-
1
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 1989;49:6449-65.
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
3
-
-
78651122032
-
Studies on the exchange of fluids between host and tumor. I. A method for growing "tissue-isolated" tumors in laboratory animals
-
Gullino PM, Grantham FH. Studies on the exchange of fluids between host and tumor. I. A method for growing "tissue-isolated" tumors in laboratory animals. J Natl Cancer Inst 1961;27:679-93.
-
(1961)
J Natl Cancer Inst
, vol.27
, pp. 679-693
-
-
Gullino, P.M.1
Grantham, F.H.2
-
6
-
-
0028784650
-
Correlation of high lactate levels in human cervical cancer with incidence of metastasis
-
Schwickert G, Walenta S, Sundfor K, Rofstad EK, Mueller-Klieser W. Correlation of high lactate levels in human cervical cancer with incidence of metastasis. Cancer Res 1995;55:4757-9.
-
(1995)
Cancer Res
, vol.55
, pp. 4757-4759
-
-
Schwickert, G.1
Walenta, S.2
Sundfor, K.3
Rofstad, E.K.4
Mueller-Klieser, W.5
-
7
-
-
0031029634
-
Correlation of high lactate levels in head and neck tumors with incidence of metastasis
-
Walenta S, Salameh A, Lyng H, et al. Correlation of high lactate levels in head and neck tumors with incidence of metastasis. Am J Pathol 1997;150:409-15.
-
(1997)
Am J Pathol
, vol.150
, pp. 409-415
-
-
Walenta, S.1
Salameh, A.2
Lyng, H.3
-
8
-
-
0021732164
-
The relevance of tumour pH to the treatment of malignant disease
-
Wike-Hooley JL, Haveman J, Reinhold HS. The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 1984;2:343-66.
-
(1984)
Radiother Oncol
, vol.2
, pp. 343-366
-
-
Wike-Hooley, J.L.1
Haveman, J.2
Reinhold, H.S.3
-
9
-
-
0011488224
-
Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation
-
Sciandra JJ, Subjeck JR, Hughes CS. Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation. Proc Natl Acad Sci U S A 1984;81:4843-7.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 4843-4847
-
-
Sciandra, J.J.1
Subjeck, J.R.2
Hughes, C.S.3
-
10
-
-
0022352547
-
Differential induction of glucose-regulated and heat shock proteins: Effects of pH and sulfhydryl-reducing agents on chicken embryo cells
-
Whelan SA, Hightower LE. Differential induction of glucose-regulated and heat shock proteins: effects of pH and sulfhydryl-reducing agents on chicken embryo cells. J Cell Physiol 1985;125:251-8.
-
(1985)
J Cell Physiol
, vol.125
, pp. 251-258
-
-
Whelan, S.A.1
Hightower, L.E.2
-
11
-
-
0025999040
-
Induction of the proliferative phenotype in differentiated myogenic cells by hypoxia
-
Butler AJ, Eagleton MJ, Wang D, et al. Induction of the proliferative phenotype in differentiated myogenic cells by hypoxia. J Biol Chem 1991;266:18250-8.
-
(1991)
J Biol Chem
, vol.266
, pp. 18250-18258
-
-
Butler, A.J.1
Eagleton, M.J.2
Wang, D.3
-
12
-
-
0025868208
-
The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells
-
Murphy BJ, Laderoute KR, Short SM, Sutherland RM. The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells. Br J Cancer 1991;64:69-73.
-
(1991)
Br J Cancer
, vol.64
, pp. 69-73
-
-
Murphy, B.J.1
Laderoute, K.R.2
Short, S.M.3
Sutherland, R.M.4
-
13
-
-
0025774184
-
Oxygen regulated 80 kDa protein and glucose regulated 78 kDa protein are identical
-
Roll DE, Murphy BJ, Laderoute KR, Sutherland RM, Smith HC. Oxygen regulated 80 kDa protein and glucose regulated 78 kDa protein are identical. Mol Cell Biochem 1991;103:141-8.
-
(1991)
Mol Cell Biochem
, vol.103
, pp. 141-148
-
-
Roll, D.E.1
Murphy, B.J.2
Laderoute, K.R.3
Sutherland, R.M.4
Smith, H.C.5
-
14
-
-
0022536553
-
Stress protein systems of mammalian cells
-
Subjeck JR, Shyy TT. Stress protein systems of mammalian cells. Am J Physiol 1986;250:C1-17.
