Interleukin-6 induces the generation of IL-10-producing Tr1 cells and suppresses autoimmune tissue inflammation

Journal of Autoimmunity

Volumn 40, Issue 1, 2013, Pages 28-44

  Jin, Jun O ^a   Han, Xiaozhe ^a   Yu, Qing ^a  

^a FORSYTH INSTITUTE   (United States)

Author keywords

Autoimmune disease; Immune regulatory; Inflammation; Interleukin 10; Interleukin 6; Tr1 cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 21; INTERLEUKIN 27; INTERLEUKIN 6; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENTERITIS; GENETIC TRAIT; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T CELL DEPLETION;

ANIMALS; ANTIGENS, CD3; AUTOIMMUNITY; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; HOMEODOMAIN PROTEINS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-2; INTERLEUKIN-6; INTERLEUKINS; INTESTINES; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; T-LYMPHOCYTES, REGULATORY;

EID: 84873742482     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.07.009     Document Type: Article

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