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Volumn 108, Issue 2, 2013, Pages 402-408

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix

Author keywords

CA IX; E cadherin; GLUT 1; Tumour hypoxia; Tumour invasiveness; Uterine cervix cancers

Indexed keywords

CARBONATE DEHYDRATASE IX; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR; KI 67 ANTIGEN; UVOMORULIN;

EID: 84873705320     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.570     Document Type: Article
Times cited : (15)

References (46)
  • 2
    • 0036488221 scopus 로고    scopus 로고
    • Glucose deprivation and hypoxia increase the expression of the GLUT1 glucose transporter via a specific mRNA cis-acting regulatory element
    • DOI 10.1046/j.0022-3042.2001.00756.x
    • Boado RJ, Pardridge WM (2002) Glucose deprivation and hypoxia increase the expression of the GLUT1 glucose transporter via a specific mRNA cisacting regulatory element. J Neurochem 80: 552-554. (Pubitemid 36383039)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.3 , pp. 552-554
    • Boado, R.J.1    Pardridge, W.M.2
  • 4
    • 49349113654 scopus 로고    scopus 로고
    • Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes
    • Caberg JH, Hubert PM, Begon DY, Herfs MF, Roncarati PJ, Boniver JJ, Delvenne PO (2008) Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes. Carcinogenesis 29: 1441-1447.
    • (2008) Carcinogenesis , vol.29 , pp. 1441-1447
    • Caberg, J.H.1    Hubert, P.M.2    Begon, D.Y.3    Herfs, M.F.4    Roncarati, P.J.5    Boniver, J.J.6    Delvenne, P.O.7
  • 5
    • 0038509263 scopus 로고    scopus 로고
    • Cutaneous breast cancer deposits show distinct growth patterns with different degrees of angiogenesis, hypoxia and fibrin deposition
    • DOI 10.1046/j.1365-2559.2003.01629.x
    • Colpaert CG, Vermeulen PB, van Beest P, Soubry A, Goovaerts G, Dirix LY, Harris AL, van Marck EA (2003) Cutaneous breast cancer deposits show distinct growth patterns with different degrees of angiogenesis, hypoxia and fibrin deposition. Histopathology 42: 530-540. (Pubitemid 36688146)
    • (2003) Histopathology , vol.42 , Issue.6 , pp. 530-540
    • Colpaert, C.G.1    Vermeulen, P.B.2    Van Beest, P.3    Soubry, A.4    Goovaerts, G.5    Dirix, L.Y.6    Harris, A.L.7    Van Marck, E.A.8
  • 6
    • 0000014184 scopus 로고
    • Decreased mutual adhesiveness, a property of cells from squamous cell carcinomas
    • Coman DR (1944) Decreased mutual adhesiveness, a property of cells from squamous cell carcinomas. Cancer Res 4: 625-629.
    • (1944) Cancer Res , vol.4 , pp. 625-629
    • Coman, D.R.1
  • 8
    • 70549102512 scopus 로고    scopus 로고
    • Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress
    • Dewhirst MW (2009) Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress. Radiat Res 172: 653-665.
    • (2009) Radiat Res , vol.172 , pp. 653-665
    • Dewhirst, M.W.1
  • 9
    • 34447321623 scopus 로고    scopus 로고
    • Loss of epithelium cadherin expression is associated with reduced overall survival and disease-free survival in early-stage squamous cell cervical carcinoma
    • DOI 10.1111/j.1525-1438.2007.00876.x
    • Dursun P, Yuce K, Usubutun A, Ayhan A (2007) Loss of epithelium cadherin expression is associated with reduced overall survival and disease-free survival in early-stage squamous cell cervical carcinoma. Int J Gynecol Cancer 17: 843-850. (Pubitemid 47063327)
    • (2007) International Journal of Gynecological Cancer , vol.17 , Issue.4 , pp. 843-850
    • Dursun, P.1    Yuce, K.2    Usubutun, A.3    Ayhan, A.4
  • 11
    • 11444269451 scopus 로고    scopus 로고
    • E-cadherin, CD44 and CD44v6 in squamous intraepithelial lesions and invasive carcinomas of the uterine cervix: An immunohistochemical study
    • DOI 10.1159/000081729
    • Faleiro-Rodrigues C, Lopes C (2004) E-cadherin, CD44 and CD44v6 in squamous intraepithelial lesions and invasive carcinomas of the uterine cervix: An immunohistochemical study. Pathobiology 71: 329-336. (Pubitemid 40082314)
    • (2004) Pathobiology , vol.71 , Issue.6 , pp. 329-336
    • Faleiro-Rodrigues, C.1    Lopes, C.2
  • 12
    • 40949114950 scopus 로고    scopus 로고
    • Role and regulation of prolyl hydroxylase domain proteins