-
(1986)
Am J Physiol
, vol.250
-
-
Subjeck, J.R.1
Shyy, T.T.2
-
15
-
-
0024273450
-
Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
-
Goldberg MA, Dunning SP, Bunn HF. Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science 1988;242:1412-5.
-
(1988)
Science
, vol.242
, pp. 1412-1415
-
-
Goldberg, M.A.1
Dunning, S.P.2
Bunn, H.F.3
-
16
-
-
0028095127
-
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
-
Goldberg MA, Schneider TJ. Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 1994;269:4355-9.
-
(1994)
J Biol Chem
, vol.269
, pp. 4355-4359
-
-
Goldberg, M.A.1
Schneider, T.J.2
-
17
-
-
0029879211
-
Hypoglycemia-induced AP-1 transcription factor and basic fibroblast growth factor gene expression in multidrug resistant human breast carcinoma MCF-7/ADR cells
-
Galoforo SS, Berns CM, Erdos G, Corry PM, Lee YJ. Hypoglycemia-induced AP-1 transcription factor and basic fibroblast growth factor gene expression in multidrug resistant human breast carcinoma MCF-7/ADR cells. Mol Cell Biochem 1996;155:163-71.
-
(1996)
Mol Cell Biochem
, vol.155
, pp. 163-171
-
-
Galoforo, S.S.1
Berns, C.M.2
Erdos, G.3
Corry, P.M.4
Lee, Y.J.5
-
18
-
-
0037376877
-
Angiogenesis and apoptosis
-
Folkman J. Angiogenesis and apoptosis. Semin Cancer Biol 2003;13:159-67.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 159-167
-
-
Folkman, J.1
-
19
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-9.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
-
20
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. Mechanisms of angiogenesis. Nature 1997;386:671-4.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
21
-
-
0028147863
-
Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo
-
Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vitro and in vivo. Lab Invest 1994;71:374-9.
-
(1994)
Lab Invest
, vol.71
, pp. 374-379
-
-
Minchenko, A.1
Bauer, T.2
Salceda, S.3
Caro, J.4
-
22
-
-
0030779901
-
Regulation of glutamine synthetase in human breast carcinoma cells and experimental tumors
-
Collins CL, Wasa M, Souba WW, Abcouwer SF. Regulation of glutamine synthetase in human breast carcinoma cells and experimental tumors. Surgery 1997;122:451-64.
-
(1997)
Surgery
, vol.122
, pp. 451-464
-
-
Collins, C.L.1
Wasa, M.2
Souba, W.W.3
Abcouwer, S.F.4
-
23
-
-
2942557118
-
Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress
-
Marjon PL, Bobrovnikova-Marjon EV, Abcouwer SF. Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol Cancer 2004;3:4.
-
(2004)
Mol Cancer
, vol.3
, pp. 4
-
-
Marjon, P.L.1
Bobrovnikova-Marjon, E.V.2
Abcouwer, S.F.3
-
24
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
-
Shweiki D, Neeman M, Itin A, Keshet E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc Natl Acad Sci U S A 1995;92:768-72.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
Keshet, E.4
-
25
-
-
0029082384
-
Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
-
Stein I, Neeman M, Shweiki D, Itin A, Keshet E. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol Cell Biol 1995; 15:5363-8.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5363-5368
-
-
Stein, I.1
Neeman, M.2
Shweiki, D.3
Itin, A.4
Keshet, E.5
-
26
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 1996; 16:4604-13.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
-
29
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
-
Ohh M, Park CW, Ivan M, et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein. Nat Cell Biol 2000;2:423-7.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
-
31
-
-
0035917808
-
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, et al. Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation. Science 2001;292:468-72.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
-
32
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 2001;294:1337-40.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
33
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein AC, Gleadle JM, McNeill LA, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001;107:43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
-
34
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003;9:677-84.
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
35
-
-
0029803552
-
An essential role for p300/CBP in the cellular response to hypoxia
-
Arany Z, Huang LE, Eckner R, et al. An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci U S A 1996;93:12969-73.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 12969-12973
-
-
Arany, Z.1
Huang, L.E.2
Eckner, R.3
-
36
-
-
0031835957
-
Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein
-
Ebert BL, Bunn HF. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein. Mol Cell Biol 1998;18:4089-96.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4089-4096
-
-
Ebert, B.L.1
Bunn, H.F.2
-
37
-
-
0031587821
-
Recruitment of p300/CBP in p53-dependent signal pathways
-
Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, Kelly K. Recruitment of p300/CBP in p53-dependent signal pathways. Cell 1997;89:1175-84.
