Long-term treatment with EXf, a peptide analog of Exendin-4, improves β-cell function and survival in diabetic KKAy mice

Peptides

Volumn 40, Issue , 2013, Pages 123-132

  Hou, Guo Jiang ^a   Li, Cai Na ^a   Liu, Shuai Nan ^a   Huan, Yi ^a   Liu, Quan ^a   Sun, Su Juan ^a   Li, Lin Yi ^a   Hou, Shao Cong ^a   Shen, Zhu Fang ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Cell function; Cell survival; Apoptosis; Diabetic KKAy mice; EXf; Proliferation

Indexed keywords

BIM PROTEIN; CASPASE 3; CASPASE 9; EXENDIN 4; EXF PROTEIN; GLUCAGON; GLUCOSE; INSULIN; KI 67 ANTIGEN; PEPTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PDX 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INFUSION; GLUCOSE INTOLERANCE; GLYCEMIC CONTROL; INSULIN RELEASE; LONG TERM CARE; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE INTOLERANCE; INSULIN; INSULIN-SECRETING CELLS; KI-67 ANTIGEN; MICE; MICE, INBRED NOD; PEPTIDE FRAGMENTS; PEPTIDES; PROTO-ONCOGENE PROTEINS C-AKT; TRIGLYCERIDES; VENOMS;

MUS;

EID: 84873703005     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.01.010     Document Type: Article

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