Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging

Mechanisms of Ageing and Development

Volumn 134, Issue 1-2, 2013, Pages 53-59

  Ponnappan, Subramaniam ^a   Palmieri, Michela ^b   Sullivan, Dennis H ^a,c   Ponnappan, Usha ^a,b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

Author keywords

Aging; Deubiquitinating enzyme; Proteasome; T lymphocytes; Ubiquitin; USP14

Indexed keywords

DEUBIQUITINATING ENZYME USP14; ENZYME INHIBITOR; ENZYME INHIBITOR IU1; I KAPPA B ALPHA; LACTACYSTIN; PROTEASOME; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AGED; AGING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; T LYMPHOCYTE; UBIQUITINATION;

ACETYLCYSTEINE; ADULT; AGED; AGED, 80 AND OVER; AGING; CYSTEINE PROTEINASE INHIBITORS; FEMALE; HEMOSTASIS; HUMANS; I-KAPPA B PROTEINS; MALE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; T-LYMPHOCYTES; UBIQUITIN; UBIQUITIN THIOLESTERASE;

EID: 84872852734     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.12.007     Document Type: Article

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