메뉴 건너뛰기




Volumn 41, Issue 3, 2013, Pages 2060-2071

Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase

Author keywords

[No Author keywords available]

Indexed keywords

1 NITROPYRENE; [DEOXYGUANOSINE 8 YL] 1 AMINOPYRENE; ADENINE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE DERIVATIVE; DNA DIRECTED DNA POLYMERASE GAMMA; GUANINE; PYRENE; UNCLASSIFIED DRUG;

EID: 84873677422     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks1296     Document Type: Article
Times cited : (22)

References (56)
  • 1
    • 0034649702 scopus 로고    scopus 로고
    • Fine particulate air pollution and mortality in 20 U.S cities 1987- 1994
    • Samet,J.M., Dominici,F., Curriero,F.C., Coursac,I. and Zeger,S.L. (2000) Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N. Engl. J. Med., 343, 1742-1749.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1742-1749
    • Coursac, I.1    Zeger, S.L.2
  • 2
    • 0028048849 scopus 로고
    • Gas-chromatographic mass-spectrometric determination of nitro polycyclic aromatic-hydrocarbons in airborne particulate matter from workplace atmospheres contaminated with diesel exhaust
    • Scheepers,P.T.J., Velders,D.D., Martens,M.H.J., Noordhoek,J. and Bos,R.P. (1994) Gas-chromatographic mass-spectrometric determination of nitro polycyclic aromatic-hydrocarbons in airborne particulate matter from workplace atmospheres contaminated with diesel exhaust. J. Chromatogr. A, 677, 107-121.
    • (1994) J. Chromatogr. A , vol.677 , pp. 107-121
    • Noordhoek, J.1    Bos, R.P.2
  • 3
    • 37249044369 scopus 로고    scopus 로고
    • Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1- aminopyrene in mammalian cells
    • Watt,D.L., Utzat,C.D., Hilario,P. and Basu,A.K. (2007) Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells. Chem. Res. Toxicol., 20, 1658-1664.
    • (2007) Chem. Res. Toxicol. , vol.20 , pp. 1658-1664
    • Hilario, P.1    Basu, A.K.2
  • 4
    • 67649336393 scopus 로고    scopus 로고
    • Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells
    • Andersson,H., Piras,E., Demma,J., Hellman,B. and Brittebo,E. (2009) Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells. Toxicology, 262, 57-64.
    • (2009) Toxicology , vol.262 , pp. 57-64
    • Hellman, B.1    Brittebo, E.2
  • 5
    • 45049088724 scopus 로고    scopus 로고
    • 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells
    • Asare,N., Landvik,N., Lagadic-Gossmann,D., Rissel,M., Tekpli,X., Ask,K., Lag,M. and Holme,J. (2008) 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells. Toxicol Applied Pharmacol., 230, 175-186.
    • (2008) Toxicol Applied Pharmacol. , vol.230 , pp. 175-186
    • Lag, M.1    Holme, J.2
  • 6
    • 0021325373 scopus 로고
    • Induction of rat mammary-gland tumors by 1-Nitropyrene, a recently recognized environmental mutagen.GEN
    • Hirose,M., Lee,M.S., Wang,C.Y. and King,C.M. (1984) Induction of rat mammary-gland tumors by 1-Nitropyrene, a recently recognized environmental mutagen.GEN. Cancer Res., 44, 1158-1162.
    • (1984) Cancer Res. , vol.44 , pp. 1158-1162
    • Wang, C.Y.1    King, C.M.2
  • 7
    • 0023761110 scopus 로고
    • A study of chemical carcinogenesis .114. comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-Aminopyrene administered by gavage to Sprague-Dawley rats
    • Elbayoumy,K., Rivenson,A., Johnson,B., Dibello,J., Little,P. and Hecht,S.S. (1988) A study of chemical carcinogenesis .114. comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-Aminopyrene administered by gavage to Sprague-Dawley rats. Cancer Res., 48, 4256-4260.
