
Isik, N.1
Hereld, D.2
Jin, T.3
-
90
-
-
21744444159
-
Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4
-
J. Wang, R. Alvarez, G. Roderiquez, E. Guan, and M.A. Norcross Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4 J Cell Biochem 93 2004 753 760
-
(2004)
J Cell Biochem
, vol.93
, pp. 753-760
-
-
Wang, J.1
Alvarez, R.2
Roderiquez, G.3
Guan, E.4
Norcross, M.A.5
-
91
-
-
35548996783
-
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
-
F. Sierro, C. Biben, L. Martinez-Munoz, M. Mellado, R.M. Ransohoff, and M. Li Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 Proc Natl Acad Sci USA 104 2007 14759 14764
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14759-14764
-
-
Sierro, F.1
Biben, C.2
Martinez-Munoz, L.3
Mellado, M.4
Ransohoff, R.M.5
Li, M.6
-
92
-
-
80052768977
-
CXCR7/CXCR4 heterodimer constitutively recruits beta-Arrestin to enhance cell migration
-
F.M. Decaillot, M.A. Kazmi, Y. Lin, S. Ray-Saha, T.P. Sakmar, and P. Sachdev CXCR7/CXCR4 heterodimer constitutively recruits beta-Arrestin to enhance cell migration J Biol Chem 286 2011 32188 32197
-
(2011)
J Biol Chem
, vol.286
, pp. 32188-32197
-
-
Decaillot, F.M.1
Kazmi, M.A.2
Lin, Y.3
Ray-Saha, S.4
Sakmar, T.P.5
Sachdev, P.6
-
93
-
-
84859768529
-
Identification and profiling of novel alpha1A-Adrenoceptor-CXC chemokine receptor 2 heteromer
-
S. Mustafa, H.B. See, R.M. Seeber, S.P. Armstrong, C.W. White, and S. Ventura Identification and profiling of novel alpha1A-Adrenoceptor-CXC chemokine receptor 2 heteromer J Biol Chem 287 2012 12952 12965
-
(2012)
J Biol Chem
, vol.287
, pp. 12952-12965
-
-
Mustafa, S.1
See, H.B.2
Seeber, R.M.3
Armstrong, S.P.4
White, C.W.5
Ventura, S.6
-
94
-
-
0036430682
-
Interactions of opioid and chemokine receptors: Oligomerization of mu, kappa, and delta with CCR5 on immune cells
-
S. Suzuki, L.F. Chuang, P. Yau, R.H. Doi, and R.Y. Chuang Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells Exp Cell Res 280 2002 192 200
-
(2002)
Exp Cell Res
, vol.280
, pp. 192-200
-
-
Suzuki, S.1
Chuang, L.F.2
Yau, P.3
Doi, R.H.4
Chuang, R.Y.5
-
95
-
-
0346056873
-
Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor
-
C. Chen, J. Li, G. Bot, I. Szabo, T.J. Rogers, and L.Y. Liu-Chen Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor Eur J Pharmacol 483 2004 175 186
-
(2004)
Eur J Pharmacol
, vol.483
, pp. 175-186
-
-
Chen, C.1
Li, J.2
Bot, G.3
Szabo, I.4
Rogers, T.J.5
Liu-Chen, L.Y.6
-
96
-
-
84863362554
-
Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5
-
Y. Yuan, C.K. Arnatt, G. Li, K.M. Haney, D. Ding, and J.C. Jacob Design and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5 Org Biomol Chem 10 2012 2633 2646
-
(2012)
Org Biomol Chem
, vol.10
, pp. 2633-2646
-
-
Yuan, Y.1
Arnatt, C.K.2
Li, G.3
Haney, K.M.4
Ding, D.5
Jacob, J.C.6
-
97
-
-
47249090414
-
Chemokine CXCL8 modulates GluR1 phosphorylation
-
M. Catalano, F. Trettel, R. Cipriani, C. Lauro, F. Sobrero, and F. Eusebi Chemokine CXCL8 modulates GluR1 phosphorylation J Neuroimmunol 198 2008 75 81
-
(2008)
J Neuroimmunol
, vol.198
, pp. 75-81
-
-
Catalano, M.1
Trettel, F.2
Cipriani, R.3
Lauro, C.4
Sobrero, F.5
Eusebi, F.6
-
98
-
-
44449175613
-
CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2-DOP receptor heterodimer
-
G. Parenty, S. Appelbe, and G. Milligan CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2-DOP receptor heterodimer Biochem J 412 2008 245 256
-
(2008)
Biochem J
, vol.412
, pp. 245-256
-
-
Parenty, G.1
Appelbe, S.2
Milligan, G.3
-
99
-
-
42249106416
-
Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation
-
O.M. Pello, L. Martinez-Munoz, V. Parrillas, A. Serrano, J.M. Rodriguez-Frade, and M.J. Toro Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation Eur J Immunol 38 2008 537 549
-
(2008)
Eur J Immunol
, vol.38
, pp. 537-549
-
-
Pello, O.M.1
Martinez-Munoz, L.2
Parrillas, V.3
Serrano, A.4
Rodriguez-Frade, J.M.5
Toro, M.J.6
-
101
-
-
77956553602
-
The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Galphai proteins, and constitutively impairs CXCR4 functioning
-
S. Nijmeijer, R. Leurs, M.J. Smit, and H.F. Vischer The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Galphai proteins, and constitutively impairs CXCR4 functioning J Biol Chem 285 2010 29632 29641
-
(2010)
J Biol Chem
, vol.285
, pp. 29632-29641
-
-
Nijmeijer, S.1
Leurs, R.2
Smit, M.J.3
Vischer, H.F.4
-
102
-
-
84870322831
-
EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5
-
R. Barroso, L. Martinez Munoz, S. Barrondo, B. Vega, B.L. Holgado, and P. Lucas EBI2 regulates CXCL13-mediated responses by heterodimerization with CXCR5 FASEB J 26 2012 4841 4854
-
(2012)
FASEB J
, vol.26
, pp. 4841-4854
-
-
Barroso, R.1
Martinez Munoz, L.2
Barrondo, S.3
Vega, B.4
Holgado, B.L.5
Lucas, P.6
-
103
-
-
33747150625
-
CXCR4 physically associates with the T cell receptor to signal in T cells
-
A. Kumar, T.D. Humphreys, K.N. Kremer, P.S. Bramati, L. Bradfield, and C.E. Edgar CXCR4 physically associates with the T cell receptor to signal in T cells Immunity 25 2006 213 224
-
(2006)
Immunity
, vol.25
, pp. 213-224
-
-
Kumar, A.1
Humphreys, T.D.2
Kremer, K.N.3
Bramati, P.S.4
Bradfield, L.5
Edgar, C.E.6
-
104
-
-
13044317266
-
Constitutive cell surface association between CD4 and CCR5
-
X. Xiao, L. Wu, T.S. Stantchev, Y.R. Feng, S. Ugolini, and H. Chen Constitutive cell surface association between CD4 and CCR5 Proc Natl Acad Sci USA 96 1999 7496 7501
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7496-7501
-
-
Xiao, X.1
Wu, L.2
Stantchev, T.S.3
Feng, Y.R.4
Ugolini, S.5
Chen, H.6
-
105
-
-
0035082676
-
CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells
-
I.I. Singer, S. Scott, D.W. Kawka, J. Chin, B.L. Daugherty, and J.A. DeMartino CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells J Virol 75 2001 3779 3790
-
(2001)
J Virol
, vol.75
, pp. 3779-3790
-
-
Singer, I.I.1
Scott, S.2
Kawka, D.W.3
Chin, J.4
Daugherty, B.L.5
Demartino, J.A.6
-
106
-
-
79251591614
-
A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors
-
E. Doumazane, P. Scholler, J.M. Zwier, E. Trinquet, P. Rondard, and J.P. Pin A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors FASEB J 25 2011 66 77
-
(2011)
FASEB J
, vol.25
, pp. 66-77
-
-
Doumazane, E.1
Scholler, P.2
Zwier, J.M.3
Trinquet, E.4
Rondard, P.5
Pin, J.P.6
-
107
-
-
79954516650
-
G protein-coupled receptors: Walking hand-in-hand, talking hand-in-hand?
