Characterization of the homodimerization interface and functional hotspots of the CXCR4 chemokine receptor

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 8, 2012, Pages 1919-1928

  Rodríguez, David ^a   Gutiérrez de Terán, Hugo ^a  

^a Instituto de Salud Carlos III   (Spain)

Author keywords

Binding site; Chemokine; CXCR4; GPCR; HIV; Homodimer; Hotspot residues; MD simulations

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; LYSOZYME;

ARTICLE; BACTERIOPHAGE T4; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIGAND BINDING; LIPID BILAYER; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE;

AMINO ACIDS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CXCR4;

EID: 84863780022     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24099     Document Type: Article

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