    • (1988) Cancer Res. , vol.48 , pp. 4256-4260
    • Little, P.1    Hecht, S.S.2
  • 8
    • 0023873175 scopus 로고
    • DNA-binding by 1-nitropyrene and 1,6-dinitropyrene invitro and invivo - Effects of nitroreductase induction
    • Djuric,Z., Fifer,E., Yamazoe,Y. and Beland,F. (1988) DNA-binding by 1-nitropyrene and 1,6-dinitropyrene invitro and invivo - effects of nitroreductase induction. Carcinogenesis, 9, 357-364.
    • (1988) Carcinogenesis , vol.9 , pp. 357-364
    • Yamazoe, Y.1    Beland, F.2
  • 9
    • 65249138294 scopus 로고    scopus 로고
    • Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase
    • Sherrer,S., Brown,J., Pack,L., Jasti,V., Fowler,J., Basu,A. and Suo,Z. (2009) Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. J. Biol. Chem, 284, 6379-6388.
    • (2009) J. Biol. Chem , vol.284 , pp. 6379-6388
    • Basu, A.1    Suo, Z.2
  • 10
    • 0034745389 scopus 로고    scopus 로고
    • Patterns of p53 G->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
    • Hainaut,P. and Pfeifer,G.P. (2001) Patterns of p53 G->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis, 22, 367-374.
    • (2001) Carcinogenesis , vol.22 , pp. 367-374
    • Hainaut, P.1    Pfeifer, G.P.2
  • 11
    • 13544276569 scopus 로고    scopus 로고
    • Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication
    • Hsu,G.W., Huang,X., Luneva,N.P., Geacintov,N.E. and Beese,L.S. (2005) Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. J. Biol. Chem., 280, 3764-3770.
    • (2005) J. Biol. Chem. , vol.280 , pp. 3764-3770
    • Geacintov, N.E.1    Beese, L.S.2
  • 12
    • 35648951199 scopus 로고    scopus 로고
    • What a difference a decade makes: Insights into translesion DNA synthesis
    • Yang,W. and Woodgate,R. (2007) What a difference a decade makes: insights into translesion DNA synthesis. Proc. Natl Acad. Sci. USA, 104, 15591-15598.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 15591-15598
    • Yang, W.1    Woodgate, R.2
  • 13
    • 0037205001 scopus 로고    scopus 로고
    • Specialized DNA polymerases, cellular survival, and the genesis of mutations
    • Friedberg,E.C., Wagner,R. and Radman,M. (2002) Specialized DNA polymerases, cellular survival, and the genesis of mutations. Science, 296, 1627-1630.
    • (2002) Science , vol.296 , pp. 1627-1630
    • Wagner, R.1    Radman, M.2
  • 14
    • 84857411787 scopus 로고    scopus 로고
    • Y-family DNA polymerases and their role in tolerance of cellular DNA damage
    • Sale,J.E., Lehmann,A.R. and Woodgate,R. (2012) Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat. Rev. Mol. Cell Biol., 13, 141-152.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 141-152
    • Lehmann, A.R.1    Woodgate, R.2
  • 15
    • 0035812849 scopus 로고    scopus 로고
    • Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication
    • Ling,H., Boudsocq,F., Woodgate,R. and Yang,W. (2001) Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell, 107, 91-102.
    • (2001) Cell , vol.107 , pp. 91-102
    • Woodgate, R.1    Yang, W.2
  • 16
    • 3142674288 scopus 로고    scopus 로고
    • Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing
    • Nair,D.T., Johnson,R.E., Prakash,S., Prakash,L. and Aggarwal,A.K. (2004) Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature, 430, 377-380.
    • (2004) Nature , vol.430 , pp. 377-380
    • Prakash, L.1    Aggarwal, A.K.2
  • 17
    • 77953924511 scopus 로고    scopus 로고
    • Structure and mechanism of human DNA polymerase eta
    • Biertumpfel,C., Zhao,Y., Kondo,Y., Ramon-Maiques,S., Gregory,M., Lee,J.Y., Masutani,C., Lehmann,A.R., Hanaoka,F. and Yang,W. (2010) Structure and mechanism of human DNA polymerase eta. Nature, 465, 1044-1048.
    • (2010) Nature , vol.465 , pp. 1044-1048
    • Hanaoka, F.1    Yang, W.2
  • 18
    • 33847208855 scopus 로고    scopus 로고
    • Human DNA polymerase kappa encircles DNA: Implications for mismatch extension and lesion bypass
    • Lone,S., Townson,S.A., Uljon,S.N., Johnson,R.E., Brahma,A., Nair,D.T., Prakash,S., Prakash,L. and Aggarwal,A.K. (2007) Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol. Cell, 25, 601-614.