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.S.5
Kelly, K.6
-
38
-
-
0031023139
-
p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription
-
Puri PL, Avantaggiati ML, Balsano C, et al. p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription. EMBO J 1997; 16:369-83.
-
(1997)
EMBO J
, vol.16
, pp. 369-383
-
-
Puri, P.L.1
Avantaggiati, M.L.2
Balsano, C.3
-
39
-
-
0022298588
-
Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo
-
Kallinowskil F, Davel S, Vaupell P, Baessler KH, Wagner K. Glucose, lactate, and ketone body utilization by human mammary carcinomas in vivo. Adv Exp Med Biol 1985;191:763-73.
-
(1985)
Adv Exp Med Biol
, vol.191
, pp. 763-773
-
-
Kallinowskil, F.1
Davel, S.2
Vaupell, P.3
Baessler, K.H.4
Wagner, K.5
-
40
-
-
0344642991
-
Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis
-
Roslin M, Henriksson R, Bergstrom P, Ungerstedt U, Bergenheim AT. Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis. J Neurooncol 2003;61:151-60.
-
(2003)
J Neurooncol
, vol.61
, pp. 151-160
-
-
Roslin, M.1
Henriksson, R.2
Bergstrom, P.3
Ungerstedt, U.4
Bergenheim, A.T.5
-
41
-
-
0022932386
-
Glucose metabolism in human gliomas: Correspondence of in situ and in vitro metabolic rates and altered energy metabolism
-
Galarraga J, Loreck DJ, Graham JF, et al. Glucose metabolism in human gliomas: correspondence of in situ and in vitro metabolic rates and altered energy metabolism. Metab Brain Dis 1986;1:279-91.
-
(1986)
Metab Brain Dis
, vol.1
, pp. 279-291
-
-
Galarraga, J.1
Loreck, D.J.2
Graham, J.F.3
-
44
-
-
0033823130
-
Tissue responses to ischemia: Local and remote responses for preserving perfusion of ischemic muscle
-
Isner JM. Tissue responses to ischemia: local and remote responses for preserving perfusion of ischemic muscle. J Clin Invest 2000;106:615-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 615-619
-
-
Isner, J.M.1
-
45
-
-
2642515744
-
HIF at the crossroads between ischemia and carcinogenesis
-
Paul SA, Simons JW, Mabjeesh NJ. HIF at the crossroads between ischemia and carcinogenesis. J Cell Physiol 2004;200:20-30.
-
(2004)
J Cell Physiol
, vol.200
, pp. 20-30
-
-
Paul, S.A.1
Simons, J.W.2
Mabjeesh, N.J.3
-
46
-
-
0033803047
-
Surviving ischemia: Adaptive responses mediated by hypoxia-inducible factor 1
-
Semenza GL. Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1. J Clin Invest 2000;106:809-12.
-
(2000)
J Clin Invest
, vol.106
, pp. 809-812
-
-
Semenza, G.L.1
-
47
-
-
3142708680
-
Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: Role of nuclear factor-κB and activating protein-1
-
Bobrovnikova-Marjon EV, Marjon PL, Barbash O, Vander Jagt DL, Abcouwer SF. Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-κB and activating protein-1. Cancer Res 2004;64:4858-69.
-
(2004)
Cancer Res
, vol.64
, pp. 4858-4869
-
-
Bobrovnikova-Marjon, E.V.1
Marjon, P.L.2
Barbash, O.3
Vander Jagt, D.L.4
Abcouwer, S.F.5
-
48
-
-
4344660420
-
NF-κB and AP-1 connection: Mechanism of NF-κB-dependent regulation of AP-1 activity
-
Fujioka S, Niu J, Schmidt C, et al. NF-κB and AP-1 connection: mechanism of NF-κB-dependent regulation of AP-1 activity. Mol Cell Biol 2004;24:7806-19.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7806-7819
-
-
Fujioka, S.1
Niu, J.2
Schmidt, C.3
-
49
-
-
20544465985
-
Regulation of transcription and translation by hypoxia
-
Liu L, Simon MC. Regulation of transcription and translation by hypoxia. Cancer Biol Ther 2004;3:492-7.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 492-497
-
-
Liu, L.1
Simon, M.C.2
-
50
-
-
0029756791
-
Adaptation of chondrocytes to low oxygen tension: Relationship between hypoxia and cellular metabolism
-
Rajpurohit R, Koch CJ, Tao Z, Teixeira CM, Shapiro IM. Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism. J Cell Physiol 1996;168:424-32.