    • DOI 10.1038/cdd.2008.10, PII CDD200810, The biology of Hypoxia-inducible factors
    • Fong GH, Takeda K (2008) Role and regulation of prolyl hydroxylase domain proteins. Cell Death Differ 15: 635-641. (Pubitemid 351405066)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 635-641
    • Fong, G.-H.1    Takeda, K.2
  • 13
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • DOI 10.1038/nrc1075
    • Friedl P, Wolf K (2003) Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer 3: 362-374. (Pubitemid 37328856)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 14
    • 36749013537 scopus 로고    scopus 로고
    • Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
    • DOI 10.1038/ncb1658, PII NCB1658
    • Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E (2007) Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 9: 1392-1400. (Pubitemid 350201752)
    • (2007) Nature Cell Biology , vol.9 , Issue.12 , pp. 1392-1400
    • Gaggioli, C.1    Hooper, S.2    Hidalgo-Carcedo, C.3    Grosse, R.4    Marshall, J.F.5    Harrington, K.6    Sahai, E.7
  • 16
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Höckel M, Schlenger K, Aral B, Mitze M, Scha?ffer U, Vaupel P (1996) Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 56: 4509-4515. (Pubitemid 26330463)
    • (1996) Cancer Research , vol.56 , Issue.19 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 18
    • 0026356726 scopus 로고
    • Oxygenation of carcinomas of the uterine cervix: Evaluation by computerized O2 tension measurements
    • Höckel M, Schlenger K, Knoop C, Vaupel P (1991) Oxygenation of carcinomas of the uterine cervix: Evaluation by computerized O2 tension measurements. Cancer Res 51: 6098-6102.
    • (1991) Cancer Res , vol.51 , pp. 6098-6102
    • Höckel, M.1    Schlenger, K.2    Knoop, C.3    Vaupel, P.4
  • 19
    • 36248948574 scopus 로고    scopus 로고
    • Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX
    • DOI 10.1038/labinvest.3700680, PII 3700680
    • Iakovlev VV, Pintilie M, Morrison A, Fyles AW, Hill RP, Hedley DW (2007) Effect of distributional heterogeneity on the analysis of tumor hypoxia based on carbonic anhydrase IX. Lab Invest 87: 1206-1217. (Pubitemid 350126705)
    • (2007) Laboratory Investigation , vol.87 , Issue.12 , pp. 1206-1217
    • Iakovlev, V.V.1    Pintilie, M.2    Morrison, A.3    Fyles, A.W.4    Hill, R.P.5    Hedley, D.W.6
  • 20
    • 0141760411 scopus 로고    scopus 로고
    • Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells
    • Imai T, Horiuchi A, Wang C, Oka K, Ohira S, Nikaido T, Konishi I (2003) Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol 163: 1437-1447. (Pubitemid 37175091)
    • (2003) American Journal of Pathology , vol.163 , Issue.4 , pp. 1437-1447
    • Imai, T.1    Horiuchi, A.2    Wang, C.3    Oka, K.4    Ohira, S.5    Nikaido, T.6    Konishi, I.7
  • 21
    • 0031106052 scopus 로고    scopus 로고
    • E-cadherin and integrin cell adhesion molecule expression in invasive and in situ carcinoma of the cervix
    • DOI 10.1006/gyno.1996.4578
    • Jeffers MD, Paxton J, Bolger B, Richmond JA, Kennedy JH, McNicol AM (1997) E-cadherin and integrin cell adhesion molecule expression in invasive and in sitücarcinoma of the cervix. Gynecol Oncol 64: 481-486. (Pubitemid 27120441)
    • (1997) Gynecologic Oncology , vol.64 , Issue.3 , pp. 481-486
    • Jeffers, M.D.1    Paxton, J.2    Bolger, B.3    Richmond, J.A.4    Kennedy, J.H.5    McNicol, A.M.6
  • 22
    • 0033997568 scopus 로고    scopus 로고
    • Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: Comparative measurements using EF5 binding and the Eppendorf needle electrode
    • DOI 10.1016/S0360-3016(99)00342-9, PII S0360301699003429
    • Jenkins WT, Evans SM, Koch CJ (2000) Hypoxia and necrosis in rat 9 L glioma and Morris 7777 hepatoma tumors: Comparative measurements using EF5 binding and the Eppendorf needle electrode. Int J Radiat Oncol Biol Phys 46: 1005-1017. (Pubitemid 30114415)
    • (2000) International Journal of Radiation Oncology Biology Physics , vol.46 , Issue.4 , pp. 1005-1017
    • Jenkins, W.T.1    Evans, S.M.2    Koch, C.J.3
  • 23
    • 0036682009 scopus 로고    scopus 로고
    • Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1α stabilization: A role for phosphatidylinositol 3′-kinase