    • (2007) Mol. Cell , vol.25 , pp. 601-614
    • Prakash, L.1    Aggarwal, A.K.2
  • 19
    • 25844440534 scopus 로고    scopus 로고
    • Rev1 employs a novel mechanism of DNA synthesis using a protein template
    • Nair,D.T., Johnson,R.E., Prakash,L., Prakash,S. and Aggarwal,A.K. (2005) Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science, 309, 2219-2222.
    • (2005) Science , vol.309 , pp. 2219-2222
    • Prakash, S.1    Aggarwal, A.K.2
  • 20
    • 43049105331 scopus 로고    scopus 로고
    • Snapshots of a Y-family DNA polymerase in replication: Substrate-induced conformational transitions and implications for fidelity of Dpo4
    • Wong,J.H., Fiala,K.A., Suo,Z. and Ling,H. (2008) Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. J. Mol. Biol., 379, 317-330.
    • (2008) J. Mol. Biol. , vol.379 , pp. 317-330
    • Suo, Z.1    Ling, H.2
  • 21
    • 58449104506 scopus 로고    scopus 로고
    • Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA
    • Xing,G., Kirouac,K., Shin,Y.J., Bell,S.D. and Ling,H. (2009) Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Mol. Microbiol., 71, 678-691.
    • (2009) Mol. Microbiol. , vol.71 , pp. 678-691
    • Bell, S.D.1    Ling, H.2
  • 22
    • 0035162925 scopus 로고    scopus 로고
    • Why do cells have multiple error-prone DNA polymerases? Environ
    • Friedberg,E.C. (2001) Why do cells have multiple error-prone DNA polymerases? Environ. Mol. Mutagen., 38, 105-110.
    • (2001) Mol. Mutagen. , vol.38 , pp. 105-110
    • Friedberg, E.C.1
  • 23
    • 61649116694 scopus 로고    scopus 로고
    • Synthesis of oligonucleotides containing 20-deoxyguanosine adducts of nitropyrenes
    • Colis,L.C., Chakraborti,D., Hilario,P., McCarty,C. and Basu,A.K. (2009) Synthesis of oligonucleotides containing 20-deoxyguanosine adducts of nitropyrenes. Nucleosides Nucleotides Nucleic Acids, 28, 67-77.
    • (2009) Nucleosides Nucleotides Nucleic Acids , vol.28 , pp. 67-77
    • McCarty, C.1    Basu, A.K.2
  • 24
    • 67349236998 scopus 로고    scopus 로고
    • Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota
    • Kirouac,K.N. and Ling,H. (2009) Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. EMBO J, 28, 1644-1654.
    • (2009) EMBO J , vol.28 , pp. 1644-1654
    • Kirouac, K.N.1    Ling, H.2
  • 25
    • 25844477090 scopus 로고    scopus 로고
    • Purification of a synthetic oligonucleotide by anion exchange chromatography: Method optimisation and scale-up
    • Shanagar,J. (2005) Purification of a synthetic oligonucleotide by anion exchange chromatography: method optimisation and scale-up. J. Biochem. Biophys. Methods, 64, 216-225.
    • (2005) J. Biochem. Biophys. Methods , vol.64 , pp. 216-225
    • Shanagar, J.1
  • 26
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode
    • Otwinowski,Z. and Minor,W. (1997) Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol., 276, 307-326.
    • (1997) Methods Enzymol. , vol.276 , pp. 307-326
    • Otwinowski, Z.1    Minor, W.2
  • 27
    • 23844546311 scopus 로고    scopus 로고
    • Likelihood-enhanced fast translation functions
    • McCoy,A.J., Grosse-Kunstleve,R.W., Storoni,L.C. and Read,R.J. (2005) Likelihood-enhanced fast translation functions. Acta Crystallogr. D. Biol. Crystallogr., 61, 458-464.