-
H.F. Vischer, A.O. Watts, S. Nijmeijer, and R. Leurs G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand? Br J Pharmacol 163 2011 246 260
-
(2011)
Br J Pharmacol
, vol.163
, pp. 246-260
-
-
Vischer, H.F.1
Watts, A.O.2
Nijmeijer, S.3
Leurs, R.4
-
108
-
-
84873936242
-
Novel approach to quantify GPCR dimerization equilibrium using bioluminescence resonance energy transfer
-
In press
-
I. Kufareva, B. Stephens, C.T. Gilliland, B. Wu, G. Fenalti, and D. Hamel Novel approach to quantify GPCR dimerization equilibrium using bioluminescence resonance energy transfer Methods Mol Biol 2012 In press
-
(2012)
Methods Mol Biol
-
-
Kufareva, I.1
Stephens, B.2
Gilliland, C.T.3
Wu, B.4
Fenalti, G.5
Hamel, D.6
-
109
-
-
77249150932
-
Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules
-
J.A. Hern, A.H. Baig, G.I. Mashanov, B. Birdsall, J.E. Corrie, and S. Lazareno Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules Proc Natl Acad Sci USA 107 2010 2693 2698
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2693-2698
-
-
Hern, J.A.1
Baig, A.H.2
Mashanov, G.I.3
Birdsall, B.4
Corrie, J.E.5
Lazareno, S.6
-
110
-
-
69249206623
-
G protein-coupled receptor hetero-dimerization: Contribution to pharmacology and function
-
G. Milligan G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function Br J Pharmacol 158 2009 5 14
-
(2009)
Br J Pharmacol
, vol.158
, pp. 5-14
-
-
Milligan, G.1
-
111
-
-
0005169503
-
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2
-
K.A. Jones, B. Borowsky, J.A. Tamm, D.A. Craig, M.M. Durkin, and M. Dai GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2 Nature 396 1998 674 679
-
(1998)
Nature
, vol.396
, pp. 674-679
-
-
Jones, K.A.1
Borowsky, B.2
Tamm, J.A.3
Craig, D.A.4
Durkin, M.M.5
Dai, M.6
-
112
-
-
17444380779
-
Heterodimerization is required for the formation of a functional GABA(B) receptor
-
J.H. White, A. Wise, M.J. Main, A. Green, N.J. Fraser, and G.H. Disney Heterodimerization is required for the formation of a functional GABA(B) receptor Nature 396 1998 679 682
-
(1998)
Nature
, vol.396
, pp. 679-682
-
-
White, J.H.1
Wise, A.2
Main, M.J.3
Green, A.4
Fraser, N.J.5
Disney, G.H.6
-
113
-
-
80055081893
-
Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
-
L.J. Drury, J.J. Ziarek, S. Gravel, C.T. Veldkamp, T. Takekoshi, and S.T. Hwang Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways Proc Natl Acad Sci USA 108 2011 17655 17660
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17655-17660
-
-
Drury, L.J.1
Ziarek, J.J.2
Gravel, S.3
Veldkamp, C.T.4
Takekoshi, T.5
Hwang, S.T.6
-
114
-
-
25844464220
-
The specificity and molecular basis of alpha1-Adrenoceptor and CXCR chemokine receptor dimerization
-
G. Milligan, S. Wilson, and J.F. Lopez-Gimenez The specificity and molecular basis of alpha1-Adrenoceptor and CXCR chemokine receptor dimerization J Mol Neurosci 26 2005 161 168
-
(2005)
J Mol Neurosci
, vol.26
, pp. 161-168
-
-
Milligan, G.1
Wilson, S.2
Lopez-Gimenez, J.F.3
-
115
-
-
0033521097
-
Inhibition of G-protein-coupled receptor function by disruption of transmembrane domain interactions
-
N.I. Tarasova, W.G. Rice, and C.J. Michejda Inhibition of G-protein-coupled receptor function by disruption of transmembrane domain interactions J Biol Chem 274 1999 34911 34915
-
(1999)
J Biol Chem
, vol.274
, pp. 34911-34915
-
-
Tarasova, N.I.1
Rice, W.G.2
Michejda, C.J.3
-
116
-
-
62949087122
-
The apparent cooperativity of some GPCRs does not necessarily imply dimerization
-
M. Chabre, P. Deterre, and B. Antonny The apparent cooperativity of some GPCRs does not necessarily imply dimerization Trends Pharmacol Sci 30 2009 182 187
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 182-187
-
-
Chabre, M.1
Deterre, P.2
Antonny, B.3
-
117
-
-
77958152523
-
Class A GPCR heterodimers: Evidence from binding studies
-
N.J. Birdsall Class A GPCR heterodimers: evidence from binding studies Trends Pharmacol Sci 31 2010 499 508
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 499-508
-
-
Birdsall, N.J.1
-
118
-
-
18244389686
-
T cell costimulation by chemokine receptors
-
B. Molon, G. Gri, M. Bettella, C. Gomez-Mouton, A. Lanzavecchia, and A.C. Martinez T cell costimulation by chemokine receptors Nat Immunol 6 2005 465 471