    • Kaluz S, Kaluzova M, Chrastina A, Olive PL, Pastorekova S, Pastorek J, Lerman MI, Stanbridge EJ (2002) Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1a stabilization: A role for phosphatidylinositol 3'-kinase. Cancer Res 62: 4469-4477. (Pubitemid 34827310)
    • (2002) Cancer Research , vol.62 , Issue.15 , pp. 4469-4477
    • Kaluz, S.1    Kaluzova, M.2    Chrastina, A.3    Olive, P.L.4    Pastorekova, S.5    Pastorek, J.6    Lerman, M.I.7    Stanbridge, E.J.8
  • 24
    • 27644477840 scopus 로고    scopus 로고
    • Effect of low glutamine/glucose on hypoxia-induced elevation of hypoxia-inducible factor-1a in human pancreatic cancer MiaPaCa-2 and human prostatic cancer DU-145 cells
    • Kwon SJ, Lee YJ (2005) Effect of low glutamine/glucose on hypoxia-induced elevation of hypoxia-inducible factor-1a in human pancreatic cancer MiaPaCa-2 and human prostatic cancer DU-145 cells. Clin Cancer Res 11: 4694-4670.
    • (2005) Clin Cancer Res , vol.11 , pp. 4694-4670
    • Kwon, S.J.1    Lee, Y.J.2
  • 25
    • 51049109014 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical cancer: Correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation
    • Lee MY, ChoüCY, Tang MJ, Shen MR (2008) Epithelial-mesenchymal transition in cervical cancer: Correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation. Clin Cancer Res 14: 4743-4750.
    • (2008) Clin Cancer Res , vol.14 , pp. 4743-4750
    • Lee, M.Y.1    Choü, C.Y.2    Tang, M.J.3    Shen, M.R.4
  • 26
    • 0030825252 scopus 로고    scopus 로고
    • Oxygen tension in human tumours measured with polarographic needle electrodes and its relationship to vascular density, necrosis and hypoxia
    • DOI 10.1016/S0167-8140(97)01920-8, PII S0167814097019208
    • Lyng H, Sundfor K, Rofstad EK (1997) Oxygen tension in human tumours measured with polarographic needle electrodes and its relationship to vascular density, necrosis and hypoxia. Radiother Oncol 44: 163-169. (Pubitemid 27345204)
    • (1997) Radiotherapy and Oncology , vol.44 , Issue.2 , pp. 163-169
    • Lyng, H.1    Sundfor, K.2    Rofstad, E.K.3
  • 27
    • 78650803945 scopus 로고    scopus 로고
    • GLUT-1 staining of squamous cell carcinomas of the uterine cervix identifies a novel element of invasion
    • Mayer A, Höckel M, Horn LC, Schmidberger H, Vaupel P (2011) GLUT-1 staining of squamous cell carcinomas of the uterine cervix identifies a novel element of invasion. Int J Oncol 38: 145-150.
    • (2011) Int J Oncol , vol.38 , pp. 145-150
    • Mayer, A.1    Höckel, M.2    Horn, L.C.3    Schmidberger, H.4    Vaupel, P.5
  • 28
    • 27144451824 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression end tumor oxygenation status do not correlate at the microregional level in locally advanced cancers of the uterine cervix
    • DOI 10.1158/1078-0432.CCR-05-0869
    • Mayer A, Höckel M, Vaupel P (2005a) Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally advanced cancers of the uterine cervix. Clin Cancer Res 11: 7220-7225. (Pubitemid 41507678)
    • (2005) Clinical Cancer Research , vol.11 , Issue.20 , pp. 7220-7225
    • Mayer, A.1    Hockel, M.2    Vaupel, P.3
  • 29
    • 33748199697 scopus 로고    scopus 로고
    • Endogenous hypoxia markers in locally advanced cancers of the uterine cervix: Reality or wishful thinking?
    • DOI 10.1007/s00066-006-1525-9
    • Mayer A, Höckel M, Vaupel P (2006) Endogenous hypoxia markers in locally advanced cancers of the uterine cervix: Reality or wishful thinking? Strahlenther Onkol 182: 501-510. (Pubitemid 44316238)
    • (2006) Strahlentherapie und Onkologie , vol.182 , Issue.9 , pp. 501-510
    • Mayer, A.1    Hockel, M.2    Vaupel, P.3
  • 30
    • 49649084777 scopus 로고    scopus 로고
    • Lack of hypoxic response in uterine leiomyomas despite severe tissue hypoxia
    • Mayer A, Höckel M, Wree A, Leo C, Horn LC, Vaupel P (2008) Lack of hypoxic response in uterine leiomyomas despite severe tissue hypoxia. Cancer Res 68: 4719-4726.
    • (2008) Cancer Res , vol.68 , pp. 4719-4726
    • Mayer, A.1    Höckel, M.2    Wree, A.3    Leo, C.4    Horn, L.C.5    Vaupel, P.6
  • 31
    • 17644425583 scopus 로고    scopus 로고
    • Microregional expression of glucose transporter-1 and oxygenation status: Lack of correlation in locally advanced cervical cancers
