A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity

Journal of Neuroscience

Volumn 33, Issue 6, 2013, Pages 2408-2418

  Biasini, Emiliano ^a,b   Unterberger, Ursula ^a   Solomon, Isaac H ^a   Massignan, Tania ^a,b   Senatore, Assunta ^b   Bian, Hejiao ^a   Voigtlaender, Till ^c   Bowman, Frederick P ^a   Bonetto, Valentina ^b   Chiesa, Roberto ^b   Luebke, Jennifer ^a   Toselli, Paul ^a   Harris, David A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CASPASE 3; GLUTAMIC ACID; MICROTUBULE ASSOCIATED PROTEIN 2; PRION PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CALCIUM TRANSPORT; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; EMBRYO; EVOKED RESPONSE; EXCITOTOXICITY; FLUORESCENCE MICROSCOPY; GENOTYPE; GRANULE CELL; IMMUNOFLUORESCENCE TEST; ION CURRENT; MOUSE; NEURAL STEM CELL; NONHUMAN; PATCH CLAMP; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONS; ORGAN CULTURE TECHNIQUES; PRPC PROTEINS;

EID: 84873288135     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3406-12.2013     Document Type: Article

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