-
(2005)
Nat Immunol
, vol.6
, pp. 465-471
-
-
Molon, B.1
Gri, G.2
Bettella, M.3
Gomez-Mouton, C.4
Lanzavecchia, A.5
Martinez, A.C.6
-
120
-
-
70349234110
-
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands
-
B.A. Zabel, Y. Wang, S. Lewen, R.D. Berahovich, M.E. Penfold, and P. Zhang Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands J Immunol 183 2009 3204 3211
-
(2009)
J Immunol
, vol.183
, pp. 3204-3211
-
-
Zabel, B.A.1
Wang, Y.2
Lewen, S.3
Berahovich, R.D.4
Penfold, M.E.5
Zhang, P.6
-
121
-
-
84869087515
-
Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells
-
K.E. Luker, S.A. Lewin, L.A. Mihalko, B.T. Schmidt, J.S. Winkler, and N.L. Coggins Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells Oncogene 45 2012 4750 4758
-
(2012)
Oncogene
, vol.45
, pp. 4750-4758
-
-
Luker, K.E.1
Lewin, S.A.2
Mihalko, L.A.3
Schmidt, B.T.4
Winkler, J.S.5
Coggins, N.L.6
-
122
-
-
65549152874
-
Pharmacological and biochemical characterization of human cytomegalovirus-encoded G protein-coupled receptors
-
D. Maussang, H.F. Vischer, A. Schreiber, D. Michel, and M.J. Smit Pharmacological and biochemical characterization of human cytomegalovirus- encoded G protein-coupled receptors Methods Enzymol 460 2009 151 171
-
(2009)
Methods Enzymol
, vol.460
, pp. 151-171
-
-
Maussang, D.1
Vischer, H.F.2
Schreiber, A.3
Michel, D.4
Smit, M.J.5
-
123
-
-
78651349761
-
Herpesvirus-encoded GPCRs rewire cellular signaling
-
E. Slinger, E. Langemeijer, M. Siderius, H.F. Vischer, and M.J. Smit Herpesvirus-encoded GPCRs rewire cellular signaling Mol Cell Endocrinol 331 2011 179 184
-
(2011)
Mol Cell Endocrinol
, vol.331
, pp. 179-184
-
-
Slinger, E.1
Langemeijer, E.2
Siderius, M.3
Vischer, H.F.4
Smit, M.J.5
-
124
-
-
0033995792
-
Epstein-barr virus-Associated malignancies: Epidemiologic patterns and etiologic implications
-
J.L. Hsu, and S.L. Glaser Epstein-barr virus-Associated malignancies: epidemiologic patterns and etiologic implications Crit Rev Oncol Hematol 34 2000 27 53
-
(2000)
Crit Rev Oncol Hematol
, vol.34
, pp. 27-53
-
-
Hsu, J.L.1
Glaser, S.L.2
-
125
-
-
0034003417
-
Opioids suppress chemokine-mediated migration of monkey neutrophils and monocytes - An instant response
-
T. Miyagi, L.F. Chuang, K.M. Lam, H. Kung, J.M. Wang, and B.I. Osburn Opioids suppress chemokine-mediated migration of monkey neutrophils and monocytes - an instant response Immunopharmacology 47 2000 53 62
-
(2000)
Immunopharmacology
, vol.47
, pp. 53-62
-
-
Miyagi, T.1
Chuang, L.F.2
Lam, K.M.3
Kung, H.4
Wang, J.M.5
Osburn, B.I.6
-
126
-
-
2542423686
-
Differential desensitization, receptor phosphorylation, beta-Arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7
-
T.A. Kohout, S.L. Nicholas, S.J. Perry, G. Reinhart, S. Junger, and R.S. Struthers Differential desensitization, receptor phosphorylation, beta-Arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7 J Biol Chem 279 2004 23214 23222
-
(2004)
J Biol Chem
, vol.279
, pp. 23214-23222
-
-
Kohout, T.A.1
Nicholas, S.L.2
Perry, S.J.3
Reinhart, G.4
Junger, S.5
Struthers, R.S.6
-
127
-
-
0141679065
-
Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium
-
T. Baltus, K.S. Weber, Z. Johnson, A.E. Proudfoot, and C. Weber Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium Blood 102 2003 1985 1988
-
(2003)
Blood
, vol.102
, pp. 1985-1988
-
-
Baltus, T.1
Weber, K.S.2
Johnson, Z.3
Proudfoot, A.E.4
Weber, C.5
-
128
-
-
84873905373
-
Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR
-
Epub ahead of print
-
J. Vinet, M. van Zwam, I.M. Dijkstra, N. Brouwer, H.R. van Weering, and A. Watts Inhibition of CXCR3-mediated chemotaxis by the human chemokine receptor-like protein CCX-CKR Br J Pharmacol 2012 Epub ahead of print
-
(2012)
Br J Pharmacol
-
-
Vinet, J.1
Van Zwam, M.2
Dijkstra, I.M.3
Brouwer, N.4
Van Weering, H.R.5
Watts, A.6
-
129
-
-
84873911308
-
Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes
-
Epub ahead of print
-
A.O. Watts, M.M. van Lipzig, W.C. Jaeger, R.M. Seeber, M. van Zwam, and J. Vinet Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes Br J Pharmacol 2012 Epub ahead of print
-
(2012)
Br J Pharmacol
-
-
Watts, A.O.1
Van Lipzig, M.M.2
Jaeger, W.C.3
Seeber, R.M.4
Van Zwam, M.5
Vinet, J.6
|