    • DOI 10.1158/1078-0432.CCR-04-2344
    • Mayer A, Höckel M, Wree A, Vaupel P (2005b) Microregional expression of glucose transporter-1 and oxygenation status: Lack of correlation in locally advanced cervical cancers. Clin Cancer Res 11: 2768-2773. (Pubitemid 40569479)
    • (2005) Clinical Cancer Research , vol.11 , Issue.7 , pp. 2768-2773
    • Mayer, A.1    Hockel, M.2    Wree, A.3    Vaupel, P.4
  • 32
    • 3242725198 scopus 로고    scopus 로고
    • HIF activation by pH-dependent nucleolar sequestration of VHL
    • DOI 10.1038/ncb1144
    • Mekhail K, Gunaratnam L, Bonicalzi ME, Lee S (2004) HIF activation by pH-dependent nucleolar sequestration of VHL. Nat Cell Biol 6: 642-647. (Pubitemid 38960922)
    • (2004) Nature Cell Biology , vol.6 , Issue.7 , pp. 642-647
    • Mekhail, K.1    Gunaratnam, L.2    Bonicalzi, M.-E.3    Lee, S.4
  • 36
    • 0037459077 scopus 로고    scopus 로고
    • Sticky business: Orchestrating cellular signals at adherens junctions
    • DOI 10.1016/S0092-8674(03)00108-9
    • Perez-Moreno M, Jamora C, Fuchs E (2003) Sticky business: Orchestrating cellular signals at adherens junctions. Cell 112: 535-548. (Pubitemid 36263085)
    • (2003) Cell , vol.112 , Issue.4 , pp. 535-548
    • Perez-Moreno, M.1    Jamora, C.2    Fuchs, E.3
  • 38
    • 84859445000 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
    • Semenza GL (2012) Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci 33: 207-214.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 207-214
    • Semenza, G.L.1
  • 39
    • 3543148396 scopus 로고    scopus 로고
    • E-cadherin and catenins in early squamous cervical carcinoma
    • DOI 10.1016/j.ygyno.2004.05.046, PII S0090825804003440
    • van de Putte G, Kristensen GB, Baekelandt M, Lie AK, Holm R (2004) E-cadherin and catenins in early squamous cervical carcinoma. Gynecol Oncol 94: 521-527. (Pubitemid 39028907)
    • (2004) Gynecologic Oncology , vol.94 , Issue.2 , pp. 521-527
    • Van De Putte, G.1    Kristensen, G.B.2    Baekelandt, M.3    Lie, A.K.4    Holm, R.5
  • 40
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: Significance and impact on clinical outcome
    • DOI 10.1007/s10555-007-9055-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
    • Vaupel P, Mayer A (2007) Hypoxia in cancer: Significance and impact on clinical outcome. Cancer Metastasis Rev 26: 225-239. (Pubitemid 47101660)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.2 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 41
    • 1642565876 scopus 로고    scopus 로고
    • Tumor hypoxia and malignant progression
    • DOI 10.1016/S0076-6879(04)81023-1
    • Vaupel P, Mayer A, Höckel M (2004) Tumor hypoxia and malignant progression. Methods Enzymol 381: 335-354. (Pubitemid 38401518)
    • (2004) Methods in Enzymology , vol.381 , pp. 335-354
    • Vaupel, P.1    Mayer, A.2    Hockel, M.3
  • 42
    • 0029041448 scopus 로고
    • Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma
    • Vessey CJ, Wilding J, Folarin N, Hirano S, Takeichi M, Soutter P, Stamp GW, Pignatelli M (1995) Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma. J Pathol 176: 151-159.
    • (1995) J Pathol , vol.176 , pp. 151-159
    • Vessey, C.J.1    Wilding, J.2    Folarin, N.3    Hirano, S.4    Takeichi, M.5    Soutter, P.6    Stamp, G.W.7    Pignatelli, M.8
  • 43
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92: 5510-5514.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 44
    • 0036320934 scopus 로고    scopus 로고
    • 2- regulated gene expression
    • DOI 10.1096/fj.01-0944rev
    • Wenger RH (2002) Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J 16: 1151-1162. (Pubitemid 34815403)
    • (2002) FASEB Journal , vol.16 , Issue.10 , pp. 1151-1162
    • Wenger, R.H.1
  • 45
    • 33645758275 scopus 로고    scopus 로고
    • Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
    • Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G (2006) Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9: 261-272.
    • (2006) Cancer Cell , vol.9 , pp. 261-272
    • Wicki, A.1    Lehembre, F.2    Wick, N.3    Hantusch, B.4    Kerjaschki, D.5    Christofori, G.6


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