-
(1996)
J Cell Physiol
, vol.168
, pp. 424-432
-
-
Rajpurohit, R.1
Koch, C.J.2
Tao, Z.3
Teixeira, C.M.4
Shapiro, I.M.5
-
51
-
-
0024308958
-
Changes of amino acid by the deprivation of energy sources in the cerebral cortex
-
Ando M, Itoh T. Changes of amino acid by the deprivation of energy sources in the cerebral cortex. Brain Dev 1989;11:169-74.
-
(1989)
Brain Dev
, vol.11
, pp. 169-174
-
-
Ando, M.1
Itoh, T.2
-
52
-
-
0030973825
-
Glucose deprivation-induced cytotoxicity in drug resistant human breast carcinoma MCF-7/ADR cells: Role of c-myc and bcl-2 in apoptotic cell death
-
Lee YJ, Galoforo SS, Berns CM, Tong WP, Kim HR, Corry PM. Glucose deprivation-induced cytotoxicity in drug resistant human breast carcinoma MCF-7/ADR cells: role of c-myc and bcl-2 in apoptotic cell death. J Cell Sci 1997;110:681-6.
-
(1997)
J Cell Sci
, vol.110
, pp. 681-686
-
-
Lee, Y.J.1
Galoforo, S.S.2
Berns, C.M.3
Tong, W.P.4
Kim, H.R.5
Corry, P.M.6
-
53
-
-
0032408067
-
Energetic and morphological plasticity of C6 glioma cells grown on 3-D support; effect of transient glutamine deprivation
-
Martin M, Beauvoit B, Voisin PJ, Canioni P, Guerin B, Rigoulet M. Energetic and morphological plasticity of C6 glioma cells grown on 3-D support; effect of transient glutamine deprivation. J Bioenerg Biomembr 1998;30:565-78.
-
(1998)
J Bioenerg Biomembr
, vol.30
, pp. 565-578
-
-
Martin, M.1
Beauvoit, B.2
Voisin, P.J.3
Canioni, P.4
Guerin, B.5
Rigoulet, M.6
-
54
-
-
0029823598
-
Cell susceptibility to apoptosis by glutamine deprivation and rescue: Survival and apoptotic death in cultured lymphoma-leukemia cell lines
-
Petronini PG, Urbani S, Alfieri R, Borghetti AF, Guidotti GG. Cell susceptibility to apoptosis by glutamine deprivation and rescue: survival and apoptotic death in cultured lymphoma-leukemia cell lines. J Cell Physiol 1996;169:175-85.
-
(1996)
J Cell Physiol
, vol.169
, pp. 175-185
-
-
Petronini, P.G.1
Urbani, S.2
Alfieri, R.3
Borghetti, A.F.4
Guidotti, G.G.5
-
55
-
-
0343777395
-
Efficient translation of mouse hypoxia-inducible factor-1α under normoxic and hypoxic conditions
-
Gorlach A, Camenisch G, Kvietikova I, Vogt L, Wenger RH, Gassmann M. Efficient translation of mouse hypoxia-inducible factor-1α under normoxic and hypoxic conditions. Biochim Biophys Acta 2000; 1493:125-34.
-
(2000)
Biochim Biophys Acta
, vol.1493
, pp. 125-134
-
-
Gorlach, A.1
Camenisch, G.2
Kvietikova, I.3
Vogt, L.4
Wenger, R.H.5
Gassmann, M.6
-
56
-
-
0026463868
-
Amino acid sequence of the human protein synthesis initiation factor elF-4γ
-
Yan R, Rychlik W, Etchison D, Rhoads RE. Amino acid sequence of the human protein synthesis initiation factor elF-4γ. J Biol Chem 1992;267:23226-31.
-
(1992)
J Biol Chem
, vol.267
, pp. 23226-23231
-
-
Yan, R.1
Rychlik, W.2
Etchison, D.3
Rhoads, R.E.4
|