Systems pharmacology uncovers Janus functions of botanical drugs: Activation of host defense system and inhibition of influenza virus replication

Integrative Biology (United Kingdom)

Volumn 5, Issue 2, 2013, Pages 351-371

  Wang, Xia ^a   Xu, Xue ^a   Li, Yan ^b   Li, Xiuxiu ^a   Tao, Weiyang ^a   Li, Bohui ^a   Wang, Yonghua ^a,c   Yang, Ling ^d  

^a NORTHWEST A F UNIVERSITY   (China)

^b DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^d DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CALCIUM CHANNEL T TYPE; DELTA OPIATE RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FRUCTUS FORSYTHIAE EXTRACT; LONICERA JAPONICA EXTRACT; MACROPHAGE MIGRATION INHIBITION FACTOR; PHOSPHOLIPASE A2; PLANT EXTRACT; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ACUTE PHASE RESPONSE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CHINESE MEDICINE; DEGLYCOSYLATION; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG SAFETY; DRUG TARGETING; FIRST PASS EFFECT; FRUCTUS FORSYTHIAE; FRUIT; HOST CELL; HOST RESISTANCE; HUMAN; HYDROLYSIS; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; INFLUENZA VIRUS; LONICERA JAPONICA; MEDICINAL PLANT; MEMBRANE TRANSPORT; NONHUMAN; PANDEMIC INFLUENZA; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN TARGETING; PURINE METABOLISM; PYRIMIDINE METABOLISM; VIRUS REPLICATION;

ANTIVIRAL AGENTS; COMPUTER SIMULATION; DRUG DISCOVERY; DRUGS, CHINESE HERBAL; IMMUNITY, INNATE; MODELS, BIOLOGICAL; MODELS, CHEMICAL; ORTHOMYXOVIRIDAE; PHYTOTHERAPY; SYSTEMS BIOLOGY; VIRUS REPLICATION;

EID: 84873297322     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib20204b     Document Type: Article

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