    • (2005) Acta Crystallogr. , vol.61 , pp. 458-464
    • Storoni, L.C.1    Read, R.J.2
  • 28
    • 76449098262 scopus 로고    scopus 로고
    • PHENIX: A comprehensive Python-based system for macromolecular structure solution
    • Adams,P.D., Afonine,P.V., Bunkoczi,G., Chen,V.B., Davis,I.W., Echols,N., Headd,J.J., Hung,L.W., Kapral,G.J., Grosse-Kunstleve,R.W. et al. (2010) PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D. Biol. Crystallogr., 66, 213-221.
    • (2010) Acta Crystallogr. D. Biol. Crystallogr. , vol.66 , pp. 213-221
    • Grosse-Kunstleve, R.W.1
  • 29
    • 33645158291 scopus 로고    scopus 로고
    • TLSMD web server for the generation of multi-group TLS models
    • Painter,J. and Merritt,E. (2006) TLSMD web server for the generation of multi-group TLS models. J. Chromatogr., 39, 109-111.
    • (2006) J. Chromatogr. , vol.39 , pp. 109-111
    • Painter, J.1    Merritt, E.2
  • 30
    • 13244281317 scopus 로고    scopus 로고
    • Coot: Model-building tools for molecular graphics
    • Emsley,P. and Cowtan,K. (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr. D. Biol. Crystallogr., 60, 2126-2132.
    • (2004) Acta Crystallogr. , vol.60 , pp. 2126-2132
    • Emsley, P.1    Cowtan, K.2
  • 32
    • 84858644903 scopus 로고    scopus 로고
    • Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases
    • Sherrer,S.M., Sanman,L.E., Xia,C.X., Bolin,E.R., Malik,C.K., Efthimiopoulos,G., Basu,A.K. and Suo,Z. (2012) Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. Chem. Res. Toxicol., 25, 730-740.
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 730-740
    • Basu, A.K.1    Suo, Z.2
  • 33
    • 26444528004 scopus 로고    scopus 로고
    • Human DNA polymerase iota incorporates dCTP opposite template G via a G.C+Hoogsteen base pair
    • Nair,D.T., Johnson,R.E., Prakash,L., Prakash,S. and Aggarwal,A.K. (2005) Human DNA polymerase iota incorporates dCTP opposite template G via a G.C+Hoogsteen base pair. Structure, 13, 1569-1577.
    • (2005) Structure , vol.13 , pp. 1569-1577
    • Prakash, S.1    Aggarwal, A.K.2
  • 34
    • 77953921670 scopus 로고    scopus 로고
    • Structural basis for the suppression of skin cancers by DNA polymerase eta
    • Silverstein,T.D., Johnson,R.E., Jain,R., Prakash,L., Prakash,S. and Aggarwal,A.K. (2010) Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature, 465, 1039-1043.
    • (2010) Nature , vol.465 , pp. 1039-1043
    • Prakash, S.1    Aggarwal, A.K.2
  • 35
    • 77953618270 scopus 로고    scopus 로고
    • Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4
    • Wong,J.H., Brown,J.A., Suo,Z., Blum,P., Nohmi,T. and Ling,H. (2010) Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J., 29, 2059-2069.
    • (2010) EMBO J. , vol.29 , pp. 2059-2069
    • Nohmi, T.1    Ling, H.2
  • 36
    • 0041864009 scopus 로고    scopus 로고
    • Replication of a cys-syn thymine dimer at atomic resolution
    • Ling,H., Boudsocq,F., Plosky,B.S., Woodgate,R. and Yang,W. (2003) Replication of a cys-syn thymine dimer at atomic resolution. Nature, 424, 1083-1087.
    • (2003) Nature , vol.424 , pp. 1083-1087
    • Woodgate, R.1    Yang, W.2
  • 37
    • 58549109864 scopus 로고    scopus 로고
    • Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing?
    • Donny-Clark,K., Shapiro,R. and Broyde,S. (2009) Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Biochemistry, 48, 7-18.
    • (2009) Biochemistry , vol.48 , pp. 7-18
    • Shapiro, R.1    Broyde, S.2
  • 38
    • 0029817865 scopus 로고    scopus 로고
    • Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex
    • Mao,B., Vyas,R.R., Hingerty,B.E., Broyde,S., Basu,A.K. and Patel,D.J. (1996) Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. Biochemistry, 35, 12659-12670.
