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Volumn 628, Issue 1-3, 2010, Pages 261-267

Biological activity of EXf, a peptide analogue of exendin-4

Author keywords

(Mice); Glucose tolerance; Incretin mimetic; Insulin; NIT 1 cells

Indexed keywords

ANTIDIABETIC AGENT; EXENDIN 4 DERIVATIVE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUTAMATE SODIUM; INCRETIN; UNCLASSIFIED DRUG;

EID: 73649147322     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.11.021     Document Type: Article
Times cited : (10)

References (19)
  • 1
    • 4344667831 scopus 로고    scopus 로고
    • A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
    • Baggio L.L., Huang Q., Brown T.J., and Drucker D.J. A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis. Diabetes 53 (2004) 2492-2500
    • (2004) Diabetes , vol.53 , pp. 2492-2500
    • Baggio, L.L.1    Huang, Q.2    Brown, T.J.3    Drucker, D.J.4
  • 2
    • 0024216182 scopus 로고
    • Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes
    • Bruce D.G., Chisholm D.J., Storlien L.H., and Kraegen E.W. Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes. Diabetes 37 (1988) 736-744
    • (1988) Diabetes , vol.37 , pp. 736-744
    • Bruce, D.G.1    Chisholm, D.J.2    Storlien, L.H.3    Kraegen, E.W.4
  • 4
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Exenatide-113 Clinical Study Group
    • Buse J.B., Henry R.R., Han J., Kim D.D., Fineman M.S., Baron A.D., and Exenatide-113 Clinical Study Group. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 27 (2004) 2628-2635
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 5
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • DeFronzo R.A., Ratner R.E., Han J., Kim D.D., Fineman M.S., and Baron A.D. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 28 (2005) 1092-1100
    • (2005) Diabetes Care , vol.28 , pp. 1092-1100
    • DeFronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 6
    • 4344713643 scopus 로고    scopus 로고
    • Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia
    • Degn K.B., Brock B., Juhl C.B., Djurhuus C.B., Grubert J., Kim D., Han J., Taylor K., Fineman M., and Schmitz O. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia. Diabetes 53 (2004) 2397-2403
    • (2004) Diabetes , vol.53 , pp. 2397-2403
    • Degn, K.B.1    Brock, B.2    Juhl, C.B.3    Djurhuus, C.B.4    Grubert, J.5    Kim, D.6    Han, J.7    Taylor, K.8    Fineman, M.9    Schmitz, O.10
  • 7
    • 0034944773 scopus 로고    scopus 로고
    • The importance of first-phase insulin secretion: implications for the therapy of type 2 diabetes mellitus
    • Del Prato S., and Tiengo A. The importance of first-phase insulin secretion: implications for the therapy of type 2 diabetes mellitus. Diabetes Metab. Res. Rev. 17 (2001) 164-174
    • (2001) Diabetes Metab. Res. Rev. , vol.17 , pp. 164-174
    • Del Prato, S.1    Tiengo, A.2
  • 9
    • 0036965113 scopus 로고    scopus 로고
    • The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes
    • Egan J.M., Clocquet A.R., and Elahi D. The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes. J. Clin. Endocrinol. Metab. 87 (2002) 1282-1290
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1282-1290
    • Egan, J.M.1    Clocquet, A.R.2    Elahi, D.3
  • 10
    • 0026648961 scopus 로고
    • Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom
    • Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
    • Eng J., Kleinman W.A., Singh L., Singh G., and Raufman J.P. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J. Biol. Chem. 267 (1992) 7402-7405
    • (1992) J. Biol. Chem. , vol.267 , pp. 7402-7405
    • Eng, J.1    Kleinman, W.A.2    Singh, L.3    Singh, G.4    Raufman, J.P.5
  • 11
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells
    • Göke R., Fehmann H.C., Linn T., Schmidt H., Krause M., Eng J., and Göke B. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J. Biol. Chem. 268 (1993) 19650-19655
    • (1993) J. Biol. Chem. , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Göke, B.7
  • 12
    • 0036869408 scopus 로고    scopus 로고
    • Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1
    • Holst J.J. Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1. Diabetes Metab. Res. Rev. 18 (2002) 430-441
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. 430-441
    • Holst, J.J.1
  • 13
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall D.M., Riddle M.C., Rosenstock J., Zhuang D., Kim D.D., Fineman M.S., and Baron A.D. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 28 (2005) 1083-1091
    • (2005) Diabetes Care , vol.28 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3    Zhuang, D.4    Kim, D.D.5    Fineman, M.S.6    Baron, A.D.7
  • 14
    • 12244260114 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) in the treatment of diabetes
    • Nauck M.A. Glucagon-like peptide 1 (GLP-1) in the treatment of diabetes. Horm. Metab. Res. 36 (2004) 852-858
    • (2004) Horm. Metab. Res. , vol.36 , pp. 852-858
    • Nauck, M.A.1
  • 15
    • 19444382837 scopus 로고    scopus 로고
    • Incretin mimetics and DPP-IV inhibitors for the treatment of type 2 diabetes
    • Nielsen L.L. Incretin mimetics and DPP-IV inhibitors for the treatment of type 2 diabetes. Drug Discov. Today 10 (2005) 703-710
    • (2005) Drug Discov. Today , vol.10 , pp. 703-710
    • Nielsen, L.L.1
  • 16
    • 0033947157 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element
    • Skoglund G., Hussain M.A., and Holz G.G. Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element. Diabetes 49 (2000) 1156-1164
    • (2000) Diabetes , vol.49 , pp. 1156-1164
    • Skoglund, G.1    Hussain, M.A.2    Holz, G.G.3
  • 17
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice
    • Talsania T., Anini Y., Siu S., Drucker D.J., and Brubaker P.L. Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology 146 (2005) 3748-3756
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 18
    • 0027425034 scopus 로고
    • Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor
    • Thorens B., Porret A., Bühler L., Deng S.P., Morel P., and Widmann C. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 42 (1993) 1678-1682
    • (1993) Diabetes , vol.42 , pp. 1678-1682
    • Thorens, B.1    Porret, A.2    Bühler, L.3    Deng, S.P.4    Morel, P.5    Widmann, C.6
  • 19
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor
    • Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 6 (1969) 24-25
    • (1969) Ann. Clin. Biochem. , vol.6 , pp. 24-25
    • Trinder, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.