Tumor biomarkers in cervical cancer: Focus on Ki-67 proliferation factor and E-cadherin expression

Romanian Journal of Morphology and Embryology

Volumn 50, Issue 3, 2008, Pages 413-418

  Ancuta E ^a   Ancuţa, Codrina ^b   Cozma, Laurette Graziella ^c   Iordache, Cristina ^b   Anghelache Lupaşcu, Ivona ^a,b   Anton, E ^a,b   Carasevici, E ^b,c   Chirieac, Rodica ^b  

^a Research Department 'Cuza Vod ' Clinical Hospital   (Romania)

^b GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c University Hospital Sf Spiridon   (Romania)

Author keywords

Biomarkers; Cervical cancer; E cadherin; Ki 67

Indexed keywords

CADHERIN; KI 67 ANTIGEN; TUMOR MARKER;

ADULT; ARTICLE; CANCER INVASION; CARCINOMA IN SITU; CELL PROLIFERATION; FEMALE; HUMAN; METABOLISM; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA; UTERINE CERVIX TUMOR;

ADULT; CADHERINS; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; FEMALE; HUMANS; KI-67 ANTIGEN; NEOPLASM INVASIVENESS; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

HUMAN PAPILLOMAVIRUS;

EID: 70349187419     PISSN: 12200522     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. HATCH D. K., FU Y. S., Cervical and vaginal cancer. In: BEREK J. S. (ed), Novak's Gynecology, Callisto Medical Press, Turkey, 1999, 1111-1155.
2. PANDELI R., COZMA G. L., ANTON C., NEGURA A., Tumour angiogenesis, as a predictor in cervix carcinoma, J Prev Med, 2005, 13(3-4):72-77.
3. DE BOER C. J., VAN DORST E., VAN KRIEKEN H., JANSEN-VAN RHIJN C. M., WARNAAR S. O., FLEUREN J. G., LITVINOV S. V., Changing roles of cadherins and catenins during progression of squamous intraepithelial lesions in the uterine cervix, Am J Pathol, 1999, 155(2):505-515.
4. BIRCHMEIER W., BEHRENS J., Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness, Biochim Biophys Acta, 1994, 1198(1):11-26.
5. PANJKOVIĆ M., IVKOVIĆ-KAPICL T., Ki-67 expression in squamous intraepithelial lesions of the uterine cervix, Arch Oncol, 2006, 14(1-2):23-25.
6. ROSS W., HALL P. A., Ki67: from antibody to molecule to understanding?, Clin Mol Pathol, 1995, 48(3):M113-M117.
7. YIM E. K., PARK J. S., Biomarkers in cervical cancer, Biomarker Insights, 2006, 2:215-225.
8. NAKANO T., OKA K., Differential values of Ki-67 index and mitotic index of proliferating cell population. An assessment of cell cycle and prognosis in radiation therapy for cervical cancer, Cancer, 1993, 72(8):2401-2408.
9. KUO K. T., CHANG H. C., HSIAO C. H., LIN M. C., Increased Ki-67 proliferative index and absence of P16INK4 in CIN-HPV related pathogenic pathways different from cervical squamous intraepithelial lesion, Br J Ophthalmol, 2006, 90(7):894-899.
10. ANJU M., MATI G. M., Assessment of monoclonal antibody MIB-1 labeling indices in cervical intraepithelial lesion of the uterine cervix in paraffin section, J Obst Gyn India, 2008, 58(4):327-332.
11. LONGATTO FILHO A., ALBERGARIA A., PAREDES J., MOREIRA M. A., MILANEZI F., SCHMITT F. C., P-cadherin expression in glandular lesions of the uterine cervix detected by liquid-based cytology, Cytopathology, 2005, 16(2):88-93.
12. GARZETTI G. G., CIAVATTINI A., LUCARINI G., GOTERI G., DE NICTOLIS M., BIAGINI G., MIB-1 immunostaining in cervical carcinoma of young patients, Gynecol Oncol, 1997, 67(2):184-187.
13. HSU S. M., RAINE L., FANGER H., Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures, J Histochem Cytochem, 1981, 29(4):577-580.
14. MAEDA M. Y., SIMÕES M., WAKAMATSU A., LONGATTO FILHO A. L., OYAFUSO M., DE MELLO E. S., OTTA M. M., ALVES V. A., Relevance of the rates of PCNA, Ki-67 and p53 expression according to the epithelial compartment in cervical lesions, Pathologica, 2001, 93(3):189-195.
15. KRUSE A. J., BAAK J. P. A., DE BRUIN P. C., JIWA M., SNIJDERS W. P., BOODT P. J., FONS G., HOUBEN P. W., THE H. S., Ki-67 immunoquantitation in cervical intraepithelial neoplasia (CIN): a sensitive marker for grading, J Pathol, 2001, 193(1):48-54.
16. AL-SALEH W., DELVENNE P., GREIMERS R., FRIDMAN V., DOYEN J., BONIVER J., Assessment of Ki-67 antigen immunostaining in squamous intraepithelial lesion of the uterine cervix. Correlation with the histologic grade and human papillomavirus type, Am J Clin Pathol, 1995, 104(2):154-160.
17. GIBBONS D., FOGT F., KASZNICA J., HOLDEN J., NIKULASSON S., Comparison of topoisomerase II alpha and MIB-1 expression in uterine cervical squamous lesions, Mod Pathol, 1997, 10(5):409-413.
18. KEATING J. T., CVIKO A., RIETHDORF S., RIETHDORF L., QUADE B. J., SUN D., DUENSING S., SHEETS E. E, MUNGER K., CRUM C. P., Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia, Am J Surg Pathol, 2001, 25(7):884-891.
19. HARRIS T. G., KULASINGAM S. L., KIVIAT N. B., MAO C., AGOFF S. N., FENG Q., KOUTSKY L. A., Cigarette smoking, oncogenic human papillomavirus, Ki-67 antigen, and cervical intraepithelial neoplasia, Am J Epidemiol, 2004, 159(9):834-842
20. TJALMA W., WEYLER J., POLLEFLIET C., BOGERS J., VAN MARCK E., VAN DAM P., BUYTAERT P., The evaluation of proliferative activity in CIN III and microinvasive cervical cancer and its role in recurrence, Eur J Obstet Gynecol Reprod Biol, 2001, 94(2):270-275.
21. LITVINOV S. V., BALZAR M., WINTER M. J., BAKKER H. A. M., BRIAIRE-DE BRUIJN I. H., PRINS F., FLEUREN G. J., WARNAAR S. O., Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins, J Cell Biol, 1997, 139(5):1337-1348.
22. SHIOZAKI H., OKA H., INOUE M., TAMURA S., MONDEN M., E-cadherin mediated adhesion system in cancer cells, Cancer, 1996, 77(8 Suppl):1605-1613.
23. VESSEY C. J., WILDING J., FOLARIN N., HIRANO S., TAKEICHI M., SOUTTER P., STAMP G. W. H., PIGNATELLI M., Altered expression and function of E-cadherin in cervical intraepithelial neoplasia and invasive squamous cell carcinoma, J Pathol, 1995, 176(2):151-159.
24. CARRILHO C., GOUVEIA P., CANTEL M., ALBERTO M., BUANE L., DAVID L., Characterization of human papilloma- virus infection, P53 and Ki-67 expression in cervix cancer of Mozambican women, Pathol Res Pract, 2003, 199(5):303-311.