    • (1996) Biochemistry , vol.35 , pp. 12659-12670
    • Basu, A.K.1    Patel, D.J.2
  • 39
    • 0033578343 scopus 로고    scopus 로고
    • Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex
    • Gu,Z., Gorin,A., Krishnasamy,R., Hingerty,B.E., Basu,A.K., Broyde,S. and Patel,D.J. (1999) Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Biochemistry, 38, 10843-10854.
    • (1999) Biochemistry , vol.38 , pp. 10843-10854
    • Broyde, S.1    Patel, D.J.2
  • 40
    • 35448977252 scopus 로고    scopus 로고
    • A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment
    • Bauer,J., Xing,G., Yagi,H., Sayer,J.M., Jerina,D.M. and Ling,H. (2007) A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Proc. Natl Acad. Sci. USA, 104, 14905-14910.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 14905-14910
    • Jerina, D.M.1    Ling, H.2
  • 41
    • 1442355023 scopus 로고    scopus 로고
    • Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase
    • Ling,H., Sayer,J.M., Plosky,B.S., Yagi,H., Boudsocq,F., Woodgate,R., Jerina,D.M. and Yang,W. (2004) Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proc. Natl Acad. Sci. USA, 101, 2265-2269.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2265-2269
    • Jerina, D.M.1    Yang, W.2
  • 42
    • 0034654495 scopus 로고    scopus 로고
    • Factors contributing to aromatic stacking in water: Evaluation in the context of DNA
    • Guckian,K.M., Schweitzer,B.A., Ren,R.X., Sheils,C.J., Tahmassebi,D.C. and Kool,E.T. (2000) Factors contributing to aromatic stacking in water: evaluation in the context of DNA. J. Am. Chem. Soc., 122, 2213-2222.
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 2213-2222
    • Tahmassebi, D.C.1    Kool, E.T.2
  • 43
    • 33845638804 scopus 로고    scopus 로고
    • Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase
    • Fiala,K.A., Brown,J.A., Ling,H., Kshetry,A.K., Zhang,J., Taylor,J.S., Yang,W. and Suo,Z. (2007) Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. J. Mol. Biol., 365, 590-602.
    • (2007) J. Mol. Biol. , vol.365 , pp. 590-602
    • Yang, W.1    Suo, Z.2
  • 44
    • 0029924011 scopus 로고    scopus 로고
    • Site-specific frame-shift mutagenesis by the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-y1)-1-aminopyrene located in the (CG)3 sequence: Effects of SOS, proofreading, and mismatch repair
    • Malia,S.A., Vyas,R.R. and Basu,A.K. (1996) Site-specific frame-shift mutagenesis by the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-y1)-1-aminopyrene located in the (CG)3 sequence: effects of SOS, proofreading, and mismatch repair. Biochemistry, 35, 4568-4577.
    • (1996) Biochemistry , vol.35 , pp. 4568-4577
    • Vyas, R.R.1    Basu, A.K.2
  • 45
    • 60549096252 scopus 로고    scopus 로고
    • Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals
    • Shachar,S., Ziv,O., Avkin,S., Adar,S., Wittschieben,J., Reissner,T., Chaney,S., Friedberg,E.C., Wang,Z., Carell,T. et al. (2009) Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. EMBO J., 28, 383-393.
    • (2009) EMBO J. , vol.28 , pp. 383-393
    • Carell, T.1
  • 46
    • 77953166792 scopus 로고    scopus 로고
    • Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis
    • Livneh,Z., Ziv,O. and Shachar,S. (2010) Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis. Cell Cycle, 9, 729-735.
    • (2010) Cell Cycle , vol.9 , pp. 729-735
    • Ziv, O.1    Shachar, S.2
  • 47
    • 84864318786 scopus 로고    scopus 로고
    • Overexpression of DNA polymerase iota (Poliota) in esophageal squamous cell carcinoma
    • Zhou,J., Zhang,S., Xie,L., Liu,P., Xie,F., Wu,J., Cao,J. and Ding,W.Q. (2012) Overexpression of DNA polymerase iota (Poliota) in esophageal squamous cell carcinoma. Cancer Sci., 103, 1574-1579.
