Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme

EMBO Journal

Volumn 29, Issue 23, 2010, Pages 3952-3966

  Ren, Min ^a   Guo, Qing ^a   Guo, Liang ^b   Lenz, Martin ^c   Qian, Feng ^d   Koenen, Rory R ^e   Xu, Hua ^d   Schilling, Alexander B ^d   Weber, Christian ^e   Ye, Richard D ^d   Dinner, Aaron R ^c   Tang, Wei Jen ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

chemokine; chemotactic gradient; insulin degrading enzyme; MIP 1 polymerization; X ray crystallography

Indexed keywords

CHEMOKINE RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1; PROTEIN CCL3; PROTEIN CCL4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; DEPOLYMERIZATION; INSULIN DEGRADATION; MATHEMATICAL MODEL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHEMOKINE CCL3; CHEMOKINE CCL4; CRYSTALLOGRAPHY, X-RAY; HUMANS; INSULYSIN; MACROPHAGE INFLAMMATORY PROTEINS; MALE; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERIZATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION;

EID: 78649694743     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.256     Document Type: Article

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