    • (2012) Cancer Sci. , vol.103 , pp. 1574-1579
    • Cao, J.1    Ding, W.Q.2
  • 48
    • 77953451291 scopus 로고    scopus 로고
    • DNA polymerase iota expression in human lung cancer and its correlation with clinicopathological and prognosis of cancer
    • Zhu,F., Tian,H., Yue,W., Li,S., Tian,X., Qi,L., Zhu,Y. and Hu,W. (2009) DNA polymerase iota expression in human lung cancer and its correlation with clinicopathological and prognosis of cancer. Chinese Journal of Cancer Biotherapy, 16, 503-506.
    • (2009) Chinese Journal of Cancer Biotherapy , vol.16 , pp. 503-506
    • Zhu, Y.1    Hu, W.2
  • 49
    • 12144287580 scopus 로고    scopus 로고
    • Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia
    • Wang,M., Devereux,T.R., Vikis,H.G., McCulloch,S.D., Holliday,W., Anna,C., Wang,Y., Bebenek,K., Kunkel,T.A., Guan,K. et al. (2004) Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Cancer Res., 64, 1924-1931.
    • (2004) Cancer Res. , vol.64 , pp. 1924-1931
    • Guan, K.1
  • 50
    • 34248195087 scopus 로고    scopus 로고
    • Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations
    • Wang,Y., Woodgate,R., McManus,T.P., Mead,S., McCormick,J.J. and Maher,V.M. (2007) Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. Cancer Res., 67, 3018-3026.
    • (2007) Cancer Res. , vol.67 , pp. 3018-3026
    • McCormick, J.J.1    Maher, V.M.2
  • 51
    • 4143081674 scopus 로고    scopus 로고
    • Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis
    • Yang,J., Chen,Z., Liu,Y., Hickey,R.J. and Malkas,L.H. (2004) Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis. Cancer Res., 64, 5597-5607.
    • (2004) Cancer Res. , vol.64 , pp. 5597-5607
    • Hickey, R.J.1    Malkas, L.H.2
  • 52
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
    • Denissenko,M.F., Pao,A., Tang,M. and Pfeifer,G.P. (1996) Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science, 274, 430-432.
    • (1996) Science , vol.274 , pp. 430-432
    • Tang, M.1    Pfeifer, G.P.2
  • 53
    • 0037023677 scopus 로고    scopus 로고
    • Preferential misincorporation of purine nucleotides by human DNA polymerase Z opposite benzo[a]pyrene 7,8-Diol 9,10-epoxide deoxyguanosine adducts
    • Chiapperino,D., Kroth,H., Kramarczuk,I.H., Sayer,J.M., Masutani,C., Hanaoka,F., Jerina,D.M. and Cheh,A.M. (2002) Preferential misincorporation of purine nucleotides by human DNA polymerase Z opposite benzo[a]pyrene 7,8-Diol 9,10-epoxide deoxyguanosine adducts. J. Biol. Chem., 277, 11765-11771.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11765-11771
    • Jerina, D.M.1    Cheh, A.M.2
  • 54
    • 32644435469 scopus 로고    scopus 로고
    • Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells
    • Zhao,B., Wang,J., Geacintov,N.E. and Wang,Z. (2006) Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Nucleic Acids Res., 34, 417-425.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 417-425
    • Geacintov, N.E.1    Wang, Z.2
  • 55
    • 0034917463 scopus 로고    scopus 로고
    • Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of muta mouse
    • Vogel,U., Thein,N., Moller,P. and Wallin,H. (2001) Pharmacological coal tar induces G:C to T:A transversion mutations in the skin of muta mouse. Pharmacol. Toxicol., 89, 30-34.
    • (2001) Pharmacol. Toxicol. , vol.89 , pp. 30-34
    • Moller, P.1    Wallin, H.2
  • 56
    • 0035477426 scopus 로고    scopus 로고
    • Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: Similarities with the p53 mutation spectrum in smoking-associated lung cancers
    • Yoon,J.H., Smith,L.E., Feng,Z., Tang,M., Lee,C.S. and Pfeifer,G.P. (2001) Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers. Cancer Res., 61, 7110-7117.
    • (2001) Cancer Res. , vol.61 , pp. 7110-7117
    • Lee, C.S.1    Pfeifer, G.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.